Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Alpha adrenomimetic , which has a vasoconstrictor and anti-edematous effect. Reduces swelling of the conjunctiva, soreness of the eye mucosa, burning, lacrimation. The vasoconstrictor effect begins a few minutes after application and lasts 4-8 hours. It can be used in the form of nasal drops, which act as a decongestant (reduce blood supply to the mucous membrane, reduce swelling , eliminate nasal congestion).
Pharmacokinetics
Systemic absorption when instilled into the eyes is low.
Contraindications
- glaucoma;
- corneal dystrophy;
- bacterial conjunctivitis;
- age up to 3 years;
- foreign body of the eye;
- acute cardiovascular failure;
- increased sensitivity.
It is prescribed with caution for high blood pressure , arrhythmia , hyperthyroidism , diabetes mellitus , pheochromocytoma , severe forms of coronary artery disease , and during treatment with MAO inhibitors , which increase blood pressure.
Features of application
Pregnant
The drug should be used only if the expected benefit to the mother outweighs the potential risk to the child.
Children
The drug is not used in children under 2 years of age.
Children aged 2 to 6 years should use the drug with caution, under medical supervision.
Drivers
The effect is unlikely, but immediately after using the drug you should wait until your vision is cleared before operating vehicles or other machinery.
Side effects
Local reactions:
- increased intraocular pressure ;
- pupil dilation;
- burning and hyperemia of the eyes;
- burning in the nose, sneezing, secondary swelling of the nasal mucosa, dryness of the nasal mucosa (when applied to the nose).
Systemic reactions:
- increased blood pressure ;
- heartbeat;
- headache;
- weakness;
- dizziness;
- tremor;
- nausea;
- insomnia;
- hyperglycemia.
Visoptik, instructions for use (Method and dosage)
Visoptic eye drops are prescribed to adults and children over 3 years of age. Apply 1-2 drops 2 or 3 times a day in each eye. Continuous use of drops for more than 4 days is not allowed. If there is no improvement after 2 days of using the drops, you should consult a doctor.
If pain in the eyes intensifies, vision disturbances in the form of double vision and “floating spots”, or headaches occur, you should urgently consult a doctor. Contact lenses are installed 15-20 minutes after instillation and removed before the next instillation, avoiding direct contact of the drops with the contact lenses. After using the drug, short-term blurred vision and dilation of the pupil are possible; this must be taken into account when driving and caution must be exercised.
Visoptic eye drops 0.05% 15ml fl cap 1 pc. in Saratov
Latin name
VisOptic
International nonproprietary name
tetrizoline
Release form
Eye drops.
Package
15 ml - plastic bottles with a drip device (1) - cardboard packs.
Description
Eye drops are transparent, colorless.
pharmachologic effect
Alpha adrenergic agonist. Has a vasoconstrictor and anti-edematous effect. When applied topically, it reduces swelling of the conjunctiva, burning sensations, soreness of the mucous membrane of the eyes, and lacrimation. The vasoconstrictor effect develops within a few minutes and lasts 4-8 hours. Pharmacokinetics When applied topically, systemic absorption is low.
Indications
Moderate eye irritation: itching, swelling and hyperemia of the conjunctiva, burning, lacrimation, injection of the sclera, caused by chemical and physical factors (dust, cosmetics, swimming in chlorinated water, exposure to bright light or radiation from a computer monitor); allergic conjunctivitis.
Directions for use and doses
For adults and children over 3 years old, instill 1-2 drops 2-3 times a day into the lower conjunctival sac of the affected eye. If no improvement occurs within 48 hours, stop further use of the drug and consult a doctor.
Compound
1 ml tetrizoline hydrochloride 500 mcg Excipients: boric acid, sodium tetraborate decahydrate, disodium edetate dihydrate, benzalkonium chloride, purified water.
Contraindications
Glaucoma; endothelial-epithelial dystrophy of the cornea; acute cardiovascular failure; bacterial eye infection; foreign body of the eye; children under 3 years of age; hypersensitivity to the components of the drug. The drug should be used with caution in case of arterial hypertension, arrhythmia, aneurysm, hyperthyroidism, pheochromocytoma, diabetes mellitus, severe organic diseases of the heart and blood vessels (including coronary artery disease), as well as during treatment with MAO inhibitors and other drugs that increase blood pressure.
Use during pregnancy and breastfeeding
The use of the drug during pregnancy and lactation (breastfeeding) is possible only if the expected benefit to the mother outweighs the risk to the fetus or child.
special instructions
It is advisable to use VizOptic only for mild eye irritation. If irritation and hyperemia of the conjunctiva are associated with an infectious disease, the presence of a foreign body or chemical injury to the cornea, consultation with an ophthalmologist is necessary. If within 48 hours after starting the use of eye drops, the symptoms of the disease persist, become more pronounced, or side effects appear, you should stop using the drug and consult an ophthalmologist. If you experience intense eye pain, headache, blurred vision, sudden appearance of floaters in front of your eyes, red eyes, pain when exposed to light, or double vision, you should consult a doctor immediately. When wearing contact lenses, they are removed before instillation of the drug and reinstalled 15 minutes after it. Direct contact of eye drops with soft contact lenses should be avoided due to possible disruption of their transparency. The drug should not be used simultaneously with MAO inhibitors (including phenelzine, nialamide, iproniazid) and within 10 days after stopping their use. Effect on the ability to drive vehicles and operate machinery During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration, speed of psychomotor reactions and good vision (after using eye drops, dilation of the pupil and a feeling of blurred vision are possible) .
Side effects
Local reactions: increased intraocular pressure, burning sensation and reactive hyperemia of the eye; rarely - pupil dilation. Systemic reactions: increased blood pressure, hyperglycemia, cardiac dysfunction, headache, nausea, drowsiness, weakness, tremor, dizziness, insomnia, tachycardia, allergic reactions.
Drug interactions
Concomitant use with MAO inhibitors, tricyclic antidepressants, guanethidine can cause arterial hypertension and tachycardia. Concomitant use with reserpine, insulin, propranolol, general anesthesia, and atropine increases the risk of cardiovascular effects of tetrizoline. Concomitant use with guanethidine may cause mydriasis with temporary visual impairment.
Storage conditions
The drug should be stored out of the reach of children at a temperature of 15 to 25C.
Overdose
Overdose is possible due to accidental ingestion, especially in young children. Manifested by pupil dilation, cyanosis , nausea, convulsions, the appearance of arrhythmias , increased pressure, respiratory failure, pulmonary edema central nervous system depression with collapse and coma. Treatment: gastric lavage, activated carbon , oxygen inhalation. Symptomatic treatment consists of the use of anticonvulsants, antihypertensives and antipyretics.
Interaction
Concomitant use with MAO inhibitors ( nialamide , phenelzine , iproniazid ), antidepressants (tricyclics), and guanethidine causes hypertension and tachycardia . Drops are used 10 days after stopping taking MAO inhibitors . Use with guanethidine additionally provokes mydriasis and temporary visual impairment. Combined use of resepina , insulin , atropine , general anesthetics, and propranolol increases the risk of adverse cardiovascular reactions.
Reviews about Visoptika
The use of Visoptik reduces exudation and hyperemia of conjunctival vessels. Patients who have used this drug note a quick effect on conjunctivitis and irritation of the eye mucosa, as well as its reasonable price.
- “... They act quickly, after 3-5 minutes the red mesh in the eyes disappears.”
- “... They help get rid of pain, pain and redness of the eyes, cheaper than Visine. I like very much".
- “... Long and continuous work at the computer causes discomfort and redness in the eye. I use Visoptic from time to time. No worse than Visine, which is several times more expensive.”
- “... This is an assistant for tired eyes! Helps a lot."
- “...An indispensable thing for a computer geek.”
Among the negative aspects of using drops, there is a short period of their use after opening the bottle (they are not used for a month), as well as a burning sensation when instilled. It should be remembered that these drops are prescribed for a short period of time, since long-term use may cause local adverse reactions (burning, dilated pupils, drug-induced conjunctivitis ) and systemic ones in the form of headache , increased blood pressure and insomnia . Tetrizoline is part of Cromosil and Spersallerg , which are used for allergic conjunctivitis .
Note!
Description of the drug Visoptic drops. eye, solution 0.5 mg/ml vial. 5ml No. 2 on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
Price for Vizoptik, where to buy
Visoptic eye drops can be purchased at any pharmacy. The cost of the drug in Moscow ranges from 135-190 rubles, in St. Petersburg - 126-160 rubles, you can buy the drug in Yekaterinburg for 134-140 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Visoptic eye drops 0.05% 15mlS.C.Rompharm Company SrL RUB
308 order
Pharmacy Dialogue
- VizOptic (eye drops vial-drops 0.05% 15ml) Rompharma
RUB 295 order
- VizOptic (eye drops vial-drops 0.05% 15ml) Rompharma
RUB 305 order
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Pharmacy24
- Visoptic 0.5 mg/ml 5 ml No. 2 drops Warsaw FZ, Polfa AT, Poland
53 UAH.order
Storage conditions
Store in original packaging at a temperature not exceeding 25°C.
Keep out of the reach of children.
Store the opened bottle at a temperature not exceeding 25°C.
Shelf life: 2 years.
Shelf life after opening is 28 days.
Product description certified by the manufacturer Warsaw FZ Polfa
.
Verified
Sevryukov Alexander Viktorovich