Nurofen Express: instructions for use, price and composition

Release form

The medicine is available in the form of coated tablets, they are packaged in blister packs, which can contain 6, 10, 12, 14 or 24 tablets.

Also available in capsules with a hard gelatin shell. The red translucent capsules have the inscription “NUROFEN” in white, inside the capsules there is a pink or translucent liquid.

Nurofen Express Neo is produced in round, white tablets. On one side of the tablet there is a black overprint “N”.

Indications for use

Nurofen Express is prescribed to patients in the following cases:

for degenerative inflammatory diseases of the musculoskeletal system ( arthritis , osteochondrosis , neuralgic amyotrophy, gouty arthritis, ankylosing spondylitis (ankylosing spondylitis));
for pain syndromes of different origins: (pain that occurs in patients with arthralgia, myalgia, arthritis, ossalgia, radiculitis, neuralgia , bursitis , as well as migraine , headache , toothache , etc.);
pain due to cancer;
pain in women suffering from menstrual syndrome;
pain syndrome after injuries and operations, in which an inflammatory process is noted;
inflammatory processes in the pelvis;
childbirth (as a tocolytic and analgesic drug);
fever due to colds and infectious diseases.

What is Nurofen syrup and tablets for?

The action of Nerofen is explained by the presence of ibuprofen in the composition, which, by acting on the thermostat in the brain, relieves fever and returns the temperature to normal values.

In addition, ibuprofen inhibits the synthesis of prostaglandins, which are mediators of pain. Which explains its analgesic effect. This is why Nurofen is indicated for:

high body temperature;
toothache;
headache;
muscle pain;
for adverse reactions after DTP.

Contraindications

Nurofen Express should not be used for the following body conditions and diseases:

hypersensitivity to the components of the drug;
erosions and ulcers of the digestive tract;
a combination of bronchial asthma (complete or incomplete), recurrent nasal and paranasal sinus polyposis with intolerance to ASA or other NSAIDs;
disturbances in the process of blood ;
bleeding from the gastrointestinal tract in active form;
severe renal failure
liver diseases that progress, active liver diseases;
period after bypass surgery;
hyperkalemia confirmed;
intestinal inflammation;
third trimester of pregnancy ;
child's age up to 12 years.

Which is safer Nurofen or paracetamol

Ibuprofen, which is part of the drug, is contraindicated for people with chronic bronchial diseases, in particular asthma. In addition, Nurofen should not be taken by patients with intolerance to the active substance, pregnant women, patients with heart failure, diagnosed liver failure and gastrointestinal bleeding.

Contraindications to taking paracetamol are the neonatal period, individual intolerance to the drug, and gastric ulcers, including erosion and inflammation of the gastrointestinal mucosa.

Side effects

During treatment with this drug, the following negative effects may develop:

digestive system : manifestations of NSAID gastropathy, ulcers of the gastrointestinal mucosa, dryness, pain and irritation in the oral cavity, pancreatitis , stomatitis , constipation , hepatitis;
respiratory system : bronchospasm, development of shortness of breath ;
sense organs : hearing impairment, ringing in the ears, blurred vision, reversible toxic optic neuritis , irritation and dryness in the eyes, swelling of the eyelids and conjunctiva;
heart and blood vessels : tachycardia , worsening condition in heart failure, increased blood pressure ;
nervous system : insomnia , anxiety, manifestations of irritability, dizziness , headache , depression , state of psychomotor agitation, hallucinations ;
urinary system : allergic nephritis, acute manifestations of renal failure, edema associated with nephrotic syndrome, cystitis , polyuria;
manifestations of allergies : rash, itching of the skin , anaphylactoid reactions, swelling, allergic rhinitis , eosinophilia, etc.;
hematopoiesis : thrombocytopenia, development of thrombocytopenic purpura, anemia, leukopenia, agranulocytosis;
other manifestations : heavy sweating .

It should be borne in mind that the likelihood of side effects increases if Nurofen Express is used for a long time in high doses.

Nurofen Express, instructions for use (Method and dosage)

The proposed instructions for use of Nurofen Express stipulate that patients take this medicine orally, after meals. Patients who suffer from psoriatic arthritis, osteoarthritis, and ankylosing spondylitis should take 400-600 mg of medication 3-4 times per day. Patients with rheumatoid arthritis are prescribed 800 mg three times a day.

Patients who have suffered soft tissue injuries , as well as sprains , should take 1.6-2.4 g of the drug per day, this dose is divided into several doses.

Patients with algodismenorrhea are prescribed 400 mg three or four times a day if moderate pain is noted.

Children over 12 years of age are prescribed an initial dose of Nurofen Express 150-300 mg three times a day, with a maximum dose of 1 g. Then 100 mg three times a day is prescribed. Patients with juvenile rheumatoid arthritis are prescribed a dose of 30-40 mg per 1 kg of body weight per day, the dose is divided into several doses.

In order to lower body temperature to 39.2 degrees or more, the drug is prescribed at a dose of 10 mg per 1 kg of body weight per day. If the body temperature does not exceed 39.2 degrees, the dose of the medicine is 5 mg per 1 kg of weight per day.

After how many hours can Nurofen be given?

Due to the fact that the drug is quickly and almost completely absorbed from the gastrointestinal tract, its maximum concentration in human plasma is reached after 30 minutes. This suggests that after taking the drug on an empty stomach, the patient’s temperature should begin to decrease within 40 minutes. When taking a single dose of the drug after a meal, the antipyretic effect should appear after an hour.

If the temperature has not started to decrease after an hour, you can give another antipyretic drug. In this case, it is better to give preference to paracetamol. Nurofen can be taken again no earlier than 4 hours after the first use.

The same dosage regimen also applies in the opposite direction, when the question arises of how long after paracetamol can be taken Nurofen. If taking paracetamol after an hour does not work, you can switch to ibuprofen.

Overdose

When taking too large doses of Nurofen Express, the patient may experience drowsiness , lethargy, gastrointestinal dysfunction, headache, depression, acute manifestations of liver and kidney failure, metabolic acidosis, bleeding, tachycardia , bradycardia, etc.

If you take an excessive dose of Nurofen Express, you should immediately rinse your stomach, then drink activated carbon , perform forced diuresis and ensure alkaline drinking. If seizures occur, the patient should be given anticonvulsant medications.

How many times can Nurofen be given to a baby?

The effect of the drug begins an hour after the first dose. The decrease in temperature can continue for up to half an hour until the values drop to normal levels. The antipyretic effect can last up to 8 hours. However, with severe inflammatory processes, the fever may return after 4-5 hours. An infant can be re-given a single dose of the drug both in the form of suppositories and in the form of syrup after 4 hours if the temperature begins to rise again. A baby can receive up to 5 permissible single doses per day.

Interaction

There is an interaction with Nurofen Express when taking the following drugs simultaneously:

when taking inducers of microsomal oxidation, there is an increase in the production of hydroxylated active metabolites , and, as a result, the likelihood of severe hepatotoxic reactions increases;
when taking microsomal oxidation inhibitors, the likelihood of hepatotoxicity decreases;
when taking antihypertensive drugs, their effect decreases, and the diuretic and natriuretic activity of hydrochlorothiazide and furosemide ;
when taking uricosuric drugs, their effectiveness decreases;
when treated with indirect anticoagulants , fibrinolytics , antiplatelet agents , their effect increases, as a result, there is an increase in the risk of developing hemorrhagic complications;
when taking estrogens , colchicine , MCS and GCS , ethanol an ulcerogenic effect is noted;
when treated with oral hypoglycemic drugs and insulin , the effectiveness of these drugs increases;
when taking cholestyramine and antacids , the absorption of ibuprofen decreases;
when taking lithium , Digoxin , Methotrexate the concentration of these drugs increases;
when taking caffeine, the analgesic effect increases;
when taking ASA , the antiplatelet and anti-inflammatory effect of such drugs is reduced;
when treated with anticoagulants and thrombolytic drugs, the risk of bleeding increases;
when treated with Cefoperazone , Cefamandole , Valproic acid , Plicamycin , Cefotetan , the frequency of hypoprothrombinemia increases;
when treated with myelotoxic drugs, manifestations of hematotoxicity increase;
when taking gold preparations and Cyclosporine, the effect of ibuprofen on the process of Pg synthesis in the kidneys increases, and as a result, nephrotoxicity increases;
when taking Cyclosporine, its plasma concentration increases and the risk of hepatotoxicity increases;
When taking medications that block tubular secretion , the plasma concentration of ibuprofen increases.

special instructions

It is necessary to carefully monitor peripheral blood counts, as well as the condition of the liver and kidneys during treatment with the drug.

If the patient has signs of gastropathy, it is necessary to conduct a series of studies prescribed by the doctor.

If it is necessary to determine 17-ketosteroids, Nurofen Express should be discontinued 48 hours before the upcoming study.

While taking the medication, you should not drive or engage in other activities that require quick reactions.

To reduce the risk of developing negative manifestations in the functions of the digestive system, you need to use a minimum dose of medication for the shortest possible period of time.

Nurofen's analogs

Level 4 ATC code matches:
Artrum

Brustan

Ketonal Duo

Nurofen Plus

Nurofen Forte

Nurofen Express Lady

Nurofen for children

Nurofen

Ibuprom

Ibuprofen

Advil

MIG 400

Has

Ketoprofen

Vimovo

Naproxen

Flexen

Nalgesin

Flamax

Novigan

Analogs of Nurofen Express are medications that contain ibuprofen as an active ingredient. These are the drugs Nurofen , Nurofen Forte , Ibuprofen , Ibufen , etc. Only a doctor should decide on the advisability of taking any of the drugs.

If Nurofen does not bring down the temperature: what to do

When the thermometer rises above 39˚C, absorption of substances from the stomach may stop. This means that taking medications orally may not have an effect. This happens especially often when the patient washes down the tablet or syrup with cold water. Once in the stomach, cold liquid forces the vessels of the gastric walls to contract, as a result of which they cannot fully pass substances through their walls.

In this case, doctors recommend giving preference to rectal suppositories at high temperatures exceeding 39˚C. The suppository, once in the rectum, quickly dissolves, and ibuprofen immediately enters the bloodstream through the intestinal walls. After 30-40 minutes, the patient’s temperature begins to decrease.

Nurofen Express price, where to buy

The price of Nurofen Express is on average 160 rubles per pack of 12 pieces.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine

ZdravCity

Nurofen Express Forte capsules 400 mg 10 pcs. Patheon Softgels B.V.
RUB 199 order
Nurofen Express capsules 200 mg 8 pcs. Patheon Softgels B.V./Reckitt Benckiser Healthcare International Ltd.
RUB 133 order
Nurofen Express Forte capsules 400 mg 20 pcs. Patheon Softgels B.V.
RUB 353 order
Nurofen Express capsules 200 mg 16 pcs. Patheon Softgels B.V./Reckitt Benckiser Healthcare International Ltd.
RUB 259 order
Nurofen Express capsules 200 mg 24 pcs. Patheon Softgels B.V./ Reckitt Benckiser Healthcare International Ltd.
RUR 387 order

Pharmacy Dialogue

Nurofen Express forte capsules 400 mg No. 20 Reckitt Benckiser
RUB 377 order
Nurofen Express (caps. 200 mg No. 24) Reckitt Benckiser
RUR 398 order
Nurofen Express capsules 200 mg No. 16Reckitt Benckiser
RUB 264 order
Nurofen Express 5% gel tube 50gReckitt Benckiser
146 RUR order
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Nurofen Express forte capsules 400 mg No. 10 Reckitt Benckiser
RUB 196 order

Pharmacy24

Nurofen Express 200 mg No. 24 tablets Reckitt Benckiser Healthcare International, Great Britain
120 UAH order
Nurofen Express Forte 400 mg No. 10 capsules Reckitt Benckiser Healthcare International, Great Britain
98 UAH order
Nurofen Express 200 mg No. 12 tablets Reckitt Benckiser Healthcare International, Great Britain
72 UAH order