Trigan D is a common drug among teenagers.

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Attention! The material contains information about substances, the use of which can cause serious harm to your health!

Article prepared by an expert

Egorova Yulia Viktorovna

Psychologist, diagnostician, author of rehabilitation programs for addicts. Member of the Association of Cognitive Behavioral Psychotherapy. More than 7 years of experience working with addicts and their families.

Reading time: 4 minutes

Read in the article:

1. Purpose of the drug
2. Use of Trigan-D by drug addicts
3. Signs of intoxication
4. How addiction develops
5. Health implications
6. First aid and addiction treatment

The drug Trigan-D is a pain reliever, but in case of overdose it has side effects that attract drug addicts. The easy availability of the drug for different segments of the population has caused a surge in consumption, which is why many experts are calling for the drug to be classified as a narcotic. What effect Trigan-D has on the human body, how addiction develops and how to treat it, read our article.

Pharmacodynamics and pharmacokinetics

There is no information about Trigan-D on Wikipedia, and the interested category of people have questions “Trigan-D, what is it?” or “What is Trigan-D?”

The first component is paracetamol : it has an antipyretic, analgesic and weak anti-inflammatory effect. Inhibits cyclooxygenase of the first and second types in the nervous system and other tissues, as a result, the synthesis of prostaglandins - mediators of pain, regulation of body temperature and inflammation - stops.

The second component is dicycloverine hydrochloride : it has a small non-selective m-anticholinergic and myotropic antispasmodic effect on the smooth muscle cells of internal organs. In therapeutic doses, it has a relaxing effect on smooth muscles, not accompanied by atropine-like side effects.

The combined use of these two components allows for relaxation of the smooth muscle tissue of internal organs and relief of pain.

Pharmacokinetics

Well absorbed from the intestines. The maximum concentration in the blood is recorded after one hour. Paracetamol is transformed in the liver to form a number of metabolites, one of them N-acetyl-benzoquinomine can have a damaging effect on the kidneys and liver. 80% of the drug is excreted by the kidneys and in small amounts with feces.

Consequences and first aid for overdose

Negative reactions occur even when the medication is used in therapeutic doses. This is due to the fact that the drug has a depressant effect on the central and peripheral nervous system. There are difficulties with swallowing, severe thirst, constipation, vomiting. A person feels drowsiness, attacks of dizziness, and sometimes there are problems with urination and bowel movements. In case of an overdose, the condition of the addict is much worse.

Side effects from overdose:

• chills, fever;
• schizophrenic delusion;
• convulsions, paralysis;
• complete or partial loss of vision;
• euphoria gives way to drowsiness;
• repeated vomiting;
• respiratory dysfunction;
• memory losses;
• chronic constipation;
• disturbances in the functioning of the heart, bradycardia is replaced by tachycardia;
• exhaustion due to lack of appetite;
• dermatological diseases;
• kidney and liver failure;
• internal bleeding;
• urinary and fecal incontinence against the background of severe relaxation of the visceral muscles;
• coma, cardiac arrest, renal necrosis - these pathologies lead to the death of the patient.

If dangerous symptoms appear, you should call an ambulance. Before doctors arrive, perform gastric lavage or induce vomiting, give activated charcoal at the rate of 1 tablet per 10 kg of weight. The patient needs to be seated or laid on his side, not allowed to sleep, and ensure that he is conscious. The doctor will put on a drip with enterosorbents, drugs to restore the functions of the nervous system, and hepatoprotectors. Be sure to administer an antidote - methionine and acetylcysteine. Then the patient requires hospitalization.

How much do you need to drink to overdose? A dangerous dose is 5-6 tablets. This amount is sufficient for the development of pathological, dangerous processes in the body.

Even small doses of alcohol increase the danger of the drug. When Trigan-D and alcohol are consumed together, irreversible damage occurs in the liver, and the thermal stage of renal failure quickly develops.

Indications for use

Indications for use (for which Trigan-D tablets are usually used):

• spasm of smooth muscle internal organs;
• algomenorrhea;
• hepatic, intestinal or renal colic ;
• neuralgia;
• toothache or headache ;
• myalgia;
• fever in infectious and inflammatory diseases .

Content:

1. Description of the drug
2. Narcotic effect
3. Consequences and first aid for overdose
4. What to do if drug addiction is detected

Trigan-D is a drug with a combined effect, an antispasmodic and analgesic. This is a non-narcotic substance, but it is persistently addictive ; with long-term use, severe side effects occur.

Contraindications

• Sensitization to paracetamol or dicycloverine .
• Stomach or duodenal ulcer.
• Intestinal diseases complicated by obstruction.
• Hypovolemic shock.
• Reflux esophagitis.
• Myasthenia gravis.
• Lactation and pregnancy .
• Age less than 15 years.

The components of the drug in patients with liver or kidney disorders, glucose-6-phosphate dehydrogenase , glaucoma , blood diseases, hyperbilirubinemia, viral hepatitis, alcoholism and in old age can worsen the course of these diseases, from which Trigan-D tablets should be used in this category of people with extreme caution.

What to do if you have drug addiction

All forms and analogues of Trigan D are drugs that are dangerous due to their imaginary harmlessness. Psychological dependence on the drug develops, which cannot be completely eliminated by traditional drug courses of treatment designed for 12 or 28 days.

The Narconon social adaptation program is radically different from them. Drug addicts taking Trigan D do not receive drug treatment, which is especially important for psychological dependence. The program includes stages that eliminate the causes and consequences of addiction and return the patient to normal social life:

• communication skills are restored;
• a clear outlook on life is gained;
• a person acquires the skill of understanding people, distinguishing friends from enemies;
• a person realizes his obligations, stops looking for a return to the past, feels the desire to get Trigun D, ​​buy it;
• the skill of creative problem solving in life is formed.

After completing the last stage, the patient receives tools that will allow him to give up the drug forever. The technique helps overcome addiction and maintain the positive effect forever.

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Side effects

• Reactions from the digestive system: distortion of taste, stomach pain, decreased appetite, increased levels of liver enzymes , constipation, hepatonecrosis.
• Reactions from the nervous system: dizziness , drowsiness , agitation and disorientation.
• Allergic reactions: Quincke's edema , rash , urticaria , Stevens-Johnson syndrome, itching , Lyell's syndrome.
• Reactions from the hormonal system: hypoglycemia.
• Reactions from the excretory system: interstitial nephritis, urinary retention, pyuria , papillary necrosis , decreased potency.
• Reactions from the hematopoietic system: methemoglobinemia, hemolytic anemia.
• Reactions from the vision: mydriasis, paralysis of accommodation, blurred vision, increased intraocular pressure.

Trigan-D tablets, instructions for use (Method and dosage)

Instructions for use on Trigan-D recommend taking the drug orally, 1 tablet up to three times a day. The largest single dose is two tablets, the daily dose is four tablets. Duration of administration is no more than five days when used as an analgesic and three days when used as an antipyretic.

It is not recommended to exceed the daily dose, since an overdose of the drug causes liver failure, for which Trigan-D (if it is necessary to increase the dose or increase the standard duration of treatment) must be used under the supervision of a physician.

How addiction develops

Trigan-D blocks pain centers and reduces pain after surgery. Taking a small dose, the addict experiences relaxation and euphoria. At the same time, the drug causes irreversible changes in the human body. By acting on pain receptors, it suppresses their functioning, and the negative consequences of use are felt only when the drug is discontinued.

First, a person gets used to psychologically relaxing by taking pills. And when a small dose ceases to bring the same pleasure, it increases the amount of substance consumed. At the same time, an overdose, as well as refusal to take the medicine, lead to negative symptoms. This is how a person falls into the trap of addiction.

Overdose

Overdose of Trigan-D, symptoms: tachypnea, tachycardia, fever, convulsions, agitation, pain in the stomach, decreased appetite, thrombocytopenia, anemia, nephrotoxicity, hemolytic or aplastic anemia, pancytopenia, methemoglobinemia, hepatonecrosis.

Therapy: stop using the drug, perform gastric lavage, take adsorbents , agents that stimulate the formation of glutathione (for example, acetylcysteine ) and activate conjugation ( methionine ).

Consequences of excessive use of “pharmacy drugs”

Trigan-D is an excellent remedy against severe pain and spasms. However, with constant abuse of the drug, a person may face consequences that include:

• Deterioration or complete loss of vision.
• Liver pathologies.
• Paralysis of limbs.
• Acute renal failure.
• Cardiac arrhythmias.
• The appearance of gastrointestinal bleeding.
• Dry skin.
• Urinary incontinence.

When using Trigan-D with other similar drugs, such as Lyrica, alcohol or marijuana, there is a high likelihood of anaphylactic reactions or falling into a coma. In some rare cases, death is possible.

Interaction

The effects of dicycloverine are stimulated by first class antiarrhythmic drugs benzodiazepines, narcotic painkillers, MAO inhibitors, sympathomimetics, nitrates, nitrites, tricyclic antidepressants.

Dicycloverine increases the level of dioxin in the blood.

Enhancers of microsomal oxidation ( ethanol, barbiturates, rifampicin, tricyclic antidepressants ) stimulate the synthesis of hydroxylated metabolites in the liver, this can lead to the development of severe intoxication even with mild overdoses of paracetamol .

Inhibitors of microsomal oxidation reduce the possibility of hepatotoxicity .

Adrenergic stimulants and anticholinergic drugs increase the risk of unwanted effects.

Paracetamol activates the action of indirect anticoagulants.

Analogs

Level 4 ATC code matches:
Phenacetin

Combiflu

Chlorphenamine

Coldflu

Calpol

Fervex

Panadol Extra

Panadol for children

Panadol

Solpadeine

Efferalgan

Milistan

Coldrex Maxgripp

Coldrex Hotrem

Coldrex

AntiGrippin

Unispaz

Pentalgin Plus

Rapidol

Maxicold

Duspatalin, Mebsin Retard, Moreaze SR, Trimpa.

Reviews about Trigan-D

According to reviews, the product helps to effectively relieve spasms and pain in the vast majority of cases.

paracetamol are also known . As a result, after consuming the resulting substance, side effects occur on the psyche and nervous system, called “highs.” You should know that this is an extremely harmful effect that can lead to irreparable consequences. On specialized forums, you often encounter questions like “how to remove paracetamol from Trigan to get the drug?” We strongly advise you not to engage in such experiments with medications and your body.

Trigan D effect and the emergence of drug addiction

The main effect of the drug and its analogues is analgesic. When the therapeutic dose is exceeded, mild euphoria is observed; in severe cases, hallucinations are observed, which outwardly look like schizophrenic delusions. Drug addicts call the effect caused by Trigan D a “trip” - by analogy with synthetic hallucinogenic drugs.

Dicyclomine is maximally concentrated in plasma one to one and a half hours after taking the tablets, and paracetamol after 30 minutes. The peak effect is observed 2 hours after receiving the drug. Drug addicts who take Trigan “see” realistic pictures, not always positive and colorful. People addicted to the drug talk to non-existent interlocutors, they begin to become paranoid and panic.

Trigan is a drug that is common among teenagers and schoolchildren (there it is called “trigande”, “triganda” or “trigana”). It is easy to get, it is inexpensive, and is sold in almost all pharmacies. Dicycloverine (the drug has an effect primarily due to its presence) is isolated from tablets in home or “clandestine” conditions to enhance its effect. This is how addiction is formed, which inevitably destroys the organs and psyche. Trigan D is a potent anticholinergic that affects neurotransmitters in the brain, and the consequences of its use are unpredictable - including mental illness, liver failure and coma.

Trigan-D price, where to buy

The average price of Trigan D No. 100 in Ukraine is 302 hryvnia, and in Russia – 316 rubles.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine

ZdravCity

• Trigan-D tablets 500 mg 100 pcs. Cadila Pharmaceuticals Ltd.
  RUB 341 order
• Trigan-D tablets 500 mg 20 pcs. Cadila Pharmaceuticals Ltd.

  97 RUR order

• Trigan-D tab. No.10Cadila Pharmaceuticals Ltd.

  68 RUR order

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Trigan D - description and properties of the drug

The drug Trigan D belongs to the pharmacological group of antispasmodic and analgesic drugs. This medication has a complex effect on the human body, provoking the development of a pronounced pathological dependence and numerous side effects.

Teenagers especially value Trigan D for its ability, when used in large doses, to change the state of consciousness and cause hallucinations. Moreover, to purchase medicine at a pharmacy you do not need a doctor’s prescription, and its cost is quite affordable and affordable.

Trigan D is a truly high-quality and effective drug that quickly relieves pain. When used in large doses, on a regular basis, without the advice of a specialist, it turns into a dangerous drug.