Instructions for use of Mycozoral (Method and dosage)
The tablets are taken orally. The instructions for Mycozoral advise doing this during meals. The following dosages are possible for adults and children weighing over 30 kg, depending on the indications:
- systemic mycoses , fungal infections of the skin and gastrointestinal tract: you need to take 200 mg per day, if necessary, you can increase it to 400 mg;
- vaginal candidiasis : 400 mg per day, only 5 days.
For children weighing 15-30 kg, a dosage of 100 mg per day is indicated. Therapy is designed for at least a week until the test results become negative.
As a preventive measure, patients with immunodeficiency should take 400 mg per day (for adults). Children are recommended to take 4-8 mg per 1 kg of weight, but not more than 400 mg.
Average duration of treatment depending on diagnosis:
- systemic candidiasis - 1-2 months;
- fungal infections of the scalp - 1-2 months;
- vaginal candidiasis - 5 days;
- pityriasis versicolor - 10 days;
- fungal nail infections - 6-12 months;
- candidiasis of the oral cavity and skin - 2-3 weeks;
- skin mycoses provoked by dermatophytes - approximately 4 weeks;
- histoplasmosis , paracoccidioidomycosis , coccidioidomycosis – 3-6 months.
The ointment should be applied externally. Apply once a day to and near the affected areas. It must be used until all symptoms of the disease disappear. Treatment of inguinal epidermophytosis lasts on average 2-4 weeks, candidiasis , pityriasis versicolor and mold mycoses - 2-3 weeks, dermatophytosis - 2-6 weeks.
For seborrheic dermatitis, the ointment should be applied 1-2 times a day. Treatment is designed for 2-4 weeks.
For those who use Mycozoral shampoo, the instructions for use indicate that it should be applied to areas of skin and hair affected by fungi, after which, after 3-5 minutes, the product should be rinsed with water. For the treatment of mold mycoses, it is used once a day for 5 days, for prevention - once a day for 3 days.
To get rid of dandruff , 1% shampoo is used every 3-4 days for 8 weeks. For prophylaxis, use only when necessary.
For seborrheic dermatitis , use 2% shampoo 2 times a week. The course lasts 2-4 weeks. For the purpose of prevention, this should be done once every 7 days every 1-2 weeks.
In case of pityriasis versicolor , apply 2% shampoo to the affected and nearby areas of the skin for 3-5 minutes. Upon completion of the procedure, the product is washed off.
Buy Mycozoral ointment 2% 15g in pharmacies
Instructions for use Mycozoral ointment 2% 15g Dosage forms ointment 2% 15mg Synonyms Ketoconazole Ketoconazole DS Livarol Nizoral Perhotal Sebozole Group Antifungal agents - derivatives of imidazole and triazole International nonproprietary name Ketoconazole Composition Active substance - ketoconazole. Manufacturers Akrikhin KhFK (Russia) Pharmacological action Ketoconazole is a synthetic derivative of imidazolediaxolane that has a fungicidal or mycostatic effect. Active against dermatophytes: Trichophyton sp., Microsporum sp., Epidermophyton floccosum, fungi of the genus Candida, as well as against staphylococci and streptococci. Particularly effective against Pityrosporum sp. The mechanism of action is to inhibit the biosynthesis of ergosterol and change the lipid composition of the fungal membrane. Symptomatic improvement is observed very quickly, even before signs of recovery appear. With prolonged local use of the ointment, ketoconazole is not detected in the blood. Side effects Headache, dizziness, drowsiness, hair loss, nausea, vomiting, diarrhea, toxic hepatitis, transient increase in the level of transaminases in the blood, photophobia, gynecomastia, decreased libido, oligospermia, allergic reactions (urticaria, itching, arthralgia, paresthesia, hyperthermia ). Indications for use Local treatment of mycoses caused by fungi sensitive to the drug: dermatomycosis of smooth skin, inguinal athlete's foot, athlete's foot, skin candidiasis, pityriasis versicolor, seborrheic dermatitis caused by Pityrosporum ovale. Contraindications Should not be used if you are hypersensitive to ketoconazole or if the integrity of the skin in the area where the ointment is intended to be applied is compromised. Method of use and dosage For dermatomycosis of smooth skin (tinea groin, athlete's foot, skin candidiasis and pityriasis versicolor), the ointment is applied to the affected area and the area immediately adjacent to it once a day. For seborrheic dermatitis, the ointment is applied to the affected area 1-2 times a day, depending on the severity of the lesion. The average duration of treatment is: for dermatomycosis of smooth skin - 3-4 weeks, for inguinal athlete's foot - 2-4 weeks, for athlete's foot - 4-6 weeks, for infections caused by yeast-like fungi - 2-3 weeks, for pityriasis versicolor - 2 -3 weeks, for seborrheic dermatitis - 2-4 weeks. Treatment should be continued for at least several days after symptoms have disappeared. If clinical improvement is not noted after 4 weeks of treatment, then the diagnosis needs to be clarified. Overdose No information available. Interaction Drug interactions of the drug for external use have not been described. Special instructions The drug is intended for external use only. The ointment is not used in ophthalmic practice. Avoid getting the ointment in your eyes. During treatment, general hygiene rules should be observed. Storage conditions List B. Store in a dry place, out of reach of children, at a temperature not exceeding 15 C.
Contraindications
Contraindications to the use of this product are as follows:
- acute and chronic kidney and liver diseases;
- hypersensitivity to the components of the drug.
The drug is used with caution during pregnancy , breastfeeding , age over 50 years, insufficiency of the adrenal cortex and pituitary gland .
The ointment should not be applied to places where there are wounds and abrasions, i.e. where the integrity of the skin is broken.
Compound
The active substance of the drug is ketoconazole .
Mycozoral tablets have the following auxiliary components: potato starch, low molecular weight medical polyvinylpyrrolidone , talc, lactose, aerosil, magnesium stearate.
The ointment includes such additional ingredients as propylene glycol, castor oil, emulsifier “Lannete SX”, dibunol, sodium carboxymethylcellulose, distilled monoglycerides, nipagin, water.
Mycozoral shampoo contains the following auxiliary components: yellow-orange dye, propylene glycol, diluted hydrochloric acid, sodium laureth sulfate, macrogolglycerol cocoate, water, hydroxypropyl methylcellulose, sodium metabisulfite, imidourea.
Mycozoral price, where to buy
The price of Mycozoral depends on the form of release. In any case, its cost is considered very affordable. The price of Mycozoral tablets is approximately 350 rubles. The price of Mycozoral ointment is about 170 rubles. You can buy shampoo in the same way as tablets or ointment at the pharmacy. Its cost is considered very affordable compared to many expensive dandruff products. The price of Mikozoral shampoo is about 300 rubles.
- Online pharmacies in RussiaRussia
ZdravCity
- Mycozoral ointment 2% 15gAO Akrikhin
RUB 285 order - Mycozoral tab. 0.2g 30pcs JSC Akrikhin
RUR 555 order
Pharmacodynamics and pharmacokinetics
The medicine is active against dermatophytes , dimorphic fungi , yeast fungi , staphylococci , streptococci and eumycetes . Prevents the transformation of Candida albicans blastospores into invasive forms.
After a single oral administration of the drug at a dosage of 200 mg during a meal, the highest plasma is observed after 1-2 hours.
The degree of binding to plasma proteins is 99%. The remaining small part of the drug enters the cerebrospinal fluid.
After absorption from the gastrointestinal tract, the active substance of the drug is biotransformed, resulting in the formation of inactive metabolites .
Excretion from the body is carried out in two phases: during the first 10 hours, the half-life is 2 hours, in the second phase – 8 hours. Approximately 13% of the drug is excreted in the urine, of which 2-4% is unchanged. It is excreted primarily through the intestines with bile.
Reviews about Mycozoral
Reviews about Mycozoral are mostly positive. Patients note its effectiveness in all forms of release. It helps even in cases where other drugs fail.
However, people who have taken the pills sometimes note that the therapy is quite painful. During the treatment process, the manifestations of the disease could not only not go away, but also intensify.
Reviews of Mycozoral ointment, on the contrary, characterize it as a quick-acting remedy. The effect becomes noticeable from the very first days of use.
In turn, reviews of Mycozoral shampoo from patients and doctors characterize this product as a good analogue of more expensive products for dandruff , mycoses and dermatitis . It's rare that this shampoo isn't suitable for anyone. And the affordable price is another plus.
