Compound
Syrup composition: 10 ml of syrup contains 100 mg of guaifenesin , 4 mg of bromhexine hydrochloride , 2 mg of salbutamol sulfate , 1 mg of menthol .
Excipients:
- purified water;
- sucrose;
- sunset yellow dye;
- black currant flavor;
- pineapple flavor;
- glycerol;
- sorbitol;
- sodium benzoate;
- propylene glycol;
- citric acid monohydrate.
Composition of the medicine in tablets : one tablet contains 100 mg of guaifenesin , 8 mg of bromhexine hydrochloride , 2 mg of salbutamol sulfate .
One tablet also contains the following excipients:
- purified talc;
- corn starch;
- methyl parahydroxybenzoate;
- colloidal silicon dioxide;
- propyl parahydroxybenzoate;
- Magnesium stearate.
Indications for use of Ascoril
In order for the drug to have the correct effect, you need to know exactly what exactly these tablets or syrup are for and what kind of cough they help with. The medicine is taken:
- with dry cough;
- for whooping cough ;
- for tuberculosis ;
- for bronchial asthma ;
- with tracheobronchitis .
Contraindications
First of all, this drug is contraindicated for people with hypersensitivity to the components of the drug.
Also, the following diseases are contraindications to taking this drug:
- heart disease;
- diabetes;
- ulcer;
- glaucoma;
- liver, kidney failure
The drug is also contraindicated during pregnancy and breastfeeding.
Side effects
Rarely (usually with an overdose) the following symptoms may occur:
- headache;
- nausea;
- tremor;
- sleep disturbance;
- dizziness;
- increased excitability;
- nervousness;
- drowsiness.
Side effects
During treatment, children may experience adverse reactions:
- Allergy;
- Sleep disturbance;
- Headache;
- Constant fatigue;
- Tremor of the limbs;
- Increased excitability;
- Dysbacteriosis;
- Nausea;
- Bloating and colic;
- Decreased blood pressure.
Sometimes the use of Ascoril gives a very strange symptom in the form of pink urine. This reaction is considered normal and does not require discontinuation of the drug. Other signs give reason to replace the product with an analogue.
Instructions for use of Ascoril (Method and dosage)
Instructions for use of Ascoril syrup
This expectorant should be taken by children under 6 years old, 5 ml 3 times a day, from 6 to 12 years old - 5-10 ml per day, from 12 years old - 10 ml 3 times a day.
Instructions for use of Ascoril tablets
Children under 6 years of age are not recommended to take this medicine.
From 6 to 12 years – ½ tablet 3 times a day.
From 12 years – 1 tablet 3 times a day.
How to take Ascoril - before or after meals?
Following the instructions for use, but regardless of food intake.
General characteristics of Ascoril syrup
A transparent liquid with a pronounced orange tint and aroma are the key “identifying marks” of this medicine. The taste is also specific, but even in small children it does not cause rejection, therefore it is mainly used without dilution in water. According to doctors, a 100 ml bottle is more than enough for a full therapeutic course. Considering its cost (300-400 rubles), this is not the most expensive cough medicine.
The effect of taking it, especially in children, is observed after half an hour, but its duration is no more than 8 hours, so the use should be repeated.
- Doctors call the main indications for the use of Ascoril syrup almost any disease of the bronchopulmonary system, accompanied by a cough in which the discharge of sputum is difficult (or not observed at all). The nature of the disease (infectious, bacterial, etc.) is not taken into account - it makes sense to take the drug even when coughing, which is caused by exhaling construction dust.
However, this drug is not advisable to use during pregnancy, because salbutamol can have an effect on the tone of the uterus, and nursing mothers need to wean the baby from the breast during treatment and can continue feeding only 2 days after the course is completed. Additionally, doctors advise hypertensive patients and people with heart problems to exercise caution. Diabetics, patients with thyretoxicosis, glaucoma and damage to the gastric mucosa should avoid this medicine.
medicine
Ascoril for children is aimed at liquefying and expectorating mucus from the bronchi. The drug is produced in the form of syrup - an orange, pleasant-tasting, slightly viscous liquid, and tablets. Before use, read the instructions to understand at what age it should be given to children. Also pay attention to what kind of cough and for how many days you can take the remedy.
Analogues of Ascoril
Level 4 ATX code matches:
Mukolik
Cashnol
Abrol
Anise oil
Ambrosan
Bronchophyte
Pulmolor
Pine buds
Pertussin
Bronchosan
Bronchorus
Gedelix
ACC 100
ACC 200
ACC Long
Mixture for inhalation
ACC
Mukolwan
Lazolvan
Herbion ivy syrup
Many people are often interested in the question of what to replace this or that medicine with. Ascoril has several similar drugs, which are worth talking about in more detail. It should be noted that, although similar, the drugs have some differences in composition. The price of Ascoril analogues also varies greatly.
Along with Ascoril, doctors often prescribe drugs: Lazolvan, Ambrobene, ACC, Erespal .
Which is better: Ascoril or Lazolvan?
These drugs differ in that they have different active ingredients. Moreover, the first is an expectorant drug, while Lazolvan is a stimulant of the motor function of the respiratory tract. These medications are prescribed for the same diseases. Ascoril and Lazolvan can be taken at the same time, but it is better to stick to one drug.
It is also worth clarifying what cough these medications are for. Being an expectorant, Ascoril treats dry cough , while Lazolvan can be used at any stage of the disease.
Which is better: Ascoril or Ambrobene?
These drugs have almost the same effect on the human body. They are both expectorants. The difference can only be found in how much this or that drug costs (the price of Ascoril is significantly higher than the cost of its analogue).
Which is better: Ascoril or ACC?
Both drugs have an expectorant, mucolytic effect. However, their composition is different. Differences can also be found in manufacturer and price. Thus, the price for an expectorant is higher than for its analogue.
Which is better: Askoril or Erespal?
Another analogue of Ascoril syrup and tablets is the medicine Erespal. Both medications have a similar composition and effect, but the price of Erespal is much higher.
All analogues of Ascoril have a similar composition and the same effect, therefore, if a doctor has prescribed one of these medications, but for some reason the drug is not suitable, you can decide for yourself what to replace it with.
Ascoril expectorant syrup 200ml fl
Pharmacological group:
Expectorants.
Pharmacological properties:
Combined expectorant.
Pharmacodynamics:
The combined drug has a bronchodilator, expectorant and mucolytic effect.
Salbutamol is a bronchodilator that stimulates beta2-adrenergic receptors of the bronchi, blood vessels and myometrium. Prevents or eliminates bronchospasm, reduces resistance in the respiratory tract, increases the vital capacity of the lungs. Causes dilatation of the coronary arteries, does not reduce blood pressure.
Bromhexine is a mucolytic agent. Has an expectorant effect, improves sputum discharge.
Guaifenesin is a mucolytic agent that reduces the surface tension of the structures of the bronchopulmonary apparatus; stimulates secretory cells of the bronchial mucosa that produce neutral polysaccharides, depolymerizes acidic mucopolysaccharides, reduces the viscosity of sputum, facilitates the removal of sputum and promotes the transition of a non-productive cough to a productive one.
Pharmacokinetics:
Salbutamol: when taken orally, absorption is high. Eating reduces the rate of absorption but does not affect bioavailability. Communication with plasma proteins - 10%. Penetrates through the placenta.
Subjected to first-pass metabolism in the liver and in the intestinal wall, it is inactivated by phenolsulfotransferase to 4-o-sulfate ester. The half-life (T1/2) is 3.8-6 hours. It is excreted by the kidneys (69-90%), mainly in the form of an inactive phenol sulfate metabolite (60%) within 72 hours and with bile (4%). The bioavailability of orally administered salbutamol is about 50%.
Bromhexine: When taken orally, it is almost completely (99%) absorbed from the gastrointestinal tract (GIT) within 30 minutes. Bioavailability is low (the effect of primary “passage” through the liver). Penetrates through the placental and blood-brain barriers. In the liver it undergoes demethylation and oxidation, metabolized to the pharmacologically active ambroxol. T1/2 -15 hours (due to slow reverse diffusion from tissues). Excreted by the kidneys. In chronic renal failure, the excretion of metabolites is impaired. May accumulate with repeated use.
Guaifenesin: absorption from the gastrointestinal tract is rapid (25-30 minutes after oral administration). T1/2 - 1 hour. Penetrates tissues containing acidic mucopolysaccharides.
Approximately 60% of the administered drug is metabolized in the liver. It is excreted by the lungs (with sputum) and the kidneys, both unchanged and in the form of inactive metabolites.
Ascoril for children
Many parents ask the question: “For what cough do they give this or that medicine?” As for Ascoril, doctors prescribe it for dry coughs in order to speed up the treatment process.
Also, many people are concerned about whether to take medicine before or after meals. It can be taken regardless of meals.
In general, many recommend giving both tablets and Ascoril syrup to children; reviews of this drug are very positive. Many parents praise this medicine in comparison with other analogues.
Instructions for use for children are as follows:
Ascoril cough syrup:
- up to 6 years, 5 ml 3 times a day;
- from 6 to 12 years – 5-10 ml per day;
- from 12 years old – 10 ml 3 times a day.
Cough tablets:
Children under 6 years of age are not recommended to take this medicine.
- from 6 to 12 years – ½ tablet 3 times a day;
- from 12 years old – 1 tablet 3 times a day.
What cough does Ascoril help with?
This drug belongs to the category of bronchodilators, i.e. drugs that help relieve spasm in the bronchi due to their expansion, but do not affect its root cause. Thus, Ascoril is a symptomatic remedy that has an auxiliary function, and cannot be the basis of a therapeutic regimen, because does not affect the source of the disease.
Ascoril cough syrup contains:
- Bromhexine is a mucolytic (or secretolytic), i.e. a substance that changes the composition of mucus accumulating in the bronchi and also helps improve expectoration. To a very small extent it has an antitussive effect. Combines well with bronchodilators. It is used for almost all diseases of the bronchopulmonary system.
- Guaifenesin is a substance that raises questions among most people, because... Among its properties, the leading one is anti-anxiety. It is mainly used to treat the nervous system and also to relieve headaches. However, in a certain dosage, it can also affect the viscosity of sputum, diluting it, which is the reason for the appearance of guaifenesin in drugs aimed at treating cough. The origin is completely natural.
- Salbutamol - this substance is responsible for the same bronchodilator effect that Ascoril has, and is actively used in drugs that are prescribed for the treatment of asthma, since it very quickly stops its manifestations. It also activates the removal of sputum, therefore it is also effective for chronic bronchitis.
- Menthol is a substance of natural origin that has a mild anesthetic effect. It is a weak antiseptic. Directly in this syrup it is used to enhance the bronchodilator effect (since it relieves any spasms well) and to alleviate the condition of a severe cough by soothing the irritated mucous membrane.
Thus, Ascoril is a combined drug: in addition to the already indicated property of relieving bronchospasm, it can also help in removing mucus from the lungs and reducing its viscosity. If you are interested in what kind of cough Ascoril syrup can be prescribed for, then experts assure you that there is no difference: the remedy is equally effective for both dry and wet coughs.
In pediatrics, this drug is valued for its mild effect on the child’s body and the absence of a long list of side effects. The partially natural composition helps minimize unwanted reactions, and the convenient form factor (liquid) makes the syrup enjoyable for the baby to use. However, as for the dosage, it is still advisable to entrust its calculation to a doctor, especially if you are planning to treat a cough in an infant or a child with a very sensitive body. For babies under one year of age, this medicine is prescribed by a doctor, so the dosage is not indicated in the instructions for them.
For the rest, the picture is as follows:
- Children one year old and older can drink up to 15 ml of Ascoril syrup per day, but it is advisable to divide this volume into 3 times rather than give it in one portion.
- For a child over 6 years old, you can increase the dose to 30 ml (volume per day), also dividing it into 3 times, but if the body is highly sensitive, start with the same 5 ml per dose.
- Schoolchildren aged 12 years and above are given 10 ml, since smaller doses do not have an effect. It is also advisable not to drink more than 30 ml per day. However, in case of severe illnesses, the doctor may recommend increasing the single dosage to 20 ml, and the daily dosage, respectively, to 60 ml.
The course of treatment with Ascoril syrup is mainly 5 days, and a maximum of a week. This is enough to relieve symptoms and remove phlegm, but if you do not get the desired effect within the specified period, you should not expect any further positive dynamics.
- Ascoril is taken after meals so as not to irritate the stomach. You can only drink clean water.
The only warning that doctors give to all mucolytics is not to combine them with codeine drugs, as well as expectorant reaction blockers: i.e. You are either trying to get rid of phlegm or you want to stop coughing attacks. In addition, you should not take Ascoril at the same time as antibiotics, because the latter will accumulate.
Reviews for Ascoril
In general, doctors' reviews of Ascoril tablets are positive, but some experts are skeptical about it because of the manufacturer. Reviews about the syrup are no different.
Patients say that the drug helps quickly and without complaints. Many people recommend giving this particular syrup to children; reviews of the tablets among patients are the same. The medicine also attracts patients because of its affordable price.
However, some patients complain of severe side effects ( tremor , dizziness , rapid heartbeat , increased blood pressure).
Interaction
Other beta2-adrenergic agonists and theophylline enhance the effect of salbutamol and increase the likelihood of side effects.
Ascoril expectorant is not prescribed simultaneously with drugs containing codeine and other antitussives, because this makes it difficult to clear liquefied sputum.
Bromhexine, which is part of the drug, promotes the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline) into the lung tissue.
It is not recommended to use the drug simultaneously with non-selective beta-adrenergic blockers such as propranolol.
Salbutamol, which is part of the drug, is not recommended for patients receiving MAO inhibitors.
Diuretics and corticosteroids enhance the hypokalemic effect of salbutamol.
It is not recommended to take alkaline drinks simultaneously with the drug Ascoril expectorant.
Askoril price, where to buy
The price varies depending on the country, and more specifically, the city.
The cost of the drug in Russia starts from 180 rubles.
The price of Ascoril syrup in Ukraine ranges from 130 to 230 UAH. In Kharkov, this medicine can be bought for 140 UAH. You can find out exactly how much the syrup costs at your nearest pharmacy.
The price of Ascoril tablets is approximately 117 – 280 UAH, depending on the pack. In Odessa, Ascoril tablets can be purchased for approximately 120 to 230 UAH.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
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