Hexicon 05% 20g gel for local and external use


How to use the solution

The solution can be used externally and locally in the form of rinses and irrigations. Apply about 5-10 ml to the affected area. Repeat 2 times a day.

In order to prevent sexually transmitted infections, you should use the solution no later than 2 hours from the moment of unprotected intercourse.

A special nozzle in the package allows you to inject the solution into the urethra (up to 3 ml) or into the vagina (up to 10 ml). You need to hold the nozzle for a couple of minutes. The solution must be wiped over the inside of the thigh and genitals.

Hexicon 0.5% 20g gel for local and external use

pharmachologic effect

Antiseptic for local use in gynecology.

Composition and release form Hexicon 0.5% 20g gel for local and external use

Vaginal suppositories - 1 sup.:

  • Active ingredients: chlorhexidine digluconate in the form of a solution (20% concentration) - 16 mg;
  • Excipients: base for suppositories - a sufficient amount to obtain a suppository weighing 3.1 g - macrogol 1500 (polyethylene oxide 1500) 92-98%, macrogol 400 (polyethylene oxide 400) 8-2%.

1 or 5 pcs. — contour cell packaging (1, 2) — cardboard packs.

Description of the dosage form

Vaginal suppositories are white or white with a yellowish tint, torpedo-shaped, marbling of the surface is allowed.

Characteristic

Antiseptic drug for local use.

Directions for use and doses

To prevent sexually transmitted infections, 1 suppository is prescribed once. The drug should be used no later than 2 hours after sexual intercourse.

For treatment, 1 suppository is prescribed 2 times a day for 7-10 days.

Pharmacodynamics

Antiseptic drug for local use.

Active against gram-positive and gram-negative bacteria: Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis; protozoa: Trichomonas vaginalis; viruses: Herpes simplex types 1 and 2.

Hexicon® does not interfere with the functional activity of lactobacilli.

Remains active (albeit somewhat reduced) in the presence of blood and pus.

Pharmacokinetics

When administered intravaginally, it is practically not absorbed and has no systemic effect.

Indications for use Hexicon 0.5% 20g gel for local and external use

  • prevention of sexually transmitted infections (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis, genital herpes);
  • prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth and abortion, before and after installation of an intrauterine device, before and after diathermocoagulation of the cervix, before intrauterine examinations);
  • treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonas).

Contraindications

Hypersensitivity to the components of the drug.

Application of Hexicon 0.5% 20g gel for local and external use during pregnancy and breastfeeding

The drug is not contraindicated for use during pregnancy and lactation (breastfeeding).

In childhood, it is recommended to use the drug Hexicon® D.

special instructions

In childhood, it is recommended to use the drug Hexicon® D.

Overdose

Currently, no cases of overdose of Hexicon® have been reported.

Side effects Hexicon 0.5% 20g gel for local and external use

Possible: allergic reactions, itching, which disappear after discontinuation of the drug.

Drug interactions

Hexicon® is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. Toilet of the external genitalia does not affect the effectiveness and tolerability of Hexicon® vaginal suppositories, because the drug is used intravaginally.

Where to put Hexicon candles

The suppository is inserted into the vagina as deeply as possible. To prevent the contents from leaking out, it is better to take a lying position and spread your legs at the knees. If the candle is not inserted deeply enough, then when the girl gets up, it may fall out without completely dissolving.

Suppositories work in exactly the same way as vaginal baths. Hexicon must be administered several times a day, as a result of which the amount of discharge increases. That is why during therapy it is worth wearing a new panty liner as often as possible.

Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

pharmachologic effect

Chlorhexidine is an antiseptic drug for local intravaginal use, active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex 2 type. Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria, bacterial spores, and fungi are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of blood and pus.

Composition and release form Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

One tablet contains:

active ingredient - chlorhexidine bigluconate - 16.0 mg (in the form of chlorhexidine bigluconate solution 20% - 85.2 mg);

excipients: microcrystalline cellulose, pregelatinized corn starch, povidone K 17, stearic acid, lactose monohydrate. Vaginal tablets 16 mg. 5 or 10 tablets in a blister pack made of polyvinyl chloride film and printed varnished aluminum foil. 1, 2 blister packs of 5 tablets each or 1 blister pack of 10 tablets, together with instructions for use of the medicinal product, are placed in a cardboard pack.

Description of the dosage form

Vaginal tablets

Characteristic

Tablets are white or white with a yellowish tint, biconvex, oblong. Slight marbling of the surface is allowed.

Directions for use and doses

Intravaginally. Before use, it is recommended to moisten the tablet in water.

For treatment: 1 vaginal tablet 1-2 times a day for 7-10 days.

To prevent sexually transmitted infections: 1 vaginal tablet no later than 2 hours after unprotected intercourse.

If symptoms persist for more than 7 days, it is recommended to consult a doctor.

Use the drug only according to the method of use and in the doses indicated in the instructions for use. If necessary, please consult your doctor before using the medicine.

Pharmacodynamics

A local antiseptic with a predominantly bactericidal effect against gram-positive and gram-negative bacteria, and has a fungicidal and virucidal effect (against lipophilic viruses). Active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex type 2. Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, and acid-resistant forms of bacteria and bacterial spores are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of blood and pus.

Pharmacokinetics

Systemic absorption after intravaginal use is negligible.

Indications for use Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

Treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonas).

Prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth and abortion, before and after installation of an intrauterine device (IUD), before and after diathermocoagulation of the cervix, before intrauterine examinations).

Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes) - use no later than 2 hours after sexual intercourse.

Contraindications

Hypersensitivity to chlorhexidine and other components of the drug, children under 18 years of age.

Application Hexicon 16 mg 10 pcs. Nizhpharm vaginal tablets during pregnancy and breastfeeding

The use of the drug during pregnancy and breastfeeding is possible only after a careful assessment of the expected benefit to the mother and the risk to the fetus and child.

special instructions

In childhood, it is recommended to use the drug Hexicon® D.

Overdose

Cases of overdose are unknown. When using the drug in accordance with the instructions for use, an overdose is unlikely.

Side effects Hexicon 16 mg 10 pcs. vaginal tablets nizhpharm

Allergic reactions and vaginal itching are possible, which disappear after discontinuation of the drug.

Severe allergic reactions, including anaphylaxis.

If any of the side effects indicated in the instructions get worse or you notice any other side effects not listed in the instructions, tell your doctor.

Drug interactions

Concomitant use with iodine-containing drugs used intravaginally is not recommended.

Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally.

Compatible with drugs containing a cationic group (benzalkonium chloride, cetrimonium bromide).

Can Hexicon be used by pregnant women?

The drug Hexicon in any form (except vaginal tablets) can be given during pregnancy. The drug does not pose any threat to the fetus and the expectant mother.

During pregnancy, if there are gynecological problems, women are more often prescribed suppositories. The harmlessness of the drug is explained by its local action. This is evidenced by many years of experience. The active components do not enter the blood, which does not pose a threat to the developing fetus. Candles can be used at any month of pregnancy.

Is it possible to use Hexicon while breastfeeding?

The medication in any form (with the exception of vaginal tablets) can be given during lactation.

The active ingredients do not enter the blood or milk, so they do not pose any threat to the baby.

A specialist may prescribe vaginal tablets during pregnancy and breastfeeding in rare cases, if the expected benefit is several times greater than the possible risk.

Under no circumstances should you self-medicate while pregnant. Before taking it, be sure to consult a specialist.

Hexicon

Hexicon (INN chlorhexidine bigluconate) is a local antiseptic drug for use in gynecological practice from the Russian pharmaceutical company. Used to prevent genitourinary tract infections in women. Patients of this profile account for about 60% of all visits to the gynecologist. Inflammatory infections can lead to non-hormonal infertility, ectopic pregnancy, miscarriages, and abnormalities in fetal development. Hexicon is an over-the-counter drug that is widely in demand today both as a means of prevention and as a tool for the effective treatment of sexually transmitted infections. The main pathogenic “residents” of the female genitourinary tract are Trichomonas, chlamydia, ureaplasma, mycoplasma, and gonococci. Relief of infectious processes in the genital tract is complicated today by the increased aggressiveness of opportunistic microflora, the widespread phenomenon of drug resistance to antimicrobial drugs, the tendency to reduce the immune status in the general population, and untimely and incorrect diagnosis. The antimicrobial and antiseptic drug Hexicon is distinguished by its speed and breadth of therapeutic action, the scope of which includes bacteria such as Trihomonas vaginalis, Ureaplasma spp., Chlamidia spp., Treponema pallidum, Neisseria gonorrhoeae. Available in dosage forms for local use: vaginal tablets, suppositories, solutions. The advantage of local treatment of sexually transmitted infections is minimizing the risk of developing undesirable side reactions (the vast majority of which are systemic in nature), ease of use, the possibility of use by patients with extragenital (extragenital) pathology, primarily with a localized infectious-inflammatory process (for example, with acute vaginitis, cervicitis, vulvitis or chronic processes in the acute stage).

Hexicon can become a means of emergency prevention of sexually transmitted diseases immediately after unprotected sexual intercourse (but no later than two hours after it). Hexicon has been well studied in several clinical studies conducted in Russia. Thus, in one of them its effectiveness in the treatment of infectious vaginosis was reliably confirmed: 5-7 days of use was enough to normalize the vaginal microflora. The effect of Hexadecone on the microbial biotope of the vagina in women of childbearing age with bacterial vaginosis in the relapse stage was also studied. As a result, the antimicrobial activity of the drug against aerobic and anaerobic microflora and its good therapeutic effect in patients with bacterial vaginosis were established. Chlorhexidine does not affect the functional activity of lactic acid bacteria. The drug retains its antimicrobial activity in the presence of biological fluids (blood, pus). As already noted, Hexicon has only local side effects in the form of rare allergies to chlorhexidine. Pregnancy and breastfeeding are not contraindications to the use of the drug. Hygienic procedures for the external genitalia do not affect the activity and tolerability of Hexicon, since the drug is used intravaginally. No cases of chlorhexidine overdose have been reported to date.

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