Gistan-N, 0.1%, cream for external use, 15 g, 1 pc.


Compound

Each capsule contains dry extracts of tripartite, chamomile and immortelle. Additionally, the medication contains vitamins ( B5 , B12 , E , A ) and quercetin .
Gistan cream contains the following extracts:

  • tricolor violet;
  • Birch buds;
  • calendula flowers;
  • dropsy herb;
  • milkweed grass;
  • spiky veronica.

Additionally, Gistan ointment contains dimethicone , lily of the valley oil, betulin and the peptide form of lupine extract.

pharmachologic effect

Gistan cream is a parapharmaceutical that is used exclusively externally for various skin rashes of allergic origin:

  • blistering, vesicular rashes;
  • hives;
  • itchy skin.

The basis of the cream was a hypoallergenic base containing a natural antihistamine substance betulin , isolated from thin birch bark. The medication does not contain hormonal components.

The hypoallergenic base is based on dimethicone , which is a silicone polyglucoside , thanks to which a protective film is created on the affected skin. The special properties of Dimethicone make it possible to limit the flow of allergens and moisture to the skin, but free access to oxygen is provided.

Additionally, the ointment contains essential lily of the valley oil and herbal extracts with antiallergic effects. Easy penetration of essential lily of the valley oil into the skin is ensured by its molecular structure. As a result, blood circulation increases and metabolic processes .

The complex antiseptic effect of herbal extracts and lily of the valley oil helps prevent the development of infectious skin lesions during allergic responses . A persistent therapeutic effect in pediatric practice is observed 3 weeks after daily applications in children over two years of age.

The capsules are a dietary supplement - a source of arbutin , flavonoids and glycyrrhizic acid . The complex effect of active components makes it possible to normalize the functional state of human organs and tissues susceptible to allergic responses. The dietary supplement can also be used for preventive purposes. The capsules contain plant derivatives that are used in traditional healing medicine.

Gistan cream external 30 ml x1

Composition | Gistan cream 30ml. Water, stearitin, dimethicone, cyclormethicone, MHD, MFT, extracts: birch buds, speedwell, milkweed herb, string of tripartite, tricolor violet, dropsy herb, calendula flowers, lupine peptide extract, betulin, lily of the valley oil, citric acid, CG cathode. Manufacturer | Gistan cream 30ml. LLC "VIS" Russia, 198020, Obvodny Canal embankment, 223-225.

Indications for use | Gistan cream 30ml. GMSTAN cream is an effective and safe non-hormonal external remedy used for allergic rashes on the skin of the face, hands and body, for skin itching, urticaria, vesicular (bubble) allergic manifestations on the skin. GISTAN is effective against insect bites, it quickly eliminates itching and blisters. For allergic skin rashes caused by exposure to sunlight. GISTAN is indicated for drug allergies (skin manifestations), as it is used as an external remedy, especially when oral administration of antihistamines is contraindicated. GISTAN is recommended for use in cases where discontinuation of corticosteroid ointments is impossible - to prevent the development of infectious complications.

Contraindications | Gistan cream 30ml. Individual intolerance to product components.

Description | Gistan cream 30ml. GISTAN cream is prepared on the basis of a hypoallergenic base with the addition of a unique natural antihistamine Betulin, obtained from thin birch bark. The main component of the hypoallergenic base, dimethicone, is famous for its softness and does not cause irritation. Dimethicone is a silicone polyglucoside. Which creates an invisible film on the affected areas of the skin, freely allowing oxygen to pass to the skin and preventing moisture and allergens, which is especially important for contact dermatitis. The cream also contains extracts of antiallergic herbs and lily of the valley essential oil. The molecular structure of lily of the valley essential hypoallergenic oil facilitates its easy penetration into the skin, resulting in stimulation and improvement of metabolic processes, blood circulation and removal of waste and toxins from the skin. Lily of the valley oil and herbal extracts help prevent infectious complications in allergic skin lesions due to their antiseptic and antiviral properties.

Storage life and conditions | Gistan cream 30ml. Store at temperatures from +5 to +25 C out of the reach of children. Shelf life: 24 months.

Indications for use

The cream is used as a non-hormonal remedy in the fight against skin itching and rashes in the following conditions:

  • photodermatosis;
  • neurodermatitis;
  • eczema;
  • insect bites;
  • hives;
  • dosage form of allergy.

The drug can be prescribed for prophylactic purposes to prevent infectious complications during treatment with corticosteroid ointments and agents.

The capsule form is used as an auxiliary source of vitamins and flavonoids .

Indications

  • Allergic rashes on the skin of the face, hands and body;
  • Skin itching, urticaria;
  • Vesicular (bubble) allergic manifestations on the skin;
  • Insect bites;
  • Psoriasis, eczema, neurodermatitis (as a symptomatic remedy);
  • Phlebatoderma;
  • Toxicoderma;
  • Photodermatitis (when exposed to sunlight);
  • Cases when discontinuation of corticosteroid ointments is impossible - to prevent the development of infectious diseases.

Side effects

Negative local reactions when using the cream:

  • hypopigmentation;
  • burning;
  • addition of a secondary infection;
  • maceration of the skin;
  • prickly heat;
  • perioral dermatitis;
  • folliculitis;
  • paresthesia;
  • atrophy of the skin;
  • acne;
  • striae;
  • contact dermatitis of allergic origin;
  • hypertrichosis.

Allergic responses are possible when taking capsules.

Instructions for use of Gistan (Method and dosage)

The cream is used only externally, and the capsules are used per os.

Gistan cream, instructions for use

Apply a thin layer of ointment to the affected areas of the skin once a day. The course of therapy is designed for 7-28 days and depends on the effectiveness of the treatment and the patient’s tolerability of the drug.

Gistan capsules, instructions for use

The course is designed for 20 days of daily use, 1 capsule (children over 14 years old and adult patients). A repeated course can be carried out only after a 10-day break. Repeated appointments are possible throughout the year.

Gistan-N, 0.1%, cream for external use, 15 g, 1 pc.

GISTAN-N CREAM FOR EXTERNAL USE 0.1% 15.0

INSTRUCTIONS for medical use of the drug
Registration number: LSR-008698/10

International nonproprietary name: Mometasone

Dosage form: cream for external use

Compound:

Active ingredient: mometasone furoate.

Excipients: liquid paraffin, soft white paraffin, propylene glycol, emulsion wax, sodium citrate, chlorocresol, cetomacrogol, water.

Description:

White homogeneous cream

Pharmacotherapeutic group:

Glucocorticosteroid for local use

Pharmacological properties:

Mometasone is a synthetic glucocorticosteroid (GCS). It has anti-inflammatory, antipruritic and antiexudative effects. GCS induces the release of proteins that inhibit phospholipase A2 and are known collectively as lipocortins, which control the biosynthesis of inflammatory mediators such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid.

Prevents the marginal accumulation of neutrophils, which reduces inflammatory exudate and cytokine production, inhibits the migration of macrophages, and leads to a decrease in the processes of infiltration and granulation. Reduces inflammation by reducing the formation of a chemotaxis substance (impact on “late” allergy reactions), inhibits the development of an “immediate” allergic reaction (due to inhibition of the production of arachidonic acid metabolites and a decrease in the release of inflammatory mediators from mast cells).

With daily application of the cream to children over 2 years of age with allergic dermatitis, the therapeutic effect appears within 3 weeks.

Pharmacokinetics:

Absorption of Gistan-N cream is low. 8 hours after application to intact skin (without an occlusive dressing), about 0.4% of the dose is found in the systemic circulation. With inflammation and damage to the skin, absorption increases.

Indications for use:

Inflammation and itching of the skin in dermatoses (including psoriasis, atopic dermatitis, seborrheic dermatitis), for which GCS therapy is indicated.

Contraindications:

  • Hypersensitivity to any component of the drug or to other corticosteroids.
  • Rosacea, perioral dermatitis.
  • Bacterial, viral (Herpes simplex, chickenpox, Herpes zoster) or fungal skin infection.
  • Tuberculosis, syphilis.
  • Post-vaccination reactions.
  • Pregnancy (treatment of large areas of skin, long-term treatment).
  • Lactation period (use in large doses and/or for a long time).
  • Children under 2 years of age.

Carefully:

Application to the facial skin and intertriginous skin surface, use of occlusive dressings, as well as treatment of large areas of skin and/or long-term treatment (especially in children).

Use during pregnancy and lactation:

The safety of mometasone furoate during pregnancy and lactation has not been studied.

GCS penetrates the placental barrier. Long-term treatment and the use of large doses during pregnancy should be avoided due to the risk of negative effects on fetal development.

GCS are excreted in breast milk. In cases where GCS is intended to be used in large doses and/or for a long time, breastfeeding should be stopped.

Directions for use and dosage:

Externally.

A thin layer of the drug is applied to the affected areas of the skin once a day.

Duration of treatment: 7–28 days, determined by the effectiveness of therapy, as well as the patient’s tolerability of the drug, the presence and severity of side effects.

Side effects:

Local reactions: burning, itching, paresthesia, folliculitis, acne, skin atrophy, hypertrichosis, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infection, striae, prickly heat.

The likelihood of these adverse events occurring increases with the use of occlusive dressings.

Systemic action: when using external forms of GCS for a long time and/or for treating large areas of skin (the total area of ​​application is greater than the area of ​​the patient's palm), or using occlusive dressings, especially in children and adolescents, side effects characteristic of GCS may occur systemic action, including adrenal insufficiency and Itsenko-Cushing syndrome.

Overdose:

Symptoms: inhibition of the functions of the hypothalamic-pituitary-adrenal system (including secondary adrenal insufficiency).

Treatment: symptomatic. If necessary, correct the electrolyte balance, discontinue the drug (for long-term therapy, gradual withdrawal).

Interaction with other drugs:

Not found.

Special instructions:

If there is no effect within 2 weeks of drug therapy, the diagnosis should be clarified.

When applied to large areas of skin for a long time, especially when using occlusive dressings, systemic action of GCS may develop. Given this, it is necessary to monitor the function of the hypothalamic-pituitary-adrenal system.

Avoid contact of the drug with the eyes.

Propylene glycol contained in the composition may cause irritation at the site of application. In such cases, use of the drug should be discontinued and appropriate treatment should be prescribed.

It should be borne in mind that GCS can change the manifestation of some skin diseases, which can complicate the diagnosis. In addition, the use of GCS may cause a delay in wound healing.

With long-term therapy with GCS, sudden cessation of therapy can lead to the development of rebound syndrome, manifested in the form of dermatitis with intense redness of the skin and a burning sensation. Therefore, after a long course of treatment, drug withdrawal should be carried out gradually, for example, by switching to an intermittent treatment regimen before stopping it completely.

Application in pediatrics:

Due to the fact that in children the ratio of surface area to body weight is greater than in adults, children are at greater risk of suppressing the function of the hypothalamic-pituitary-adrenal system and developing Cushing's syndrome when using any topical corticosteroids. Long-term treatment of children with GCS can lead to disruption of their growth and development. The use of the drug in children for more than 3 weeks has not been studied.

Children should receive the minimum dose of the drug sufficient to achieve the effect.

Release form:

cream for external use 0.1%.

15 g of the drug in an aluminum tube.

1 tube in a cardboard box along with instructions for use.

Storage conditions:

At a temperature not exceeding 25°C.

Do not freeze.

Keep out of the reach of children.

Shelf life – 3 years. Do not use after expiration date.

Conditions for dispensing from pharmacies: by prescription.

Reviews about Gistan

Reviews about Gistan cream are mostly positive: a relatively inexpensive, but at the same time very effective remedy for the treatment of allergic skin rashes that does not contain hormonal components. The herbal composition adds to the attractiveness of Gistan for patients. The only downside that can be noted is the long waiting period before the onset of the therapeutic effect of the medication, which is again explained by the herbal composition of the cream.

The capsules are easy to use (one-time daily dose), do not cause significant negative symptoms, and help quickly relieve allergic responses. The limit for children is reaching the age of 14.

Action

  • Antihistamine;
  • Anti-inflammatory;
  • Antipruritic;
  • Antibacterial;
  • Antiviral;
  • Antiseptic;
  • Improving skin metabolic processes.

Gistan cream is a one-of-a-kind product containing the most powerful natural antiallergic substances. Lily of the valley oil, which is part of Gistan, is the best natural antihistamine.

Extracts of string, violet and calendula flowers have an anti-inflammatory effect.

Birch buds and euphorbia give Gistan cream an antipruritic effect. A special substance - dimethicone - makes the absorption of the cream as fast and complete as possible.

Gistan cream is an effective and safe non-hormonal external remedy. Gistan is a real salvation for everyone who is susceptible to any skin allergic manifestations. Allergic rashes on the skin of the face, hands and body, hives, itching are no longer a problem if you use Gistan . The cream can be used as a natural remedy that relieves symptoms of psoriasis and eczema of various origins. Gistan has been proven to be highly effective against insect bites - the cream quickly, literally before your eyes, eliminates blisters and relieves itching.

Gistan cream is:

  • effective, easy-to-use external remedy;
  • non-hormonal and therefore absolutely safe drug;
  • a product with a complex antiallergic, antipruritic and anti-inflammatory effect.

Gistane is easily absorbed and acts quickly. Effective for eliminating itching and inflammation in psoriasis, neurodermatitis, eczema.

Gistan price, where to buy

The cost of a herbal medicine depends on the form of release and the pharmacy chain. The average price of Gistan cream in Russia is 200 rubles per tube of 30 g. Ointment 15 g will cost about 150 rubles. The price of tablets (capsules) is 190 rubles.

  • Online pharmacies in RussiaRussia
  • Online pharmacies in KazakhstanKazakhstan

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