PIOBACTERIOPHAGE COMPLEX solution for oral, local and external use 100ml bottle

PIOBACTERIOPHAGE COMPLEX solution for oral, local and external use 100ml bottle

Pyobacteriophage is intended for local and oral use, as well as for rectal administration. Treatment of purulent-inflammatory processes is recommended through simultaneous local and oral administration of the drug Piobacteriophage. Depending on the location of the infection, Pyobacteriophage is recommended for: 1. Local application in the form of lotions, irrigations, applications and tampons, moistened solutions. In this case, use the required amount of solution based on the size of the affected area. For abscesses, the solution should be injected into the cavity after removing the pus by puncture (the volume of the solution should be slightly less than the volume of the extracted pus). 2. Injection of the solution into the pleural, articular and other limited cavities. After administering the required amount of bacteriophage, capillary drainage is left, through which repeated doses of the drug are subsequently administered. 3. Injection of the solution into the drained cavity of the bladder and renal pelvis through a cystostomy or nephrostomy. 4. Introducing the solution into the uterine or vaginal cavity, including in the form of tampons soaked in the solution. 5. Instillation, washing and rinsing, as well as the introduction of turundas moistened with a solution, in otolaryngological practice. 6. Applications to the conjunctival sac in ophthalmological practice. 7. Insertion of moistened turundas into periodontal pockets in dental practice. 8. Introductions into the rectum in the form of enemas in gastroenterological practice. The dose of the drug Piobacteriophage and the duration of the course of therapy are determined by the doctor. A single dose recommended for children under 6 months is 5 ml when administered orally or 10 ml when administered rectally. A single dose recommended for children 6-12 months is 10 ml when administered orally and 20 ml when administered rectally. A single dose recommended for children 1-3 years old is 15 ml when administered orally and 30 ml when administered rectally. A single dose recommended for children 3-8 years old is 20 ml when administered orally and 40 ml when administered rectally. A single dose recommended for children over 8 years of age and adults is 30 ml when administered orally and 50 ml when administered rectally. In the treatment of purulent-inflammatory diseases and intestinal diseases, as a rule, the appropriate single dose is prescribed three times a day. If, when using a bacteriophage locally, the wound was pre-treated with an antiseptic, it is necessary to wash the wound with a 0.9% sodium chloride solution before using the Piobacteriophage solution. For children under 6 months of age with enterocolitis and sepsis, Piobacteriophage solution is administered in the form of high enemas twice or thrice a day. If the child does not develop regurgitation and vomiting, the drug can be given orally. The average duration of therapy is from 5 to 15 days. As a prophylaxis, the drug is prescribed in a single dose twice a day for 5-7 days.

Pyobacteriophage complex

Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and through the mouth, for 7-20 days (according to clinical indications).

Depending on the nature of the source of infection, the bacteriophage is used:

1. Locally in the form of irrigation, lotions and tamponing with liquid phage in an amount of up to 200 ml, depending on the size of the affected area. For abscesses, the bacteriophage is injected into the cavity of the lesion after removing the pus using a puncture. The amount of the administered drug should be slightly less than the volume of removed pus. In case of osteomyelitis, after appropriate surgical treatment, 10-20 ml of bacteriophage is poured into the wound.

2. Introduction into cavities - pleural, articular and other limited cavities of up to 100 ml of bacteriophage, after which capillary drainage is left, through which the bacteriophage is reintroduced over several days.

3. For cystitis, pyelonephritis, urethritis, the drug is taken orally. If the cavity of the bladder or renal pelvis is drained, the bacteriophage is injected through the cystostomy or nephrostomy 1-2 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis.

4. For purulent-inflammatory gynecological diseases, the drug is administered into the cavity of the vagina and uterus in a dose of 5-10 ml once daily.

5. For purulent-inflammatory diseases of the ear, throat, nose, the drug is administered in a dose of 2-10 ml 1-3 times a day. The bacteriophage is used for rinsing, washing, instillation, and introducing moistened turundas (leaving them for 1 hour).

6. For conjunctivitis and keratoconjunctivitis, the drug is instilled 2-3 drops 4-5 times a day, for a purulent corneal ulcer - 4-5 drops, for purulent iridocyclitis, the drug is used 6-8 drops every 3 hours in combination with oral administration.

7. In the treatment of stomatitis and chronic generalized periodontitis, the drug is used in the form of rinses in the mouth 3-4 times a day in a dose of 10-20 ml, as well as by introducing turundas impregnated with pyobacteriophage into the periodontal pockets for 5-10 minutes.

8. For intestinal forms of the disease, diseases of internal organs, dysbacteriosis, the bacteriophage is used orally and in an enema. The bacteriophage is given orally 3 times a day on an empty stomach 1 hour before meals. In the form of enemas, they are prescribed once a day instead of once taken by mouth.

Recommended dosage of the drug

The use of bacteriophages does not exclude the use of other antibacterial drugs. If chemical antiseptics were used to treat wounds before using the bacteriophage, the wound should be thoroughly washed with a sterile 0.9% sodium chloride solution.

Use of bacteriophage in children (up to 6 months)

For sepsis and enterocolitis in newborns, including premature babies, the bacteriophage is used in the form of high enemas (through a gas tube or catheter) 2-3 times a day (see table). In the absence of vomiting and regurgitation, it is possible to use the drug by mouth. In this case, it is mixed with breast milk. A combination of rectal (in enemas) and oral (by mouth) use of the drug is possible. The course of treatment is 5-15 days.

In case of recurrent course of the disease, repeated courses of treatment are possible.

In order to prevent sepsis and enterocolitis during intrauterine infection or the risk of nosocomial infection in newborns, the bacteriophage is used in the form of enemas 2 times a day for 5-7 days.

In the treatment of omphalitis, pyoderma, and infected wounds, the drug is used in the form of applications twice daily (a gauze pad is moistened with a bacteriophage and applied to the umbilical wound or to the affected area of ​​the skin).

Pyobacteriophage complete liquid 100ml (Microgen)

Pyobacteriophage is intended for local and oral use, as well as for rectal administration. Treatment of purulent-inflammatory processes is recommended through simultaneous local and oral administration of the drug Piobacteriophage. Depending on the location of the infection, Pyobacteriophage is recommended for: 1. Local application in the form of lotions, irrigations, applications and tampons, moistened solutions. In this case, use the required amount of solution based on the size of the affected area. For abscesses, the solution should be injected into the cavity after removing the pus by puncture (the volume of the solution should be slightly less than the volume of the extracted pus). 2. Injection of the solution into the pleural, articular and other limited cavities. After administering the required amount of bacteriophage, capillary drainage is left, through which repeated doses of the drug are subsequently administered. 3. Injection of the solution into the drained cavity of the bladder and renal pelvis through a cystostomy or nephrostomy. 4. Introducing the solution into the uterine or vaginal cavity, including in the form of tampons soaked in the solution. 5. Instillation, washing and rinsing, as well as the introduction of turundas moistened with a solution, in otolaryngological practice. 6. Applications to the conjunctival sac in ophthalmological practice. 7. Insertion of moistened turundas into periodontal pockets in dental practice. 8. Introductions into the rectum in the form of enemas in gastroenterological practice. The dose of the drug Piobacteriophage and the duration of the course of therapy are determined by the doctor. A single dose recommended for children under 6 months is 5 ml when administered orally or 10 ml when administered rectally. A single dose recommended for children 6-12 months is 10 ml when administered orally and 20 ml when administered rectally. A single dose recommended for children 1-3 years old is 15 ml when administered orally and 30 ml when administered rectally. A single dose recommended for children 3-8 years old is 20 ml when administered orally and 40 ml when administered rectally. A single dose recommended for children over 8 years of age and adults is 30 ml when administered orally and 50 ml when administered rectally. In the treatment of purulent-inflammatory diseases and intestinal diseases, as a rule, the appropriate single dose is prescribed three times a day. If, when using a bacteriophage locally, the wound was pre-treated with an antiseptic, it is necessary to wash the wound with a 0.9% sodium chloride solution before using the Piobacteriophage solution. For children under 6 months of age with enterocolitis and sepsis, Piobacteriophage solution is administered in the form of high enemas twice or thrice a day. If the child does not develop regurgitation and vomiting, the drug can be given orally. The average duration of therapy is from 5 to 15 days. As a prophylaxis, the drug is prescribed in a single dose twice a day for 5-7 days.

Pyobacteriophage watered.purification liquid. 20ml fl 4 pcs

The drug is used for oral administration (orally), in the form of enemas, applications, irrigations, injection into wound cavities, vagina, uterus, nose, sinuses, as well as into drained cavities: abscesses, abdominal, pleural, bladder, renal pelvis. The drug is taken orally on an empty stomach 0.5-1 hour before meals.

Recommended dosages of the drug for 1 dose, depending on age: Age 0 - 6 months: orally - 5 ml, in enema - 5-10 ml; Age 6 - 12 months: orally - 10 ml, in enema - 10-20 ml; Age from 1 year to 3 years: orally - 15 ml, in enema - 20-30 ml; Age from 3 to 8 years: orally - 20 ml, in enema - 30-40 ml; Ages from 8 years and older: orally - 30 ml, in enema - 50-60 ml.

Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and by taking the drug orally.

If the cavity of a purulent lesion is treated with chemical antiseptics, before using the bacteriophage, it must be washed with a sterile 0.9% sodium chloride solution.

When treating tonsillitis, pharyngitis, laryngitis, the drug is used to rinse the mouth and throat 3 times a day, 10-20 ml, the course of treatment is 7-10 days.

When treating bronchitis and pneumonia, the drug is taken orally 3 times a day, 10-20 ml, and is also used in the form of aerosols and inhalations (without heating and the use of ultrasound), the course of treatment is 15-20 days.

In the treatment of otitis, the drug is used for washing and introducing 2-5 ml into the middle ear cavity 1-3 times a day. The course of treatment is 7-15 days.

When treating inflammation of the sinuses, the drug is used to rinse the nasal cavity, nasopharynx and sinuses in a dose of 5-10 ml and inject 2-3 ml into the sinuses. The procedure is repeated once daily for 7-10 days. In addition, the drug is administered into the nasal cavity in the form of turundas moistened with bacteriophage, in turn into each nasal passage and left for 0.5-1 hour. The procedure is repeated 3 times a day, the course of treatment is 7-15 days.

In the treatment of stomatitis and chronic periodontitis, the drug is used in the form of rinses in the mouth 3-4 times a day in a dose of 10-20 ml, as well as by introducing turundas impregnated with bacteriophage into the periodontal pockets for 5-10 minutes, the course of treatment is 7-10 days.

For conjunctivitis and keratoconjunctivitis, the drug is used 2-3 drops 4-5 times a day, the course of treatment is 5-7 days; for a purulent corneal ulcer - 4-5 drops per day for 7-10 days, for purulent iridocyclitis - 6-8 drops every 3 hours in combination with oral administration in therapeutic dosages for 7-10 days.

In case of an abscess, after opening and removing the purulent contents, the drug is administered in an amount less than the volume of removed pus once daily, the course of treatment is 7-10 days.

For peritonitis and pleurisy, the drug is administered into the drained cavities - abdominal and pleural through drainage tubes - 20-70 ml once daily, the course of treatment is 10-15 days.

For osteomyelitis, the drug is administered into the wound cavity through turundas and drainages in the amount of 10-30 ml once daily, the course of treatment is 15-20 days.

In the treatment of mastitis, suppuration of wounds and burns, the drug is used in the form of irrigation, applications, dressings, injection into drainage in a dose of 5-50 ml depending on the lesion at least 1 time per day, the course of treatment is 10-15 days.

In the treatment of purulent-inflammatory gynecological diseases (suppuration of wounds, endometritis, vulvitis, bartholinitis, colpitis, salpingoophoritis), the drug is used for irrigation, applications, administered into wound cavities, vagina, uterus, 5-20 ml once a day for 7-10 days.

For cystitis, pyelonephritis, urethritis, the drug is taken orally in a therapeutic dose 3 times a day 1 hour before meals for 10-20 days. If the cavity of the bladder or renal pelvis is drained, the drug is administered through a cystostomy or nephrostomy 1-3 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis, the course of treatment is 7-15 days.

For gastroenterocolitis, pancreatitis, cholecystitis, as well as intestinal dysbiosis, the bacteriophage is taken orally in age-specific dosages 3 times a day 1 hour before meals for 7-15 days (according to clinical indications). For indomitable vomiting, the drug is used in the form of high enemas 2-3 times a day, 20-40 ml. In case of intestinal dysbiosis, the drug can be used with normal flora preparations.

To prevent hospital-acquired surgical infections, the drug is used to treat postoperative and newly infected wounds in a dose of 5 - 50 ml, depending on the lesion, once daily for 5-7 days.

USE of the drug in children under 1 year of age (including premature infants).

For gastroenterocolitis, pneumonia and sepsis of newborns, the drug is used by mouth 2-3 times a day, 3-5 ml, 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a gas outlet tube or catheter) once daily in a dose of 5-10 ml. A combination of rectal (in the form of high enemas) and oral administration of the drug is possible. The course of treatment is 7-15 days (according to clinical indications). In case of recurrent course of the disease, repeated courses of treatment are possible.

In the treatment of omphalitis, pyoderma, and infected wounds, the bacteriophage is used in the form of applications of 5-10 ml 2-3 times a day (a gauze pad is moistened with the bacteriophage and applied to the umbilical wound or affected area of ​​skin) for 7-15 days.

In order to prevent the occurrence of nosocomial infection in newborns, the bacteriophage is used according to epidemic indications orally 3-5 ml 3 times a day 30 minutes before feeding during the entire period of hospital stay.