Hiporhamin
Hyporamine is prescribed as early as possible in the course of the disease. The highest therapeutic effect is achieved by combining dosage forms of hyporamin with general resorptive and local action.
For influenza, adenovirus, respiratory syncytial or other viral infections of the upper respiratory tract, the following are prescribed: sublingual tablets of 0.02 g; suppositories of 0.05 g (adults) and suppositories of 0.03 g (children); lyophilized hyporamin 0.02 g, which is used in the form of an aqueous solution prepared ex tempore by adding sterile distilled water to a bottle in a volume of 10 ml (to obtain a 0.2% solution) or 20 ml (to obtain a 0.1% solution).
Sublingual tablets are used to sanitation the oral cavity, for which they are kept in the mouth until they are completely absorbed. In this case, adults are prescribed 1 tablet 4-6 times a day, children over 12 years old - 1 tablet 3-4 times a day, children from 3 to 12 years old - 1 tablet 2-4 times a day, depending on age. Sublingual tablets are not used for children under three years of age.
Suppositories of 0.05 g for adults and 0.03 g for children are prescribed per rectum as a dosage form with general resorptive action 1-2 times a day, depending on the severity of the process (presence of pneumonia, hyperthermia, etc.). Children under 3 years of age are treated with suppositories once a day without sublingual tablets.
Inhalation hyporamin is administered using various inhalation devices (U-1, Ultrasound-70, AI-1, etc.): adults - 0.2% aqueous solution up to 10 ml per inhalation; children - 0.1% aqueous solution: older children - up to 10 ml per inhalation, young children - up to 5 ml per inhalation.
In the presence of rhinitis, a 0.2% solution of 4-6 drops is instilled into each nasal passage for adults, 4-6 drops 3-4 times a day, for children - a 0.1% solution of 2 to 4 drops (depending on age) 2-3 times a day.
Duration of treatment: for influenza, at least 3 days. For parainfluenza, RS-viral, adenoviral, mixed infections and other acute respiratory viral infections - at least 5 days.
For individual prevention during an influenza outbreak, sublingual hyporamin tablets, per rectum suppositories and nasal drops are used according to the same schemes.
For chickenpox, herpes zoster, herpesvirus and cytomegalovirus infections, as well as other viral lesions of the skin and mucous membranes, the following are used: sublingual tablets of 0.02 g; ointment 0.5%; rectal and vaginal suppositories, 0.05 g each (for adults); suppositories 0.03 g (for children). Sublingual tablets are prescribed for adults and children over 12 years old, 1 tablet 4-6 times a day, for children 6-12 years old - 1 tablet 3-4 times a day, for children 3-6 years old - according to Vi
tablets 2-4 times a day; tablets are not prescribed for children under 3 years of age. Ointment 0.5% is applied to the lesions 4-6 times a day. As a general resorptive antiviral agent, suppositories with hyporamin per rectum are prescribed simultaneously for all forms of the disease up to 3 times a day: adults - 0.05 g and children over 3 years old - 0.03 g. Children under 3 years old, suppositories 0.03 g is used once a day. For genital herpes, suppositories are additionally administered intravaginally 1-2 times a day: adults - 0.05 g, children - 0.03 g. The duration of use depends on the severity of the process and is 3-10 days for mild forms of the disease. For severe and recurrent forms of the disease, the minimum course of treatment is 2-3 weeks. Repeated courses of treatment are advisable.
In conditions of immunosuppressive therapy, in postoperative patients, in risk groups, etc., it is advisable to use hyporamin to prevent the development of viral complications. In this case, for the prevention of herpesvirus diseases and CMV infection, hyporamin is used in the form of sublingual tablets of 0.02 g 3 times a day and/or suppositories per rectum 2 times a day, for 5-7 days.
Buy Hyporamine sublingual tablets. 20mg No. 20 in pharmacies
Giporamine Buy Giporamine in pharmacies DOSAGE FORMS sublingual tablets 0.02g sublingual tablets 0.02g
MANUFACTURERS Vilar (Russia) Pharmcenter Vilar CJSC (Russia)
GROUP Antiviral agents of different groups
COMPOSITION Active substance - polyphenolic complex of galloellagitannins. 1 sublingual tablet contains 0.02 g of active substance
INTERNATIONAL NON-PROPENTED NAME no
PHARMACOLOGICAL ACTION Hyporamine is a dry purified extract from the leaves of sea buckthorn, which is a polyphenolic complex of galloellagitannins, the biologically active components of which are hydrolyzable tannins, which have common structural elements in the form of glucose-galloyl and hexahydroxy-phenoyl residues. Hyporamine has pronounced antiviral activity against various strains of influenza A and B viruses, adenoviruses, paramyxoviruses, herpes simplex viruses, herpes zoster, cytomegaloviruses, respiratory syncytial virus, human immunodeficiency viruses (HIV infection). The mechanism of action of Giporamin is based on the inhibitory effect on viral neuraminidase. The inhibitory effect of Hyporamine on viral reproduction manifests itself in the early stages of their development. Hyporamine induces the production of interferon in blood cells in in vitro experiments and increases the content of interferon in the blood of patients. In in vitro experiments, the drug also has a moderate antimicrobial effect against gram-positive and gram-negative bacteria, tuberculous mycobacteria, candida, and some filamentous fungi. Hyporamine is low toxic. It does not have allergenic, mutagenic, teratogenic or carcinogenic properties, and does not affect the immune status of the body.
INDICATIONS FOR USE Hyporamine sublingual tablets are used in adults and children (aged 3 years and older) as a therapeutic and prophylactic agent for influenza (A and B), parainfluenza, respiratory syncytial, adenovirus and other acute respiratory viral infections; tonsillitis occurring against the background of acute respiratory viral diseases and accompanied by rhinitis; for acute and recurrent forms of herpes simplex of extragenital and genital localization, for herpes zoster, chicken pox and cytomegalovirus infection and other infections caused by viruses sensitive to the drug.
CONTRAINDICATIONS Individual intolerance.
SIDE EFFECTS: With long-term use in doses exceeding those specified in the instructions, increased blood clotting is possible.
INTERACTION No data available.
METHOD OF APPLICATION AND DOSAGE Hyporamin is prescribed as early as possible in the course of the disease. For influenza, adenovirus, respiratory syncytial or other viral infections of the upper respiratory tract, sublingual tablets are prescribed. Sublingual tablets are used to sanitize the oral cavity, in order to get rid of the virus, for which they are kept in the mouth until they are completely absorbed. In this case, adults are prescribed 1 tablet 4-6 times a day, children over 12 years old - 1 tablet 3-4 times a day, children from 3 to 12 years old - 1/2-1 tablet 2-4 times a day, depending on age. Sublingual tablets are not prescribed to children under 3 years of age. Duration of treatment: for influenza, at least 3 days. For parainfluenza, RS-viral, adenoviral, mixed infections and other acute respiratory viral infections - at least 5 days. For individual prevention during an influenza outbreak, sublingual Giporamin tablets are used according to the same schemes. For chickenpox, herpes zoster, herpesvirus and cytomegalovirus infections, as well as other viral lesions of the skin and mucous membranes, Giporamin is prescribed in sublingual tablets for adults and children over 12 years old, 1 tablet 4-6 times a day, for children 6-12 years old - 1 tablet 1 tablet 3-4 times a day, children 3-6 years old - 1/2 tablet 2-4 times a day, tablets are not prescribed for children under 3 years old. The duration of use depends on the severity of the process and for mild forms of the disease is 3-10 days. For severe and recurrent forms of the disease, the minimum course of treatment is 2-3 weeks. Repeated courses of treatment are advisable. In conditions of immunosuppressive therapy, in postoperative patients, in risk groups, etc., it is advisable to use Hyporamine to prevent the development of viral complications. At the same time, for the prevention of herpes viral diseases and CMV infection, Giporamin is used in the form of sublingual tablets of 0.02 g 3 times a day for 5-7 days.
OVERDOSE When using the drug in the form of sublingual tablets, no intoxication was observed.
SPECIAL INSTRUCTIONS No data available.
STORAGE CONDITIONS Store in a dry place, protected from light and out of reach of children.
