Emoxipin eye drops: in what cases do they help?

Release form

Emoquispin is available in the form of drops in a concentration of 1%. A 5 ml glass bottle is tightly closed with an aluminum dropper cap and sealed with a rubber stopper sealed around the edges. Packaged in a cardboard box with an image of an eye on a white background, which indicates the expiration date and composition of the medicinal product. Comes with instructions in Russian. There is a label attached to the bottle. The solution is transparent or with a slight yellowish tint, without a pronounced odor.

You can order eye drops on the website https://emoxypin.ru/

Compound

The active ingredient is methylethylpyridinol hydrochloride at a concentration of 10 mg per 1 ml of “Emokipin” eye drops. It improves microcirculation, relieves swelling and fatigue, and promotes the resorption of hemorrhages in the retina. Accelerates healing after surgery and prevents possible complications from injuries and burns of the cornea. Used as maintenance therapy for glaucoma and cataracts, including senile ones.

Additional substances:

• sodium sulfite E 221 (anhydrous);
• sodium benzoate E 211;
• potassium dihydrogen phosphate;
• disodium phosphate dihydrate;
• water for injections.

pharmachologic effect

If you figure out why Emoxipin is prescribed, then its main function is to have an angioprotective effect:

• strengthen the walls of blood vessels and capillaries to prevent their ruptures and thinning, especially due to age-related changes in structure and during regular work associated with eye strain (computer radiation, working with numbers, long-term driving without a break for sleep);
• protect from bright light that irritates the mucous membrane, blocks the access of harmful substances to the vascular network;
• neutralize the effects of free radicals;
• eliminate irritation, dryness and burning sensation, including after mechanical injuries;
• relieve pain and inflammation;
• maintain visual acuity;
• normalize blood viscosity:
• improve cellular metabolism in the organs of vision;
• prevent infectious spread in case of infection of one eye;
• protect the mucous membrane from the harmful effects of intense direct light, active radiation, and ultraviolet radiation.

Pharmacokinetics

The active substance in eye drops is methylethylpyridinol hydrochloride, which is an antioxidant and has a pronounced anti-inflammatory and general preventive effect on the visual system. Once on the mucous membrane of the eye, it quickly penetrates into the deep layers and accumulates in the tissues in high concentrations. Epoxipin drops are prescribed:

• for injuries and burns of the cornea, when the integrity of the ocular membrane is damaged;
• accompanying injuries or arbitrary (due to capillary fragility or increased fundus pressure) hemorrhages in the outer part;
• in the presence of an inflammatory process that causes discomfort and a burning sensation;
• to prepare for surgery and accelerate healing and recovery in the postoperative period;
• in case of deterioration of vision due to increased blood sugar (including due to diabetes mellitus);
• insufficient blood supply to the retina;
• irritation and dryness after or while wearing contact lenses;
• to relieve eye strain, eye muscle spasms:
• as a prevention of corneal dystrophy and age-related deformities.

Instructions for use and dosage

Each package of Emoxipin drops comes with instructions for use. It is sold without a prescription, but if you have any doubts about the tolerability of the active ingredients, or a history of allergic reactions to medications, then consult a specialist or your doctor before purchasing. Read the information insert, make sure that you are not at risk for contraindications - pregnancy, lactation, age under 18 years.

Before using the drops, you need to prepare the bottle:

1. Open the cardboard packaging. Be sure to check the expiration date, integrity of the bottle and dropper cap. If you notice traces of use or attempts to open it, refrain from therapy.
2. To get rid of the aluminum protective cover, take sharp manicure scissors, pry it by the bottom edge and pull it up, or make an incision at the top in specially marked places and pull it down - with any of the methods, the integrity will be compromised and you will be able to remove the rubber stopper without any problems. Do not use a knife for these purposes to avoid injury.
3. Take out a plastic pipette and pour boiling water over it to comply with sanitary and hygienic rules.
4. Place it tightly onto the neck of the bottle and turn it upside down so that the first drop pushes out the air lock. You can tap the bottom with your finger or shake it to speed up the process.
5. Remove the protective cap from the pipette, and without touching the eye, at a distance of 1-2 cm, press the plastic pipette in the center area so that the drop falls on the mucous membrane.
6. After use, rinse the dropper, seal the bottle tightly and refrigerate until next time.

The standard treatment regimen with Emoxipin is 2-3 times a day, 1-2 drops into each eye sac. The duration of treatment is from 3 to 30 days. Eye drops have a cumulative effect - if necessary, the course is repeated every six months. Do not stop using it after the first symptoms have passed - follow the period prescribed by your doctor.

Algorithm for proper use of the drug:

1. Take out the bottle and leave it to warm up at room temperature - it should not be cold to minimize the unpleasant feeling during instillation. An inflamed eye reacts painfully to cold.
2. Wash your hands thoroughly and prepare two cotton swabs.
3. Tilt your head back and gently pull the lower eyelid down until the conjunctiva becomes visible.
4. Place 1-2 drops and close your eyes for a few minutes for complete absorption. If a tear appears at this time, do not wipe it with your hands to limit the risk of infection - use a cotton pad or a clean handkerchief.
5. If you are a driver, then do not use the drug while driving - it does not affect the reaction speed, but in the first minutes the sharpness will disappear, your eyes may sting, and tears will appear. Wait 20 minutes from the moment of the procedure for the clarity of vision to fully return.

Contraindications and negative reactions

An absolute contraindication to the use of emoxipine solution is hypersensitivity to its components. This means that you must carefully read the composition of the spray.

Do not use the medicine for treatment under 18 years of age, during pregnancy and lactation. To minimize the risks of chronic diseases, emoxipine is prescribed with caution to elderly people. With intravenous invasions, complications may arise in the event of hemostasis disturbances during surgical operations, as well as in patients with signs of severe bleeding.

Side effects when using eye drops often include burning and itching. Swelling and hyperemia of the conjunctiva may also appear.

When administered intravenously, in addition to negative reactions at the injection site in the form of itching and burning, drowsiness and increased blood pressure may occur. In the presence of diseases of the digestive system, discomfort in the epigastric region and nausea are sometimes observed during the use of the medicine. Rare side effects include headache and discomfort in the heart area.

Side effects

The tolerability of each drug, including Emoxipin eye drops, is determined individually. In case of personal intolerance to one of the components of the drug, typical allergic reactions may occur:

• burning sensation;
• itching;
• tearfulness;
• tension of the mucous membrane;
• pain and blurred vision.

If the feeling of discomfort does not go away on its own within half an hour from the moment of instillation, then you will have to abandon eye drop therapy.

According to studies, the product is safe, without side effects and effects on the central nervous system, cardiovascular system and vestibular system.

Prescribe with caution to women during pregnancy and lactation. According to the instructions, Emoxipine is allowed from the age of 18, but in pediatrics and pediatric ophthalmology cases of use in emergency cases (hemorrhage in the retina) were allowed for children from one year of age without recorded side effects.

Contraindications, adverse reactions

The medication does not have an extensive list of prohibitions for use. Among them, only individual high susceptibility to the components of the solution. During the period of bearing a child, use with great caution is allowed. Prohibited during breastfeeding.

Side effects may include allergic manifestations, burning after instillation, itching, temporary hyperemia of the mucous membrane of the eyes, thickening of the eye tissue, lacrimation. Discomfort usually occurs on its own. If complications persist for a long time, the eyes should be rinsed with water. You need to see a doctor. In general, the drug is considered safe.

Overdose

According to the scheme indicated in the package insert, treatment with Emoxipin is carried out 2-3 times a day, 1-2 drops in each conjunctival sac. This dosage is sufficient for a therapeutic effect. If you accidentally instilled more, or missed one dose and decided to compensate with a double dose, there will be no consequences from this, but the treatment will not become faster. If you feel discomfort or a strong burning sensation, rinse your eyes with purified water or saline solution. If symptoms persist for more than a day, contact your doctor for help and advice.

How to instill Emoxipin

Drops are instilled into the conjunctival sac, one or two drops in each eye. Frequency: two to three times a day. The duration of treatment ranges from three days to one month.

If no complications arise during treatment and there is a need to use drops, therapy can be continued for six months. Or you can conduct courses two or three times a year.

To instill the drug yourself, you must:

• tilt your head back and look upward;
• turn the bottle upside down with the dropper;
• gently pull the lower eyelid down a little so that the conjunctiva is visible;
• It is necessary to keep the tip of the dropper at a distance of no closer than two to three centimeters from the surface of the eye;
• press the dropper so that one drop falls on the conjunctiva.

To allow the solution to be absorbed, you can press lightly on the inner corner of the eye with a clean finger. The procedure is then repeated for the second eye.

It is advisable to avoid activities that require visual strain; it is better to keep your eyes closed and lie down.

Interaction with other drugs

The drug Emoxipin is compatible with all medications, except eye drops. It is prohibited to use several types of funds at the same time. Otherwise, the manufacturer cannot be held responsible for the absence of side effects and therapeutic effect stated in the instructions for use.

If the ophthalmologist prescribed additional eye drops, then it is imperative to fulfill the condition - Emokispin is instilled last, maintaining an interval of at least 15 minutes.

Reviews

On the Internet you can find various reviews of Emoxipin eye drops from both doctors and patients.

Ophthalmologists note a negative property of the drug - the ability to greatly irritate the eyes during installation. I also don't like the lack of proven effectiveness. Proponents of the drug point to its good ability to resolve subconjunctival hemorrhages and improve blood microcirculation.

Patients also do not always notice positive dynamics after instillation; they do not like the strong burning sensation.

Emoxipine analogues

Despite its pronounced therapeutic effect and good reviews, the drug is not suitable for all patients. If you feel pain in the eyes, burning, itching, sharp redness of the mucous membrane after using the drug, and the painful sensation does not go away within half an hour, it means that the body is experiencing an allergic reaction to one of the components in the composition. Individual intolerance requires replacing the drops with ones with similar pharmacological properties, but with a modified active formula.

A wide range of modern pharmaceutical products offers the following analogues of eye drops with methylethylpyridinol hydrochloride in the composition:

• Vixolin 1% - available by prescription, not recommended for pregnant women or during breastfeeding. It is not a prophylaxis, it is intended directly for treatment. Not used in the pre- and post-operative period. Produced in Russia by Grotesk LLC. The average price in Moscow and the region is 350 rubles;
• Emoxy-optic - eye drops aimed at treating hemorrhage in the anterior chamber of the eye due to trauma, as well as age-related changes in the elderly. It has an antiseptic effect, extinguishes inflammation and relieves painful syndrome in case of burns and injuries of the cornea. Prescribed as a prophylaxis to maintain visual acuity for people suffering from myopia and myopathy. Price from 160 to 230 rubles in the Russian Federation;
• Emoxybel is the most budget-friendly analogue, priced from 98 rubles, depending on the chosen manufacturer. But with a larger list of indications for use, it has a number of negative side effects: increased blood pressure, can cause drowsiness or short-term agitation. Patients suffering from concomitant diseases of the cardiovascular system and central nervous system are not recommended for use. Used for complex treatment of visual organs, including corneal dystrophy and retinal detachment;
• Emsibel is a Belarusian drug from RUE “Belmedpreparaty” with good tolerability and treatment results. Strengthens blood vessels, prevents platelet aggregation and saturates the retina with oxygen. When treated with courses, it reduces the risk of developing age-related diseases - glaucoma and cataracts, thinning of the uvea, corneal dystrophy. Accelerates tissue regeneration after injuries. Contraindications: pregnancy and age under 18 years. Price - from 210 rubles in Moscow and regions of the Russian Federation;
• Taufon 4% - differs in composition from all the drugs described above. The active ingredient is taurine. Effectively affects all types of catarrh (age-related, traumatic, diabetic), improves metabolism in the eye tissues, stimulates regeneration if vision deterioration is the result of injury to the cornea. Accelerates healing of the cornea during erosion, strengthens capillaries, preventing hemorrhages. The average cost in the Russian Federation is 108 - 130 Russian rubles.

Emoxipin-Belmed solution for IV and IM administration 30 mg/ml 10 ml No. 1

Name

Emoxipin-Belmed.

Description

Transparent colorless or slightly yellowish solution.

Main active ingredient

Emoxipin.

Release form

5 ml in ampoules in blister packaging No. 5x1, No. 5x2 or in 10 ml bottles in packaging No. 1, No. 40.

pharmachologic effect

It is an inhibitor of free radical processes, an antihypoxant and an antioxidant. Reduces blood viscosity and platelet aggregation, increases the content of cyclic nucleotides (cAMP and cGMP) in platelets and brain tissue, has fibrinolytic activity, reduces the permeability of the vascular wall and the risk of hemorrhage, promotes their resorption. Dilates coronary vessels, in the acute period of myocardial infarction, limits the size of the necrosis focus, improves the contractility of the heart and the function of its conduction system. With high blood pressure (BP) it has a hypotensive effect. In acute ischemic disorders of cerebral circulation, it reduces the severity of neurological symptoms and increases tissue resistance to hypoxia and ischemia.

Pharmacokinetics

When administered intravenously at a dose of 10 mg/kg, the half-life of T1/2 is 18 minutes; total CI clearance - 0.2 l/min; apparent volume of distribution Vd - 5.2 l. The drug quickly penetrates into organs and tissues, where it is deposited and metabolized. Five metabolites of emoxypine were discovered, represented by dealkylated and conjugated products of its transformation. Metabolites of emoxipine are excreted by the kidneys. 2-ethyl-6-methyl-3-hydroxypyridine phosphate is found in significant quantities in the liver. In pathological conditions, for example, in the case of coronary occlusion, the pharmacokinetics of emoxypine changes. The rate of elimination decreases and the time spent by emoxipine in the bloodstream increases, which may be due to its return from the depot, including from the ischemic myocardium.

Indications for use

As part of combination therapy: In neurology and neurosurgery: hemorrhagic stroke in the recovery period, ischemic stroke in the internal carotid artery and in the vertebrobasilar system, transient cerebrovascular accidents, chronic cerebral circulatory failure, traumatic brain injury accompanied by brain contusions; postoperative period in patients with traumatic brain injury, operated on for epidural, subdural and intracerebral hematomas, combined with brain contusions; pre- and postoperative period in patients with arterial aneurysms and arteriovenous malformations of cerebral vessels. In cardiology: acute myocardial infarction, prevention of “reperfusion syndrome”, unstable angina.

Directions for use and doses

Doses and duration of treatment are determined individually. In neurology and neurosurgery, emoxipine is used intravenously in a daily dose of 5–10 mg/kg for 10–12 days. Before administration, emoxipine is diluted in 200 ml of isotonic sodium chloride solution. Inject at a rate of 20 - 30 drops per minute. Subsequently, they switch to intramuscular administration of 2 - 10 ml of a solution of 30 mg/ml emoxypine (60 - 300 mg) 2 - 3 times a day for 10-30 days. In cardiology, they begin with intravenous drip (20 - 40 drops per minute) administration of 20 - 30 ml of a solution of 30 mg/ml emoxypine (600 - 900 mg) in 200 ml of isotonic sodium chloride solution 1 - 3 times a day for 5 - 15 days depending on the course of the disease, followed by a transition to intramuscular administration of 2 - 10 ml of a solution of 30 mg/ml emoxipine (60-300 mg) 2 - 3 times a day for 10 - 30 days. Treatment with emoxipine, in the case of intravenous and intramuscular administration, should be carried out under the control of blood pressure and the functional state of the blood coagulation and anticoagulation systems.

Use during pregnancy and lactation

Use during pregnancy and lactation is contraindicated.

Precautionary measures

It is necessary to constantly monitor blood pressure and blood clotting during treatment. Impact on the ability to drive vehicles and other potentially dangerous mechanisms. During treatment, it is necessary to refrain from engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Interaction with other drugs

Emoxipine is pharmaceutically incompatible with other drugs, therefore mixing in the same syringe or infusion pump with other injectable drugs is not allowed.

Contraindications

Increased individual sensitivity to emoxipine, pregnancy, lactation, children under 18 years of age. With caution: in patients with impaired hemostasis, during surgery or in patients with symptoms of severe bleeding (due to the effect on platelet aggregation).

Compound

Active substance – emoxipine – 150.0 mg/300.0 mg; excipients - sodium sulfite anhydrous, disodium phosphate dihydrate, water for injection.

Overdose

In case of overdose, the severity of the side effects of the drug may increase. Symptoms: increased blood pressure, agitation or drowsiness, headache, pain in the heart, nausea, discomfort in the epigastric region. Possible bleeding disorder. Treatment: symptomatic therapy, there is no specific antidote.

Side effect

With intravenous administration, a burning sensation may occur along the vein; Increased blood pressure, agitation or drowsiness, and blood clotting disorders may occur. In rare cases, headache, pain in the heart, nausea, discomfort in the epigastric region, itching and redness of the skin are possible.

Storage conditions

Store in a place protected from light at a temperature not exceeding 25 °C. Keep out of the reach of children.

Buy Emoxipin-Belmed solution for intravenous, intramuscular administration. 30 mg/ml in 10 ml bottle in pack No. 1 in the pharmacy

Price for Emoxipin-Belmed solution for intravenous, intramuscular injection, 30 mg/ml in 10 ml bottle in pack No. 1

Instructions for use for Emoxipin-Belmed solution for intravenous, intramuscular injection, 30 mg/ml in 10 ml bottle in pack No. 1

Precautionary measures

When using Emoxipin drops, no allergic reactions or side effects were identified. In reviews of eye drops, users note the affordable price, but some complain about the lack of effect. The manufacturer warns against purchasing the medicine from hand, not from pharmacy chains or spontaneous retail outlets.

Improper storage, transportation and counterfeit goods will have a detrimental effect on the organs of vision. Also pay attention to the prices - too high or low should raise doubts about the originality of the drug.

You can buy the medicine throughout the Russian Federation and the Republic of Belarus in the public domain without prior ordering from official pharmacy chains.

Another important indicator that must be checked is the release date, expiration date, series and lot number. They must match on the cardboard packaging and glass bottle.

Do not use a drug you are not sure about.

Where can you buy Emoxipin in Moscow

Here are the best deals for buying Emoxipin eye drops.

Moscow

• online store apteka.ru - 263.00 with free delivery to 892 pharmacies in Moscow;
• online pharmacy stolichki.ru - promotional price 221.00, subject to ordering on the website. Reservations for a day are possible;
• network "Main Pharmacy" - 255.00 rubles;
• "ABC-pharmacy" - 278.00 rubles;
• 24-hour pharmacy "NEOPHARM" - 358.00.

Description and effect of the product

In the drug emoxipine, the instructions indicate this, the active ingredient is methylethylpyridinol hydrochloride. The product is produced in the form of a solution and can be packaged in ampoules or 5 ml bottles equipped with a pipette.

When used, Emoxipine has the following effects:

• Antioxidant. This helps prevent the negative effects of free radicals on cell membranes.
• Antihypoxic, which is aimed at increasing tissue resistance to hypoxia.
• Angioprotective. The product strengthens the walls of blood vessels, improves microcirculation and metabolic processes.
• Antiaggregation. Thanks to it, it is possible to reduce the risk of platelets sticking together and reduce the likelihood of blood clots.

The main effect of emoxipine eye drops is to strengthen vascular membranes and reduce the tendency to hemorrhage. When using the product, the level of intraocular fluid is normalized. Also, emoxipin eye drops, the instructions for use indicate this, help resolve minor hemorrhages inside the eye.

When using emoxipin eye drops, it is possible to:

• Stabilize and strengthen the cell membranes in the membranes of the eyes.
• Improve blood microcirculation, against the background of which the processes of oxygen saturation of tissues are activated.
• Increase eye resistance to bright sunlight and other negative factors.
• Reduce blood viscosity and the rate of blood clotting.
• Optimize oxidative processes in mucous membranes and reduce the number of free radicals.
• Block the synthesis of prostaglandins and leukotrienes, which contribute to inflammation.
• Increase energy potential at the cellular level and metabolism.

The medicine can be used for intramuscular or intravenous administration. Emoxipine injections dilate the blood vessels of the heart, so they are often prescribed in the treatment of myocardial infarction. Also, infusions and injections are indicated to increase the brain's resistance to hypoxia.

Where can you buy Emoxipin in the regions of the Russian Federation

Emoxipine is available in the regions of the Russian Federation:

• FarmLand pharmacy (Tyumen) - 213.00 Russian rubles;
• online pharmacy "April" Krasnodar - regular price 316 rubles, but if you have a club card 217.00;
• online platform "Zdravcity" - 244.00 (Arkhangelsk region);
• “Planet of Health” - 226 Russian rubles 00 kopecks. (in the Tomsk region);
• MAGNIT-pharmacy - 231 Russian rubles.

Also, the manufacturer points out that in some pharmacies and online stores there is an o in the description - in this case, you will not be able to buy the product without a doctor’s permission. The drug is produced by a domestic pharmaceutical company and is therefore available even in isolated regions. Using an online application, you can order Emoxipin to the nearest post office or have it delivered by courier to your address.

When ordering drops, do not forget to look at the description, expiration date and manufacturer. After receiving your order, immediately check the integrity of the packaging.