From this article you will learn:
- What does Solcoseryl ointment help with?
- indications and regimens for use,
- application in cosmetology against wrinkles.
The article was written by a specialist with higher medical education.
Solcoseryl ointment is a preparation containing deproteinized dialysate from the blood of calves, which is an effective stimulator of healing of skin lesions and the red border of the lips. Here you need to pay attention to the fact that the drug is intended for application only to those wounds that do not have wet discharge. If the wound surface is wet or has discharge, in this case only Solcoseryl in gel form should be used.
The drug is registered as a “medicine” and is intended exclusively for external use. The drug is produced by pharma (Switzerland) and has no age restrictions, and is also not contraindicated for use in lactating and pregnant women. The latter indicates a high safety profile and a low risk of developing allergies. The ointment is a homogeneous white fatty mass, which has a characteristic smell of petroleum jelly and meat broth (the latter is associated with production technology).
Solcoseryl ointment: photo of the drug
Compound
The solution for injection contains 42.5 mg/ml hemoderivate (extract) from calf blood as an active substance and water for injection (Aqua pro injectionibus) as an auxiliary component.
One gram of eye gel contains 8.3 g of active substance and auxiliary ingredients: sodium carboxymethyl cellulose (Sodium carboxymethyl cellulose), sorbitol (Sorbitol), water for injection (Aqua pro injectionibus), benzalkonium chloride (Benzalkonii chloridum).
One gram ointment contains 2.07 mg of active substance and a number of auxiliary components: methyl parahydroxybenzoate (E 218; Methyl parahydroxybenzoate), propyl parahydroxybenzoate (E 216; Propyl parahydroxybenzoate), cetyl alcohol (Cetyl spiritus), cholesterol (Cholesterol), white petroleum jelly ( Vaselinum album), water for injection (Aqua pro injectionibus).
One gram of jelly contains 4.15 mg of active substance and a number of auxiliary components: methyl parahydroxybenzoate (E 218; Methyl parahydroxybenzoate), propyl parahydroxybenzoate (E 216; Propyl parahydroxybenzoate), propylene glycol (Propylene glycol), carboxymethyl cellulose sodium salt (Sodium carboxymethyl cellulose), water for injection (Aqua pro injectionibus), calcium lactate pentahydrate (Calcii lactas pentahydrate).
Which is cheaper: Actovegin or Solcoseryl
Actovegin is a complete analogue of Solcoseryl. Its active ingredient is deproteinized calf blood dialysate. The release forms of Actovegin do not differ from those in which Solcoseryl can be found. Tablets and ampoules for intravenous administration are prescribed for the same indications. Actovegin is a prescription drug, like Solcoseryl. Therefore, they can be considered as the same substance, sold under different names. This means that when one of them is not available in the pharmacy, the pharmacist has every right to offer an analogue as a replacement. However, when comparing price categories, Solcoseryl should be given preference, because its cost is lower than Actovegina.
pharmachologic effect
Solcoseryl is a medicine that affects mainly metabolic processes in tissues. They activate tissue metabolic processes , improve trophism and stimulate tissue repair and when exposed to damaging factors.
Solcoseryl in injection form belongs to the pharmacotherapeutic group “ Hemodialysates and hemofiltrates ”, ointment and jelly - to the category of drugs used to treat wounds and ulcers (including poorly healing ones), gel - to the category of drugs used to treat ophthalmological diseases .
Pharmacodynamics and pharmacokinetics
The main component of Solcoseryl preparations are fractions of the blood of calves with natural low-molecular substances included in their composition, the molecular weight of which does not exceed 5 thousand daltons.
To date, its properties have only been partially studied. In vitro tests, as well as preclinical and clinical studies, have shown that calf blood extract:
- promotes the restoration and/or maintenance of aerobic metabolism and oxidative phosphorylation processes, and also ensures the replenishment of cells that do not receive sufficient nutrition with high-energy phosphates;
- in vitro enhances the utilization of oxygen and activates the transport of glucose into tissues and cells hypoxia and ;
- helps improve repair and regeneration processes in damaged tissues that do not receive sufficient nutrition;
- prevents the development or reduces the severity of secondary degradation and pathological changes in reversibly damaged cells and cellular systems ;
- in in vitro models activates collagen synthesis ;
- has a stimulating effect on the proliferation (reproduction) of cells and their migration (in in vitro models).
Thus, Solcoseryl protects tissues that are in a state of oxygen starvation and nutritional deficiency, and accelerates the processes of their restoration and healing.
Solcoseryl eye gel is a dosage form that was developed specifically for the treatment of lesions with troma of the cornea .
The gel-like consistency of the product ensures its uniform distribution on the cornea , and good adhesive properties allow it to remain on it for a long period of time. The use of eye gel accelerates the restoration of damaged tissues and prevents scarring.
The rate and extent of absorption, distribution, as well as the rate and route of elimination of the active substance from the patient’s body cannot be determined using conventional pharmacokinetic methods, since protein-free calf blood extract has pharmacodynamic effects that are characteristic of molecules with different chemical and physical properties.
In the process of studying the pharmacokinetic characteristics of Solcoseryl solution in animals, it was found that after a bolus injection, the effect of the drug develops within half an hour. The effect lasts for three hours after administration of the solution.
Solcoseryl ointment: instructions and application diagram
Pharmacological action of the drug - as we said above: the active substance of the ointment is deproteinized (devoid of protein) hemodialysate, which contains a spectrum of low-molecular components of cell mass and blood serum of dairy calves. Clinical studies have shown that thanks to this composition, Solcoseryl ointment has a wound-healing, regenerating, antihypoxic, membrane-stabilizing, angioprotective, and cytoprotective effect on damaged tissues.
In simple terms, this means that the drug has the following properties -
- accelerates wound healing (by about 30%),
- stimulates the proliferation of fibroblasts responsible for collagen synthesis,
- stimulates collagen synthesis in young growing tissues,
- activates metabolic processes in cells (increases oxygen consumption by cells, stimulates the transport of glucose into cells), which together allows damaged cells of the body to regenerate and recover faster.
Solcoseryl ointment: official instructions for use (download in PDF)
Scheme and features of application –
Solcoseryl ointment should be applied in a thin layer directly to the wound surface 2-3 times a day. Before applying the ointment, the wound must be treated with an antiseptic solution using a clean gauze swab moistened with an antiseptic solution. After this, you need to wait until the wound dries and apply ointment. As antiseptics, you can use 3% hydrogen peroxide or antiseptic solutions -
- Chlorhexidine solution,
- Miramistin solution.
Important : remember that you should not apply the ointment to infected wounds, as well as fresh wounds with wet discharge! For wet wounds, Solcoseryl gel can be used, and after the wound dries and becomes covered with granulations or crusts, you can already switch to the ointment form of Solcoseryl. The latter, in addition, contains fatty components that will form a protective film on the wound surface (24stoma.ru).
After applying the ointment (if necessary), the wound can be covered with a gauze bandage. The use of the ointment should continue until its complete epithelization. If the healing of the wound has occurred with the formation of scar tissue, then in order to reduce the scar and make it more elastic, it makes sense to immediately start using a special cream for scars and scars.
Indications for use
Solcoseryl injections: what are they for and what groups of patients are they prescribed for?
Solcoseryl in ampoules is indicated for patients who have been diagnosed with occlusive peripheral artery disease of the third or fourth degree according to the Fontaine classification and who have contraindications or intolerance to other vasoactive drugs .
It is also prescribed to patients with chronic venous insufficiency , which is accompanied by the formation of treatment-resistant trophic ulcers , as well as to patients with disorders of cerebral metabolism .
What is Solcoseryl ointment and jelly for?
The use of ointment and jelly is advisable for the treatment of minor injuries (for example, abrasions or cuts), frostbite, first and second degree burns (thermal or solar), difficult-to-heal wounds (for example, trophic skin disorders of venous etiology or bedsores ).
Indications for use of eye gel
Solcoseryl eye gel is recommended:
- for the treatment of mechanical injuries and erosive damage to the cornea and conjunctiva ;
- to accelerate the healing processes of postoperative scars in the postoperative period (for example, after a cornea transplant , surgery to remove a cloudy lens , surgical treatment of glaucoma , etc.);
- for the treatment of burns of the cornea of various origins (thermal, chemical or radiation);
- for the treatment of ulcerative lesions of the cornea and keratitis of various etiologies ;
- for dystrophic lesions of the cornea of various etiologies, including neuroparalytic keratitis , endothelial-epithelial dystrophy ( bullous keratopathy ), etc.;
- for the treatment of corneal xerophthalmia with lagofatalmos (non-closure of the palpebral fissure);
- to improve the tolerability of contact lenses and reduce the time of adaptation to them.
Indications for use of Solcoseryl dragees
The drug in the form of pills is taken to treat trophic and radiation ulcers , bedsores , gangrene , and chronic venous insufficiency . They are also prescribed to patients with gastric and duodenal ulcers and patients who require skin and/or corneal transplantation .
How to use the ointment
Instructions for use of solcoseryl include the following recommendations:
- the ointment is applied only topically directly to the wound, covering those areas where the healing process has begun;
- the wound surface is pre-cleaned with disinfectant solutions, since the ointment does not contain antibacterial components;
- in case of purulent infection, cleanse from exudate and dead tissue;
- ointment is prescribed for the treatment of injuries with clear signs of healing;
- apply solcoseryl to the surface of the wound in the morning and evening, apply a bandage if necessary;
- Treatment should be continued until the wound is completely scarred.
The use of solcoseryl is determined by the type of pathology. Thus, for chronic trophic ulcers, it is recommended to treat the inner surface with solcoseryl gel, and the outer edges of the wound with ointment 2 times a day for 3 weeks. For diabetic feet without exudate, the ointment is applied twice a day for 2 months.
In proctology, solcoseryl ointment has only positive reviews from patients. This is due to the fact that the drug promotes rapid tissue healing and stimulates blood supply in damaged vessels. However, the ointment can be used only for external forms of hemorrhoids, which are not accompanied by the formation of anal fissures (in this case, it is more appropriate to prescribe solcoseryl gel). The drug is applied to hemorrhoids 4-5 times a day for a week.
The nuances of using the ointment:
- The drug should not be used by pregnant women or during lactation, since appropriate clinical trials have not been conducted;
- if pain appears in the wound area, redness of the skin around the injury, exudate, or elevated body temperature, you should consult your doctor;
- If there are no signs of wound healing within 2-3 weeks of use, you should immediately consult a doctor, as this may indicate a benign or malignant wound process.
Contraindications
Administration of the solution is contraindicated in patients with known hypersensitivity to calf blood dialysates. The solution is also contraindicated for atopy and for persons allergic to milk .
Since the ointment, jelly and solution contain derivatives of parahydroxybenzoic acid , which are used as preservatives, as well as trace concentrations of benzoic acid in free form, it is not used in the presence of allergic reactions to the above substances.
With caution, ointment and jelly are prescribed to persons with a predisposition to allergic reactions .
A contraindication to the use of eye gel is hypersensitivity to its components. Since the eye gel can cause temporary visual impairment, you should not drive a car or operate potentially dangerous machinery for half an hour after its use.
The uniqueness of the composition of solcoseryl
The ointment has a uniform, greasy texture; the color can vary from deep white to yellow, with a characteristic odor of broth and petroleum jelly.
The active components of solcoseryl include deproteinized (removal of proteins) hemoderivat from the blood of 3-month-old calves at a concentration of 2.07 mg/g. Auxiliary components are represented by methyl parahydroxybenzoate and propyl parahydroxybenzoate (preservatives), palmitic alcohol (emulsifier), white petrolatum (ointment base), water for injection (dissolution of dry dialysate).
An analogue of the drug is Actovegin ointment. These drugs appeared on the pharmaceutical market almost simultaneously and differ only in the manufacturer and price.
The main active ingredient of solcoseryl is a deproteinized hemoderivat, which is obtained by dialysis and subsequent ultrafiltration. During the production process, high molecular weight proteins are removed (deproteinization). This is a complex compound that includes natural low-molecular substances with a molecular weight of up to 5000 Da.
Such a unique composition cannot be reproduced in laboratory conditions. Basically, these are electrolytes, amino acids, nucleotides, nucleosides. The effectiveness of only some of these substances has been described and proven from a pharmacological point of view. However, in vitro tests have proven the effectiveness of solcoseryl in the treatment of damaged tissues and wound surfaces.
Side effects
Administration of Solcoseryl IV or IM in very rare cases (their frequency does not exceed 0.1%) provokes the development of allergic or anaphylactic reactions , which are most likely caused by class E immunoglobulins .
If body temperature rises, urticaria , swelling and hyperemia at the site of drug administration, the use of Solcoseryl is stopped, and symptomatic treatment will be prescribed to eliminate the symptoms that appear.
Since the solution contains potassium, its administration may cause pain at the injection site.
When using Solcoseryl cream, a short-term burning sensation may be felt at the site of application. Discontinuation of the drug is required only in cases where the unpleasant sensation does not disappear for a long period of time.
In isolated cases, the use of jelly and ointment can cause the development of allergic reactions . If allergy symptoms , the use of these products should be discontinued.
Toxicological studies of Solcoseryl eye gel have shown the high safety of this drug when used for its intended purpose in accordance with the instructions.
After instillation of the product, a short-term burning sensation and mild irritation may be observed, which are not reasons for stopping treatment. Repeated instillation in rare cases provokes the development of allergic reactions (a similar effect is also observed during treatment with other ophthalmic drugs for topical use).
Instructions for use of Solcoseryl (Method and dosage)
Solution for injection: instructions for use
In cases where the patient's condition allows, the drug is recommended to be used in the form of an injection solution diluted at least 50:50 with saline or glucose solution .
Solcoseryl in ampoules is intended for slow administration in the form of intravenous injections or infusions. If intravenous administration is not possible, the drug can be injected into the muscle.
Since the drug in its pure form is a hypertonic solution, it should be administered slowly.
For intravenous infusion, the drug should be pre-diluted with 0.25 l of 0.9% NaCl solution or 5% glucose solution . Solcoseryl solution is administered intravenously by drip. The rate of administration depends on the hemodynamic status of the patient.
Patients with occlusive disease of peripheral arteries of the third or fourth degree according to the Fontaine classification are shown daily injection into a vein of 0.85 g (or 20 ml of undiluted solution) Solcoseryl.
The duration of use is usually up to four weeks and depends on the clinical situation.
Patients with chronic venous insufficiency , which is accompanied by the formation of treatment-resistant trophic ulcers , are indicated for intravenous administration of 0.425 g (or 10 ml of undiluted solution) Solcoseryl three times a week.
The duration of the course of treatment should not exceed four weeks (it is determined depending on the nature of the disease).
To prevent the appearance of peripheral “venous” edema , therapy is supplemented by applying a pressure bandage using an elastic bandage. If the patient has skin trophic disorders, treatment is carried out by combining injections or infusions of Solcoseryl solution with the use of jelly, and then ointment.
Patients who have suffered ischemic or hemorrhagic stroke are prescribed daily intravenous administration of 0.425 or 0.85 g of Solcoseryl (10 or 20 ml of undiluted solution) as the main course. The duration of the main course is 10 days.
Further treatment involves daily administration of 85 mg (or 2 ml of undiluted solution) Solcoseryl for one month.
In severe forms of brain contusions, daily injection of 1000 mg of Solcoseryl into a vein (corresponding to 23-24 ml of undiluted solution) is prescribed for 5 days.
The drug is administered intramuscularly undiluted at a dose of 2 ml/day.
Solcoseryl jelly and ointment: instructions for use
Cream and ointment are intended for application directly to the wound surface. Before using these dosage forms, the wound is first cleaned using a disinfectant solution.
Patients with trophic ulcers , as well as in cases of purulent infection of wounds , require preliminary surgical treatment before starting treatment.
When using jelly and ointment for frostbite , as well as for the treatment of ulcers and skin injuries , it is important to remember that only sterile dressings should be used to treat damaged areas.
The gel is intended for application to fresh (including wet) wounds and weeping ulcers . The product is applied in a thin layer to a previously cleaned wound surface two or three times a day.
To treat areas where epithelization has begun, the use of ointment is indicated. The use of jelly is advisable until pronounced granulation tissue begins to form on the damaged surface of the skin and the wound begins to dry out.
The ointment is used primarily for the treatment of dry (without weeping) wounds . The product is applied in a thin layer to a previously cleaned wound surface once or twice a day. If necessary, cover the treated surface with a bandage.
The course of treatment with the drug in this dosage form continues until the wound heals and is completely healed with elastic tissue.
For patients with severe trophic damage to the skin and soft tissues, it is recommended to combine jelly and ointment with the injection form of Solcoseryl.
Experience with the use of jelly and ointment for children is limited.
The drug does not have such release forms as suppositories. However, in the complex therapy of chronic colitis (inflammation of the colon), microenemas with Solcoseryl jelly are often prescribed.
Before use, the jelly contained in the tube (all 20 g) is added to 30 ml of warm water and after the enema procedure, which is carried out to cleanse the intestines , it is administered daily for 10 days.
Solcoseryl eye gel: instructions for use
Unless otherwise instructed by the attending physician, the eye gel is instilled into the conjunctival cavity , one drop three or four times a day. It is recommended to use the product daily until complete recovery.
In particularly difficult cases, eye ointment can be used one drop per hour. If the patient is simultaneously prescribed eye drops and Solcoseryl eye gel, the gel should be applied approximately half an hour after the drops.
During the period of adaptation to contact lenses, the drug is instilled into the conjunctival cavity immediately before installing the lenses and immediately after removing them.
Dragee Solcoseryl: instructions for use
The instructions recommend taking 100 mg tablets three times a day.
How to inject Solcoseryl for gastritis
Gastritis is a disease of the gastric mucosa that can occur for various reasons. Solcoseryl ampoules will not become the main drug used in the treatment of gastritis, but it can speed up the healing process, while the prescribed therapy will relieve the patient of the source of the problem.
The gastric mucosa can become inflamed not only as a result of poor nutrition, but also as a result of infection with gastrointestinal infections. The attending physician will first conduct an examination and evaluate the test results, which will allow him to prescribe effective therapy. Solcoseryl will be used as an addition to the main treatment, as it will help the stomach tissues to regenerate faster, ulcers to heal, and inflammation to disappear.
special instructions
Studies regarding the safety of using Solcoseryl solution for the treatment of children have not been conducted, therefore the drug is not recommended for the treatment of children under the age of 18 years.
Experience in treating children with the use of eye gel and topical dosage forms of the drug is also limited.
Solcoseryl in ampoules should be administered separately from other drugs (it is especially incompatible with phytoextracts). The exceptions are isotonic 0.9% NaCl solution and 5% glucose solution . It is also not recommended to dilute the product in potassium-containing solutions for infusion.
Eye gels are characterized by the ability to stick to contact lenses, so it is recommended to stop wearing lenses during treatment with the drug.
If allergic reactions associated with the use of the drug, you should immediately report them to your doctor. If the drug is used to treat an infectious disease of the cornea , therapy is supplemented with the prescription of appropriate antimicrobial agents .
Avoid contact of the gel with soft contact lenses as it may discolor them.
If necessary, treatment with Solcoseryl can be supplemented with antibacterial , vasodilating and other drugs.
Solcoseryl in cosmetology: for the face, hands, rough elbows and heels, for the skin around the eyes
In medicine, Solcoseryl preparations are used to accelerate the healing of damaged skin; in home cosmetology, they are used as a remedy for acne, stretch marks, and wrinkles. They are used to soften the skin, increase its turgor, improve complexion and eliminate acne .
In cosmetology, the ointment can be used as a stand-alone product (it is applied pointwise to problem areas, in the form of a mask once a week before bedtime and two to three times a week on the skin around the eyes), or in combination with other products, in particular with the drug Dimexide . Let's look at how to use these medications together.
For the face, Dimexide and Solcoseryl are used as follows: on the face, neck and décolleté, previously cleaned with peeling agents (you can also do alkaline peeling using tar soap, salt and soda), apply a solution of Dimexide with water, prepared in a ratio of 1:10 (enough dilute 5 ml (teaspoon) of Dimexide in 50 ml of water); Before the product has time to be absorbed, Solcoseryl ointment is applied to it in a thick layer.
If the gel is used in cosmetology, then the mask should be periodically sprayed with thermal water (you can also use regular water through a spray bottle). The mask is left on the face for about half an hour to an hour, then washed off and a light hypoallergenic cream is applied to the skin.
According to women who have tried this mask recipe on themselves, Solcoseryl ointment is more comfortable for the face than gel (after application, you don’t have to wash it off, just remove the residue with a napkin). In addition, it is not recommended to use a gel mask more than once a month.
Used as a remedy for wrinkles around the eyes, Solcoseryl ointment has proven itself to be a very effective remedy. Applying it like a regular cream, within a week you can see that the number of wrinkles and wrinkles has decreased, the skin has tightened and smoothed, and its color has become fresher and healthier.
Dimexide and Solcoseryl are no less effective against wrinkles, and perhaps even more effective. This is due to the ability of Dimexide to enhance the penetration of the active substance of drugs deep into the tissue. After using these products in combination, skin irregularities and imperfections disappear, and the effect of the mask is comparable to the effect of Botox .
The gel and ointment can also be used to soften rough skin on the elbows and heels. It is best to apply them to problem areas before bed.
What is Solcoseryl ointment used for?
The drug is based on deproteinized dialysate obtained through special processing from the blood of calves. This substance is often used in medicine in countries such as China, Korea, and the entire CIS. It has proven itself to be an effective remedy that can:
- enrich tissue cells damaged due to hypoxia with oxygen and glucose;
- start tissue repair processes;
- activate healthy cell division processes;
- increases the level of energy produced by cells;
- protects the skin from external damage by forming a film on its surface;
- triggers the production of collagen by tissues.
Based on the activity of the drug, the drug can be used for:
- frostbite;
- psoriasis;
- anal ring cracks;
- cuts;
- abrasions;
- scratches;
- bedsores;
- acne marks;
- dermatitis;
First of all, to achieve the best effect, it is necessary to start therapy in the early stages of the problem.
Analogues of Solcoseryl
Level 4 ATX code matches:
Badyaga Forte
Badyaga
Rogaine
Capsiol
Vulnuzan
Skin cap
Petrolatum
Generolon
Alerana
Apilak
Tsinocap
Silocast
Analogs of Solcoseryl: Aekol , Acerbin , Bepanten , Shostakovsky balm , Vundehil , Depantol , Contractubex , Pantekrem , Pantexol Yadran , Panthenol , Pantestin , Hepiderm Plus , Echinatsin Madaus .
Reviews of Solcoseryl
Almost all reviews left on the forums about injections, eye gel, jelly and Solcoseryl ointment are positive. Rare negative reviews are due largely to the fact that the drug provoked allergic reactions associated with intolerance to its active component.
Reviews of Solcoseryl gel and the drug in the form of an ointment allow us to conclude that these drugs effectively cope not only with minor scratches and minor burns, but also help cure difficult-to-heal wounds and ulcers .
The average rating of a drug on sites where people share their impressions of certain drugs is 4.8 on a 5-point scale.
The effectiveness of the ointment in cosmetology is also highly appreciated. Reviews of Solcoseryl ointment for the face indicate that this is truly an indispensable product for those who want to quickly get rid of wrinkles, acne, and simply improve the color and tone of the skin.
Gel is no less effective against wrinkles, but cosmetologists believe that it should not be used as part of masks too often (optimally - once a month). The ointment can be used as a regular cream.
The effectiveness of Solcoseryl against wrinkles increases when combined with Dimexide, which is due to the latter’s ability to improve the penetration of the active substance deeper into the skin.
Gel Solcoseryl: reviews
An important condition for achieving a good treatment result is the correct choice of the form of the drug Solcoseryl - this can be in the form of a gel, ointment or dental adhesive paste.
The effect of the gel will be noticeable specifically on wet wounds, and consists in accelerating the formation of granulation tissue by about 30%. You will not notice the effect of the gel when used on dry wounds, and it is unlikely that you will be able to leave a good review of the product after this. Solcoseryl gel will have a good pronounced effect and will accelerate the healing of wounds and ulcer erosions, unless, of course, they are related to tumor-like lesions. The latter must be especially borne in mind, because if the erosion or ulcer has existed for a long time, or there is no effect when using Solcoseryl, then these are signals indicating that this lesion of the mucous membrane/skin is related to tumor-like tissue damage.
Another important point is applying the drug to infected wounds. For the drug to give a good result, there must be no infection in the wound. Purulent wounds, as well as wounds with torn edges, first require primary surgical treatment and drug therapy. Reviews for Solcoseryl gel will be positive only if you carefully follow all recommendations for its use. Failure to follow the recommendations for use, especially with regard to infected wounds, can, on the contrary, lead to increased inflammation.
Solcoseryl anti-wrinkle gel in cosmetology: reviews
Some patients persistently try to use Solcoseryl gel for the face to get rid of wrinkles. The logic here is clear - since the drug increases proliferation (reproduction) and activity of fibroblasts, then its use should seem to lead to an increase in collagen production. Unfortunately for patients, it must be noted that none of the forms of solcoseryl work on intact skin.
Therefore, Solcoseryl ointment or gel is not used in cosmetology, and they are effective only for accelerating the healing of skin damage, including after surgical and cosmetic interventions. To stimulate collagen production in aging skin, it is better to use retinoid-based products, and an even faster effect is achieved by a hardware technique that uses fractional lasers. These techniques do have proven evidence of increasing collagen in the skin (see links above for arguments and clinical studies).
If you are interested in a cream that can improve skin regeneration and keep it moisturized, especially in winter, one of the best options would be to use Bepanthen for Dry Skin cream. It contains not only dexpanthenol (a precursor to vitamin B5, which enhances skin regeneration), but also moisturizing components such as the emollient “lanolin”, as well as D, L-pantolactone. I recommend this product because... I myself use it 2 times a day in the winter and see its effectiveness from personal experience. It can even be applied to the moving parts of the eyelids. A 100 ml tube costs only about 950 rubles.
Solcoseryl price, where to buy
How much does Solcoseryl cost in Ukraine?
The average price of Solcoseryl in ampoules in Ukrainian pharmacies is from 265 to 515 UAH (depending on the volume of ampoules and their number in the package). The price of Solcoseryl ointment in Ukraine is 57-60 UAH. You can buy jelly for an average of 52 UAH. Eye cream costs on average from 60 to 74 UAH.
Cost of the drug in Russia
The price for Solcoseryl injections in Russian pharmacies varies from 400 to 1300 rubles (depending on the volume of ampoules and their number in the package). The price of Solcoseryl gel (which can be used as an anti-wrinkle gel) is 180-200 rubles. The price of the eye gel is 290-325 rubles. Pharmacies provide information on the price of tablets upon request.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
LuxPharma* special offer
- Solcoseryl ointment tube 20g
RUB 2,170 order - Solcoseryl dental adhesive paste 5g
RUR 2,480 order
- Solcoseryl injections/solution for injection (Solcoseryl ampoules) 42.5 mg/ml 5 ml No. 5
RUR 4,780 order
ZdravCity
- Solcoseryl Dent adhesive paste. 5 gLEGASY PHARMACEUTICALS
RUR 2,480 order
Pharmacy Dialogue
- Solcoseryl paste (dental, tube 5% 5g)Legacy
RUB 2,470 order
- Solcoseryl gel (tube 20g)Legacy
RUB 2,633 order
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Pharmacy24
- Solcoseryl 5 ml No. 5 injection solution Legacy Pharmaceuticals, Sweetseland GmbH, Switzerland
515 UAH. order - Solcoseryl 4.15 mg/g 20 g gel Legacy Pharmaceuticals, Sweetseland GmbH, Switzerland
164 UAH order
- Solcoseryl 2.07 mg/g 20 g ointment Legacy Pharmaceuticals, Sweetseland GmbH, Switzerland
136 UAH order
- Solcoseryl 42.5 mg/ml 2 ml N25 injection solution Legacy Pharmaceuticals, Sweetsland GmbH, Switzerland
919 UAH. order
- Solcoseryl 5% 5 g paste
176 UAH order
PaniPharmacy
- Solcoseryl ampoule Solcoseryl injection solution ampoules 2ml No. 25 Switzerland, Legacy Pharmaceuticals Switzerland
950 UAH order
- Solcoseryl gel Solcoseryl jelly 10% 20g Switzerland, Legacy Pharmaceuticals Switzerland
161 UAH order
- Solcoseryl injection solution ampoules 5 ml No. 5 Australia, Legacy Pharmaceuticals Sweetsland GmbH
476 UAH. order
- Solcoseryl ampoule Solcoseryl injection solution ampoules 5ml No. 5 Switzerland, Legacy Pharmaceuticals Switzerland
545 UAH. order
- Solcoseryl jelly 10% 20g Australia, Valeant Pharmaceuticals Sweetsland
181 UAH order
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Solcoseryl ointment – price in the pharmacy, composition analysis
You will not like the cost of this drug. If 1-2 years ago it could be bought for 500-700 rubles, now the price for Solcoseryl ointment in a pharmacy will be from 2600 to 3000 rubles. This cost is indicated as of mid-October 2021 (and the drug is not available in many pharmacies), but below we will also talk about cheaper indirect analogues of this drug. Solcoseryl in the form of an ointment is available in aluminum tubes of 20 g and is sold in pharmacies without a prescription.
Solcoseryl ointment: composition
Active substances (in 1 g of ointment) – → deproteinized dialysate from the blood of healthy dairy calves (in terms of dry matter). | 2.07 mg |
Excipients - cholesterol, cetyl alcohol, white petrolatum, distilled water, as well as preservatives - methyl parahydroxybenzoate (E 218) and propyl parahydroxybenzoate (E 216). |
Composition analysis - the main and only active component of this drug is a deproteinized dialysate from the blood of dairy calves. This substance is very rich in low molecular weight organic compounds - amino acids, glycolipids, as well as oligopeptides and nucleosides. All these components, acting on damaged tissues, accelerate the healing processes in them. Studies have shown that the rate of regeneration when using this drug increases by approximately 30%.
Due to the large amount of organic components in the composition, the use of preservatives is also required. These are E 218 and E 216 (methyl parahydroxybenzoate and propyl parahydroxybenzoate), which can be classified as parabens. You need to pay attention to this point if you have allergic reactions to cosmetics or oral hygiene products, or if you have increased allergies in general.
Solcoseryl: analogues
It is impossible to find analogues for Solcoseryl ointment in Russian pharmacies, because the only drug with a similar composition, Actovegin ointment, is no longer imported into Russia. But there are several drugs with a completely different composition that can also speed up the healing of skin damage. We are talking about scratches, abrasions, cracks, cuts, wounds, minor burns, bedsores, etc. If there are wounds, a doctor should prescribe such drugs (after examining the wound and determining the risk of infection).
Among drugs for external use that accelerate wound healing (drugs from the “regeneration stimulants” group), we can recommend the following drugs:
- OLAZOL – the drug is made on the basis of chloramphenicol, sea buckthorn oil and benzocaine (anesthetic), and it is produced in a convenient aerosol form. It not only accelerates wound healing, but also has an antimicrobial and analgesic effect (hence Olazol is also suitable for wet, infected wounds). In turn, Solcoseryl ointment does not have an antimicrobial effect, and therefore it can only be applied to clean, dry wounds. The cost of the drug is only about 220 rubles.
- BEPANTEN –This line of drugs contains 5% dexpanthenol - a precursor of vitamin B5, which stimulates skin regeneration. If you have an uninfected dry wound under a crust (without a wet discharge), then any of the following forms of the drug will suit you - Bepanten cream or Bepanten plus cream. These drugs are usually applied 2 times a day - rub in with gentle massaging movements.
But if we are talking about wet wounds, which always have a risk of infection, only Bepanten Plus cream is suitable for you (the same version of the drug is preferable for cuts, scratches and abrasions). The cream contains dexpanthenol + antiseptic chlorhexidine 0.5%, which provides a pronounced antimicrobial effect. On wet wounds, the drug is applied on turundas under a bandage - 2 or more times a day, but shallow cuts and scratches can be treated openly. The cost of the Bepanten line of drugs ranges from 400 to 470 rubles per 30 g tube (there are also tubes of 50 and 100 g).
- METHYLURACIL ointment - this drug is also capable of slightly accelerating the regeneration processes of wounds on the skin, but much weaker in comparison with Solcoseryl ointment.
The only advantage of the drug is its very low price (a 25 g tube costs only 50 to 100 rubles). For dry, uninfected wounds, apply and rub in the product using gentle movements. If we are talking about moist, uninfected wounds, then the drug is applied on turundas under a bandage. The frequency of changing dressings will depend on the depth/area of the wound surface, the amount of wet discharge from the wound, etc. Methyluracil ointment does not have an antiseptic effect and therefore there is a risk of suppuration of wet wounds when using it (to reduce the risk of suppuration, it is necessary to pre-treat the wound with antiseptics).