Venarus 500 mg 30 pcs. film-coated tablets. obol.


Composition and properties of the drug


The tablets contain two active components: diosmin and hesperidin. Diosmin is in the highest concentration, and occupies approximately 90% of the total composition. This is a natural component that reduces the permeability of the walls of blood vessels and increases their tone, improves blood supply and reduces pressure on the vessels. In addition, it concentrates in the veins of the legs and directly affects them.

Hesperidin occupies 10% of the total composition. Its properties are similar to the previous component, but it additionally eliminates the allergic reaction, lowers blood pressure and restores good coronary duct.

Together, these two active components have a vasoconstrictor effect, provide adequate nutrition and gas exchange in all cells. This effect prevents and prevents venous insufficiency, valve failure and blood stagnation in the venous bed.

Venarus 500 mg 30 pcs. film-coated tablets. obol.

pharmachologic effect

Venotonic and venoprotective agent.

Composition and release form Venarus 500 mg 30 pcs. film-coated tablets. obol.

1 tablet contains:

  • active ingredients: hesperidin - 50 mg, diosmin - 450 mg;
  • excipients: microcrystalline cellulose 62.0 mg, sodium carboxymethyl starch (sodium starch glycolate) 27.0 mg, gelatin 31.0 mg, talc 6.0 mg, magnesium stearate 4.0 mg;
  • shell: hypromellose (hydroxypropyl methylcellulose 20.7 mg, macrogol 6000 (polyethylene glycol 6000) 3.38 mg, sodium lauryl sulfate 0.1 mg, magnesium stearate 1.24 mg, titanium dioxide 3.94 mg, iron oxide red 0.3 mg, iron oxide yellow 0.34 mg.

Film-coated tablets, 500 mg.

10 or 15 film-coated tablets in a blister pack.

2, 3, 4, 6, 7, 8, 9 strip packaging along with instructions for use are placed in a cardboard pack.

Description of the dosage form

Orange-pink film-coated tablets, biconvex, oblong in shape with rounded ends, scored. On a cross section, the kernel is grayish-yellow to brownish-gray in color.

Directions for use and doses

Inside.

The recommended dose for venous-lymphatic insufficiency is 2 tablets per day (in one or two doses): morning, afternoon and/or evening, during meals.

The duration of treatment can be several months (up to 12 months). In case of recurrence of symptoms, on the recommendation of a doctor, the course of treatment can be repeated.

The recommended dose for acute hemorrhoids is 6 tablets per day: 3 tablets in the morning and 3 tablets in the evening for 4 days, then 4 tablets per day: 2 tablets in the morning and 2 tablets in the evening for the next 3 days.

The recommended dose for chronic hemorrhoids is 2 tablets per day with food.

Pharmacodynamics

It has an angioprotective and venotonic effect. Reduces the distensibility of veins, increases their tone and reduces venous stagnation; reduces permeability and fragility of capillaries and increases their resistance; improves microcirculation and lymphatic drainage. When used systematically, it reduces the severity of clinical manifestations of chronic venous insufficiency of the lower extremities of an organic and functional nature.

Pharmacokinetics

The main excretion of the drug occurs in the feces. On average, about 14% of the administered amount of the drug is excreted in the urine.

The half-life is 11 hours.

The drug undergoes active metabolism, which is confirmed by the presence of phenolic acids in the urine.

Indications for use Venarus 500 mg 30 pcs. film-coated tablets. obol.

Treatment of symptoms of venous-lymphatic insufficiency: pain, cramps of the lower extremities, a feeling of heaviness and fullness in the legs, “fatigue” of the legs. Treatment of manifestations of venous-lymphatic insufficiency: edema of the lower extremities, trophic changes in the skin and subcutaneous tissue, venous trophic ulcers. Symptomatic treatment of acute and chronic hemorrhoids.

Contraindications

Hypersensitivity to the active components or excipients included in the drug.

The drug is not recommended for nursing women.

Effect on the body

Venotonic and angioprotective

Application of Venarus 500 mg 30 pcs. film-coated tablets. obol. during pregnancy and breastfeeding

Pregnancy

Experiments on animals did not reveal teratogenic effects. To date, there have been no reports of any side effects when using the drug by pregnant women.

Breastfeeding period

Due to the lack of data regarding the excretion of the drug into breast milk, taking the drug is not recommended for nursing women.

special instructions

In case of exacerbation of hemorrhoids, the prescription of this drug does not replace the specific treatment of other anal disorders.

The duration of treatment should not exceed the periods specified in the section “Method of administration and dosage”. If symptoms do not disappear after the recommended course of therapy, a proctological examination should be performed and the therapy used should be reconsidered.

In the presence of venous circulation disorders, the maximum effect of treatment is ensured by combining therapy with a healthy (balanced) lifestyle: it is advisable to avoid long exposure to the sun, long periods of standing, as well as reducing excess body weight. Walking and, in some cases, wearing special stockings helps improve blood circulation.

Impact on the ability to drive vehicles, operate machinery and engage in other activities that require increased concentration: no effect.

Overdose

No cases of overdose have been described.

In case of drug overdose, seek medical help immediately.

Side effects Venarus 500 mg 30 pcs. film-coated tablets. obol.

The frequency of adverse reactions is presented as follows: very often (≥1/10 cases), often (≥1/100 and

Adverse reactions, the frequency of which cannot be estimated from the available data, are designated “frequency unknown.”

From the central nervous system: rarely - dizziness, headache, general malaise; frequency unknown - convulsions.

From the gastrointestinal tract: often - diarrhea, dyspepsia, nausea, vomiting; infrequently - colitis; frequency unknown - abdominal pain.

From the respiratory system, chest and mediastinal organs: frequency unknown - sore throat, chest pain.

From the skin: rarely - rash, itching, urticaria; frequency unknown - allergic dermatitis, hyperemia, isolated swelling of the face, lips, eyelids, in exceptional cases angioedema.

If any of the adverse reactions indicated in the instructions worsen, or you notice other adverse reactions not listed in the instructions, notify your doctor.

Drug interactions

Not noted.

You should inform your doctor about all medications you are taking.

How to use

The course of administration and dose of the drug are determined based on the nature of the disease and the goal to be achieved. It is recommended to take the drug after meals so that the contents of the tablet do not harm the gastrointestinal tract. The tablet must be whole; if it is broken, the active substance may not reach the target due to the aggressive environment of the stomach.

For acute varicose veins, the number of tablets that need to be taken varies from 4 to 6. If we are talking about chronic varicose veins, then 2 tablets are enough. However, you should not decide on your own to take this drug; you should first consult your doctor. Only a specialist will be able to select the correct dosage, taking into account the characteristics of the body, medical history, severity of the current condition and other factors.

Venarus (diosmin+hesperidin) tablets 1000 mg No. 60

A country

Russia
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.

Compound

1 tablet contains: active ingredients: hesperidin (in terms of 100% substance) 100 mg, diosmin (in terms of 100% substance) 900 mg; excipients: microcrystalline cellulose 124 mg, sodium carboxymethyl starch (sodium starch glycolate) 54 mg, gelatin 62 mg, talc 12 mg, magnesium stearate 8 mg; excipients for the shell: hypromellose (hydroxypropyl methylcellulose) 41.4 mg, macrogol 6000 (polyethylene glycol 6000) 6.76 mg, sodium lauryl sulfate 0.2 mg, magnesium stearate 2.48 mg, titanium dioxide 7.88 mg, iron oxide red 0 .6 mg, yellow iron oxide 0.68 mg. Description Film-coated tablets of orange-pink color, biconvex, oblong in shape with rounded ends, scored. On a cross section, the kernel is grayish-yellow to brownish-gray in color. Release form: Film-coated tablets, 1000 mg. 9, 10 or 15 tablets in a blister pack made of polyvinyl chloride film and printed varnished aluminum foil. 1, 2, 3, 4, 5, 6, 7, 8, 9 contour cell packaging along with instructions for use are placed in a cardboard pack.

Pharmacological properties

Pharmacodynamics Venarus® has angioprotective and venotonic effects. Reduces the distensibility of veins, increases their tone and reduces venous stagnation; reduces permeability and fragility of capillaries and increases their resistance; improves microcirculation and lymphatic drainage. When used systematically, it reduces the severity of clinical manifestations of chronic venous insufficiency of the lower extremities of an organic and functional nature. The optimal dose-effect ratio is observed when taking 1000 mg per day. Pharmacokinetics The main excretion of the drug occurs through the intestines. On average, about 14% of the dose taken is excreted through the kidneys. The half-life is 11 hours. The drug Venarus® undergoes active metabolism, which is confirmed by the presence of phenolic acids in the urine.

Indications for use

Venarus® is indicated for the treatment of symptoms of chronic venous diseases (elimination and relief of symptoms). Treatment of symptoms of venous-lymphatic insufficiency: spasms of the lower extremities; feeling of heaviness and fullness in the legs; pain; "tired" legs. Treatment of manifestations of venous-lymphatic insufficiency: swelling of the lower extremities; trophic changes in the skin and subcutaneous tissue; venous trophic ulcers. Symptomatic treatment of acute and chronic hemorrhoids.

Contraindications

Hypersensitivity to the active components or excipients included in the drug. It is not recommended for women to take the drug during breastfeeding. Use during pregnancy and breastfeeding Pregnancy Experiments on animals did not reveal teratogenic effects. To date, there have been no reports of any side effects when using the drug by pregnant women. Breastfeeding period Due to the lack of data regarding the excretion of the drug in breast milk, it is not recommended for women to take the drug during breastfeeding. Effect on reproductive function Reproductive toxicity studies have shown no effect on reproductive function in rats of either sex.

Mode of application

Inside. The recommended dose for venous-lymphatic insufficiency is 1 tablet per day, preferably in the morning, during meals. The score on the tablet is intended solely for scoring purposes to make it easier to swallow. The duration of treatment can be several months (up to 12 months). In case of recurrence of symptoms, on the recommendation of a doctor, the course of treatment can be repeated. The recommended dose for acute hemorrhoids is 3 tablets per day (1 tablet in the morning, afternoon and evening) for 4 days, then 2 tablets per day (1 tablet in the morning and evening) for the next 3 days. The recommended dose for chronic hemorrhoids is 1 tablet per day.

Side effect

The frequency of adverse reactions is presented as follows: very often (≥1/10 cases), often (≥1/100 and From the central nervous system: rarely - dizziness, headache, general malaise. From the gastrointestinal tract: often - diarrhea, dyspepsia, nausea, vomiting; infrequently - colitis; frequency unknown - abdominal pain. From the skin: rarely - rash, itching, urticaria; frequency unknown - isolated swelling of the face, lips, eyelids, in exceptional cases angioedema. If any of the adverse reactions indicated in the instructions get worse, or you notice other adverse reactions not listed in the instructions, inform your doctor.

Overdose

No cases of overdose have been described. In case of drug overdose, seek medical help immediately.

Interaction

Not noted. You should inform your doctor about all medications you are taking.

special instructions

Before you start taking Venarus®, it is recommended to consult your doctor. In case of exacerbation of hemorrhoids, the use of Venarus® does not replace the specific treatment of other anal disorders. The duration of treatment should not exceed the periods specified in the section “Method of administration and dosage”. If the symptoms do not disappear after the recommended course of therapy, you should be examined by a proctologist, who will select further therapy. In the presence of venous circulation disorders, the maximum effect of treatment is ensured by combining therapy with a healthy (balanced) lifestyle: it is advisable to avoid long exposure to the sun, long periods of standing, and it is also recommended to reduce excess body weight. Walking and, in some cases, wearing special stockings helps improve blood circulation. Contact your doctor immediately if your condition worsens or does not improve during treatment. Effect on the ability to drive vehicles and machinery No effect.

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