Chlorhexidine bigluconate Solution, bottle, 100 ml, 0.05%, for external use

What is Chlorhexidine used for?

An aqueous solution is prescribed to be taken in the following cases:

• cervical erosion;
• for the prevention of syphilis, genital herpes and other vaginal diseases;
• disinfection of dentures, disinfection of wounds;
• various diseases of the oral cavity.

An alcohol solution is used to treat hands and medical devices before surgery. The solution is also used to treat the working surface of medical equipment.

Vaginal suppositories are effective for the following conditions:

• in order to prevent infections that can be transmitted as a result of unprotected sexual intercourse;
• bacterial vaginosis;
• prevention of inflammation and infections before surgery, childbirth or abortion.

How to use Chlorhexidine in gynecology

The product is actively used to prevent sexually transmitted diseases. No later than 2 hours after unprotected intercourse, you need to take the solution. Men will need to insert 2 ml into the urinary canal, and women will need to insert 2 ml into the urinary canal and another 5-7 ml into the vagina. It is recommended to wipe the skin around the genitals with the solution. The instructions say that after using the drug you need to wait 2 hours before urinating. Otherwise, the effect of use will be less.

For preventive purposes, vaginal suppositories can be used.

Before using the product for thrush and other gynecological pathologies, you should consult a specialist in advance.

Chlorhexidine bigluconate solution 0.5 mg/ml 100 ml

Name

Chlorhexidine bigluconate.

Description

Transparent, colorless or slightly yellowish liquid, odorless.

Main active ingredient

Release form

Solution for external use.

Dosage

0.05% 100 ml.

pharmachologic effect

An antiseptic with a pronounced bactericidal effect against gram-positive and gram-negative bacteria (does not affect acid-fast forms of the latter): Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis, protozoa (Trichomonas vaginalis), microbial spores , viruses, fungi; has little effect on some species of Proteus and Pseudomonas. Chlorhexidine bigluconate is also active against treponemas, gonococci, and trichomonas. Retains activity (slightly reduced) in the presence of blood and pus. Cleanses and disinfects the skin without causing damage.

Indications for use

The drug is used for the prevention of sexually transmitted diseases (syphilis, gonorrhea, trichomoniasis, chlamydia, etc.). It is used for antiseptic treatment of wounds, abrasions and cracks, burns, for bacterial and fungal diseases of the skin and mucous membranes, incl. in urology, surgery, obstetrics and gynecology. In dentistry, it is used for rinsing the mouth in cases where compliance with hygiene rules is difficult, in the postoperative period after flap periodontal surgery, for washing periodontal pockets, fistulas, and abscess cavities. Since chlorhexidine bigluconate has a cytotoxic effect, the concentration of the rinse solution should not exceed 0.25 mg/ml.

Directions for use and doses

The drug is used in the form of irrigation, rinsing and application - 5-10 ml of solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times a day (on a tampon or by irrigation). For the prevention of sexually transmitted diseases, the drug is effective if used no later than 2 hours after sexual intercourse. Used after urination: using a nozzle, insert into the urethra for men (2-3 ml), for women into the urethra (1-2 ml) and into the vagina (5-10 ml) and hold for 2-3 minutes. Treat the skin of the inner thighs, pubis, and genitals. After the procedure, it is not recommended to urinate for 2 hours. Complex treatment of urethritis and urethroprostatitis is carried out by injecting 2-3 ml of the drug into the urethra 1-2 times a day, the course is 10 days, procedures are prescribed every other day. The rinse solution is usually prescribed 2-3 times a day (for rinsing the mouth, the drug should be mixed with an equal amount of water).

Use during pregnancy and lactation

Use with caution in pregnant and lactating women due to the lack of data on experience with clinical use. Do not treat the surface of the mammary glands before feeding.

Precautionary measures

The bactericidal effect increases with increasing temperature. At temperatures above 100 °C, the drug is partially decomposed. Contact of hypochlorite bleaches on fabrics that have previously been in contact with chlorhexidine-containing products may cause brown stains. In patients with open traumatic brain injury, spinal cord injuries, or perforation of the eardrum, contact with the surface of the brain, meninges, and the cavity of the inner ear should be avoided. In case of contact with the mucous membranes of the eyes, they should be quickly and thoroughly rinsed with water. Concomitant use with iodine is not recommended. Use in children. The use of chlorhexidine solution (aqueous or alcoholic) in newborns as a skin antiseptic before invasive procedures is associated with a certain risk of developing a chemical burn. Based on spontaneous reporting and literature data, a higher risk of skin reactions has been identified in preterm neonates, particularly those born before 32 weeks of gestation, in whom chlorhexidine was used during the first two weeks of life. Before performing invasive procedures, it is necessary to remove all materials soaked in chlorhexidine: bandages, sheets, napkins, gowns, etc. Do not use excessive amounts of solution. The solution should not be allowed to accumulate in skin folds, under the patient’s body, or on materials that are in direct contact with the child’s skin. If an airtight dressing (occlusive dressing) is to be applied to skin that has previously been exposed to chlorhexidine, ensure that there is no excess chlorhexidine solution on the skin before applying the dressing. Use in elderly people. There are no data regarding the specifics of use in elderly patients.

Interaction with other drugs

Not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose). Concomitant use with iodine is not recommended. The presence of soap can inactivate chlorhexidine digluconate, so before using the drug, any remaining soap must be thoroughly rinsed off. Ethanol enhances the effectiveness of the drug.

Contraindications

Hypersensitivity, dermatitis, viral skin diseases, age up to 12 years. It is not recommended for use on large surface wounds.

Compound

A 40 ml bottle contains: active ingredient: chlorhexidine bigluconate (in the form of dezine (chlorhexidine bigluconate 20% solution)) – 20 mg; excipient: purified water – up to 40 ml. A 100 ml bottle contains: active ingredient: chlorhexidine bigluconate (in the form of dezine (chlorhexidine bigluconate 20% solution)) – 50 mg; excipient: purified water – up to 100 ml. A 200 ml bottle contains: active ingredient: chlorhexidine digluconate (in the form of dezine (chlorhexidine digluconate 20% solution)) – 100 mg; excipient: purified water – up to 200 ml.

Overdose

Cases of overdose with external use are unknown. When ingested, the drug is practically not absorbed, so systemic effects are unlikely. However, in case of accidental ingestion, gastric lavage is necessary. If necessary, carry out symptomatic therapy.

Side effect

Possible allergic reactions (skin rash), dryness and itching of the skin, dermatitis, photosensitivity, stickiness of the skin of the hands (within 3-5 minutes), chemical burns of newborns (frequency unknown). In the treatment of gingivitis – staining of tooth enamel, tartar deposits, taste disturbance. If any adverse reactions occur, including those not listed in these instructions, you should consult a doctor.

Storage conditions

Store at a temperature not exceeding 25 °C. Keep out of the reach of children.

Buy Chlorhexidine bigluk solution d/nar.prim.0.5 mg/ml fl 100 ml in the pharmacy

Price for Chlorhexidine bigluk solution d/nar.approx. 0.5 mg/ml fl 100 ml

Instructions for use for Chlorhexidine bigluk solution d/nar.approx. 0.5 mg/ml fl 100 ml

Contraindications and adverse reactions

Taking the drug is contraindicated in the following cases:

• increased susceptibility to the components included in the composition;
• patients with dermatitis;
• simultaneous use with other antiseptics, for example, hydrogen peroxide;
• in ophthalmology for washing the eyes.

It is better to refrain from using the product to disinfect the surgical field before or after surgery on the central nervous system and auditory canal.

In pediatrics, the drug is used with great caution.

Some patients may experience undesirable reactions such as:

• dry skin;
• allergic skin rashes;
• itching of the skin;
• light sensitivity.

With prolonged use of the product in dentistry, changes in taste may occur, tartar may appear, or teeth may become stained.

Modern Pharmaceuticals of Russia

Chlorhexidine bigluconate 0.05% 100 ml

APPLICATION
The product is intended for use in medical institutions: hygienic treatment of the hands of medical personnel, including ambulance personnel; cleaning the hands of surgeons, operating nurses, midwives and other persons involved in operations and childbirth; hygienic treatment of the hands of medical personnel of medical institutions, the hands of medical workers of preschool and school institutions, social security institutions.

And also for the hygienic treatment of hands of students in educational institutions;
hygienic treatment of hands of workers of perfumery, cosmetics, chemical and pharmaceutical enterprises, public utility facilities; workers of food enterprises, public catering enterprises and food trade enterprises. Hygienic treatment of hands of workers of poultry, livestock, pig and fur farms; hand treatment for the population, protection from microbes in public places, in nature, and also as a prophylactic agent in the form of irrigation, rinsing and applications on the surface of the skin and mucous membranes. PACKAGING
Packaging is carried out in 25 ml, 50 ml, 100 ml in orange glass bottles with a screw neck, sealed with polyethylene stoppers and screw caps.

25 ml, 50 ml, 100 ml, 200 ml, 500 ml, 1000 ml in high-pressure polyethylene bottles with a polymer nozzle or a special nozzle with a screw cap, or equipped with a spray pump and a protective polyethylene cap.

5 l, 10 l, 20 l in canisters made of low-density polyethylene (for hospitals).

Glass bottles of 25 ml, 50 ml, 100 ml are placed in boxes with partitions or corrugated cardboard bars.

Bottles of 25 ml, 50 ml, 100 ml, 200 ml, 500 ml, 1000 ml made of high-density polyethylene should be packaged in polyethylene shrink film or in a box with partitions or grids made of corrugated cardboard.

Polyethylene canisters are placed in a wooden pallet, no more than 2 rows high, and covered with stretch film.

BARCODES
Individual

Group

INSTRUCTIONS for using the disinfectant
Registration number:

RU.77.99.01.002.E.031065.08.11

Trade name of the drug:

Chlorhexidine bigluconate 0.05% – YuzhPharm

International nonproprietary name:

Chlorhexidine

Form:

Colorless or light yellow transparent liquid.

Compound:

chlorhexidine bigluconate, 0.05%, purified water.

Description:

"Chlorhexidine bigluconate 0.05% - YuzhPharm" is a ready-to-use product in the form of a clear or slightly opalescent liquid, colorless or light yellow, odorless or with a faint odor.

Group:

Disinfectant.

PROPERTIES:

The product is bactericidal against gram-positive and gram-negative bacteria (including pathogens of nosocomial infections), tuberculocidal, virucidal (acute respiratory viral infections, herpes, polio, hepatitis of all types, including hepatitis A, B and C, HIV infection, adenovirus etc.) and fungicidal (against fungi of the genera Candida and Trichophyton) action. According to the parameters of acute toxicity, “Chlorhexidine bigluconate 0.05% - YuzhPharm” belongs to class 4 of low-hazardous substances according to GOST 12.1.007-76 when applied to the skin, introduced into the stomach and inhaled. According to the classification of Sidorov K.K. when administered parenterally, the drug belongs to class 5 of practically non-toxic compounds. Skin-resorptive and sensitizing properties in the recommended modes of use of the product have not been identified. The product has a moderate irritating effect on the mucous membranes of the eyes. The maximum permissible concentration in the air of the working area of ​​chlorhexidine bigluconate is 1 mg/m3.

The product can be used to treat the skin of children from birth.

INDICATIONS FOR USE:

The product "Chlorhexidine bigluconate 0.05% - YuzhPharm" is intended for use in medical institutions:

• for hygienic treatment of the hands of medical personnel, including personnel of ambulances;
• for disinfecting the skin of the injection field;
• for sanitary treatment of the skin and the skin of the feet to prevent fungal diseases;
• for disinfection of rubber gloves worn by personnel (made of materials resistant to chemicals) during surgical interventions and manipulations requiring surgical antiseptics, when working with potentially infected material (microbiological and other laboratories); when collecting medical waste of classes B and C.
• for disinfection of small instruments of simple configuration;
• as a prophylactic agent in the form of irrigation, rinsing and application on the surface of the skin, mucous membranes;
• for hygienic treatment of hands of students of general education institutions, staff of preschool and school institutions, social security institutions (nursing homes, hospices, etc.), employees of perfumery and cosmetics enterprises (including hairdressers, beauty salons, etc.), public food, communal facilities, food and chemical-pharmaceutical industries;
• for hygienic treatment of the skin of the hands, injection field, sanitary treatment of the skin and skin of the feet for the purpose of preventing fungal diseases, as a prophylactic for the population in everyday life.

CONTRAINDICATIONS:
Skin-resorptive and sensitizing properties have not been identified in the recommended modes of use.
The product has a moderate irritant effect on the mucous membranes of the eyes. HOW TO USE:
Hand hygiene:

3 ml of the product is applied to the hands and rubbed into the skin until dry for 30 seconds.

Treatment of the injection field, incl. at the vaccination site:

the skin is wiped with a sterile cotton swab or irrigated until completely moisturized, followed by holding for 30 seconds.

Preventive treatment of the feet, sanitary treatment of the skin:

With a generously moistened cotton swab, thoroughly treat each foot or area of ​​skin with different cotton swabs or irrigate with the product until the skin is completely moisturized, holding time for at least 30 seconds.

Processing of gloves worn by personnel:

The outer surface of the gloves is thoroughly wiped with a sterile swab, generously moistened with the product. Processing time – at least 1 minute. Exposure - until the surface of the gloves is completely dry.

Small tools of simple configuration:

(in healthcare facilities, beauty salons, hairdressing salons, manicure and pedicure rooms, etc.) must be completely immersed in the product immediately after its use. The thickness of the layer of product over the products must be at least 1 cm. After the disinfection period of 5 minutes is completed, the products are removed from the container and washed with running drinking water for at least 1 minute.

As a prophylactic agent in the form of irrigation, rinsing and application - 5-10 ml of solution is applied to the surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times a day (on a tampon or by irrigation).

SPECIAL INSTRUCTIONS:

Use for external use only. Do not use the product after the expiration date. If the product accidentally gets into the stomach, it is recommended to drink several glasses of water with the addition of an adsorbent (for example, 10-15 crushed tablets of activated carbon per glass of water). Do not induce vomiting! If necessary, seek medical help.

RELEASE FORM:

The product is packaged in 25 ml, 50 ml, 100 ml in orange glass bottles. 25 ml, 50 ml, 100 ml, 200 ml, 500 ml, 1000 ml in high-pressure polyethylene bottles with a polymer nozzle, or with a special nozzle with a screw cap, or equipped with a spray pump and a protective polyethylene cap. 5 l each; 10 l; 20 liters in low-density polyethylene canisters (for hospital use).

STORAGE AND TRANSPORTATION CONDITIONS:

Store in tightly closed manufacturer's packaging at temperatures from 0 ºС to +30 °С; away from sources of heat and fire; Avoid storage in direct sunlight. No smoking! Store separately from medications, out of the reach of children. Transportation by any means of transport is allowed in accordance with the rules for the carriage of goods in force for this type of transport, at temperatures from 0 ° C to +30 ° C.

BEST BEFORE DATE:

The product's shelf life is 2 years in unopened manufacturer's packaging.

CONDITIONS FOR DISCHARGE FROM PHARMACIES:

Over the counter.