Vitamin B12 is an important substance involved in many processes in the human body. Its deficiency can provoke the development of dangerous pathologies. To compensate for the deficiency, you can buy vitamin B12 in ampoules for syringe filling. Its other name is cyanocobalamin. The solution is a clear liquid of a light pink or bright red hue. It is intended for injections and infusions.
pharmachologic effect
Cyanocobalamin is a biologically active drug that has hematopoietic, erythropotic, metabolic and antianemic effects. Accelerates tissue healing processes, normalizes the functioning of the central nervous system and the hematopoietic system, improves processes in the liver, enhances the activity of thromboplasts and prothrombin , activates the blood clotting process, reduces the amount of cholesterol in the blood.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Activates the metabolism of proteins, fats and carbohydrates . Forms an energy reserve in the body and actively participates in the process of transmitting nerve impulses. It is part of phosphocreatine and promotes the accumulation of hemoglobin in red blood cells . Stimulates bone marrow (normoblastic erythropoiesis). This drug normalizes liver function , has a positive effect on the blood coagulation system, and in high doses increases prothrombin .
Pharmacokinetics
The drug is absorbed primarily in the small (less in the large) intestine, then transported into the cell through the receptor system. In the blood it combines with transcobalamins I and II, and then is transported to tissues, where it is metabolized. In the body, this vitamin is deposited in the liver. It is excreted from the body by the renal excretory system.
The need for vitamin B12
If there is a deficiency of the substance in the body, there is a risk of developing a number of dangerous pathologies. This is due to the participation of vitamin B12 in many important processes. In particular, with its shortage, resistance to pathogenic microorganisms decreases. Deficiency of the substance negatively affects the general condition. A person quickly gets tired with minimal loads and cannot work at full capacity.
Cyanocobalamin is involved in the synthesis of many important amino acids. The substance improves blood clotting and reduces cholesterol levels. With enough of it, stress resistance improves. It is recommended to additionally take vitamin B 12 in ampoules to detoxify the body during alcoholism and stabilize liver function.
Cyanocobalamin is also prescribed to athletes. The substance protects the cardiovascular system during intense training. Vitamin B12 is used in the complex treatment of cerebral palsy in children and many other diseases.
Indications for use of the drug
- iron deficiency anemia of various origins;
- folate deficiency and vitamin deficiency anemia ;
- cirrhosis of the liver;
- dystrophy in young children;
- motor neuron disease;
- lumbosacral radiculitis ;
- cerebral palsy in children;
- lesions of the trigeminal nerve;
- multiple sclerosis ;
- polyneuropathy;
- chronic hepatitis ;
- Down syndrome;
- neuralgia, neuritis;
- skin diseases ( psoriasis , eczema ).
Indications for use
Understanding cyanocobalamin what it is, it is used in the complex treatment of various diseases in order to enhance the effects of basic drugs. This allows you to overcome dangerous diseases in the shortest possible time. As a monotherapy, the drug is usually prescribed to prevent anemia.
Vitamin B12 injections are indicated for complex therapy of various liver diseases. Thanks to them, it is possible to achieve good results in the treatment of chronic hepatitis, cirrhosis, etc. Injections can improve the condition of patients with Down syndrome. The drug is always included in the complex treatment of diseases of the nervous system and skin diseases.
Vitamin b12 in ampoules is often taken for preventive purposes. It is important when prescribed in high doses
- Biguanides for diabetes mellitus.
- Para-aminosalicylic acid for tuberculosis.
Vitamin B12 in ampoules is prescribed to prevent the occurrence of its deficiency in pathologies of the stomach and intestines, when the absorption of cyanocobalamin is impaired. Most often the need for this arises in the following cases:
- After resection of part of the stomach or small intestine.
- With the development of Crohn's disease, in which lesions appear on the walls of the intestine.
- For malignant neoplasms of the pancreas and intestines.
- With radiation sickness.
Vitamin B12 in ampoules, the price of which is available in a pharmacy, should be taken for vitamin deficiency. It will help strengthen the body's defenses against frequent colds. Since a deficiency of the substance in the body affects the condition of hair, nails and teeth, cyanocobalamin is prescribed for cosmetic purposes.
Instructions for use of Cyanocobalamin (Method and dosage)
The drug is administered intramuscularly, intravenously, subcutaneously and intralumbarally . Therapy with Cyanocobalamin is accompanied by regular monitoring of coagulation parameters and the overall blood picture. The dosage of the drug depends on the specific disease:
- for aplastic anemia, 100 mcg is administered every other day until hematological and clinical improvement is obtained;
- for iron deficiency and posthemorrhagic anemia - 30-100 mcg three times a week;
- anemia in children - 40 mcg per day for 15 days;
- neurological traumatic diseases and diseases of the nervous system - in increasing doses from 250 to 500 mcg, duration of treatment - up to 2 weeks; if the patient's condition improves - 100 mcg per day;
- damage to peripheral nerves caused by trauma - 200–400 mcg every other day for one and a half months;
- Down's disease , cerebral palsy and dystrophies in children - 15–30 mcg per day;
- diabetic neuropathy , radiation sickness - 60-100 mcg for a whole month.
- hepatitis and cirrhosis of the liver - 100 mcg per day for 30 days;
- funicular myelosis , multiple sclerosis - 15–30 mcg of solution is administered, gradually increasing the dose from 200 to 500 mcg.
The role of vitamin B12 in the body
Cyanocobalamin (vitamin B12)
was first opened in 1948. Scientists isolated a new substance from raw liver and prescribed it to treat pernicious anemia.
Over the past 70 years, cyanocobalamin has been well studied by scientists and doctors, as a result of which it was possible to establish its effect on the body:
- blocking stress hormones;
- improvement of blood clotting;
- amino acid synthesis;
- reducing the amount of cholesterol in the blood;
- detoxification of the body during alcoholism;
- improving liver function.
Cyanocobalamin helps athletes withstand heavy loads, accelerates weight loss and prevents the development of cardiovascular diseases.
It plays a special role in the functioning of the central nervous system. The vitamin complements the main therapy for cerebral palsy in children, Down's disease, intercostal neuralgia, etc.
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Interaction
Cyanocobalamin is a vitamin that is incompatible with thiamine bromide, riboflavin and pyridoxine (in one syringe). When prescribed simultaneously with antibiotics ( kanamycin, polymyxins, neomycin and tetracyclines ), the absorption of this medicine becomes difficult. Do not take together with drugs that affect blood clotting. Therefore, if you have been prescribed Cyanocobalamin, the instructions for use should be carefully studied.
Dosage of vitamin B12 in ampoules
Vitamin B12 dosage
is determined individually and depends on the patient’s age. The maximum daily dose is:
- children – 400 mcg;
- adults – 1000 mcg.
The dosage is increased gradually, you need to start with a small portion of the drug. This is necessary to avoid allergic reactions.
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Analogs
Cyanocobalamin-Darnitsa, Cyanocobalamin - Vial, Cyanocobalamin Bufus, Medivitan.
Combination preparations containing vitamin B12
There are a number of combination drugs on the market - Cyanocobalamin tablets in combination with folic acid (Russia), Nowfoods B12, Solgar Vitamin B12 (USA), Neurobion (Germany), Neurovitan (Italy). As a rule, the release form is tablets.
Reviews of Cyanocobalamin
Reviews about the drug are mostly positive. Patients note that after a course of treatment, hemoglobin increases, well-being is normalized and sleep improves, depression goes away, pain from neuralgia and inflammation of the trigeminal nerve decreases.
According to patient reviews, Cyanocobalamin in ampoules is an effective hair product. Many women are interested in how to use Cyanocobalamin for hair? Like all B vitamins, it has a positive effect on hair. Even regular (once a week) injections of the drug help strengthen hair roots and reduce hair loss. The drug is often used as a component of hair masks or in its pure form for rubbing into the hair roots.
Cyanocobalamin price, where to buy
You can buy the drug in all pharmacies. The price of Cyanocobalamin in Moscow pharmacies varies from 14.5 to 25.0 rubles per pack.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Blagomin Vitamin B12 (cyanocobalamin) capsules 9 mcg 0.2 g 90 pcs. VIS LLC
214 rub. order - Cyanocobalamin (Vitamin B12) solution for in. 0.5 mg/ml 1 ml 10 pcs. JSC Dalkhimfarm
48 RUR order
Pharmacy Dialogue
- Vitamin B12 (cyanocobalamin) (amp. 500 µg/1 ml No. 10) DHF JSC
38 rub. order
- Vitamin B12 (cyanocobalamin) (amp. 500 µg/1 ml No. 10) Yerevan chemical plant
36 RUR order
- Blagomin Vitamin B12 (cyanocobalamin) (caps. 200 mg No. 90) VIS LLC
RUB 245 order
- Vitamin B12 (cyanocobalamin) (amp. 500 µg/1 ml No. 10) BZMP
46 RUR order
- Cyanocobalamin (Vitamin B12) (amp. 500 µg/1 ml No. 10) BZMP OJSC
48 RUR order
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Pharmacy24
- Cyanocobalamin-Darnitsa 0.02% 1 ml No. 10 solution PrAT" Pharmaceutical company "Darnitsa", Ukraine
14 UAH. order - Cyanocobalamin 0.05% 1 ml No. 10 injection solution PAT "Galichfarm", Ukraine
12 UAH order
- Cyanocobalamin-Darnitsa 0.05% 1 ml No. 10 solution for injection PrAT" Pharmaceutical company "Darnitsa", Ukraine
17 UAH order
PaniPharmacy
- Cyanocobalamin solution for injection 0.05% ampoule 1 ml No. 10 Ukraine, Darnitsa ChAO
18 UAH order
- Cyanocobalamin solution for injection 0.02% ampoule 1 ml No. 10 Ukraine, Darnitsa ChAO
16 UAH order
- Cyanocobalamin solution for injection 0.05% ampoule 1 ml No. 10 Ukraine, Galichfarm JSC
14 UAH order
- Cyanocobalamin solution for injection 0.05% ampoule 1 ml No. 10 Ukraine, Lekhim-Kharkov JSC
16 UAH order
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