Compound
- 1 tablet of Strepsils Plus contains 1.2 mg of dichlorobenzyl alcohol , 10 mg of lidocaine hydrochloride and 600 mcg of amylmetacresol . Additional substances: sodium saccharinate, tartaric acid, levomenthol , anise oil, peppermint oil, quinoline yellow dye, liquid sucrose, indigo carmine , liquid dextrose.
- 1 dose of Strepsils Plus topical spray contains 290 mcg of amylmetacresol , 580 mcg of dichlorobenzyl alcohol and 780 mcg of lidocaine hydrochloride . Additional substances: citric acid, 96% ethanol, carmazine edicol, sodium hydroxide, glycerol, saccharin, levomenthol, sorbitol 70%, anise oil, peppermint oil, water, hydrochloric acid.
Strepsils Plus tablets d/rassas No. 12
Compound
One lozenge contains:
active substances:
2,4-dichlorobenzyl alcohol 1.2 mg, amylmetacresol 0.6 mg, lidocaine hydrochloride monohydrate 10 mg,
Excipients:
tartaric acid 26 mg, sodium saccharinate 2.08 mg, levomenthol 2.08 mg, peppermint leaf oil 2.08 mg, anise seed oil 0.52 mg, quinoline yellow dye 0.0046 mg, indigo carmine 0.0156 mg, liquid sucrose 1523.4 mg, liquid dextrose, oligo- and polysaccharides 980.9 mg.
Indications for use
Symptomatic treatment of pain in the mouth, throat, larynx due to infectious inflammatory diseases: tonsillitis, pharyngitis, laryngitis (including those of a professional nature - in teachers, announcers, workers in the chemical and coal industries), hoarseness, inflammation of the oral mucosa and gums ( aphthous stomatitis, gingivitis, thrush).
Contraindications
Although unlikely, overdose may result in anesthesia of the upper gastrointestinal tract.
Treatment:
symptomatic.
Directions for use and doses
Locally.
Adults and children over 12 years old
- dissolve 1 tablet every 2-3 hours.
Do not use more than 8 tablets within 24 hours.
Duration of use - no more than 5 days.
Storage conditions
In a dry place, at a temperature not exceeding 25 C.
Keep out of the reach of children.
Best before date
3 years.
Do not use a drug that has expired.
special instructions
If there is a possible loss of tongue sensitivity, it is recommended to be careful when consuming hot food and water.
You should not use the drug if you have increased individual sensitivity to any component included in the drug.
When prescribing to patients with diabetes, it is necessary to take into account that 1 tablet contains 2.6 g of sugar.
Description
Flat-cylindrical tablets of bluish-green color with the image of the letter S on both sides of the tablet, with the smell of menthol. The presence of a white coating, minor air bubbles inside the caramel mass and uneven edges is allowed.
Conditions for dispensing from pharmacies
Over the counter
Dosage form
lozenges
Pharmacodynamics
The drug has an antiseptic effect, is active against gram-positive and gram-negative microorganisms, and has an antimycotic effect. It also has a local anesthetic and anti-edematous effect.
Side effects
Allergic reactions, loss of tongue sensitivity.
Use during pregnancy and breastfeeding
The use of the drug during pregnancy and lactation is possible only under the supervision of a doctor.
Interaction
No clinically significant interactions with other drugs have been recorded.
Overdose
Although unlikely, overdose may result in anesthesia of the upper gastrointestinal tract.
Treatment:
symptomatic.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Multicomponent antiseptic drug for local use in ENT pathology and dentistry. Has antimicrobial and local analgesic effects. Demonstrates activity against many gram-positive and gram-negative microorganisms in the laboratory, and also has an antifungal effect.
Natural medicinal additives in the composition of the drug have a softening effect on inflammatory mucous membranes.
Pharmacokinetics
Due to negligible absorption into the systemic circulation, pharmacokinetic data are not provided.
Strepsils Express throat spray 20ml
Compound
Active ingredients: 2,4-dichlorobenzyl alcohol 580 mcg, amylmetacresol 290 mcg, lidocaine hydrochloride 780 mcg. Excipients: ethanol 96% - 52 µl, citric acid - 0.19 mg, glycerol - 13 µl, sorbitol solution 70% (non-crystallized) - 13 µl, saccharin - 0.026 mg, levomenthol - 0.104 mg, peppermint leaf oil - 0.156 µl, anise seed oil - 0.065 µl, azorubine (karmazin edikol) - 0.008 mg, purified water - up to 130 µl, sodium hydroxide - qs, concentrated hydrochloric acid - qs
Indications for use
Symptomatic treatment of severe sore throat in infectious and inflammatory diseases.
Contraindications
- Hypersensitivity to the components of the combination;
- indications in the anamnesis of allergies to local anesthetics;
- indications in anamnesis or tendency to methemoglobinemia;
- bronchial asthma, bronchospasm;
- children's age up to 12 years.
With caution: pregnancy, breastfeeding, trauma to the oral mucosa.
Directions for use and doses
Apply topically every 2 hours, no more than 8 times within 24 hours.
Do not exceed the indicated dose.
The duration of treatment is no more than 3 days. If symptoms persist after using the drug in the appropriate dosage form for 3 days, the patient should stop treatment and consult a doctor.
Storage conditions
Store at a temperature not exceeding 30 °C. Keep out of the reach of children.
special instructions
It is recommended to take the drug for the shortest possible course and in the minimum effective dose necessary to eliminate symptoms.
If there is a possible loss of sensitivity in the tongue, it is recommended to be careful when eating hot food and water; biting the tongue and lips is possible.
If symptoms persist or if body temperature rises or headaches occur, the patient should consult a doctor.
Description
A drug with antimicrobial and local anesthetic effects for local use in ENT practice and dentistry.
Action
Combined antiseptic drug.
The combination is active against gram-positive and gram-negative microorganisms in vitro; has an antifungal effect.
It also has a local anesthetic and anti-edematous effect.
Side effects
From the immune system: frequency unknown - hypersensitivity reactions (including angioedema, urticaria).
From the cardiovascular system: arterial hypotension with fainting.
From the digestive system: frequency unknown - nausea, burning or tingling sensation, swelling in the mouth.
From the skin and subcutaneous tissues: frequency unknown - rash.
Use during pregnancy and breastfeeding
The use of the drug during pregnancy and breastfeeding is possible only on the recommendation of a doctor if the expected benefit to the mother outweighs the potential risk to the fetus and child.
Interaction
The effect of topically applied lidocaine may be enhanced when used simultaneously with erythromycin, itraconazole, cimetidine, fluvoxamine, beta-blockers, and other antiarrhythmic drugs, for example, mexiletine.
Impact on the ability to drive vehicles and operate machinery
The drug does not affect the ability to drive vehicles and machinery, as well as to engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Instructions for use Strepsils Plus (Method and dosage)
Strepsils Plus tablets, instructions for use
The tablets are intended to be dissolved and should not be swallowed or bitten.
Adults and children over 12 years of age are recommended to suck on 1 lozenge every two hours, but it is forbidden to take more than 8 pieces per day. The tablets need to be dissolved in the mouth until they are completely dissolved.
Spray Strepsils Plus, instructions for use
Strepsils Plus spray is prescribed only to patients over 12 years of age. Every 3 hours, spray 1 dose (which corresponds to 2 presses) in the area of the inflamed area. It is prohibited to use more than 6 doses per day. The duration of treatment should not be more than 5 days.
Strepsils Intensive Spray, 15 ml, 8.75 mg/dose, for topical use
Interaction with other drugs
The simultaneous use of the drug with the following drugs should be avoided: • Acetylsalicylic acid: with the exception of low doses of acetylsalicylic acid (no more than 75 mg per day) prescribed by a doctor, since combined use may increase the risk of side effects. • Other NSAIDs, including ibuprofen and selective cyclooxygenase-2 inhibitors: Concomitant use of two or more NSAIDs should be avoided due to a possible increased risk of side effects. Use with caution simultaneously with the following drugs: • Anticoagulants: NSAIDs may enhance the effects of anticoagulants, including warfarin. • Antiplatelet agents and selective serotonin reuptake inhibitors: increased risk of gastrointestinal bleeding. • Antihypertensives (ACE inhibitors and angiotensin II antagonists) and diuretics: NSAIDs may reduce the effectiveness of these drugs and may increase nephrotoxicity due to cyclooxygenase inhibition, especially in patients with impaired renal function (it is necessary to ensure adequate fluid replacement in such patients). • Ethanol: may increase the risk of adverse reactions, especially gastrointestinal bleeding. • Cardiac glycosides: simultaneous use of NSAIDs and cardiac glycosides can lead to worsening heart failure, a decrease in glomerular filtration rate and an increase in the concentration of cardiac glycosides in the blood plasma. • Cyclosporine: increased risk of nephrotoxicity. • Glucocorticosteroids: increased risk of gastrointestinal ulceration and gastrointestinal bleeding. • Lithium preparations: there is evidence of the likelihood of an increase in the concentration of lithium in the blood plasma during the use of NSAIDs. • Methotrexate: there is evidence of the likelihood of an increase in the concentration of methotrexate in the blood plasma during the use of NSAIDs. It is necessary to take NSAIDs 24 hours before or after taking methotrexate. • Mifepristone: NSAIDs should be started no earlier than 8-12 days after stopping mifepristone, as NSAIDs may reduce the effectiveness of mifepristone. • Quinolone antibiotics: Patients receiving concomitant treatment with NSAIDs and quinolone antibiotics may have an increased risk of seizures. • Tacrolimus: when used together with NSAIDs, there may be an increased risk of nephrotoxicity. • Zidovudine: when used together with NSAIDs, there may be an increased risk of hematotoxicity. m • Oral hypoglycemic drugs: possible changes in blood glucose concentrations (it is recommended to increase the frequency of monitoring blood glucose concentrations). • Phenytoin: an increase in the concentration of phenytoin in the blood serum is possible (monitoring the concentration of phenytoin in the blood serum and, if necessary, dose adjustment is recommended). • Potassium-sparing diuretics: Concomitant use of potassium-sparing diuretics and flurbiprofen may lead to hyperkalemia. • Probenecid and sulfinpyrazone: Medicines containing probenecid or sulfinpyrazone may delay the elimination of flurbiprofen. • Tolbutamide and antacids: To date, studies have shown no interactions between flurbiprofen and tolbutamide or antacids.
Analogs
Level 4 ATC code matches: Falimint
Suprima-ENT
Ingalipt-N
Strepsils
Ingalipt
TheraFlu LAR
Hexoral Tabs
Lisak
Efizol
Angilex
Kameton
Anzibel
Agisept
Yox
Lugol's solution with glycerin
Lugol
Laripront
Stopangin 2A
Stopangin
Septolete Neo
Rinza Lorsept Anesthetics , Hexoral Tabs extra .
Side effects
The following adverse reactions have been observed during short-term use of over-the-counter doses of 2,4-dichlorobenzyl alcohol, amylmetacresol, and lidocaine. In case of long-term treatment of chronic conditions, additional side effects may occur. When treating chronic diseases, additional side effects may occur with long-term use.
Adverse reactions that occurred with the use of 2,4-dichlorobenzyl alcohol, amylmetacresol and lidocaine are listed by organ system and the frequency of their occurrence. Frequency of adverse reactions: frequency unknown (cannot be estimated based on available data).
Immune system: unknown - hypersensitivity, anaphylactic reactions, allergic reactions, including rash, burning sensation in the mouth or throat and swelling of the mouth and throat, urticaria, angioedema.
From the skin and subcutaneous tissue: unknown - rash, itching.
From the gastrointestinal tract: unknown - nausea, oral discomfort, abdominal pain, stomatitis, dyspepsia, heartburn.
From the nervous system: unknown - dysgeusia.
Price, where to buy
The price of Strepsils Plus spray in Russia is 450-480 rubles, while a package of tablets No. 24 of the same name costs approximately 350-405 rubles.
In Ukraine, the spray can be purchased for 90-107 hryvnia, and the above package of tablets for about 73-85 hryvnia.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
Pharmacy Dialogue
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PaniPharmacy
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