Pharmacodynamics and pharmacokinetics
the alkaloids it contains, stimulates the respiratory centers and enhances the secretion of mucus in the bronchioles due to the reflex action on their specific receptors. After taking Thermopsol cough tablets, phlegm . The drug stimulates the vomiting center and therefore in high concentrations can cause vomiting, irritate the stomach, and increase the secretion of gastric juice. The drug also has a weak anti-inflammatory effect, increasing the tone of the vascular endothelium.
Sodium bicarbonate, which is part of the drug , neutralizes increased acidity, thereby protecting the stomach from hypersecretion of hydrochloric acid and damage to the mucous membrane. , the acid-base balance of bronchial mucus shifts , sputum becomes even more diluted and its passage through the respiratory tract is greatly facilitated.
After taking the medicine, the tablets reach their maximum effect after 60 minutes, the duration of the drug’s effect is up to 6 hours.
Composition and dosage form
The main active ingredient of the drug Thermopsol: powder of the medicinal plant thermopsis of the legume family. It contains a complex of alkaloids that irritate the functional cells of the mucosa and stimulate secretion. Thanks to it, the volume of sputum in the lumen of the bronchi increases, its viscosity decreases, and mucus comes out more easily. Another active compound of the drug: sodium bicarbonate. Soda reduces acidity, has a softening and moderate disinfectant effect.
Thermopsol is produced in the form of tablets: without shells, flat-cylindrical in shape, gray-green herbaceous color with small inclusions. One pill of the drug contains 6.7 g of herbal powder and 250 mg. sodium bicarbonate. They are packed in blister packs of 10 pieces. A cardboard package of the product contains 1–3 plates.
Contraindications
The medicine should not be prescribed:
- if allergic to its components (thermopsis, soda) or legumes;
- patients with a stomach ulcer (including a history);
- persons suffering from duodenal ulcer (including a history of it).
Hypertensive patients should take the drug with extreme caution; taking tablets can lead to increased vasoconstriction and increased blood pressure.
How to take Thermopsol
The drug does not contain hazardous chemical components and is low-toxic, so the maximum daily dosage can reach 30 pills or more, depending on the intensity of sputum production. But it is recommended to start therapy with a small dose: take 1–2 pieces. three times a day.
It is not advisable to drink Thermopsol on an empty stomach, so as not to provoke nausea. Best time: 15–30 minutes after eating. The tablets can be swallowed whole or chewed with plain water. You cannot use tea, coffee, sour, sweet and carbonated drinks for this purpose.
Thermopsol can be given to children for coughs and bronchitis if its components are well tolerated. The total course of treatment should not exceed 10 days. At the initial stage of the disease, taking tablets for 3–5 days is enough. When using the drug, it should be taken into account that Thermopsol works worse with the simultaneous use of antacids. It is not compatible with codeine-based cough medicines.
Analogs
Level 4 ATC code matches: Cashnol
Anise oil
Bronchophyte
Pine buds
Pertussin
Bronchosan
Gedelix
Mixture for inhalation
Herbion ivy syrup
Herbion plantain syrup
Herbion primrose syrup
Mukaltin
Sinupret Forte
Dr. Theiss syrup with plantain
Bronchosept
Joset
Tussamag
Marshmallow syrup
Dry cough syrup
Ammonia-anise drops
extracts of marshmallow, anise, oregano, licorice, wild rosemary, eucalyptus, plantain and thyme are closest to the effect of the drug .
Thermopsol tab No. 10
Compound
Thermopsis lanceolata herb + Sodium bicarbonate.
Pharmacokinetics
Thermopsis herb, thanks to the alkaloids it contains, excites the respiratory centers and enhances the secretion of mucus in the bronchioles due to the reflex action on their specific receptors. After taking cough tablets Thermopsol, sputum comes out better. The drug stimulates the vomiting center and therefore in high concentrations can cause vomiting, irritate the stomach, and increase the secretion of gastric juice. The drug also has a weak anti-inflammatory effect, increasing the tone of the vascular endothelium. Sodium bicarbonate, which is part of the drug, neutralizes increased acidity, thereby protecting the stomach from hypersecretion of hydrochloric acid and damage to the mucous membrane. Additionally, the acid-base balance of the bronchial mucus shifts, the sputum becomes even more diluted and its passage through the respiratory tract is greatly facilitated.
Indications for use
The drug is prescribed as part of complex therapy for tracheitis or bronchitis to improve sputum separation.
Contraindications
- if you are allergic to its components (thermopsis, soda) or legumes;
- patients with a stomach ulcer (including a history);
- persons suffering from duodenal ulcer (including a history);
- Hypertensive patients should take the drug with extreme caution; taking tablets can lead to increased vasoconstriction and increased blood pressure.
Directions for use and doses
Adults: 3 tablets per day, in 3 divided doses.
The duration of treatment is from 3 to 5 days.
The maximum single dose is 14 pieces, the daily dose is 42 tablets.
For children, smaller dosages are used in accordance with the doctor's recommendations.
Storage conditions
It is recommended to store the drug away from children, in a cool, dry place.
Best before date
4 years
special instructions
During treatment, warm, abundant warm drinks are indicated, this will enhance the effectiveness of the drug.
The medicine should not be prescribed to patients who are unable to independently expectorate sputum (young children, people with specific diseases).
Description
Thermopsol is a combination drug. It contains powder made from thermopsis grass, as well as sodium bicarbonate. These are the active ingredients that cause the effect of the drug.
Dosage form
The medicine is produced in the form of swamp-green, light, round tablets, in a blister of 10 pieces per package.
Use in children
For children, smaller dosages are used in accordance with the doctor's recommendations.
- Children under 3 years of age
are allowed to take no more than a quarter of a tablet at a time. The frequency of use is the same as for adults - 2-3 times a day. - For children under 6 years of age,
the dose of the medicine can be increased. Depending on the condition and severity of the disease, the doctor may recommend taking a quarter or half of a tablet three times a day. You need to drink the medicine before meals, without chewing. - At 6 years of age and older,
it is recommended to take half or a whole tablet. It is also recommended to take the drug three times - morning, lunch and evening.
Action
Expectorant, anti-inflammatory.
Pharmacodynamics
After taking the medicine, the tablets reach their maximum effect after 60 minutes, the duration of the drug’s effect is up to 6 hours.
Side effects
Rarely, Thermopsol causes allergic reactions, most often of a local nature. When taking large doses, treatment with the drug may be accompanied by nausea and even vomiting.
Use during pregnancy and breastfeeding
According to the instructions for use of cough tablets Thermopsol, the use of this drug during pregnancy and lactation is prohibited. Despite numerous positive reviews, the medicine in such patients can lead to the development of severe undesirable consequences for both mother and child.
Interaction
Thermopsol cough tablets are antagonists of codeine-containing drugs.
When the drug is combined with absorbents, astringents and enveloping agents, the intensity of absorption of Thermopsol in the gastrointestinal tract is reduced.
Other cough medications may reduce the effectiveness of the medicine.
Overdose
There is no evidence of drug overdose. When taking doses significantly higher than the maximum permissible, severe nausea and vomiting may develop. Enterosorbents and symptomatic therapy are indicated.
Impact on the ability to drive vehicles and operate machinery
The use of the drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Reviews of Thermopsol
Reviews about the tablets are good. Due to their availability in any pharmacy and relatively low cost, many use them to treat coughs, often replacing more expensive analogues with this remedy.
Reviews about Thermopsol:
- “... In winter I often catch a cold. When the cold goes away, the dry cough remains. You can, of course, suffer and try to clear your throat until you cry, but I chose a method that has been proven over the years - a remedy based on the herb Thermopsis, cough tablets, the price of which is simply ridiculous”;
- “... I’ve been taking these pills for 8 days, 3 times a day, the cough was strong, in attacks, with sputum difficult to separate, and remains the same. I’ve been suffering for 2 weeks.”
Mechanism of action of Thermopsol
Alkaloids and other active plant substances stimulate the activity of the secretory glands: they help increase the secretion of gastric juice and mucus. The drug stimulates the work of the ciliated epithelium, helps to liquefy sputum clots and remove them. Thermopsis has an anti-inflammatory effect, reduces swelling, burning and other pathological reactions of the respiratory tract during infectious lesions, and increases the tone of the vascular endothelium. As a result of taking the drug, the cough reflex is strengthened, which further accelerates the passage of accumulated mucus clots.
Sodium bicarbonate - baking soda, shifts the balance to the alkaline side, promoting the death of pathogenic microbes on the surface of the mucous membranes. By reducing acidity, it protects the lining of the stomach from excess hydrochloric acid, reduces painful symptoms of the disease, and reduces the risk of belching and heartburn.
The effect of the drug develops after 1–1.5 hours and lasts up to 6–8 hours. After taking the first dose, the cough becomes more productive, and the breaks between attacks become longer. As you take the tablets, the feeling of congestion in the bronchi and lungs decreases. A dry cough caused by difficult-to-discharge sputum becomes less painful and turns into a wet cough.
