Vizin eye drops: instructions for use, price, reviews and analogues

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The active substance is a sympathomimetic, stimulating alpha-adrenergic receptors , with virtually no effect on beta-adrenergic receptors . Tetrizoline has a vasoconstrictor effect, reduces redness and swelling. After instillation, the effect appears within 60 seconds and lasts from 4 to 8 hours.

Pharmacokinetics

When used topically, it is almost not absorbed and has no systemic effect. More detailed pharmacokinetic studies have not been conducted.

Pharmacological properties of the drug Vizin

Pharmacodynamics. Tetrizoline is a sympathomimetic agent that directly stimulates α-adrenergic receptors of the sympathetic nervous system, while having little or no effect on β-adrenergic receptors. As a sympathomimetic amine, tetrizoline has a vasoconstrictor effect and thus reduces tissue edema and excessive exudation. The use of the drug leads to a decrease in burning, irritation, itching, pain and lacrimation. Pharmacokinetics. The action develops within a few minutes after instillation into the affected eye and lasts up to 4 hours. Tetrizoline is practically not absorbed when applied topically, if used in recommended doses.

Vizin eye drops, instructions for use (Method and dosage)

Eye drops are instilled 1-2 times per eye 2-3 times a day. Use for more than 4 days in a row is not recommended. To instill, you need to remove the cap from the bottle and turn it over. Without touching the surface of the mucous membrane of the eyes, drop the required amount and screw on the cap.

Is it possible for children to drip? The drug is approved for use in children over 2 years of age. It is prescribed for children under the supervision of a doctor.

Is it possible to drip with lenses? Contact lenses should be removed before instilling the drug and installed after approximately 15 minutes.

The instructions for use of Visin contain a warning that the drug should be used only for minor eye irritation. If the condition does not improve within two days, you need to discontinue the drug and carry out further treatment as recommended by your doctor. Drops are not intended for the treatment of bacterial conjunctivitis , foreign bodies in the eye or corneal injuries.

Visine for acne

Indications for use do not include its use against acne. However, if we consider the composition of the drug and the description of the action, we can conclude that a rapid, persistent vasoconstrictor effect and the elimination of redness can be used in this case. To do this, apply a cotton swab soaked in the drug to the problem area for 5 minutes. If the inflammation is severe and the size is impressive, you can repeat the procedure 2-3 times (effective on the skin for up to 4 hours). This is evidenced by reviews from visitors to some sites:

“...It helps a lot, I use it in emergencies”;
“... Even a cosmetologist advised me. You need to apply a cotton pad soaked in Visine. First keep the disc in the freezer”;
“... Stops bleeding if you squeeze out a pimple and makes redness less noticeable”;
“... It really does reduce pimples in a matter of minutes, but if you’ve eaten a lot of pimples, this won’t save you.”

You can use the drug for this purpose situationally, if you need to quickly “get your face in order,” but you cannot use it constantly, since it does not have a therapeutic effect on acne (antiseptics and agents that improve the function of the sebaceous glands are needed here) and, in addition, causes a number of side effects with long-term use. It helps to mask acne, rather than get rid of it. You can get rid of acne only with the help of professional cosmetics.

Visine classic eye drops 0.05% 15ml

A country

Belgium
Country of manufacture may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.

Active substance

Tetrizoline

Compound

The active ingredient is tetrizoline hydrochloride.

pharmachologic effect

Tetrizoline is an adrenomimetic drug that stimulates alpha-adrenergic receptors of the sympathetic nervous system, but has no or weak effect on beta-adrenergic receptors. Being an adrenomimetic amine, tetrizoline has a vasoconstrictor effect and reduces tissue swelling. The effect begins 60 seconds after instillation and lasts 4-8 hours. When applied topically, systemic absorption is possible in patients with damage to the mucous membrane and epithelium. Detailed pharmacokinetic studies have not been conducted following topical application of eye drops.

Indications for use

To relieve swelling and hyperemia of the conjunctiva (redness of the eyes), caused by exposure to chemical and physical factors (smoke, wind, dust, chlorinated water, light, cosmetics, contact lenses), as well as those arising from allergic reactions such as hay fever.

Mode of application

Locally. Adults and children over 2 years old, 1 drop into the affected eye 2-3 times a day. Use of the drug for more than 4 days should only be done under the supervision of a physician.

Interaction

The drug "Vizin Classic" should not be used simultaneously with MAO inhibitors such as tranylcypromine, tricyclic antidepressants, or drugs that increase blood pressure. Combination therapy with these groups of drugs can lead to increased vasoconstrictor effects and increased blood pressure.

Side effect

Uncommon: reactive hyperemia, burning sensation, dry mucous membranes, systemic disorders (for example, palpitations, headache, tremor, weakness, sweating and increased blood pressure). Blurred vision, conjunctival irritation, or rarely mydriasis may occur. In addition, systemic adrenomimetic effects are infrequently observed. In isolated cases, after long-term use of tetrizoline, keratinization of the epithelium (xerosis) of the conjunctiva with occlusion of the lacrimal openings and epiphora has been reported.

Contraindications

Hypersensitivity to the components of the drug, angle-closure glaucoma, children under 2 years of age.

Overdose

Symptoms: Excessive systemic absorption of alpha-adrenomimetic imidazole derivatives can lead to depression of the central nervous system, which is manifested by drowsiness, low body temperature, bradycardia, shock-like hypotension, apnea and coma. Symptoms of overdose are mydriasis, nausea, cyanosis, fever, convulsions, tachycardia, arrhythmia, cardiac arrest, increased blood pressure, pulmonary edema, respiratory dysfunction, and mental disorders. The risk of overdose symptoms associated with the absorption of the drug is especially high in newborns and small children if swallowed, resulting in possible disturbances in the central nervous system, as well as respiratory depression and collapse. The toxic dose of tetrizoline is 0.01 mg per kilogram of body weight. Treatment : In case of overdose, activated charcoal, gastric lavage, oxygen inhalation, antipyretics and anticonvulsants are prescribed. To lower blood pressure, use phentolamine 5 mg in saline solution slowly intravenously or 100 mg orally. Vasopressor drugs are contraindicated in patients with low blood pressure. In case of symptoms caused by blockade of m-cholinergic receptors, the antidote physostigmine is used. If any symptoms of overdose appear, consult a doctor immediately!

special instructions

Contact lenses should be removed before instilling the drug and installed after 15 minutes. It is necessary to avoid direct contact of the drug with soft contact lenses due to possible disruption of their transparency. The development of reactive hyperemia of the conjunctiva and nasal mucosa (rhinitis medicamentosa) may develop due to improper use of the drug. If you experience intense pain in the eyes, severe acute or unilateral redness of the eyes, headaches, blurred vision, spots before the eyes or double vision, you should immediately consult a doctor. If irritation or redness is associated with serious diseases of the organ of vision: infection, foreign body or chemical injury to the cornea, consultation with an ophthalmologist is necessary. Long-term use and overdose of the drug should be avoided, especially in children. If the medicine has become unusable or has expired, do not pour it into wastewater or throw it outside! Place the medication in a bag and place it in the trash. These measures will help protect the environment! In rare cases, after using Visin Classic eye drops, blurred vision occurs, which can affect the ability to drive a car and operate machinery.

Overdose

If you use the product in accordance with the instructions, the risk of overdose is minimal. In case of accidental contact with the stomach, nausea, dilated pupils, cyanosis , fever , increased blood pressure , convulsions , tachycardia , pulmonary edema , arrhythmia , impaired respiratory and central nervous system .

The risk of overdose is high in young children if the drug is swallowed. Treatment begins with gastric lavage and taking activated charcoal . Next, symptomatic therapy is carried out: oxygen inhalation, antipyretics and anticonvulsants. If blood pressure phentolamine is slowly administered intravenously , 5 mg in saline solution. Antidote unknown.

Special instructions for the drug Vizin

Children aged 2 to 6 years should use the drug with caution. For patients with severe diseases of the cardiovascular system (coronary artery disease, hypertension (arterial hypertension)), pheochromocytoma, metabolic disorders (hyperthyroidism, diabetes mellitus), as well as patients receiving MAO inhibitors or other drugs that can increase blood pressure, Visine should only be prescribed if the potential benefit outweighs the potential risk. Too frequent use of the drug can lead to the development of conjunctival hyperemia. It is advisable to use Visine only for minor eye irritation. The patient should be warned that if the condition does not improve within 48 hours, irritation or hyperemia persists or worsens, the drug should be discontinued. If irritation or hyperemia is associated with serious diseases of the organ of vision (infection, foreign body, chemical injury to the cornea), the patient should consult a doctor; If intense eye pain, headache, rapid loss of vision, sudden appearance of floating spots in front of the eyes, redness of the eyes, photophobia or diplopia occur, the patient should consult a doctor immediately. Long-term use of the drug and overdose should be avoided, especially in children. Before instilling the drug, contact lenses should be removed. Direct contact of the drug with soft contact lenses should be avoided, given the risk of compromising their transparency. If the solution changes color or becomes cloudy, the drug is not suitable for use. During pregnancy and breastfeeding. Considering the insignificant risk of developing systemic effects, the drug can be used during pregnancy and breastfeeding only if the potential benefit outweighs the possible risk. Impact on the ability to drive vehicles and work with potentially dangerous mechanisms. Sometimes after using the drug, mydriasis and blurred vision are observed, which can reduce the ability to drive vehicles and work with potentially dangerous mechanisms.

Visin's analogs

Level 4 ATX code matches:
VizOptic

Visine Classic

Oxymetazoline

Okumetil

Among the drugs containing the active substance tetrizoline , we can name eye drops Montevisin , Spersallerg , Visoptic , Octilia , Naphazolin . The price of Visin analogues is: Visoptik 15 ml - 121-182 rubles, Montevisin 10 ml for 116-153 rubles, Octilia 8 ml for 203-364 rubles. Consequently, the cheapest analogue, taking into account the amount of substance in the bottle, is Visoptik , Rompharm Company (Romania).

Reviews of Visine

Decongestants are vasoconstrictors used topically. Tetrizoline is the active ingredient in Tizin nasal drops; Visin eye drops also contain it. The use of tetrizoline is accompanied by constriction of blood vessels (and not only local ones), a decrease in blood supply and elimination of edema - in our case, this is the conjunctiva of the eyes. Advertising for the drug contains this information and recommends using drops only for mild redness caused by allergies or irritating effects of dust, chlorinated water, etc.

Vasoconstrictor eye drops are used short-term, even situationally (for example, after exposure to chlorinated water in a swimming pool), since long-term use can cause side effects: dilated pupils, burning, even greater redness and drug-induced conjunctivitis .

Now that we have found out what Visine is, the question arises as to how advisable it is to use it for acne. Such cases occur, and consumers share their impressions of using this product. The effect is really noticeable and is due to the narrowing of blood vessels and a decrease in redness. The drug in this case is used for “emergency camouflage” of unwanted pimples, but it is not a treatment for acne .

Those patients who have used the drug as directed leave positive reviews about Visin drops - it acts quickly and eliminates redness in allergic conjunctivitis . However, it was used only for the first 3-4 days with severe swelling and inflammation and in combination with H1 blockers Allergodil and Opatanol drops . Patients with allergic conjunctivitis during the flowering period of plants refused to wear lenses, which increased irritation and inflammation.

“... Good drops, my irritation from chlorinated water immediately relieves, but I rarely use it - only in emergency cases.”
“...It does a great job with eye redness.”
“... I really like it, really for all occasions - if I don’t sleep enough and my eyes turn red, then I use it, I eliminate swelling of the eyelids by applying a drop of the drug, and it even helps with pimples.”

It must be remembered that classic Visine is not intended for constant instillation for fatigue and pain in the eyes after working at the computer. There are artificial tear preparations for this purpose. There are many reviews that the drug has side effects, and some have used the drug incorrectly.

“... It helps great, but it dries out the eyes and you get used to it.”
“... The doctor prescribed it and said you can’t use it regularly! Increases intraocular pressure."
“... I work at the computer and suffer from constant eye fatigue. I used Visine for a month and my vision dropped by 2 units.”
"… I like! But once I used it every day until they ran out, my eyes were in terrible condition.”

Reviews about Vizin classic

The vasoconstrictor effect of tetrizoline , the active ingredient of Vizin classic, manifests itself very quickly and is accompanied by a decrease in blood supply and redness of the conjunctiva of the eyes. This is evidenced by reviews of people who, for various reasons, resorted to their use:

“...I get irritated from chlorinated water, so I use these drops periodically. They give effect very quickly."
“... My eyes turn red if I work a lot and don’t get enough sleep. In the morning I drop it in and after 20 minutes the whites are white, it does a great job.”
“... I really like it, it’s suitable for all cases when the eyes are red - after the pool, with lack of sleep, stress on the computer.”
“... It’s very convenient to use Visine in ampoules—you can take it to work or to the pool. I always have it in my bag for emergencies.”
“... I take Visin ampoules with me on business trips, they always help out after a sleepless night on the train.”

Vasoconstrictor eye drops should be used for a short time, as adverse reactions may occur: dry eyes, dilated pupils. It is absolutely not permissible to use them if your eyes are tired while working at the computer. Many patients did not take this into account and used the drug incorrectly, resulting in unwanted effects.

“... After using it for two weeks, I noticed that dryness and pain appeared in the eyes.”
“... I used it every day for almost a month, my eyes turned even redder and were in a terrible state.”
“... I spend the whole day at the computer, my eyes get tired and red. I didn’t take into account that you can’t use Visine for a long time and used it for a whole month - my eyes got even worse. Don't repeat my mistake."

To eliminate dryness of the conjunctiva and pain in the eyes, which often occurs when working at a computer, you need to use artificial tear preparations.

Visine price, where to buy

You can buy the drug at any pharmacy. How much do these drops cost in the pharmacy today? The cost depends on their varieties and volume in the bottle. If we consider the classic Visin eye drops, their price is 238-289 rubles. for 15 ml. Vizin Allergy eye drops 4 ml is 228-249 rubles, and Vizin Pure Tear 10 ml is even more expensive - 469-605 rubles.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

ZdravCity

Visin Classic eye drops, pl.
Bottle, 15 mlJanssen Pharmaceuticals N.V. RUB 404 order
Vizin Classic eye drops amp 0.05% 0.5ml 10 pcs. Laboratuar Uniter
RUR 444 order
Vizin Alergy eye drops 0.05% 4ml Famar S.A.
415 rub. order

Pharmacy Dialogue

Visine classic eye drops 0.05% ampoules 0.5ml No. 10Laboratoire Unither
RUB 445 order
Visine classic eye drops 0.05% 15mlKeata Pharma
412 rub. order
Visin Alergy eye drops 0.05% 4mlFamar L'Aigle
402 rub. order

Pharmacy24

Vizin Classic 15 ml drops Janssen Pharmaceuticals N.V., Belgium
83 UAH order

PaniPharmacy

Visine liquid Visine classic eye drops 0.05% 15ml Belgium, Janssen
117 UAH. order

Price Vizin classic, where to buy

You can buy the drug at any pharmacy. The price of Visine classic in ampoules of 0.5 ml No. 10 ranges from 262 to 433 rubles.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine

ZdravCity

Visin Classic eye drops, pl.
Bottle, 15 mlJanssen Pharmaceuticals N.V. RUB 404 order
Vizin Classic eye drops amp 0.05% 0.5ml 10 pcs. Laboratuar Uniter
RUR 444 order

Pharmacy Dialogue

Visine classic eye drops 0.05% ampoules 0.5ml No. 10Laboratoire Unither
RUB 445 order
Visine classic eye drops 0.05% 15mlKeata Pharma
412 rub. order

Pharmacy24

Vizin Classic 15 ml drops Janssen Pharmaceuticals N.V., Belgium
83 UAH order