Dexpanthenol is a substance derived from the water-soluble B vitamin - pantothenic acid. It is this that the body’s need increases when the skin and tissues are damaged. To compensate for the lack of substance and accelerate cell regeneration, use the topical drug D-Panthenol.
Compound
D-Panthenol ointment for external use - dexpanthenol, lanolin , phenonip, beeswax, white paraffin, emulsifier, dietetics, propylene glycol, butylated hydroxyanisole, decamethylcyclopentasiloxane, butylated hydroxytoluene, protegin B, magnesium sulfate heptahydrate, purified water. Cream D-Panthenol 5% for external use - dexpanthenol, cetearyl octanoate, ketomacrogol, methyl parahydroxybenzoate, cetanol, propylene glycol, dimethicone, glyceryl monostearate, propyl parahydroxybenzoate, purified water, flavoring.
Panthenol in cosmetology
When answering the question of what Panthenol cream is used for, we must not forget about its use in cosmetology. It is included in products for the face, body and hair, which help in the fight against various problems - acne, dryness and irritability of the skin, wrinkles. Milk and gel for washing containing dexpanthenol, hyaluronic acid and other components soothe the skin, maintain its firmness and elasticity. Hair masks with a similar component prevent hair loss and improve hair structure. In recent years, D-Panthenol and its analogs are often used to restore skin after tattoos.
In addition, the substance is included in foot and hand creams, lipsticks and other products, but most often dexpanthenol is present in the list of components of tanning creams. It protects against the harmful effects of the sun's rays and prevents burns. Regular panthenol can be used against sunburn - it is considered the most effective and safe drug in such cases.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Dexpanthenol is a derivative of pantothenic acid, which belongs to the B vitamins (water-soluble) that are part of coenzyme A. It plays an important role in metabolic processes: the breakdown of fatty acids, the release of energy from carbohydrates, the synthesis of sterols, acetylcholine, and steroid hormones. Pantothenic acid supports the functions of the epithelium, and in cases of damage to the skin or mucous membranes, there is an increased need for it. The drug stimulates the skin regeneration process, increases the strength of collagen fibers, normalizes cellular metabolism, and has a slight anti-inflammatory effect. Hydrophilicity, optimal molecular weight and low polarity of these drugs allow the active substance to penetrate into all layers of the skin. The auxiliary substances included in the ointment and cream improve the trophism of the skin and soften it.
Pharmacokinetics
The drug is quickly absorbed from the surface of the skin, and the active substance binds to blood proteins (albumin and beta globulin).
Pharmacological features
The main active ingredient of the drug is dexpanthenol. In addition, it contains auxiliary components - lanolin, phenonip, natural wax and paraffin, emulsifiers, etc. Additional substances provide the necessary consistency of the drug and improve its therapeutic effect. For example, lanolin forms a film on the surface of the skin that prevents drying.
D-Panthenol penetrates into all layers of the skin, which provides the necessary effect, but is practically not absorbed into the bloodstream and does not affect the functioning of the liver, kidneys or other organs.
In addition to the regenerating effect, D-Panthenol has a mild analgesic and anti-inflammatory effect.
It is available in the form of a spray, cream or ointment, and is a light yellow substance with a uniform consistency and a slight pharmaceutical smell. Sold in aluminum tubes of 25 and 50 g in cardboard packages. 1 g of the drug contains 50 mg of the active ingredient.
Indications for use
- various violations of the integrity of the skin formed under the influence of mechanical, temperature and chemical factors ( burns of various origins, bedsores , abrasions, scratches, superficial wounds, long-healing skin grafts);
- aseptic postoperative wounds after surgery;
- boils , dermatitis , inflammatory processes on the skin, trophic ulcers of the extremities, inflammation and cracked nipples in nursing mothers, lower skin care near tracheostomy , colostomy , gastrostomy ;
- in children - scratches, diaper dermatitis , irritation after ultraviolet radiation, for the prevention and treatment of diaper rash ;
- prevention and treatment of the consequences of exposure to various adverse environmental factors (humidity, wind, cold) on the skin.
Contraindications and side effects
The active substance D-Panthenol is compatible with body tissues, so the drug has practically no contraindications for use. It cannot be used in case of individual intolerance or allergic reactions to individual components of the product. People with an increased tendency to allergies should use the ointment with caution, carefully monitoring the body's reaction. Pregnancy and breastfeeding are not contraindications to the use of D-Panthenol - it does not penetrate into the bloodstream or breast milk, and therefore does not harm the body of the woman and child.
Side effects from the use of D-Panthenol also develop extremely rarely. If you are hypersensitive, skin irritation, redness, itching and rash may occur.
If such reactions occur, you must stop using the drug, and if the symptoms persist for a long time, consult a doctor.
Instructions for use of D-Panthenol (Method and dosage)
D-Panthenol ointment, instructions for use: the ointment is applied externally in a thin layer to the skin in the affected area, lightly rubbing in, 2-4 (more often if necessary) times a day. If the skin area is infected, it is necessary to pre-treat it with an antiseptic. For breastfeeding women, lubricate the nipple with ointment after each feeding of the baby. Depanthenol ointment can also be used by children, including children under one year of age. For newborns, the ointment is applied after each water procedure or change of linen. The duration of use of the ointment is determined by the tolerability of the drug and the effectiveness of treatment.
Instructions for D-Panthenol cream: apply the cream externally to adults and children in a thin layer on the skin in the affected area, lightly rubbing in, 2–4 (more often if necessary) times a day, 2–4 times a day. If the skin area is infected, it is necessary to pre-treat it with an antiseptic. For nursing mothers who have cracked nipples, apply Depanthenol cream after each feeding of the baby. To treat damaged cervical mucosa and anal fissures and pathologies, it is enough to lubricate the affected areas 1-2 times a day.
It should be remembered that De-Panthenol ointment and cream are not recommended to be applied to weeping wounds. All forms of the drug are safe during pregnancy and lactation, both for the mother and the fetus.
Effects of the drug
The main effect of the drug is to help in tissue regeneration. The medication also has the following positive effects:
- relieves inflammation at the site of violation of the integrity of the skin;
- reduces irritation, including after cosmetic procedures;
- restores and moisturizes the skin, fights peeling;
- helps wounds heal faster;
- promotes faster renewal of the skin in case of burns;
- relieves chafing and redness.
Analogs
Level 4 ATC code matches:
Panthenol
Kalanchoe juice
Aloe liniment
Levomekol
Pantestin-Darnitsa
Dexpanthenol
Contractubex
Pantoderm
Bepanten
Structural analogues by ATC code and active substance: Bepanthen ; Dexpanthenol ; Panthenol Pharmstandard; Korneregel ; Panthenol-ratiopharm ; Moreal-plus ; Panthenol ; Panthenolspray ; Pantoderm .
Reviews about D-Panthenol
Reviews about D-Panthenol ointment are overwhelmingly positive. “...I used D-Panthenol for acne yesterday. Today there is nothing left even to the touch, the skin is a pleasant color. I was even a little scared, maybe it was a hormonal drug. I used them before and the effect was good, but I was advised not to use hormonal drugs. I recommend". Many patients use De-Panthenol ointment for skin burns and note the high effectiveness of this form of the drug. But, nevertheless, for burns it is better to use depanthenol cream or D-Panthenol spray (correctly - Panthenol spray), which helps well with minor thermal and sunburns.
Reviews about D-Panthenol cream are also good. “...I first became acquainted with Depanthenol when I scalded my hand. The neighbor applied cream to the burn and three days later I didn’t even remember about the burn. The second time was when my hand was cut. I cut the bread poorly. And the cream also helped a lot. The healing took a little longer this time, but the result was good. Now depanthenol cream has taken its place in my home medicine cabinet.”
Many patients are interested in which form of the drug is more effective: “for what is it better to use ointment, and for what is it better to use cream?” The choice of the form of the medicine depends on the nature of the skin of the damaged surface: the ointment contains a higher percentage of fat and the use of depanthenol ointment is recommended for dry skin in the patient. The cream does not contain fat and the use of depanthenol cream is recommended on open areas of the body and on wet wounds. In addition, d panthenol cream is easily rubbed in and quickly absorbed, so it is recommended to use it for minor burns, in particular for sunburns.
Also, many patients are interested in D-Pantol suppositories, however, some of them mistakenly search for the drug using the query “depanthenol suppositories” and do not find this dosage form. You need to look for Depantol suppositories, not Depanthenol. This dosage form is widely used in gynecology. In addition to dexpanthenol, it contains chlorhexidine bigluconate, which has pronounced antimicrobial activity, as well as dermatophytes, yeast and protozoa. Has antimicrobial, regenerating and metabolic effects.
Often on the Internet, when discussing D-Panthenol ointment and what it is best used for, you can come across recommendations for using panthenol for hair. This is true, since Panthenol has an extremely beneficial effect on hair of any type, restoring damaged structure and nourishing it. Panthenol prevents fragility, dryness, splitting and splitting, increases the scalp's resistance to negative and damaging factors, eliminates itching, and stimulates hair growth. However, in this case, it is recommended not to use Panthenol spray, but to take the drug orally in the form of capsules (Panthenol-40), which is prescribed for hair loss, splitting and brittleness, dandruff, impaired hair growth, and increased production of sebaceous glands.
Ointment, cream or spray
Panthenol is available in different forms, so many consumers are interested in the question of what are the differences between them, and in what form the drug works best. Ointment and cream practically do not differ from each other in terms of therapeutic effects, but the ointment has a denser consistency. Most often it is used for therapeutic purposes, and the cream is used for prevention.
The spray is convenient because you can take it on the road - it does not leak, and when used it does not stain your hands. When sprayed, a foam is formed, which must be applied to the damaged surface. The packaging of Panthenol with a smiley face indicates that the drug is original - there is no difference in indications and features of use.
D-Panthenol price, where to buy
How much does De-Panthenol ointment cost in Russia and Ukraine? The price of Depanthenol ointment in Russia varies between 246 -375 rubles per package. The cost of the cream in a 30 g tube is, on average, 232 rubles per package. The spray in a 200 ml bottle can be purchased for 676 rubles. The price of D-Panthenol ointment in Ukraine is 246 UAH. The price of D-Panthenol cream is 278 hryvnia per package. You can buy Depanthenol cream in most pharmacies in Moscow and the pharmacy chain in Ukraine.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
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Panthenol: properties for skin
If we talk about how panthenol works for the skin, then first of all we need to mention its regenerative effect. The product promotes rapid restoration of the epidermis. It also gradually reduces inflammation, stabilizes metabolism in cells, and strengthens collagen fibers. In addition, panthenol moisturizes the skin and is an excellent remedy for combating dryness.
For burns, injuries, wounds and various skin diseases, the product compensates for the deficiency of pantothenic acid from which it is produced. When used externally, it is well absorbed. The body converts the drug into pantothenic acid, and then binds it to plasma proteins.
!
The complex effect of panthenol on the skin has led to its demand in cosmetology and medicine.
Creams containing panthenol are used in the treatment of various skin diseases, varicose veins, cosmetic problems, etc. For example, Normaven® Foot Cream, which contains panthenol, has shown good results in the treatment of varicose veins and general improvement in the condition of the skin. This product was developed by highly qualified specialists from a pharmaceutical company, it was tested and was highly appreciated by doctors. The cream has all the necessary documentation and quality certificates and is approved for use by pregnant women. You can buy Normaven® Foot Cream in most pharmacies in the Russian Federation at an affordable price.
Panthenol - application and benefits
