Anuzol suppositories: instructions for use, reviews, price

A burning sensation, itching in the anal area and other unpleasant symptoms indicate the development of hemorrhoids. To treat it, as a rule, suppositories are used. Among the inexpensive but effective drugs is Anuzol. Many buyers note that the medicine gives results in the first days. At the same time, you can buy it at a price accessible to everyone.

Compound

One suppository includes active ingredients: 100 mg of xeroform , 20 mg of belladonna extract and 50 mg of zinc sulfate .
Additional ingredients: 11 mg polysorbate 80, 120 mg glycerol , 110 mg T2 emulsifier.

Solid fat is used as a base for suppositories, so that the weight of one suppository ranges from 2.09 to 2.31 grams.

Candles "Anuzol": composition, description

The drug "Anuzol" is produced in the form of rectal suppositories. Each suppository contains xeroform in an amount of 100 mg, belladonna extract 20 mg and zinc sulfate 50 mg. The additional components are: glycerin, emulsifier, solid fat and polysorbate. Each suppository weighs no more than 2.31 g. Suppositories are packaged in plastic blisters - 10 suppositories in 1 package.

You can store the drug in the refrigerator or in another cool place with a temperature of no more than 15 degrees Celsius. It is necessary to exclude the penetration of direct sunlight, and also limit the access of children. If these rules are followed, the product can be stored within the general shelf life, which is 2 years from the date of production.

Pharmacodynamics and pharmacokinetics

Anuzol suppositories, due to the effects of the active ingredients, are a complex-action drug aimed at the local treatment of hemorrhoids , anal fissures and other damage to the anorectal area .

Thanks to the dermatotropic and disinfectant properties of xeroform, the drug has a drying, antiseptic and astringent effect.

Zinc sulfate is also characterized by a drying effect in combination with a pronounced anti-inflammatory effect.

Belladonna (belladonna) affects the decrease in muscle tone of the gastrointestinal tract, which leads to increased sphincter tone , and its additional anticholinergic and antispasmodic effect helps prevent the stimulating effects of acetylcholine .

Pharmacodynamics

The product is used to treat hemorrhoids. Characterized by complex effects:

antispasmodic (prevents spasms);
antiseptic (disinfects);
drying;
anti-inflammatory;
astringent.

Thanks to this, the drug is effective for the treatment of anal fissures, itching and other unpleasant consequences. Xeroform acts as an antiseptic and has an astringent and drying effect. It helps to cope with inflammatory processes due to disinfection.

Zinc sulfate also acts as a drying agent. It also has an anti-inflammatory effect. Belladonna extract (also called belladonna) enhances sphincter tone, blocks spasms, allows muscles to relax, and also contributes to the treatment of hemorrhoids.

Contraindications

suppositories for hemorrhoids should not be used:

with hypersensitivity to any of the ingredients of the suppository;
for heart failure during periods of exacerbation;
with intestinal atony ;
with myasthenia gravis ;
with tachyarrhythmia ;
for benign hyperplasia ;
with closed-angle glaucoma ;
during periods of breastfeeding and pregnancy .

Side effects

loose stool;
dry mouth;
allergic manifestations;
burning sensation in the anus;
constipation;
dilated pupils;
feeling of heartbeat ;
paresis of accommodation;
feeling dizzy ;
headache;
drowsiness;
difficulty falling asleep and/or staying asleep.

Anuzol No. 10 suppositories

Trade name : Anuzol International nonproprietary name: No Dosage form: Rectal suppositories Composition: 1 suppository contains active substances: xeroform (bismuth tribromophenolate and bismuth oxide complex) 0.10 g, belladonna thick extract (belladonna leaf extract) 0.02 g, zinc sulfate heptahydrate 0.05 g, excipients: glycerol (distilled glycerin), purified water, distilled monoglycerides (MGD), solid fat (vitepsol (brands N 15, W 35), supposir (brands NA 15, NAS 50)). Description: Torpedo-shaped suppositories of greenish-yellow or greenish-yellow with a brownish tint or light brown color, with the smell of xeroform. A barely noticeable white coating may appear on the surface of the suppository. Pharmacotherapeutic group: Other drugs for the treatment of hemorrhoids and anal fissures for topical use. Other drugs and their combinations

Pharmacological properties: Pharmacokinetics Xeroform (bismuth tribromophenolate) is a poorly soluble compound in water, so the likelihood of its systemic exposure is extremely low. Belladonna alkaloids are absorbed in the gastrointestinal tract.

Pharmacodynamics Antihemorrhoidal combination drug. Anuzol has antispasmodic, anti-inflammatory, antiseptic, analgesic, local anti-inflammatory, astringent and drying effects. Xeroform (bismuth tribromophenolate) is an antiseptic, anti-inflammatory, astringent and drying agent. Belladonna extract – has an M-anticholinergic and antispasmodic effect, reduces muscle tone of the gastrointestinal tract (GIT). Zinc sulfate is an astringent and antiseptic. Glycerol is used to change the osmotic pressure in different tissues, reduce swelling, and increase osmoticity. Indications for use: - hemorrhoids - anal fissures. Directions for use and dosage : Rectally. 1 suppository 1-3 times a day after a cleansing enema or spontaneous bowel movement. The maximum daily dose of the drug is 7 suppositories. The duration of the course of treatment is 10-14 days. Side effects: - allergic reactions - burning in the anus - dry mouth - constipation, loose stools - palpitations - dilated pupils, transient visual disturbances (paresis of accommodation) - tinny pain, dizziness - sleep disturbance, drowsiness. In these cases, you should stop using the drug and consult a doctor. Contraindications: - hypersensitivity to the components of the drug - intestinal atony - heart failure in the stage of decompensation, tachyarrhythmia, myasthenia gravis - aperture-angle glaucoma - prostate adenoma - pregnancy and lactation. Drug interactions: Cases of interaction or incompatibility of the drug Anuzol, rectal suppositories, with other drugs have not been described. Special instructions: Children. Due to the fact that clinical studies of the drug Anuzol, rectal suppositories, have not been conducted in children, use in childhood (up to 18 years) is possible only after consultation with a doctor. Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms. During the treatment period, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require increased concentration, speed of psychomotor reactions and good vision. Overdose: Cases of overdose of Anuzol have not been reported. Overdose is possible if the method of administration is not followed (the drug is administered rectally) and if the drug is used in a daily dose of more than 7 suppositories. Symptoms: nausea, vomiting, psychomotor agitation, convulsions, urinary retention, decreased sweating, hyperthermia. Treatment: symptomatic. Release form and packaging: 5 suppositories are placed in a contour cell packaging made of polyvinyl chloride film laminated with polyethylene. 2 contour packages together with instructions for medical use in the state and Russian languages are placed in a cardboard pack. Storage conditions: Store in a place protected from light at a temperature not exceeding 25 °C. Keep out of the reach of children! Shelf life: 3 years. Do not use the drug after the expiration date. Conditions for dispensing from pharmacies: Without a prescription

Anuzol suppositories, instructions for use

Following the instructions for Anuzol, before using suppositories, you should cleanse the intestines (naturally or with an enema), after which you need to remove the suppository from the package using scissors. The suppository is administered rectally ( into the rectum ). Depending on the severity of the painful condition, it is recommended to use from one to three suppositories per day. The maximum possible number of suppositories used in 24 hours is seven.

Analogs

Level 4 ATC code matches:
Betiol

Olestesin

Proctosedyl

Ultraproct

Relief

Posterisan Forte

Posterisan

Bezornil

Procto-Glyvenol

Glivenol

Proctosan

Hepazolon

Betiol;
Glivenol;
Neo-Anuzol;
Posterisan;
Proctosan;
Relief;
Ultraproct , etc.

Reviews about Anuzole

Generally, reviews of Anuzol suppositories as a means of relieving hemorrhoids and anal fissures are positive. Patients note the rather rapid action of the drug and its high efficiency.

Among the negative assessments of this remedy, the most common are indications of an unpleasant odor, palpitations and some inhibition of reactions . Also, some patients report the return of symptoms of the disease after stopping the use of suppositories.

This suggests that if Anuzol can independently help eliminate anal fissures burning , damage to the anorectal area , irritation it cannot completely get rid of hemorrhoids This drug is used to alleviate or eliminate the symptoms of the disease and, unfortunately, cannot completely eliminate its cause.

In this regard, at the first signs of hemorrhoids, you should consult a competent specialist who will select complex therapy that is adequate for your condition or recommend other treatment methods.

Drug interactions and overdose

The drug can be taken with different drugs, but it should be borne in mind that the use of Anuzole can increase the effects of medications belonging to the following groups:

antispasmodics;
anticholinergics;
sedatives;
sleeping pills.

In case of overdose, symptoms such as:

nausea;
vomiting;
overexcitement;
convulsions;
urinary retention;
increased body temperature;
increased sweating.

Anuzol price, where to buy

If we compare the prices of suppositories for hemorrhoids in Russian pharmacies, then this medicine is the “golden mean” in terms of price-quality ratio.

Depending on the pharmacy chain, the price of Anuzol No. 10 suppositories varies between 55-70 rubles.