Compound
1 tablet contains: long-leaved astercanth seeds - 19 mg, compass lettuce seeds in powder form and dry pearl parmelia thallus extract 10 mg each, male orchis tubers - 39 mg, mosaic gold (tin disulfide) and velvet itchy bean seed powder - 10 mg each mg, extract of the roots of beautiful argyrea, creeping Tribulus fruits and stems of reticulate leptadenia - 19 mg each, roots of snake rauwolfia in the form of a dry extract - 18.75 mg.
The tablet contains the following excipients: carmellose sodium, microcrystalline cellulose, crospovidone, silicon dioxide, magnesium stearate.
Analogs
Level 4 ATX code matches: Renel
Samprost
Lingonberry leaves
Uriflorin
Gentos
Bioprost
Bearberry leaves
Testis compositum
Birch buds
Lespefril
Prostopin
Lespeflan
Phytonephrol
Lespenefril
Canephron N
Vitaprost Forte
Vitaprost Plus
Vitaprost
Brusniver
Speman
There are many analogues with different active ingredients: Speman , Vezilut , Viagra, Vigrande , Vuka Vuka , Impaza , Cialis , Tentex Forte , Veromax , Levitra , Sealex .
Drug interactions and special instructions
If a pathology such as oligospermia is detected, doctors recommend the simultaneous use of Tentex Forte and Speman. This significantly increases the effectiveness of the treatment used.
Additional intake of vitamin E can help increase blood pressure, increase serum triglycerides, and reduce the need for insulin in insulin-dependent diabetes. Therefore, it is necessary to regularly monitor blood sugar.
Speman should be prescribed with caution if the patient has certain disorders.
Such pathologies are:
- Myocardial infarction.
- Severe cardiosclerosis.
- Increased risk of thromboembolism.
- Signs of hypervitaminosis.
If the patient takes additional vitamin E, he may experience nausea and some other dyspeptic symptoms.
Taking the drug together with alcohol has a negative effect on the body and reduces the therapeutic effectiveness of the drug.
Reviews of Speman Forte
Available reviews from doctors about the drug indicate an ambiguous attitude of official medicine towards the use of the drug. Some doctors consider it a good remedy for treating reduced potency , especially against the background of prostatitis , since when taken it improves blood circulation and reduces stagnation in the prostate. Another part of doctors prescribe medicine, but only as part of a complex treatment, as an auxiliary drug. There is also an opinion that you can do without this medicine, since there is no reliable evidence of its effectiveness.
Numerous reviews of Speman Forte from men who have experience in its use indicate that the drug is quite effective for the treatment of premature ejaculation , since it prolongs sexual intercourse.
Also, everyone points to the safety of the drug, since it is made from natural herbal raw materials.
Ibufen Forte suspension for oral administration 200 mg/5 ml 100 ml No. 1
Name
Ibufen forte.
Release form
Suspension for oral administration.
Dosage
200 mg / 5 ml 100 ml. Packing quantity: 1 pc.
Manufacturer
Medana Pharma S.A.
INN
Ibuprofen.
FTG
Npvp.
Compound
5 ml of suspension contain: active ingredient: ibuprofen 200 mg excipients: macrogol glyceryl hydroxystearate, xanthan gum, glycerol, sodium benzoate, sodium phosphate dodecahydrate (or dihydrate), citric acid monohydrate, sodium saccharinate, liquid maltitol, Cola flavoring, purified water .
Pharmacotherapeutic group
Nonsteroidal anti-inflammatory and antirheumatic drugs. Propionic acid derivatives. ATS code: M01AE01
Pharmacological properties
Ibuprofen is a propionic acid derivative. It has analgesic, antipyretic and anti-inflammatory effects. The mechanism of action of ibuprofen is primarily due to the suppression of prostaglandin biosynthesis by reducing the activity of cyclooxygenase (COX), an enzyme that regulates the conversion of arachidonic acid into prostaglandins, prostacyclin and thromboxane. At the same time, as a result of irreversible inhibition of the cyclooxygenase pathway of arachidonic acid metabolism, the formation of prostaglandins decreases. A decrease in the concentration of prostaglandins at the site of inflammation is accompanied by a decrease in the formation of bradykinin, endogenous pyrogens, other biologically active substances, oxygen radicals and nitric oxide (II). All this leads to a decrease in the activity of the inflammatory process (anti-inflammatory effect of ibuprofen) and is accompanied by a decrease in pain reception (analgesic effect). A decrease in the concentration of prostaglandins in the cerebrospinal fluid leads to normalization of body temperature (antipyretic effect). After oral administration, more than 80% of ibuprofen is absorbed from the digestive tract. 90% of the drug binds to blood plasma proteins (mainly albumin). The period to achieve maximum concentration in blood plasma when taken on an empty stomach is 45 minutes, when taken after meals - 1.5-2.5 hours; in synovial fluid - 2-3 hours, where higher concentrations are created than in blood plasma. The drug does not accumulate in the body. Ibuprofen is metabolized mainly in the liver. Subject to presystemic and postsystemic metabolism. After absorption, about 60% of the pharmacologically inactive form of ibuprofen is slowly transformed into the active form. 60-90% of the drug is excreted by the kidneys in the form of metabolites and products of their combination with glucuronic acid, to a lesser extent, with bile and no more than 1% is excreted unchanged. After taking a single dose, the drug is completely eliminated within 24 hours.
Indications for use
Ibufen® Forte has antipyretic, analgesic, and anti-inflammatory effects. Reduces symptoms such as fever, pain and swelling by acting at the site of their occurrence. The drug does not contain sugar, so it can be used in people with diabetes. Ibufen® Forte is intended for use in the following cases: Increased body temperature of various origins with: colds, acute respiratory viral infections, influenza, sore throat (pharyngitis), childhood infections accompanied by an increase in body temperature, post-vaccination reactions. Pain syndrome of various origins of weak and moderate intensity with: ear pain with inflammation of the middle ear toothache, painful teething headaches, migraines painful menstruation neuralgia rheumatic pain pain in muscles, joints injuries of the musculoskeletal system.
Contraindications
The drug Ibufen® Forte should not be used in the case of: individual hypersensitivity to any component of the drug, as well as to other non-steroidal anti-inflammatory drugs; any previous manifestations of allergy symptoms in the form of a runny nose, skin rashes or bronchospastic reactions after using acetylsalicylic acid or other non-steroidal anti-inflammatory drugs; peptic ulcer of the stomach and duodenum in the acute phase; severe insufficiency of liver and kidney function; severe heart failure (NYHA class IV); blood diseases: hemophilia, hypocoagulation, hemorrhagic diathesis; in the third trimester of pregnancy.
Interaction with other drugs
Ibuprofen (as well as other drugs from the group of non-steroidal anti-inflammatory drugs) should not be used simultaneously with the following drugs: acetylsalicylic acid; Simultaneous therapy with ibuprofen and acetylsalicylic acid is not recommended due to the possible aggravation of undesirable effects. when used together, increases the hypoglycemic effect of oral antidiabetic agents (sulfonylurea derivatives) and insulin; enhances the side effects of mineralocorticoids, corticosteroids, estrogens, ethanol; when taken simultaneously, antacids and cholestyramine reduce the absorption of ibuprofen; when used together, ibuprofen increases the blood concentration of digoxin, lithium, methotrexate; ibuprofen increases the plasma concentration of cyclosporine and the likelihood of developing its hepatotoxic effects; when used together, inducers of microsomal oxidation (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, increasing the risk of developing severe intoxications; microsomal oxidation inhibitors reduce the risk of developing hepatotoxic effects of ibuprofen; when used together, ibuprofen reduces the hypotensive activity of vasodilators, the natriuretic effect of furosemide and hydrochlorothiazide; when used together, cyclosporine and gold preparations enhance the effects of ibuprofen on prostaglandin synthesis in the kidneys, which leads to an increased nephrotoxic effect; when used simultaneously with anticoagulants and thrombolytic drugs (alteplase, streptokinase, urokinase), the risk of bleeding increases; when used together with ibuprofen, cefamandole, cefoperazine, cefotetan, valproic acid, plicamycin increase the incidence of hypoprothrombinemia; ibuprofen reduces the effectiveness of uricosuric drugs, enhances the effect of indirect anticoagulants, antiplatelet agents, fibrinolytics; drugs that block tubular secretion, when used simultaneously, reduce the excretion and increase the plasma concentration of ibuprofen; caffeine enhances the analgesic effect of ibuprofen.
special instructions
Before taking Ibufen® Forte, you should consult a doctor if the following have been previously confirmed: bronchial asthma, urticaria, liver and kidney diseases, a history of gastric and duodenal ulcers, arterial hypertension. The drug does not contain dyes and can be used in children prone to allergic reactions to dyes in recommended dosages. Taking the drug for as short a period as necessary to relieve symptoms reduces the risk of side effects. Taking anti-inflammatory/pain-relieving medications such as ibuprofen may have a slight increased risk of heart attack or stroke, especially when taken in high doses. Do not exceed the recommended dose and duration of treatment. You should discuss your treatment with your doctor or pharmacist before taking Ibufen® Forte if you: have heart problems, including heart failure, angina (chest pain), or if you have previously had a heart attack, coronary artery surgery blood vessels, any type of stroke (including mini-stroke or transient ischemic attack (TIA)) or have peripheral artery disease (poor circulation in the feet due to narrowing or blockage of the arteries); have high blood pressure, diabetes, high blood cholesterol, heart disease or stroke in your family, or if you smoke. Severe skin reactions, some of them fatal, including scaly dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported very rarely in association with the use of NSAID drugs. The highest risk of these severe reactions occurs at the beginning of therapy, in most cases in the first month of using the drug. It is necessary to stop using the drug after the first symptoms appear: skin rash, changes in the oral mucosa or other symptoms of hypersensitivity. Children and teenagers who are dehydrated are at risk of kidney failure. Isolated cases of toxic amblyopia (decreased visual acuity) have been reported when using ibuprofen, so any visual disturbances should be reported to your doctor. This drug belongs to a group of drugs (nonsteroidal anti-inflammatory drugs) that may adversely affect women's fertility. This is a transient effect and goes away after the end of therapy.
Pregnancy and lactation
The use of ibuprofen in the first 6 months of pregnancy requires caution and is permitted only as prescribed by a doctor, after assessing the expected benefits and possible risks. Ibuprofen should not be used in the last trimester of pregnancy. Ibuprofen may be excreted in breast milk in small quantities. There are no known cases of side effects in infants, but it is recommended to stop breastfeeding during treatment with ibuprofen.
Impact on the ability to drive vehicles and operate mechanical equipment
There is no information on contraindications to driving and servicing machinery after taking Ibufen® Forte.
Directions for use and doses
For oral use. 5 ml of suspension contain 200 mg of ibuprofen. Before use, shake until a homogeneous suspension is obtained. The drug is taken after meals with liquid. The measuring cup with scale included in the package allows you to accurately dose the drug. The dose is set depending on age and body weight. A single dose of Ibufen® Forte is 5-10 mg/kg of the child’s body weight 3-4 times a day. The maximum daily dose of the suspension is 20-30 mg/kg body weight. The drug is prescribed in single doses according to the scheme below: Children from 1 year to 2 years (10-12 kg): a single dose of 2.5 ml (which corresponds to 100 mg of ibuprofen). The maximum daily dose is 7.5 ml (300 mg ibuprofen). Children from 3 to 5 years (13-19 kg): a single dose of 2.5 ml (equivalent to 100 mg of ibuprofen). The maximum daily dose is 10 ml (400 mg ibuprofen). Children from 6 to 9 years (20-29 kg): a single dose of 5.0 ml (equivalent to 200 mg of ibuprofen). The maximum daily dose is 15 ml (600 mg ibuprofen). Children from 10 to 12 years old (30-39 kg): a single dose of 5.0 ml (equivalent to 200 mg of ibuprofen). The maximum daily dose is 20 ml (800 mg ibuprofen). Children from 12 years of age and adults (over 40 kg): a single dose of 5.0-10.0 ml (which corresponds to 200-400 mg of ibuprofen). The maximum daily dose is 30 ml (1200 mg ibuprofen). The minimum interval between subsequent doses is 4-6 hours. Children under 1 year of age can use the drug only after consulting a doctor in accordance with his recommendations. The drug should not be used for more than 3 days without medical supervision. Undesirable effects can be minimized by using the drug for the shortest amount of time necessary at the lowest effective dose to control symptoms.
Overdose
If you take a higher dose of the drug than recommended, you should immediately contact your doctor or pharmacist. Symptoms of overdose: abdominal pain, vomiting, lethargy, headache, tinnitus, depression, drowsiness, metabolic acidosis, coma, hemorrhagic diathesis, decreased blood pressure, convulsions, acute renal failure, liver dysfunction, increased or decreased heart rate. High doses of ibuprofen are usually well tolerated, provided that no other drugs are used at the same time. Measures in case of overdose: gastric lavage (only within an hour after taking the drug), activated charcoal, alkaline drinking, symptomatic therapy (correction of acid-base status, blood pressure).
Side effect
Side effects are classified by frequency of occurrence using the following definitions: - very often: ≥ 1/10 common: ≥ 1/100 to
Best before date
2 years An opened bottle must be used within 6 months. Do not use after the expiration date stated on the package. Dispensed from pharmacies Without a prescription.
Storage conditions
Store in original packaging to protect from light, at temperatures below 25°C. The medicine should be stored out of the reach of children.
Package
100 ml in plastic bottles with a screw cap with a guarantee ring and a measuring cup. Each bottle along with the package insert is placed in individual cardboard boxes.
Buy Ibufen Forte Susp. d/pr.orally 200mg/5ml in vial. 100ml per pack. No. 1 in pharmacy
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