Dysbacteriosis when taking antibiotics


What is the medicine Acipol for?

Indications for use can be found in the instructions. But this does not mean that a person can determine for himself the advisability of using the drug. Before your appointment, it is recommended to consult with a specialist who can prescribe an individual treatment regimen.

The medication is prescribed for various types of inflammatory reactions in the intestinal area. Such reactions include: dysentery, salmonellosis, adenoviral infections. Acipol is also prescribed for colitis. This medicine is used to treat dysbiosis.

Other indications include the need for long-term antibacterial treatment. The medicine is often used by people with weak immune systems. Acipol has proven itself well in correcting the condition of babies who were born prematurely. The drug is given to correct the gastrointestinal tract. It is in infancy that children often experience gas formation and pain in the abdomen.

Live bacteria

> References

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1

- for dysbiosis

About Atsipol

* — UTI

1

— Feklisova L.V.
The use of lactose-containing probiotics: an assessment of the long-term use of Acipol in pediatric practice // Pediatrics. – 2007. – No. 2. – P. 123-127. 2
— Novokshonov A.A., Sokolova N.V., Berezhkova T.V., Sakharova A.A., Larina T.S.
Clinical effectiveness and impact on the intestinal microbiocenosis of the probiotic Acipol in the complex therapy of acute intestinal infections in children // Pediatrics. Journal named after G.N. Speransky. 2007. No. 2. 3
— Maev I.V., Ivashkina N.Yu., Samsonov A.A., Kazyulin A.N., Vyuchnova E.S., Shuster A.M., Martyanov V.A.
Possibilities for the prevention of idiopathic antibiotic-associated diarrhea in adults. //Russian Journal of Gastroenterology, Hepatology, Coloproctology. – 2009. – No. 2. 4
– Tselipanova E.E. Clinical and laboratory evaluation of the biological drug Acipol in children with respiratory pathology. Author's abstract. diss. Ph.D. honey. Sci. - M., 2001. - 24 p. — p.75-78.

Advantages

1

— Instructions for medical use
2
— L.V. Feklisova MONIKI im.
M.F.Vladimirsky. The use of lactose-containing probiotics: an assessment of the long-term use of Acipol in pediatric practice 3
- M.S. Savenkova, A.A. Afanasyeva Treatment of infections: antibacterial and probiotic effects.
pediatrics №1 | 2008 |S. 38 4
— A.A.
Novokshenov et al. The use of a domestic probiotic containing Lactobacillus acidophilus for the treatment of acute intestinal infections and other pathologies in children. Children's infections 2021, No. 1, P.33. 5
— Ivashkina N. Yu., Botina S. G. Original domestic probiotic acipol: molecular biological and metabolic characteristics // Russian Journal of Gastroenterology, Hepatology, Coloproctology.
- 2009. - No. 2. - p. 58-64. Feklisova L.V. The use of lactose-containing probiotics: an assessment of the long-term use of Acipol in pediatric practice // Pediatrics. – 2007. – No. 2. – P. 123-127. 6
— Instructions for medical use.
7
— Feklisova L.V.
The use of lactose-containing probiotics: an assessment of the long-term use of Acipol in pediatric practice // Pediatrics. – 2007. – No. 2. – P. 123-127. 8
— Feklisova L.V.
The use of lactose-containing probiotics: an assessment of the long-term use of Acipol in pediatric practice // Pediatrics. – 2007. – No. 2. – P. 123-127. 9
— Nikitina L.V., Kalutsky P.V., Lazarev A.I., Besedin A.V.
The effectiveness of the use of a probiotic (Acipol) in the complex therapy of chronic gastroduodenitis associated with H. Pylori in children //International Journal on Immunorehabilitation. - 2010. - T. 12. No. 2. - P. 10
- Kladova O. V., Ivashkina N. Yu., Shuster A. M., Martyanov V. A., Uchaikin V. F., Rusakova V. D. ., Donin I.M., Shevchenko N.N., Agafonova T.V., Glazunova L.V., Pronina L.A. Preventive and therapeutic effectiveness of Acipol for antibiotic-associated diarrhea in children //Children's infections.
– 2009. – No. 2. – P.44-47. 11
— Barmina O.S., Gorelov A.V., Usenko D.V., Ardatskaya M.D. Clinical and laboratory effectiveness of the multiprobiotic drug Acipol in the complex therapy of “invasive” acute intestinal infections in children // Infectious diseases. – 2009. – T.7, No. 1. – p.76-79.

Composition and effects

1

— Novikov Vasily Egorovich Pharmacological regulation of intestinal microbiocenosis // Clinical Reviews.
Pharmacol. and lek. therapy. 2009. No. 2
- Ivashkina N. Yu., Botina S. G. Original domestic probiotic acipol: molecular biological and metabolic characteristics // Russian Journal of Gastroenterology, Hepatology, Coloproctology.
- 2009. - No. 2. - p. 58-64. 3
— Oreshko L.S., Matveeva I.I., Ivanova O.I., Prokofieva N.A., Balagaeva M.S.
On the issue of the immunomodulatory effect of the drug Acipol in complex pathogenetic therapy in patients with celiac disease // Diseases of the digestive organs. – 2009.- No. 2.- P.63-65. 4
— Feklisova L.V.
The use of lactose-containing probiotics: an assessment of the long-term use of Acipol in pediatric practice // Pediatrics. – 2007. – No. 2. – P. 123-127. 5
— Ivashkina N. Yu., Botina S. G. Original domestic probiotic acipol: molecular biological and metabolic characteristics // Russian Journal of Gastroenterology, Hepatology, Coloproctology. - 2009. - No. 2. - p. 58-64. Feklisova L.V. The use of lactose-containing probiotics: an assessment of the long-term use of Acipol in pediatric practice // Pediatrics. – 2007. – No. 2. – P. 123-127.

Symptoms of dysbiosis

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— Atopy is one of the most common types of dermatosis, the manifestation of which is inflammation of the skin associated with an allergic reaction.

How to use the medicine

Only a specialist can establish a drug treatment regimen. Treatment options depend on the severity of the problem and how the disease progresses. The capsule does not need to be cracked, but swallowed whole and washed down with plenty of drinking water.

If the patient has an acute intestinal disease, then you need to drink 4 capsules per day 25 minutes before meals. The average duration of the treatment course is a week. It is not recommended to take longer than 10 days, while other probiotics are used for a long time. This is a significant advantage of the composition.

Patients claim that the capsules are very convenient and easy to take, they are not large in size.

Acipol

* For dysbacteriosis

1. According to IQUIA Solutions LLC data for January – December 2021. The average retail price for the drug Atsipol is 352 rubles 84 kopecks

2. O. V. Molochkova, O. V. Kladova, A. A. Novokshonov, N. L. Valts, Yu. V. Kompaniets, N. L. Grishkevich. Prevention of antibiotic-associated diarrhea in children with a lactose-containing probiotic. Children's infections 2021, No. 4, S 37-411

3. List of studies conducted:

Novokshenov A. A., Molochkova O. V. et al. The use of a domestic probiotic containing Lactobacillus acidophilus for the treatment of acute intestinal infections and other pathologies in children. Therapy issues. Children's infections 2021, No. 1. Kladova O. V. et al. Preventive and therapeutic effectiveness of Acipol for antibiotic-associated diarrhea in children // Children's infections. – 2009. – No. 2. – P.44-47. Maev I.V. et al. Possibilities for the prevention of idiopathic antibiotic-associated diarrhea in adults. //Russian Journal of Gastroenterology, Hepatology, Coloproctology. – 2009. – No. 2. – pp. 75-78. Novokshonov A.A., Sokolova N.V., Berezhkova T.V., Sakharova A.A. Clinical effectiveness of the probiotic “Acipol” in the complex therapy of acute intestinal infections of bacterial, viral and viral-bacterial etiology in children // Children's infections. – 2009. – No. 4. – P. 61-65. Barmina O.S., Gorelov A.V., Usenko D.V., Ardatskaya M.D. Clinical and laboratory effectiveness of the multiprobiotic drug Acipol in the complex therapy of “invasive” acute intestinal infections in children // Infectious diseases. – 2009. – T.7, No. 1. – p.76-79. Bulanova I.A. Rationale for the use of lactose-containing probiotics for acute watery diarrhea in young children. Abstract. diss. Ph.D. honey. Sci. - Arkhangelsk, 2008. - 24 p. Yurlova E.V., Grigorovich M.S., Chastoedova I.A. State of enzyme secretion function in acute intestinal infections in children against the background of probiotic correction // Questions of practical pediatrics. – 2011. – T. 6, No. 3. - With. 97–101 Feklisova L.V. The use of lactose-containing probiotics: an assessment of the long-term use of Acipol in pediatric practice // Pediatrics. – 2007. – No. 2. – P. 123-127. Oleinichenko E.V., Mitrokhin S.D., Nonikov V.E., Minaev V.I. The effectiveness of acipol in the prevention of intestinal dysbiosis during antibacterial therapy // Antibiotics and chemotherapy. – 1999. – No. 1. – P.23-25. Volodko N.A., Konstantinova A.V., Klimenko N.Yu. Comparative effectiveness of drugs with different effects on the intestinal biocenosis in patients with respiratory tuberculosis // International Journal on Immunorehabilitation. - 2010. - T. 12. No. 2. - P. 120-121. Tselipanova E.E., Shebekova V.M., Savitskaya K.I., Rusanova E.V., Matveevskaya N.S. Clinical and immunological effectiveness of Acipol in children with acute respiratory infection // Almanac of Clinical Medicine. - 2002. - No. 5. - P. 260-264. Savenkova M.S., Afanasyeva A.A. Treatment of infections: antibacterial and probiotic effects // Pediatrics. - 2008. - No. 1. - P. 38-40. Gordeets A.V., Piskunova S.L., Chernikova A.A. Optimization of ARVI therapy in children during an influenza pandemic // Children's infections. - 2011.- No. 4. -P.52-56. Kushnareva M.V., Dementyeva G.M., Feklisova L.V., Chernogor I.N. The influence of eubiotic drugs on local intestinal immunity in premature infants with infectious and inflammatory diseases. // Pediatrics. - 2003. - No. 3. - P. 11-14. Novikova V.P., Gurova M.M., Tsekh O.M. Complex treatment using probiotics based on lactobacilli in children with chronic gastroduodenitis in remission. Advanced medical technology. - St. Petersburg, 2010. - 24 p. Nikitina L.V., Kalutsky P.V., Lazarev A.I., Besedin A.V. The effectiveness of the use of a probiotic (Acipol) in the complex therapy of chronic gastroduodenitis associated with H. Pylori in children //International Journal on Immunorehabilitation. - 2010. - T. 12. No. 2. - P. 220b-220b. Revnova M. O. Efficacy of Acipol in the treatment of children with celiac disease // Pediatrics. Consilium medicum. – 2009. – No. 1. – p.58-59. Oreshko L.S., Matveeva I.I., Ivanova O.I., Prokofieva N.A., Balagaeva M.S. On the issue of the immunomodulatory effect of the drug Acipol in complex pathogenetic therapy in patients with celiac disease // Diseases of the digestive organs. – 2009.- No. 2.- P.63-65. Kryuchkova T.A. et al. Clinical effectiveness of the probiotic Acipol in children suffering from atopic deramatitis. // Scientific bulletins of BelSU. Series: Medicine. Pharmacy. 2012. No. 22 (141). Shuster A.M. et al. Possibilities for optimizing the use of probiotics in clinical practice using the example of the domestic drug Acipol®. RMJ. 2009, No. 4. Kornienko E.A., Saburova A.V. Experience with the use of the probiotic Acipol in the complex therapy of gastroduodenitis with bacterial overgrowth syndrome in the small intestine. Children's infections. 2021.-N 3.-P.46-50.

Perlamutrov Yu.N., Olkhovskaya K.B., Ivashkina N.Yu., Shuster A.M., Martyanov V.A. The influence of probiotics on the functional state of the epidermal barrier of facial skin // Bulletin of Dermatology and Venereology. - 2008. - No. 4. - P. 80-83.

4. The drug Atsipol, capsules LS-001915 has been registered in the Russian Federation since 2006, according to the State Register of Medicines of the Russian Federation. Consumer loyalty has been confirmed according to data from Mediaskop JSC, January-June 2019

How to take Acipol for children

Children from 3 months to 3 years are prescribed 1 tablet per day. The contents of the capsule must be dissolved in water or milk. Some parents mix the powder with food. You can take the medicine again after 48 hours.

A child from 3 years of age is prescribed 3-4 capsules per day, preferably 30 minutes before meals. The medicine has many positive reviews for constipation in children. The composition of the drug is completely safe, has no toxic effect, and is perfectly absorbed by the body.

Pharmacological properties of the drug Acipol

The drug is a mixture of a microbial mass of living antagonistically active acidophilic lactobacilli, lyophilized in a culture medium and heat-inactivated kefir grains containing a water-soluble polysaccharide. The contents of the capsule are dry biomass from light cream to cream color with a sour milk smell. Immunobiological and biological properties. The therapeutic effect of Acipol is determined by the live acidophilic lactobacilli present in it and the polysaccharide of kefir mushrooms. According to the mechanism of action, Acipol is a multifactorial drug with antagonistic activity against opportunistic microorganisms, which has a corrective effect on the intestinal microflora, increasing the overall reactivity of the body.

Indications for use of the drug Acipol

Dysbacteriosis and conditions leading to its development:

  • acute intestinal infections (dysentery, salmonellosis, rotavirus gastroenteritis, etc.);
  • chronic colitis, enterocolitis of infectious and non-infectious origin;
  • long-term antibacterial therapy.

Dysbacteriosis and insufficient weight gain caused by:

  • active antibiotic therapy for purulent-septic diseases in infants;
  • chronic, protracted recurrent diseases of the respiratory system (bronchitis, pneumonia, including pneumocystis);
  • atonic dermatitis and other allergic manifestations.

Prevention of dysbacteriosis:

  • increasing the overall resistance of the body.

Special instructions for the use of the drug Acipol

The drug cannot be used:

  • with a violation of the integrity of the packaging (cracked can);
  • unmarked or unclearly marked;
  • with altered physical properties (the integrity or shape of the capsule is damaged);
  • in the presence of foreign inclusions;
  • due to the expiration date of the drug.

Use during pregnancy and lactation: not studied. Impact on the ability to drive vehicles: no effect.

Use of the drug Acipol

Capsules are taken orally during meals without chewing, washed down with boiled water. The daily dose and duration of therapy for the patient is determined by the doctor depending on his age, the severity and duration of the disease, and the severity of dysbacteriosis. Children aged 3 months–3 years - 1 capsule 2–3 times a day, after opening the capsule shell and dissolving its contents in milk or boiled water. Children over 3 years of age and adults - 1 capsule 3-4 times a day, without opening the capsule or chewing. For acute intestinal infections, the drug is prescribed for 5–8 days. A longer course is prescribed for the treatment of children with delayed weight gain due to the chronic course of the disease, which is accompanied by dysbiosis. For the purpose of prevention, Acipol is prescribed 1 capsule 1 time per day for 10–15 days.

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