What does it consist of?
Medicine for pain is available in several forms:
- powder from which it is easy to prepare a suspension;
- pills;
- cream.
The powder is available in a dosage of three grams. Typically sold in packs of twenty bags.
Tablets of one hundred milligrams, sold in packs of twenty and sixty tablets. Uniform white ointment in a sixty gram package.
The main active ingredient is aceclofenac.
When is it prescribed?
The medicine is used for the following conditions:
- toothache;
- rheumatoid arthritis;
- osteoarthritis;
- periarthritis;
- sciatica;
- rheumatism;
- heat;
- periodic pain during menstruation in women;
- cold;
- flu;
- inflammation of various etiologies;
- pain syndrome.
Aertal ointment is prescribed for:
- bruises;
- sprains;
- dislocations;
- torticollis;
- myositis;
- tendinitis;
- periarthritis;
- sciatica;
- Tenosynovitis.
The product is quite effective, helps quickly, permanently eliminates pain, and reduces temperature. However, it is not always safe. Nonsteroidal anti-inflammatory drugs have a wide range of contraindications. They are especially dangerous for people with gastrointestinal diseases. "Aertal" should be used carefully, having read the instructions before use.
What is Aertal powder from?
Powder is a type of dosage form. It is intended for preparing a suspension. A single dose of the drug is packaged in a sachet. The advantage of using the powder is its rapid absorption. The tablet requires time to be broken down and processed in the gastrointestinal tract, and the powder, once in the stomach, begins to be absorbed into the blood without waiting for delivery to the intestines. The active substance contained in the tablets is contained in the same volume in one sachet.
Another advantage of using powder is the ability to accurately adjust the dose. For example, people with kidney or liver failure need to reduce the single dose by half. By dividing the contents of the package into two parts, it is easy to prepare a suspension of the desired concentration.
Who should not be prescribed
"Aertal" is contraindicated in the following conditions:
- peptic ulcer of the stomach and duodenum;
- gastritis in the acute phase;
- allergic manifestations;
- poor blood clotting;
- liver diseases;
- kidney inflammation;
- heart failure;
- minor patients;
- pregnancy.
The ointment is not used for external skin lesions, as well as allergic rashes.
Aertal or Xefokam: which is better?
Ksefokam, like Airtal, is an anesthetic drug. Its activity is primarily observed in rheumatoid arthritis, osteoarthritis and other types of joint and bone pain. However, unlike Airtal, Xefocam is based on another active substance - lornoxicam, which does not in any way affect the level of inflammation and the patient’s body temperature. The drug is suitable for symptomatic use and relief of sudden pain.
Adverse reactions for both drugs are identical. Long-term use can cause anemia, thrombocytopenia, insomnia, and depression. When choosing between medications, you need to pay special attention to individual intolerance to the components, and the need to relieve inflammation and normalize the temperature.
Both drugs are contraindicated during pregnancy and breastfeeding, since their active ingredients are instantly and almost completely absorbed into the blood. These drugs are also not prescribed to patients under 18 years of age. Bronchial asthma is a direct contraindication to the use of both drugs, since both of them can cause bronchospasm.
Side effects
Sometimes during treatment with Aertal, undesirable effects appear.
They are expressed as:
- nausea and vomiting;
- ulcerative lesions of the stomach and intestines;
- decreased appetite;
- diarrhea or constipation;
- liver failure;
- headache;
- tremors of the limbs;
- emotional lability;
- overexcitement;
- hearing and vision disturbances;
- kidney dysfunction;
- swelling;
- heart rhythm disturbances;
- hypertension;
- allergic reactions;
- hives;
- Quincke's edema;
- anaphylactic shock.
It is necessary to take the drug very carefully if you have existing stomach problems, as life-threatening gastric bleeding is likely to develop.
Sometimes when taking Aethral, photosensitivity reactions on the skin may occur.
Instructions for use AIRTAL®
Adverse reactions can be minimized by using the lowest effective dose and reducing the duration of treatment to achieve symptom control.
The simultaneous use of Airtal and other NSAIDs, including selective COX-2 inhibitors, should be avoided.
Effect on the gastrointestinal tract
Bleeding, ulceration or perforation of the gastrointestinal tract with a fatal outcome was observed when taking any NSAIDs during any period of treatment, both with and without dangerous symptoms, both with and without a history of serious pathological conditions of the gastrointestinal tract.
The risk of bleeding, ulceration and gastrointestinal perforation increases with increasing dose of NSAIDs in patients who have had an ulcer, especially if it was accompanied by hemorrhage or perforation, and in elderly patients. In such cases, the drug should be taken in the minimum effective dose. In addition, these patients require combination therapy with drugs that have a protective effect on the gastrointestinal tract (for example, misoprostol, or proton pump inhibitors). Such therapy is necessary for patients who take small doses of acetylsalicylic acid (aspirin) or other drugs that negatively affect the gastrointestinal tract.
Patients with gastrointestinal diseases, as well as elderly patients, should report any unusual symptoms associated with the gastrointestinal tract (especially bleeding), incl. when taking the drug for the first time. Particular caution should be exercised when using Airtal in patients concomitantly receiving drugs that may increase the risk of bleeding or ulceration, such as systemic corticosteroids, anticoagulants (such as warfarin), selective serotonin reuptake inhibitors, or antiplatelet agents (such as acetylsalicylic acid).
If bleeding or gastrointestinal ulcers occur while taking Airtal, the drug should be discontinued.
Effect on the cardiovascular system and central nervous system
For patients with hypertension and/or mild to moderate congestive heart failure, appropriate monitoring and special precautions are required because Fluid retention and edema associated with NSAIDs have been reported.
Clinical studies and epidemiological data indicate that the use of some NSAIDs (particularly at high doses and for long periods of time) may not significantly increase the risk of arterial thrombotic events (eg, myocardial infarction or stroke). There is no reliable data on the absence of this risk when taking aceclofenac.
Particular caution should be exercised when using Airtal in patients with uncontrolled arterial hypertension, heart failure (NYHA functional class I), congestive heart failure, with risk factors for the cardiovascular system (for example, arterial hypertension, hyperlipidemia, diabetes mellitus and smoking ).
Aceclofenac should be prescribed with caution and under medical supervision to patients with the following conditions, because: there is a threat of exacerbation of the disease:
- symptoms indicating the presence of gastrointestinal disease, including its upper and lower sections;
- a history of ulcers, bleeding or perforation of the gastrointestinal tract;
- Crohn's disease;
- bleeding tendency, SLE, porphyria, and disorders of hematopoiesis and hemostasis.
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ulcerative colitis;
The drug should be used with caution and under medical supervision in patients with a history of hemorrhagic stroke.
Effect on the liver and kidneys
Taking NSAIDs may cause a dose-dependent decrease in prostaglandin formation and sudden renal failure. The importance of prostaglandin in maintaining renal blood flow should be considered when using the drug in patients with impaired cardiac, renal or hepatic function, in patients receiving diuretics or in patients after surgery, as well as in elderly patients.
Caution should be exercised when using the drug in patients with mild or moderate impairment of liver and kidney function, as well as in patients with other conditions predisposing to fluid retention in the body. In these patients, the use of NSAIDs can lead to impaired renal function and fluid retention. Caution should also be exercised when using Airtal in patients taking diuretics or in individuals at increased risk of hypovolemia. A minimum effective dose and regular medical monitoring of renal function are required. Renal reactions usually resolve after discontinuation of aceclofenac.
Aceclofenac should be discontinued if changes in liver function tests persist or worsen, clinical signs or symptoms of liver disease develop, or other manifestations (eosinophilia, rash) occur. Hepatitis can develop without prodromal symptoms.
The use of NSAIDs in patients with hepatic porphyria may precipitate an attack.
Allergic and skin reactions
Like other NSAIDs, the drug can cause allergic reactions, including anaphylactic/anaphylactoid reactions, even when taken for the first time. Severe skin reactions (which can sometimes be fatal), including exfoliative dermatitis, Stevens-Johnson syndrome and toxic epidermal necrolysis, have been very rare after taking NSAIDs. The highest risk of these reactions occurring in patients is observed at the beginning of using the drug, and the development of these adverse reactions is observed during the first month of using the drug. If skin rash, lesions on the oral mucosa, or other signs of hypersensitivity occur, discontinue use of aceclofenac.
In special cases, complications may occur with chickenpox:
- serious skin and soft tissue infections. At present, the role of NSAIDs in worsening the course of these infections cannot be ruled out. Therefore, the use of Airtal for chickenpox should be avoided.
Hematological disorders
Aceclofenac may cause reversible inhibition of platelet aggregation.
Respiratory system disorders
The drug should be used with caution in patients with bronchial asthma currently or in history, because taking NSAIDs may trigger the development of sudden bronchospasm in such patients.
Elderly patients
Caution should be exercised when using the drug in elderly patients, because they are more likely to experience adverse reactions (especially bleeding and gastrointestinal perforation) when taking NSAIDs. Complications can be fatal. In addition, older patients are more likely to suffer from kidney, liver or cardiovascular diseases.
Long-term use
All patients receiving long-term treatment with NSAIDs should be closely monitored (eg, complete blood count, monitoring of liver and kidney function).
Impact on the ability to drive vehicles and operate machinery
Patients who have experienced symptoms such as weakness, dizziness, vertigo, nausea or other central nervous system symptoms while using NSAIDs should refrain from driving vehicles or operating dangerous machinery.
How to take it
The tablets are taken orally and must be taken with meals. Otherwise, stomach problems will arise. Drink with plenty of water. For severe pain, take it once in the morning and once in the evening. If the pain is periodic, take it once.
If you have kidney failure, you should not take this drug without a doctor's supervision. The doctor must assess the patient's condition, the results of glomerular filtration tests and calculate the correct dose. Otherwise, serious complications are possible.
The powder is diluted with water in the indicated dosage and taken orally twice a day. Sometimes patients prefer the drug in liquid form.
The ointment is rubbed into the affected areas of the body three times a day. Squeeze out the cream the size of a pea (two grams).
In case of overdose, increased side effects occur. You need to stop taking it, drink activated charcoal and call for medical help.
How to replace the drug Airtal
The group of non-steroidal anti-inflammatory analgesics includes a whole list of drugs, including cheaper ones and those that have fewer contraindications in their description.
Paracetamol and ibuprofen are considered the safest. These substances, being part of many multicomponent drugs, relieve pain, normalize body temperature and reduce the intensity of the inflammatory process. Both paracetamol and ibuprofen are approved for use in children. The dosage form in the form of syrup allows use by children over 3 months. Ibuprofen is better for toothache and joint pain.
Paracetamol is aimed at combating headaches and muscle aches. For severe joint pain, Aertan can be replaced with Diclofenac. This active substance is sold in pharmacies. Under the same name it is found not only in the form of tablets, but also in the form of ointments, patches and ampoules for intramuscular administration. The extended-release formula of the tablets allows you to take one dose, which will relieve severe pain for 24 hours.
Drug combination
If you take the drug together with blood pressure medications and diuretics, the therapeutic effect of these medications may be weakened. If you have diabetes mellitus of the first degree, you should carefully monitor your blood sugar levels while taking the drug. Do not take simultaneously with aspirin, oral contraceptives, medications containing lithium and potassium, cyclosporins, blood thinners.
You should drive carefully while taking Aethral. Possible decrease in concentration.
