How to take Reduxin 15 mg to lose weight: instructions for use

What is Reduxin

Reduxin is a combined drug used in the treatment of certain degrees of obesity, which affects receptors and certain areas of the central nervous system and brain, causing a feeling of satiety. As a result, there is a decrease in food cravings.

The active ingredients also reduce blood glucose levels, which helps suppress appetite, reducing the risk of overeating.

Composition of Reduxin

There are several varieties of Reduxin: blue capsules have a low concentration of the active substance, blue capsules have a high concentration. Their composition:

Potential buyers should be aware that a doctor's prescription is required to purchase the drug.

Release form

The capsules are packaged in blisters of 30 pieces - these tablets are just enough for one month of treatment. They are also divided according to the concentration of the active substance - 10 or 15 mg. An important point: the manufacturer produces the product only in cardboard boxes; capsules in plastic jars are fake! The price of the drug varies from 900-1000 rubles to 3-4 thousand, it all depends on the number of capsules in the package: 10, 20 or 30.

pharmachologic effect

Sibutramine is the main active ingredient in weight loss capsules. Due to this, the drug has an effect on the central nervous system through primary and secondary amines or metabolites that reuptake the hormones serotonin, norepinephrine, and dopamine. This increases the activity of neurotransmitters located in synapses, which are responsible for the feeling of fullness, satiety, and a decrease in the need for food.

Microcrystalline cellulose acts as an enterosorbent - a substance that, when it enters the stomach or intestines, absorbs various toxic wastes and poisons, and then exits through the organs of the excretory system through defecation.

Composition of Reduxin

According to reviews from those losing weight, when taking the drug they feel high activity, mild euphoria and at the same time do not feel any feeling of hunger. All this is explained by the fact that Reduxin contains the following components:

1. Sibutramine is the main active ingredient. Sibutramine is ideal for weight loss, because its action is aimed at reducing appetite, reducing hunger, and in general, so that a person prone to overeating consumes fewer calories. In addition to its effect on the satiety center in the brain, the substance is distinguished by its effect on adrenergic receptors, due to which fat cells are broken down. Next, fatty acids are converted into energy, and the resulting water and glycerol are excreted from the body.
2. Microcrystalline cellulose is a substance that, when it enters the stomach, swells greatly, due to which a person eats a smaller portion. When cellulose swells, it absorbs a huge amount of water and additionally “grabs” harmful substances, but this causes not only a lack of appetite, but also severe thirst.

How to take Reduxin correctly to lose weight

Regardless of the concentration of the active ingredient, Reduxin is prescribed by a doctor and taken one capsule once a day. But you should know that the maximum allowed amount is 15 mg per day, and the general course of treatment is 3 months. To date, no serious cases of overdose have been identified, but judging by the reviews of patients on thematic forums, taking drugs at the prescribed rate often causes side effects!

When is it better to use: morning or evening? There are no clear recommendations on this matter, so it is better for everyone to choose the most convenient time for themselves with the help of a doctor. The capsule should be taken with a sufficient amount of water. It is advisable not to eat for at least 30-40 minutes after taking it.

Instructions for use

Reduxin should be taken only in the dosage prescribed by your doctor. Usually, Reduxin is started with a small dose of about 5-10 mg.

Pros and cons of use

The positive effect is explained by the effect on the body of the active substance – sibutramine, which:

• Helps reduce hunger, suppress appetite, reduce cravings for “forbidden” foods (fatty, flour, smoked, highly salty and sweet).
• Improves metabolism.
• Reduces weight, reduces waist and hips.
• Removes impurities, toxins, excess liquid.
• Reduces the amount of fat, prevents the formation of deposits around internal organs.

Does Reduxin really help you lose weight? Despite the fact that the active substance itself is effective, all the positive aspects of taking capsules are overshadowed by the huge lists of contraindications and side effects discussed below.

Course duration

The duration of the course is prescribed by the doctor, usually it is three months. If, after four weeks from the start of treatment, weight loss to at least two kilograms has not been achieved, then the daily dosage is usually increased to 15 mg. The drug should also not be resumed if the weight has returned after discontinuation of the capsules.

Between three-month courses it is necessary to take a break of at least 14 days, and the total duration of use should not exceed one year, since there is no laboratory research data confirming or refuting the safety and effectiveness of the drug in this case.

Indications for use

A course of Reduxin is prescribed by a doctor based on an examination of the patient, collecting an anamnesis and studying tests. Capsules can be recommended by a specialist in the following cases:

in case of alimentary or primary obesity associated with diseases of the metabolism or endocrine system, hormonal imbalances, provided that the patient’s body mass index exceeds 30 (the norm for a healthy person is on average 20-26);

with the alimentary type of obesity, if the body mass index exceeds 27 and there are concomitant diseases caused by excess body weight - type 2 diabetes mellitus, lipid metabolism disorders, etc.

Reduxin is often recommended by a doctor if obesity is pathological and caused by metabolic disorders. In this case, standard weight loss methods do not produce results - but such cases are extremely rare. Usually the reasons why weight has stopped or does not decrease at all are quite prosaic - incorrect calorie counting, constant overeating and breakdowns, lack of physical activity. And in this case, no miracle drugs or capsules will help; the main weapon in the fight against excess weight should be proper nutrition in combination with psychotherapy of eating habits. You need to understand what led to the gain of extra pounds, learn to deal with difficulties, and love your own body.

About the drug Reduxin

Lactic acidosis

Lactic acidosis is a rare but serious (high mortality unless promptly treated) complication that may occur due to accumulation of metformin. Cases of lactic acidosis when taking metformin occurred mainly in diabetic patients with severe renal failure.

Other associated risk factors should be taken into account, such as decompensated diabetes mellitus, ketosis, prolonged fasting, alcoholism, liver failure and any condition associated with severe hypoxia. This may help reduce the incidence of lactic acidosis.

The risk of developing lactic acidosis should be taken into account when nonspecific signs appear, such as muscle cramps accompanied by dyspeptic symptoms, abdominal pain and severe asthenia. Lactic acidosis is characterized by acidotic shortness of breath, abdominal pain and hypothermia followed by coma. Diagnostic laboratory parameters are a decrease in blood pH (less than 7.25), lactate content in the blood plasma over 5 mmol/l, increased anion gap and lactate/pyruvate ratio. If metabolic acidosis is suspected, stop taking the drug and consult a doctor immediately.

Surgical operations

The use of the drug Reduxin® Forte should be discontinued 48 hours before planned surgical operations and can be continued no earlier than 48 hours after, provided that during the examination, renal function was found to be normal.

Kidney function

Since metformin is excreted by the kidneys, before starting to take the drug Reduxin® Forte and regularly thereafter, it is necessary to determine CC: at least once a year in patients with normal renal function, and 2-4 times a year in elderly patients, as well as in patients with CC at the lower limit of normal.

Particular caution should be exercised in case of possible impairment of renal function in elderly patients, with simultaneous use of antihypertensive drugs, diuretics or non-steroidal anti-inflammatory drugs.

Patients are advised to continue to follow a diet with even carbohydrate intake throughout the day. Overweight patients are recommended to continue to follow a hypocaloric diet (but not less than 1000 kcal/day).

It is recommended that routine laboratory tests be performed regularly to monitor diabetes mellitus.

It is recommended to exercise caution when using Reduxin® Forte in combination with insulin or other hypoglycemic agents (including sulfonylurea derivatives, repaglinide).

Treatment with Reduxin® Forte should be carried out as part of complex therapy for weight loss under the supervision of a physician with practical experience in the treatment of obesity. Complex therapy includes both changing diet and lifestyle, as well as increasing physical activity. An important component of therapy is to create the prerequisites for persistent changes in eating behavior and lifestyle, which are necessary to maintain the achieved weight loss even after drug therapy is discontinued. As part of therapy with Reduxin® Forte, patients need to change their lifestyle and habits in such a way as to ensure that the achieved weight loss is maintained after completion of treatment. Patients should be clear that failure to comply with these requirements will lead to repeated weight gain and repeated visits to their doctor.

In patients taking the drug Reduxin® Forte, it is necessary to measure blood pressure and heart rate. During the first 3 months of treatment, these parameters should be monitored every 2 weeks and then monthly. If during two consecutive visits an increase in resting heart rate ≥10 beats per minute or systolic/diastolic pressure ≥10 mmHg is detected. Art., it is necessary to stop treatment. In patients with arterial hypertension whose blood pressure is above 145/90 mm Hg during antihypertensive therapy. Art., this control should be carried out especially carefully and, if necessary, at shorter intervals. In patients whose blood pressure exceeded 145/90 mmHg twice during repeated measurements. Art., treatment with Reduxin® Forte should be suspended (see section “Side effects”, subsections “Heart disorders”, “Vascular disorders”).

In patients with sleep apnea, blood pressure must be monitored especially carefully.

The simultaneous administration of drugs that increase the QT interval requires special attention. These drugs include H1-histamine receptor blockers (astemizole, terfenadine); antiarrhythmic drugs that increase the QT interval (amiodarone, quinidine, flecainide, mexiletine, propafenone, sotalol); gastrointestinal motility stimulator cisapride; pimozide, sertindole and tricyclic antidepressants. This also applies to conditions that can lead to an increase in the QT interval, such as hypokalemia and hypomagnesemia (see section “Interaction with other drugs”).

The interval between taking MAO inhibitors (including furazolidone, procarbazine, selegiline) and Reduxin® Forte should be at least 2 weeks.

Although a connection has not been established between taking sibutramine and the development of primary pulmonary hypertension, however, given the well-known risk of drugs in this group, with regular medical monitoring it is necessary to pay special attention to symptoms such as progressive dyspnea (breathing difficulty), chest pain and swelling in the legs .

If you miss a dose of Reduxin® Forte, you should not take a double dose of the drug at the next dose; it is recommended to continue taking the drug according to the prescribed regimen.

When taking sibutramine and other serotonin reuptake inhibitors together, there is an increased risk of bleeding. In patients predisposed to bleeding or taking drugs that affect hemostasis or platelet function, sibutramine should be used with caution.

Although there is no clinical evidence of addiction to sibutramine, the patient's history of drug dependence should be assessed and attention should be paid to possible signs of drug abuse.

Contraindications

List of contraindications for the use of Reduxin:

• individual intolerance, sensitivity or allergy to the components included in the composition - sibutramine, microcrystalline cellulose;
• the presence of organic causes of excess weight - congenital or acquired diseases that cause metabolic disorders, changes in hormonal levels;
• eating disorders caused by psychological factors - anorexia or bulimia;
• simultaneous use of MAO inhibitors - drugs used to treat alcoholism, depression and some other mental illnesses and disorders;
• use of drugs that affect the central nervous system (neuroleptics, antidepressants), as well as drugs to normalize sleep;
• benign prostatic hyperplasia;
• pheochromocytoma;
• schizophrenia, organic psychoses;
• adrenal tumor;
• excess production of thyroid hormones;
• glaucoma;
• diseases of the heart, congenital and acquired, blood vessels, veins;
• uncontrolled arterial hypertension;
• Gilles de la Tourette syndrome (generalized tics);
• disturbances in the functioning of the kidneys and liver;
• pregnancy, breastfeeding period;
• age under 18 and over 60.

Often, people do not even suspect that they have diseases, since many develop without pronounced symptoms, so it is strictly not recommended to use Reduxin without consulting a weight loss specialist.

Reduxin caps 15 mg x30

Trade name: Reduksin International name: Sibutramine+[Microcrystalline cellulose]& (Sibutramine+Cellulose microcrystallic) Pharmacological group: obesity treatment Pharmacological group according to ATC: A08AA. Drugs for the treatment of obesity with central action Pharmacological action: monoamine reuptake inhibitor, treatment for obesity Pharmacodynamics: Combined drug for the treatment of obesity, the effect of which is determined by its constituent components. Sibutramine is a prodrug and exerts its effect in vivo through metabolites (primary and secondary amines) that inhibit the reuptake of monoamines (mainly serotonin and norepinephrine). An increase in the content of neurotransmitters in synapses increases the activity of central serotonin 5-HT receptors and adrenergic receptors, which increases the feeling of satiety and reduces the need for food, as well as an increase in thermal production. By indirectly activating beta 3-adrenergic receptors, sibutramine acts on brown adipose tissue. A decrease in body weight is accompanied by an increase in the concentration of HDL in the blood serum and a decrease in the amount of triglycerides, total cholesterol, LDL, and uric acid. Sibutramine and its metabolites do not affect the release of monoamines, do not inhibit MAO, and do not have an affinity for a large number of neurotransmitter receptors, including serotonin (5-HT1, 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C), adrenergic receptors (beta 1, beta 2, beta 3, alpha 1, alpha 2), dopamine (D1, D2), muscarinic, histamine (H1), benzodiazepine and NMDA receptors. Microcrystalline cellulose is an enterosorbent, has sorption properties and a nonspecific detoxification effect. Binds and removes from the body various microorganisms, their metabolic products, toxins of exogenous and endogenous nature, allergens, xenobiotics, as well as an excess of certain metabolic products and metabolites responsible for the development of endogenous toxicosis. Pharmacokinetics: Absorption, distribution, metabolism After taking the drug orally, sibutramine is quickly absorbed from the gastrointestinal tract, no less than 77%. It is subject to the effect of the first passage through the liver and is biotransformed with the participation of the CYP3A4 isoenzyme with the formation of two active metabolites (mono- and didesmethylsibutramine). After taking a single dose of 15 mg, the Cmax of monodesmethylsibutramine is 4 ng/ml (3.2-4.8 ng/ml), didesmethylsibutramine - 6.4 ng/ml (5.6-7.2 ng/ml). The Cmax of sibutramine is achieved after 1.2 hours, of active metabolites - after 3-4 hours. Taking along with food reduces the Cmax of metabolites by 30% and increases the time to reach it by 3 hours, without changing the AUC. Quickly distributed into tissue. The binding of sibutramine to plasma proteins is 97%, and mono- and didesmethylsibutramine is 94%. Css of active metabolites in the blood is achieved within 4 days after the start of treatment and is approximately 2 times higher than the plasma level after taking a single dose. Elimination T1/2 of sibutramine - 1.1 hours, monodesmethylsibutramine - 14 hours, didesmethylsibutramine - 16 hours. Active metabolites undergo hydroxylation and conjugation to form inactive metabolites, which are excreted primarily by the kidneys. Indications for use: To reduce body weight in the following conditions: alimentary obesity with a body mass index (BMI) of 30 kg/m2 or more, alimentary obesity with a BMI of 27 kg/m2 or more in combination with other risk factors caused by excess body weight ( diabetes mellitus type 2 /non-insulin dependent/ or dyslipoproteinemia). Contraindications: the presence of organic causes of obesity (for example, hypothyroidism), serious eating disorders (anorexia nervosa or bulimia nervosa), mental illness, Gilles de la Tourette syndrome (generalized tics), concomitant use of MAO inhibitors (for example, phentermine, fenfluramine, dexfenfluramine, ethylamphetamine, ephedrine) or their use within 2 weeks before prescribing Reduxin, the use of other drugs acting on the central nervous system (for example, antidepressants, antipsychotics), drugs prescribed for sleep disorders containing tryptophan, as well as other centrally acting drugs for weight loss body, coronary artery disease, decompensated chronic heart failure, congenital heart defects, occlusive diseases of peripheral arteries, tachycardia, arrhythmias, cerebrovascular diseases (stroke, transient cerebrovascular accident), uncontrolled arterial hypertension (BP above 145/90 mm Hg), thyrotoxicosis, severe liver dysfunction, severe kidney dysfunction, benign prostatic hyperplasia, pheochromocytoma, closed-angle glaucoma, established drug, drug or alcohol addiction, pregnancy, lactation (breastfeeding), children and adolescents under 18 years of age, elderly over 65 years of age, known hypersensitivity to sibutramine or other components of the drug. With caution: The drug should be prescribed with caution in the following conditions: a history of arrhythmias, chronic circulatory failure, coronary artery disease (including a history), cholelithiasis, arterial hypertension (controlled and in history), neurological disorders, including mental retardation development and convulsions (including a history), impaired liver and/or kidney function of mild to moderate severity, a history of motor and verbal tics. https://reduxin.ru/instruction/ Dosage regimen: Reduxin is prescribed orally 1 time/ The dose is set individually, depending on tolerability and clinical effectiveness. The recommended starting dose is 10 mg; in case of poor tolerance, a dose of 5 mg can be taken. Capsules should be taken in the morning, without chewing and with sufficient liquid. The drug can be taken on an empty stomach or combined with meals. If within 4 weeks from the start of treatment a reduction in body weight of 5% or more is not achieved, then the dose is increased to 15 mg. The duration of therapy with Reduxin should not exceed 3 months in patients who do not respond well to therapy (i.e. within 3 months of treatment it is not possible to reduce weight by 5% of initial body weight). Treatment should not be continued if, with further therapy (after achieving a reduction in body weight), the patient again gains 3 kg or more in body weight. The total duration of therapy should not exceed 2 years, since there are no data on efficacy and safety for a longer period of taking sibutramine. Therapy with Reduxin should be carried out by a doctor with practical experience in the treatment of obesity. Taking the drug should be combined with diet and exercise. Side effects: Side effects, depending on the effect on organs and organ systems, are presented in the following order (often - >10%, sometimes - 1-10%, rarely - from the central nervous system and peripheral nervous system: often - dry mouth, insomnia, sometimes - headache, dizziness, anxiety, paresthesia, as well as changes in taste, in isolated cases - back pain, depression, drowsiness, emotional lability, anxiety, irritability, nervousness, convulsions. In one patient with schizoaffective disorder, which is suspected existed before the start of treatment, after treatment acute psychosis developed. From the cardiovascular system: sometimes - tachycardia, palpitations, increased blood pressure, vasodilation. There is a moderate increase in blood pressure at rest by 1-3 mmHg and a moderate increase in pulse by 3-7 beats per minute. In some cases, more pronounced increases in blood pressure and heart rate cannot be excluded. Clinically significant changes in blood pressure and heart rate are recorded mainly at the beginning of treatment (in the first 4-8 weeks). From the digestive system: often - loss of appetite, constipation, sometimes - nausea, exacerbation of hemorrhoids. If you are prone to constipation in the first days, monitoring the evacuation function of the intestines is necessary. If constipation occurs, stop taking it and take a laxative. In isolated cases, abdominal pain, paradoxical increase in appetite, transient increase in the activity of liver enzymes. Dermatological reactions: sometimes - sweating, in isolated cases - itching, Henoch-Schönlein purpura (bleeding into the skin). From the body as a whole: in isolated cases the following undesirable clinically significant phenomena have been described: dysmenorrhea, edema, influenza-like syndrome, thirst, rhinitis, acute interstitial nephritis, bleeding, thrombocytopenia. Withdrawal reactions such as headache or increased appetite are rare. There is no evidence that withdrawal symptoms, withdrawal symptoms or mood disturbances occur after treatment. Most often, side effects occur at the beginning of treatment (in the first 4 weeks). Their severity and frequency weaken over time. Side effects are generally mild and reversible. Overdose: There are extremely limited data on overdose of sibutramine. Symptoms: increased severity of side effects. Specific signs of overdose are unknown. Treatment: taking activated charcoal, gastric lavage, symptomatic therapy, with increased blood pressure and tachycardia - prescribing beta-blockers. There is no specific antidote. It is necessary to carry out general measures: ensure free breathing, monitor the state of the cardiovascular system, and, if necessary, carry out supportive symptomatic therapy. The effectiveness of forced diuresis or hemodialysis has not been established. Interaction: Inhibitors of microsomal oxidation, incl. CYP3A4 inhibitors (including ketoconazole, erythromycin, cyclosporine) increase plasma concentrations of sibutramine metabolites with an increase in heart rate and a clinically insignificant increase in the QT interval. Rifampicin, macrolide antibiotics, phenytoin, carbamazepine, phenobarbital and dexamethasone can accelerate the metabolism of sibutramine. The simultaneous use of several drugs that increase the level of serotonin in the blood can lead to the development of a serious interaction. The so-called serotonin syndrome can develop in rare cases when Reduxin is used simultaneously with selective serotonin reuptake inhibitors (drugs for the treatment of depression), with certain drugs for the treatment of migraines (sumatriptan, dihydroergotamine), with potent analgesics (pentazocine, pethidine, fentanyl) or antitussives drugs (dextromethorphan). Sibutramine does not affect the effect of oral contraceptives. When sibutramine and ethanol were taken simultaneously, there was no increase in the negative effects of ethanol. However, alcohol consumption is absolutely not combined with the dietary measures recommended when taking sibutramine. Special instructions: Reduxin should be used only in cases where all non-drug measures for weight loss are ineffective - if the weight loss over 3 months is less than 5 kg. Treatment with Reduxin should be carried out as part of complex therapy for weight loss under the supervision of a physician with practical experience in the treatment of obesity. Complex therapy for obesity includes both changes in diet and lifestyle, as well as increased physical activity. An important component of therapy is the creation of prerequisites for permanent changes in eating habits and lifestyle, which are necessary to maintain the achieved weight loss even after drug therapy is discontinued. As part of therapy with Reduxin, patients need to change their lifestyle and habits in such a way as to ensure that the achieved weight loss is maintained after completion of treatment. Patients should be clear that failure to comply with these requirements will lead to repeated weight gain and repeated visits to their doctor. In patients taking Reduxin, it is necessary to measure blood pressure and heart rate. During the first 2 months of treatment, these parameters should be monitored every 2 weeks and then monthly. In patients with arterial hypertension (whose blood pressure levels are above 145/90 mmHg during antihypertensive therapy), this monitoring should be carried out especially carefully and, if necessary, at shorter intervals. In patients whose blood pressure exceeded 145/90 mmHg twice during repeated measurements. Art. treatment with Reduxin should be suspended. The simultaneous administration of drugs that increase the QT interval requires special attention. These drugs include histamine H1 receptor blockers (astemizole, terfenadine), antiarrhythmic drugs that increase the QT interval (amiodarone, quinidine, flecainide, mexiletine, propafenone, sotalol), gastrointestinal motility stimulants (cisapride, pimozide, sertindole and tricyclic antidepressants). Caution should be exercised when using the drug against conditions that are risk factors for increasing the QT interval (hypokalemia, hypomagnesemia). The interval between taking MAO inhibitors and Reduxin should be at least 2 weeks. The connection between taking Reduxin and the development of primary pulmonary hypertension has not been established, however, given the well-known risk of drugs in this group, with regular medical monitoring it is necessary to pay special attention to symptoms such as progressive dyspnea (breathing difficulty), chest pain and swelling in the legs. Effect on the ability to drive vehicles and operate machinery Taking the drug Reduxin may limit the patient’s ability to drive vehicles and operate machinery.

Manufacturer: Ozon LLC, Russia Registration certificate holder: Avista LLC, Russia Release forms: capsules 10 mg, 15 mg (polymer jars, cellular contour packaging) Composition: sibutramine hydrochloride monohydrate 10/15 mg, microcrystalline cellulose 158.5/153.5 mg Belonging to the lists : Potent Shelf life: 3 years Registration data: LS-002110 dated 04/23/2010 Registration certificate status: valid HS codes: 3004 90 190 9

Side effects

Taking the drug without a doctor's prescription can cause serious harm to the body and lead to side effects, which include:

• From the central nervous system: headaches, anxiety and irritability, dry mouth accompanied by loss or change of tastes, burning or tingling sensation in the extremities - paresthesia.
• From the cardiovascular system: increased blood pressure, increased heart rate (pulse), tachycardia.
• From the gastrointestinal tract: the appearance of constipation, nausea and heartburn after eating, loss of appetite.
• In isolated, individual cases, itching or rashes on the skin, cramps, pain in the abdomen and lower back may occur.

Most often, side effects occur in the first month of taking the drug. During this time, it is necessary to especially carefully monitor your well-being: measure your blood pressure and pulse, consume a sufficient amount of fiber and plant fibers to prevent constipation, and do not forget to drink water - at least 1.5-2 liters daily.

Reduxin®

Reduxin® should be used only in cases where all non-drug measures for weight loss are ineffective - if the weight loss over 3 months is less than 5 kg. Treatment with Reduxin® should be carried out as part of complex therapy for weight loss under the supervision of a physician with practical experience in the treatment of obesity. Complex therapy includes both changing diet and lifestyle, as well as increasing physical activity. An important component of therapy is to create the prerequisites for persistent changes in eating behavior and lifestyle, which are necessary to maintain the achieved weight loss even after drug therapy is discontinued. As part of therapy with Reduxin®, patients need to change their lifestyle and habits in such a way as to ensure that the achieved weight loss is maintained after completion of treatment.

Patients should be clear that failure to comply with these requirements will lead to repeated weight gain and repeated visits to their doctor. In patients taking Reduxin®, it is necessary to regularly measure blood pressure and heart rate. During the first 3 months of treatment, these parameters should be monitored every 2 weeks and then monthly. If during two consecutive visits an increase in resting heart rate ≥ 10 beats per minute or systolic/diastolic pressure ≥ 10 mmHg is detected, treatment should be discontinued. In patients with arterial hypertension whose blood pressure is above 145/90 mmHg during antihypertensive therapy, this monitoring should be carried out especially carefully and, if necessary, at shorter intervals. In patients whose blood pressure exceeded 145/90 mmHg twice during repeated measurements, treatment with Reduxin® should be discontinued (see section “Side Effects”).

In patients with sleep apnea, blood pressure must be monitored especially carefully.

The simultaneous administration of drugs that increase the QT interval requires special attention. These drugs include H1-histamine blockers (astemizole, terfenadine); antiarrhythmic drugs that increase the QT interval (amiodarone, quinidine, flecainide, mexiletine, propafenone, sotalol); gastrointestinal motility stimulator cisapride; pimozide, sertindole and tricyclic antidepressants. This also applies to conditions that can lead to an increase in the QT interval, such as hypokalemia and hypomagnesemia (see also section “Interaction with other drugs”).

The interval between taking MAO inhibitors (including furazolidone, procarbazine, selegiline) and Reduxin® should be at least 2 weeks.

Although no connection has been established between taking the drug Reduxin® and the development of primary pulmonary hypertension, however, given the well-known risk of drugs in this group, with regular medical monitoring it is necessary to pay special attention to symptoms such as progressive dyspnea (breathing difficulty), chest pain and swelling on foot.

If you miss a dose of the drug Reduxin®, you should not take a double dose of the drug at the next dose; it is recommended to continue taking the drug according to the prescribed regimen.

The duration of taking Reduxin® should not exceed 1 year.

When taking sibutramine and other serotonin reuptake inhibitors together, there is an increased risk of bleeding. In patients predisposed to bleeding or taking drugs that affect hemostasis or platelet function, sibutramine should be used with caution.

Although there is no clinical evidence of addiction to sibutramine, the patient's history of drug dependence should be assessed and attention should be paid to possible signs of drug abuse.

Reduxin's analogs

Reduxin has several analogues - drugs that are similar in pharmacological properties, but differ in price, active ingredients and their dosage. Let’s take a closer look at the most common ones, but don’t forget that analogues should also be prescribed by a doctor.

When choosing capsules, experts pay attention to the concentration of the active substance and try to choose an analogue that is similar in effect.

Instructions for use of Reduxin

The instructions for use are the same for each type of drug - one tablet daily. Let's take a closer look at the three main types of capsules for weight loss Reduxin.

How to take Reduxin 10 mg

10 mg is the standard dose for the drug Reduxin. It is prescribed from the very beginning, but adjusted as necessary, reduced or increased.

Reduxin 10 mg has the following similarities with other varieties:

• - identical pharmacological properties, indications for use, contraindications, side effects;
• - effectively reduce appetite, help in the fight against food addiction;
• - help normalize glucose levels and remove “bad” cholesterol.

It is impossible to unequivocally answer the question of which concentration is better: it all depends on individual indications.

How to take Reduxin 15 mg

Reduxin 15 mg is distinguished by a high, maximum possible concentration of active ingredients, which is used if smaller ones do not give the desired result.

But it should be understood that such a concentration can be fatal to the body:

• — since 2010, the use of sibutramine in the countries of the European Community has been suspended;
• - according to current legislation, since January 2004 in the Russian Federation sibutramine has been recognized as potent and hazardous to health;
• — the sale of sibutramine-containing drugs is permitted only in pharmacies with a special prescription, which is subject to special registration;
• — sibutramine is also included in the list of the World Anti-Doping Agency (2010), where it is classified as a substance prohibited during competitions.

Before you start taking any “diet pills,” you need to think about whether getting an ideal figure is worth the side effects? Moreover, modern weight loss specialists are ready to offer their patients individually developed methods that are completely safe for the body.

How to take Reduxin Light

Reduxin Light belongs to the category of biologically active additives - dietary supplements, so you can purchase capsules at any pharmacy, without special prescription from a specialist. They contain conjugated linoleic acid - the main active component, belonging to the group of essential amino acids that the body is not able to synthesize on its own, but receives from protein foods - meat, dairy products, beans.

• Stimulate the functioning of the immune system.
• They have a powerful antioxidant effect, rejuvenating the body.
• Improves metabolic processes.
• Slow down the processes of fat deposition in subcutaneous fat.
• Promotes muscle growth during intense strength training.
• Act as a measure to prevent cardiovascular diseases.

There will be no great harm or side effects from such a biological additive, but you shouldn’t expect huge benefits either. Reduxin Light acts as a vitamin-mineral complex, nothing more. It is better, again, to entrust the choice and prescription of this dietary supplement to a doctor.

Price of Reduxin 15 mg

The drug should be sold only in pharmacies. Even if the price of Reduxin 15 mg in some dubious online store of Chinese goods is too cheap, you should refuse this purchase, because for such a promotion you can “undermine” your health. How much does Reduxin cost in a pharmacy? Its cost is quite affordable: a plate of 30 capsules costs about 2,700 rubles on average. It is worth noting that the drug is available only with a doctor’s prescription, so if you decide that only pills will help you lose weight, be sure to visit a doctor.

You can also order Reduxin online: in Moscow and St. Petersburg, delivery is carried out quickly and at a minimal cost. Here are the approximate prices of the original medicine and the drug Reduxin Light in different cities:

Real reviews about reduxin for weight loss

Olga, 26 years old: After the birth of my second child, my weight began to rapidly gain until I reached 87 kg with a height of 165 cm. As a young mother, I could not find time for myself, prepare a menu according to a diet plan, go to training regularly - all this is not for me. And I wanted to lose weight. Having seen enough promising “before and after” photos, I ran to the pharmacists at the nearest pharmacy. They didn’t sell me the drug, but they offered it a lighter version - Light. I took exactly the course and paid almost five thousand for it. What's the result? No. Wasted time, that’s why I give Reduksin the lowest score, I won’t recommend him.

Oleg, 45 years old: All my life I had a tendency to be overweight, over time the extra pounds kept adding and adding. The result is the second stage of obesity, accompanied by type 2 diabetes. It was not easy to go through the rehabilitation course on my own; I was constantly drawn to products from the “strictly prohibited” list. On one of the thematic forums, I found an interesting discussion about Reduxin, where they praised its positive aspects, and most importantly - complete control over appetite! I got it and tried it. During the first month, I really didn’t want to eat, but this was due to strong side effects. I was shivering, severe tachycardia developed, and shortness of breath appeared. I had to stop taking the capsules. And the kilograms lost during the month of torment came back with interest.

Katerina, 56 years old: due to age-related changes, I became the unfortunate owner of several extra pounds, which brought with it problems with blood pressure and heart. Doctors were unanimous: it is necessary to get rid of unnecessary volumes, because they are the main cause of illnesses. Having decided to fight the problem quickly and decisively, I purchased Reduxin capsules. In the first weeks of treatment, there was a huge surge of strength - it was nervous excitement, I went outside to walk more and spend energy. In the evenings I couldn’t sleep for a long time. Tension, as if the brain would explode, sometimes there was anxiety. Over time, such symptoms began to scare me, I had to turn to specialists, who recommended stopping taking the drug in order to undergo a comprehensive clinical examination, restore the body, and the energy spent.

Expert opinion

The drug is very difficult. By the way, it has long been prohibited in enlightened Europe, and this is not a good argument against (in terms of life safety, we will not be equal to third world countries, where street dealers can give back drugs). A number of studies have proven the presence of serious risks when using Reduxin: its work can undermine not only the heart, but also the brain, and even deaths have been noted more than once...

Yes, Reduxin has many contraindications. Those that are known at the moment are listed in the instructions. But this, again, is information not for you, but for your doctor. In the world of medicine and drugs, it is not for you to decide what is possible and what is not. Unless you're suicidal, of course.

Well, as for its importance for losing weight - how can I tell you more precisely... losing weight and getting healthier are not the same thing. Diseases not only make you fat, they can also make you dry out. Do you need to lose pounds at any cost - or just get healthy and get back to normal? This is fundamentally a choice, and not the same thing. Just because you've lost weight doesn't mean you've become healthier. Very often it's just the opposite. So you don’t have to strive to lose weight, you have to strive for health!

You can look at the question from this point of view: natural, natural is always better than artificial, “chemicalized”. Won't you argue? Have you read about modern ecology and all that? Now just compare: what do you think is more natural, more reliable, more healing - a common human habit that a psychotherapist will form for you with simple conversations without any medications, or chemistry, which will artificially and unregulatedly suppress your appetite, affecting the delicate nerve centers in some way? then poisons with a list of side effects that is still unknown?

Reduxin contraindications

The manufacturer warns that it is prohibited to use this medicine if you are hypersensitive to the active ingredient sibutramine or other components, during pregnancy, while breastfeeding, if you are under 18 or over 65 years old. In addition, contraindications for Reduxin include:

• thyrotoxicosis;
• bulimia, anorexia;
• hypothyroidism (organic obesity);
• pheochromocytoma;
• mental illnesses;
• severe kidney and liver disorders;
• closed-angle glaucoma;
• Tourette's syndrome;
• diseases of blood vessels, heart.

Reduxin is highly not recommended to be combined with any drugs that are classified as MAO inhibitors, with sleeping pills containing tryptophan, with antipsychotics and other medications that affect the receptors of the human central nervous system. The drugs that are incompatible with Reduxin also include those used to treat obesity and those with which the patient fights mental pathologies.

• Beef carpaccio - recipes step by step with photos. How to cook beef carpaccio at home
• Bilirubin in the blood - normal table for children and adults. Causes of increased bilirubin in the blood and how to reduce it
• Richest man in the world 2017