Side effects
In adults:
- diarrhea, nausea, bloating;
- allergic reactions;
- dehydration (rare).
In children:
- acute, prolonged abdominal pain;
- excessive gas formation , nausea;
- Itching of the skin and urticaria .
Contraindications
The medicine should not be taken if:
- hypersensitivity to macrogol or other substances included in the composition;
- inflammatory diseases of the gastrointestinal tract in the acute phase;
- painful sensations in the abdomen of unknown origin;
- intestinal obstruction;
- congenital enlargement of the large intestine combined with narrowing;
- ulcers and Crohn's disease;
- holes in the walls of the intestines/stomach or at risk of their formation;
- the likelihood of surgical intestinal pathology;
- suspected gynecological surgical pathology.
Instructions for use of Forlax (Method and dosage)
The course of administration and dosage should be determined depending on the characteristics of digestion.
Usually, based on the instructions for use of Forlax, children and adults are prescribed one or two sachets per day. It is best to take one packet in the morning and one in the evening. The effect of taking it occurs within one or two days. The children's dosage is most often one sachet.
How long to take the drug?
The course of treatment is usually three months, unless the doctor prescribes otherwise. If at the end of the course there are no positive changes, you should choose another medicine.
At the end of the intake, it is recommended to switch to eating foods rich in fiber, move more, and lead an active lifestyle.
Forlax 10g (10.167g) 20 pcs. powder for solution for oral administration
pharmachologic effect
Osmotic laxative drug.
The large molecular weight of macrogol 4000 is due to long linear polymers that hold water molecules through hydrogen bonds. Due to this, after oral administration of the drug, the volume of intestinal contents increases. The volume of unabsorbed fluid that is located in the intestinal lumen maintains the laxative effect of the solution. The laxative effect of Forlax occurs 24-48 hours after administration.
Composition and release form Forlax 10g (10.167g) 20 pcs. powder for solution for oral administration
Powder - 1 pack:
- Active substance: macrogol 4000 10 g.
- Excipients: orange-grapefruit flavor (orange oil, grapefruit oil, concentrated orange juice, citral, acetaldehyde, linalol, ethyl butyrate, α-terpineol, octanal, cis-3-hexenol, maltodextrin, acacia gum, sorbitol (E420), sulfur dioxide (E220), butylated hydroxyanisole (E320)) - 0.15 g, sodium saccharinate - 0.017 g.
10.167 mg - laminated paper bags (20) - cardboard packs.
Description of the dosage form
Powder for the preparation of a solution for oral administration; white or almost white in color, with the smell of orange and grapefruit; Easily soluble in water to form a white translucent solution.
Characteristic
The drug belongs to the group of osmotic laxatives.
Directions for use and doses
Take orally, preferably 1-2 packets 1 time / day in the morning or 1 packet 2 times / day - morning and evening.
The daily dose is adjusted according to the clinical effect.
The contents of each package should be dissolved in a glass of water immediately before use.
The recommended course of treatment for adults and children aged 8 years and older is 3 months. In children, treatment should not exceed 3 months due to insufficient clinical data.
After restoring normal bowel function, the patient must maintain the effect: lead an active lifestyle and include foods rich in plant fiber in the diet.
If symptoms of constipation persist for more than 3 months, a further extensive diagnostic evaluation should be performed.
Pharmacodynamics
The high molecular weight compound Macrogol 4000 is a long linear polymer that holds water molecules through hydrogen bonds. Due to this, after oral administration of Macrogol 4000, the volume of intestinal contents increases. Unabsorbed liquid, which is located in the intestinal lumen, maintains the laxative effect of the solution.
Pharmacokinetics
Pharmacokinetic data confirm that when taken orally, macrogol 4000 undergoes neither gastrointestinal absorption nor biotransformation.
Indications for use Forlax 10g (10.167g) 20 pcs. powder for solution for oral administration
Symptomatic treatment of constipation in adults and children aged 8 years and older.
Contraindications
- Serious inflammatory bowel diseases (ulcerative colitis, Crohn's disease);
- toxic megacolon in combination with symptomatic stenosis;
- perforation or threat of perforation of the gastrointestinal tract;
- intestinal obstruction or suspected intestinal obstruction;
- abdominal pain of unknown etiology;
- children under 8 years of age;
- hypersensitivity to macrogol (polyethylene glycol) or other components of the drug.
Application of Forlax 10g (10.167g) 20 pcs. powder for the preparation of a solution for oral administration during pregnancy and lactation
The systemic effect of the drug Forlax® is insignificant, so no negative effects on the body of the mother and fetus are expected. Forlax® can be taken during pregnancy.
The systemic effect of macrogol 4000 on the body of lactating women is insignificant, so no negative effect on the body of a newborn/infant is expected. Forlax® can be used during lactation (breastfeeding).
Experimental studies on animals have shown that macrogol 4000 does not have a teratogenic effect.
Use in children
Contraindicated for use in children under 8 years of age.
special instructions
Before starting therapy, organic gastrointestinal diseases should be excluded.
Treatment of constipation with medications is recommended only as an addition to a healthy lifestyle and diet, for example: increasing fluid and fiber intake; adequate physical activity, which helps restore gastrointestinal motility.
If diarrhea develops, extreme caution should be taken in patients predisposed to fluid and electrolyte imbalances (for example, elderly patients, patients with impaired liver or kidney function, or patients taking diuretics); in such cases, it is necessary to monitor the electrolyte content.
There have been reports of cases of aspiration when large volumes of polyethylene glycol with electrolytes are administered through a nasogastric tube. Children with neurological disorders involving swallowing problems are at risk for aspiration.
Very rare cases of hypersensitivity (including rash, hives, swelling) have been reported when taking drugs containing macrogol (polyethylene glycol). In exceptional cases, anaphylactic shock has been observed.
Forlax® contains sorbitol, so the drug should not be used in patients with congenital fructose intolerance.
Forlax® contains sulfur dioxide, so in rare cases, serious allergic reactions and bronchospasm may occur.
Forlax® does not contain large amounts of carbohydrates or polyols (sugar alcohols), so the drug can be prescribed to patients with diabetes mellitus, as well as to patients whose diet excludes galactose.
Impact on the ability to drive vehicles and operate machinery
The drug does not affect the ability to drive vehicles or operate machinery.
Overdose
Symptoms: ;diarrhea, which stops when the dose of the drug is reduced or treatment is stopped.
Treatment: Excessive fluid loss due to diarrhea or vomiting may require correction of electrolyte abnormalities.
Side effects Forlax 10g (10.167g) 20 pcs. powder for solution for oral administration
Adults
Side effects that were observed during clinical trials involving 600 patients were transient in nature.
From the digestive system: ;often (>1/100, 1/1000,
Additional information obtained from post-marketing surveillance
Allergic reactions: ;very rare (
From the digestive system: frequency unknown - diarrhea leading to electrolyte imbalance (hyponatremia, hypokalemia) and/or dehydration, especially in adults.
Children
Side effects observed in clinical studies involving 147 children aged 6 months to 15 years were minimal and transient.
From the digestive system: ;often (>1/100, 1/1000,
Allergic reactions: Frequency cannot be estimated based on available data - hypersensitivity reactions.
Drug interactions
The interaction of Forlax® with other drugs has not been described.
Forlax® slows down the absorption of concomitantly taken medications. Therefore, it is recommended to prescribe it no earlier than 2 hours after taking other drugs.
Analogs
Level 4 ATC code matches:
Romphalac
Transipeg
Normolakt
Medulak
Fortrans
Exportal
Fleet Phospho-Soda
Good luck
Lactulose
Sorbitol
Duphalac
Normaze
Analogs of the drug are: biofrolax, duphalac, Lactulose - mip, medulak, Normolakt, flit phospho-soda, endofalk, fortrans, transulose, movipret, magnesium sulfate, lactuvit, depurax .
Reviews of Forlax
Reviews of Forlax on the forums : A good, effective drug. Many people like the sweet taste and mild action of the product. Sometimes individual intolerance and side effects in the form of vomiting are observed. Some people are confused by the price. It should be remembered that the medicine does not eliminate the cause of constipation.
Reviews of Forlax for children : Prescribed to children from six months. As a rule, it is well tolerated without causing bloating. Children like the taste and it has a convenient dosage form.
special instructions
Pathologies of the gastrointestinal tract must be excluded before using Forlax. It is used as an additional remedy, the main thing in the treatment of constipation is proper nutrition, adherence to the drinking regime and physical activity.
Patients with a tendency to water-electrolyte imbalance should avoid the development of diarrhea during treatment with the drug. For persons with impaired liver or kidney function, or those taking diuretics, it is important to monitor electrolyte balance in a laboratory.
Forlax price, where to buy
The price of Forlax in a dosage of 10 g is approximately 133 rubles for 10 sachets.
Forlax 4 g costs about 244 rubles for 20 pieces.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Forlax powder for intravenous injection solution.
approx. 10g 20 pcs Beaufour Ipsen RUB 263 order - Forlax powder for intravenous injection solution. approx. for children 4g 20 pcs Beaufour Ipsen
RUB 245 order
Pharmacy Dialogue
- Forlax sachets 10g No. 20Beaufour Ipsen Industrie
RUB 295 order
- Forlax (pack 10g No. 20)Beaufour Ipsen Industrie
RUB 287 order
- Forlax sachets 4g No. 20Beaufour Ipsen Industrie
RUB 247 order
- Forlax (por.d.prig.r-ra d.pr.inside (for children) 4g No. 20) Bofur Ipsen Industry
RUB 266 order
- Forlax (pack 4g No. 20Yamanouchi
RUB 244 order
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Pharmacy24
- Forlax pack.
10g N20 Beaufour-Ipsen Industrie, France 151 UAH order
PaniPharmacy
- Forlax Forlax por. 10g No. 20 France, Beaufour Ipsen Industrie
173 UAH order
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