Xeroform powder: instructions for use, analogues in pharmacies and reviews

Compound

Xeroform is a yellow powder with a weak specific odor.
The powder particles are small and do not have the correct crystalline structure (that is, the powder belongs to the category of amorphous substances). Being essentially the main salt of bismuth (Bismutum) - a chemical element of group V of the periodic system of D.I. Mendeleev. The bismuth tribromophenolate molecule is formed from successive bismuth oxide-hydroxide bonds with tribromophenol radicals at the ends.

In bismuth tribromophenolate used in the pharmaceutical industry, the bismuth oxide-hydroxide serial bonds must consist of three parts.

Xeroform is characterized by poor solubility in water, alcohols, ether and chloroform (it is even difficult to simply wet it with water); it is also slightly soluble in halogenated hydrocarbons and oils. The bismuth oxide content in it ranges from 50 to 55%.

However, some pharmaceutical sources indicate a slightly different percentage of bismuth oxide.

Thus, the 25th edition of the American Pharmacopoeia indicates that the content of bismuth oxide can vary from 44.6 to 54.5% (or from 40 to 49% bismuth), and in the 26th edition of the Martindal Extrapharmacopoeia it is noted that the percentage The bismuth oxide content is approximately 55.74%.

It should be noted that none of the given specifications corresponds to the molar ratio of bismuth to tribromophenolate, since the ideal structure according to the formulas given in the Pharmacopoeias is considered to be the ratio 3Bi/2Tribromophenol.

In cases where the ratio is lower, it will not meet the specification of the substance, but if it increases and approaches the values ​​of 4Bi/2Tribromophenol, the final product will take on a lighter yellow hue. If the ratio is even higher, the final product turns white.

How to use the drug for acne, wounds and bedsores

For the treatment of various skin diseases, applying the powder has its own characteristics.

Powder application features:

Xeroform method of administration and dosage

The powder is applied externally by applying it to the cleansed affected area of ​​the skin or mucous membranes 2-3 times a day. The duration of treatment depends on the type and activity of the pathological process and is determined by the doctor individually.

Possessing high hygroscopicity, the medication effectively adsorbs excess tissue fluid, sweat secretions, and blood. This action of Xeroform leads to stimulation of the process of evaporation and heat transfer. As a result of the activity of the drug, the lesion dries out and the area of ​​the skin defect decreases.

pharmachologic effect

During the treatment of shallow wounds and lesions of a small area, the drug has a rapid local effect. Powder for bedsores Xeroform has a balanced composition, does not dissolve in water, alcohol and oils, due to which it is widely used in medical practice for:

• drying wounds;
• vasoconstriction;
• relieving inflammatory processes of any location and degree of neglect;
• decreased sensitivity;
• preventing wound infection by pathogenic bacteria.

The active substance, bismuth tribromophenolate, “binds” the protein in cells with their membrane parts, which provides an excellent disinfecting effect of the drug.

Pharmacology

“Xeroform” disinfects the surface, destroying pathogenic bacteria and preventing their interaction with the membranes of the body’s cells. The powder also counteracts inflammatory processes.

The active component destroys proteins in the cell wall of bacteria and prevents their reproduction. It also dehydrates the surface, which is associated with a drying effect. In part, the medicine acts as an analgesic and hemostatic. This is due to the ability to protect the sensitivity of neurons from the effects of stimuli. The powder stimulates local blood circulation, making recovery processes faster.

The use of "Xeroform" leads to a decrease in the pathogenic activity of bacteria, drying of wounds, a decrease in the sensitivity of the skin and the cessation of inflammatory processes. Tissues heal faster due to regeneration processes.

Who should not use this medicine?

“Xeroform” instructions for use allow it to be used for the treatment of diseases in patients of any age category: from newborn babies to the elderly. The only contraindication in this case is individual intolerance.

It is worth noting that the use of the drug must be discontinued if side effects occur, including:

• Redness of the skin.
• Burning sensation.
• Various types of rashes.
• The appearance of edema.
• Severe itching in the area where the product was applied.

In general, Xeroform powder is easily tolerated by patients if the instructions are followed.

Features of the drug

Being a highly effective drug for external use in the presence of severe damage to the skin, Xeroform is of interest in the treatment of many types of lesions of the upper layer of the epidermis. The active substance eliminates within a short time the visible manifestations of the main lesion, stimulates the activation of metabolic processes in the skin, which makes it possible to quickly eliminate inflammation and accompanying pathological processes that worsen the appearance of the skin and reduce its protective properties.

The name of the drug in Latin is Xeroformium.

The dosage forms available for sale provide the opportunity to choose the type of product that will best cope with existing pathological manifestations, eliminating them and healing damaged skin. Xeroform can be used for application both to the skin and to mucous membranes (for example, eyes - a dosage form of eye ointment with a high content of Xeroform).

The main active part of any dosage form of the drug in question is the main bismuth salt, which has pronounced antiseptic properties, disinfecting the surface of the skin, stimulating its rapid recovery. The substance has a characteristic unobtrusive medicinal odor; in powder form it is practically insoluble in water, chloroform and alcohol.

Dosage forms

• powder, which is used only for external use in the presence of severe damage to the skin. The powder is sold in packages of 10 g; it is a homogeneous free-flowing product (powder) of a yellowish color;
• powder, which is easily and evenly applied to damaged areas of the skin due to its fine grinding and uniform consistency;
• eye ointment with a high content of xeroform (3%);
• ointment for external use based on xeroform (about 10%) and purified petroleum jelly (90%), which is perfectly absorbed into the skin, leaving no greasy marks on it and restoring the natural elasticity of the epidermis and the speed of its self-regeneration.

Xeroform is also included in and is the main active part of the Vishnevsky ointment, which is used in the treatment of external hemorrhoids, anal fissures, and cracking of the skin on the arms and legs.

Composition of Xeroform

The main active ingredient of any dosage form of this drug is bismuth oxide (Bismutum tribromphenylicum). It makes up about 55% of the total volume of the product. Xeroform in powder form is sold in 10 g packages.

Prices

The cost of this drug is quite affordable, which is important when purchasing a drug for the treatment of mechanical skin damage. The price may vary slightly depending on the seller’s policy and ranges from 87 to 125 rubles per package for crystalline powder

"Xeroform": description

This medicine is used externally only. It comes in the form of a yellow powder and has a faint odor. It has a complex effect - dries the skin and disinfects it. Due to this, it is used to treat various skin diseases.

The active ingredient is the organic salt of bismuth tribromophenolate in the form of oxide, hydroxide. The powder is slightly soluble in water and other liquids. The bismuth content by mass fraction reaches 50-55%. Moreover, the more intensely the powder is colored yellow, the more of the main component it contains.

The product is produced in glass ampoules of different weights - 5, 7 or 10 g. Sometimes pharmacies also sell xeroform-based ointment, which also contains petroleum jelly (90% by weight). Another form of release is suppositories for the treatment of anal fissures and hemorrhoids (trade name “Anuzol”).

The powder should be stored in its original packaging, away from sunlight. Keep away from children. The room temperature should be no more than 30 degrees. Anuzol suppositories are stored only in the refrigerator. The shelf life of the powder is 5 years from the date of production, candles - 2 years, subject to storage rules.

Pharmacodynamics and pharmacokinetics

When liniment is applied to the affected area, it becomes viscous. External irritants cannot cause harm, as the lesion begins to dehydrate. Because of this, skin proteins cannot react with oxygen.

The affected skin is covered with a protective film, and the infection cannot pass through this barrier.

Surface cells become active. This leads to a regenerative process.

With improved blood circulation, cells begin to divide faster and injured parts of the skin are restored.

The action of the active component leads to positive changes:

• blood circulation in the affected area is quickly restored, cells are regenerated;
• damaged skin heals;
• the inflammatory process becomes less pronounced;
• exudate is released in a reduced amount;
• Normal blood circulation is quickly restored and the epidermis is regenerated.

Due to the decrease in enzymatic activity, the affected area becomes less sensitive.

Instructions for use Xeroform

Xeroform ointment, powder and powder are used externally only. All release forms are applied to cleaned wound surfaces. According to the instructions, the powder and powder are used in a thin layer 2-3 times a day. Due to their increased hygroscopicity, they adsorb sweat, exudate, excess sebum, increase evaporation from the surface and heat transfer rates. The ointment or paste is applied to cleaned wounds and covered with 5-6 layers of gauze.

According to the instructions, you should avoid getting the powder or non-eye ointment in your eyes and wash your hands thoroughly after use. The use of the drug does not affect the concentration of attention and the speed of mental reactions, so it can be used when driving vehicles and driving dangerous mechanisms. This will not lead to slower psychomotor skills and possible accidents.

For adults

Xeroform eye ointment is placed under the lower eyelid after washing the affected eye in an amount not exceeding the head of a match. For diaper rash and bedsores, the affected area is thoroughly treated with ointment, powder or powder twice a day. If health problems occur while using the drug, or the drug does not bring the desired effect, the symptoms are not eliminated, then you should stop taking the drug and adjust the treatment regimen.

For newborns

Xeroform powder is applied to the umbilical wound or area of ​​diaper dermatitis, not covered with a bandage for better drying of the affected area. Before use, the wound is washed with hydrogen peroxide. The instructions recommend using the drug twice a day at the same time - morning and evening, until the skin has completely healed and dried out.

Drug interactions and special instructions

The drug can be used together with other medications, since the components of Xeroform do not penetrate the bloodstream and do not act systemically. Therefore, any combinations are allowed. However, when using different ointments or powders together externally, they should be applied separately and not in a mixture.

Cases of overdose are not reported in the instructions. Powder is poured in a small layer 2-3 times a day. If ingested, immediately take several tablets of activated carbon and drink plenty of water. If necessary, seek emergency help.

The drug does not affect the speed of psychomotor reactions. Therefore, it can be taken by drivers, machine operators, and moving mechanisms.

Instructions for use and general recommendations

Before applying xeroform ointment, rinse the surface to be treated and apply a disinfectant. Next, the composition itself is lightly rubbed into a thin layer, which is protected on top with a bandage or clean cloth.

It is unacceptable to drink alcohol while being treated with this drug. No direct interaction of substances was found, but it was found that alcohol significantly increases treatment time.

When used correctly, xeroform ointment accelerates tissue regeneration, narrows blood vessels in the area of ​​application and, as a result, reduces pain and swelling.

Instructions for use

Possessing pronounced effectiveness, as well as the possibility of use in complex treatment, Xeroform is easy to use and has virtually no side effects when used. The minimal number of possible side effects, even with long-term use of this external remedy, explains the constant demand for it among buyers.

A feature of the instructions for use of Xeroforms should be considered ease of use: it is enough to apply the product to the affected surface of the skin for a certain time, leave it to act, and within a short time there is a marked improvement in the condition of the skin, the elimination of inflammatory phenomena on it and the restoration of normal blood circulation. Tissue regeneration allows it to be used as a drug for skin grafting.

For adults

Duration of use - until a pronounced improvement in the condition of damaged skin is obtained. Typically, improvement occurs within 1.5-2 weeks from the start of use. However, the duration of use of the drug should be determined by the attending physician, taking into account the characteristics of the course of the identified disease and the individual characteristics of the body.

Children, newborns

Since children have hypersensitive skin and a high tendency to allergic manifestations, the frequency of applying the drug to areas with damaged skin can be reduced to 1-2 times a day. During the use of the product, you should carefully monitor the skin reaction: if any allergic manifestations are present, you must stop using the drug or replace it with a less active external agent for damaged skin.

During pregnancy and lactation

Since the drug Xeroform is highly active without the possibility of penetration into breast milk and through the placenta, its use is not prohibited during pregnancy and breastfeeding. However, due to the likelihood of allergic reactions on the part of both the woman and the child, you should monitor skin reactions to the product and, if even minor negative manifestations are detected, stop using it.

Directions for use and dosage

The effectiveness of the drug allows it to be used in combination with other medications.

Long-term use does not negatively affect the body.

Apply the product to the affected area and leave it for a while.

The skin heals, inflammatory processes disappear, and blood circulation is restored. Using this ointment, you can create a protective film on an open wound.

The dose is calculated by a dermatologist.

The product is applied throughout the day on cleansed skin. There is no need to apply a fixing bandage.

The procedure is repeated 3 times a day. You can use xeroform until the damaged skin is restored.

After 14 days you can expect improvements. In any case, regarding the duration of use, you should consult your doctor. Each person's body has its own individual characteristics.

Price

The drug can be purchased at a pharmacy or online without presenting a doctor's prescription. All release forms are stored at temperatures up to 30 degrees for five years. Approximate price for Xeroform, drugs containing it and substitutes in Moscow:

Xeroform: use for treating umbilical wounds

Xeroform powder is successfully used for a poorly healing umbilical wound in a baby. The product dries and completely heals the baby’s tender spot in a matter of days without accompanying skin irritation. In addition, this remedy does not cause discomfort to the baby, which greatly facilitates the treatment process.

To treat the umbilical wound with Xeroform powder, use the instructions for use:

1. The baby's navel is carefully treated with a solution of hydrogen peroxide.
2. Then the umbilical wound is sprinkled with powder.
3. This is done twice - in the morning and in the evening before bed.
4. Such activities are carried out until the wound is completely healed.

In addition, Xeroform perfectly eliminates diaper rash and alleviates the condition of a child with diaper dermatitis.

There is no official information on the use of Xeroform during pregnancy and lactation. Therefore, the decision to use the drug should be made by a doctor. But such precautionary measures are of a formal nature, since the reviews about Xeroform are exclusively positive and there is no data on a negative effect on the fetus.

Indications

The use of Xeroform makes it possible to quickly cope with many skin lesions accompanied by mechanical damage to the epidermis and the development of pathogenic microorganisms on the wound surfaces. The greatest effect from the use of this product is observed in the presence of inflammation on the skin, with deterioration of the skin's resistance to external aggressive influences.

The following conditions should also be considered indications for the use of the drug:

• eczema and dermatitis of various types (including Ritter), even in the acute stage;
• fungal infections, accompanied by an active increase in the affected area due to the proliferation of the fungus and the appearance of cracks and bedsores on the skin;
• frostbite, in which a destructive process is observed in damaged parts of the skin;
• sun and thermal burns with the appearance of mechanical damage;
• the presence of purulent and weeping wounds, which most often occur after surgery;
• boils, including deep and purulent ones;
• minor skin damage - cracks, abrasions, scratches.

This drug has proven itself to be excellent in the fight against blood-sucking insects - flies, mosquitoes, when applied to clean, healthy skin. Xeroform can also be used to accelerate the healing of the umbilical wound in newborns. In combination with antibacterial external agents, Xeroform has shown excellent results in the treatment of inflammatory processes in the lymph nodes and blood vessels, as well as eye diseases - in this case, the doctor prescribes an eye ointment based on Xeroform.

Indications for use

The main indications for use of the product are:

• skin dermatitis in adults and children;
• ulcerative, erosive type lesions;
• furunculosis;
• abscesses;
• eye diseases, including inflammatory ones;
• eczema;
• bedsores;
• diaper rash;
• mucosal damage;
• wounds, abrasions and other mechanical injuries to the skin;
• cracks in the surface layer;
• lymphadenitis;
• diseases of the lymphatic vessels at the acute stage;
• lymphangitis;
• repellent for the prevention of mosquito bites;
• for healing the umbilical wound in a newborn;
• injuries after surgery, including a weeping or purulent wound;
• “Xeroform” is also used to soften tissue (maceration process).

For newborns

It is possible to use the drug Xeroform in the form of baby powder for newborns.

Application:

• A small amount of the product is applied to the surface of the umbilical wound or to the area of ​​irritation (for example, from diapers).
• Covering the treated parts of the body is not recommended in order to dry out the affected areas.

The drug Xeroform has excellent astringent, antiseptic effects, and stimulates reparative processes occurring in tissues.

It is also able to reduce signs of the inflammatory process, reduce swelling and the release of liquid blood into adjacent tissue structures.

But remember that before use you should consult a specialist. Only he can prescribe the necessary application regimen specifically in your case.

Indications and prohibition for use

The medicine "Xeroform", the price of which will be presented to you below, has a drying, astringent, anti-inflammatory and bactericidal effect. Indications for the use of the powder are various injuries to the skin. These can be open wounds, bruises, bedsores, ulcers. The drug is prescribed for frostbite and burns. The composition can also be used in infants to speed up the healing of the umbilical wound. Pediatricians often prescribe powder for diaper dermatitis.

What important information does the instructions for use contain about the medicine “Xeroform” (powder)? The abstract indicates to the consumer that the medicine has contraindications. It is not allowed to use the drug if you are highly sensitive to any of its components. It is prohibited to use the powder during pregnancy and lactation. The medication should not be used by children without appropriate doctor's advice.

Xeroform indications

The drug is prescribed for the treatment of the following diseases associated with damage to the skin and mucous membranes:

• dermatitis of various origins, including diaper dermatitis in infants;
• ulcers and erosions of the skin and mucous membranes;
• eczema of various localizations;
• abscesses and skin lesions with furunculosis;
• lymphadenitis and lymphangitis;
• burns, frostbite, bedsores;
• secondary purulent wound infection in the postoperative period;
• diaper rash in adults and children;
• stopping the umbilical wound in newborns.

Analogs

Xeroform is included in several medications, so it can theoretically be replaced by them. In addition to them, there are other analogues of the drug with the same effect, but a different composition:

• Vishnevsky ointment is an antiseptic liniment containing tar, bismuth tribromophenolate and bismuth oxide complex;
• Anuzol - astringent and drying rectal suppositories based on belladonna leaf extract, bismuth tribromophenolate, bismuth oxide complex and zinc sulfate;
• Fukortsin is an antimicrobial liquid for treating wounds, containing resorcinol, acetone, boric acid, phenol;
• Chlorophyllipt – bacteriostatic and bactericidal tablets, spray, alcohol injection solution, solution for skin treatment, solution in oil based on eucalyptus leaf extract.

Release form

Yellow powder with a weak specific odor is not the only form of Xeroform. It is available in 7 g containers with instructions for use. Also in pharmacies you can find powder, yellow xeroform ointment for treating skin with 10 mg of bismuth and 90 mg of petroleum jelly with a weak specific odor, 3% eye ointment. Xeroform is included in the balsamic liniment according to Vishnevsky, and in suppositories for the treatment of hemorrhoids Anuzol. The powder additionally contains zinc oxide and streptocide. It is a white amorphous powder with a pronounced streptocidal odor.

Indications and contraindications

Xeroform is used to heal wounds and accelerate the regeneration of cells in affected tissues. It is non-toxic and does not irritate mucous membranes. According to the instructions, Xeroform is most often prescribed for the treatment of bedsores, purulent and long-term non-healing postoperative wounds, burns and frostbite, dermatitis, eczema, ulcers and diaper rash.

The drug should be used with caution during pregnancy and lactation, and in childhood. Before applying any product to a patient’s skin, it is necessary to test its effect on a healthy area of ​​skin.

Before applying any product to the patient’s skin, it is necessary to test its effect on a healthy area of ​​skin.

Contraindications and side effects

Xeroform can be used by adults and children of any age, including newborns. The drug has virtually no contraindications, except in cases of individual intolerance to the active component. During pregnancy and breastfeeding, the medicine can be used, but with caution. It is recommended to consult a doctor first.

Side effects are rare. However, in case of individual intolerance, allergic reactions may develop, including redness, itching, rash and others. In these cases, stop taking the drug and consult a doctor.

Xeroform - analogues of the drug

Xeroform is not distinguished by the existence of analogues. The drug is produced mainly by state pharmaceutical companies under the same name. Among the products that are closest in composition, only Vishnevsky’s ointment can be named.

As you can see, Xeroform helps with many diseases and injuries of the skin, it is easy to use, and it is inexpensive. It will find its own application in every home and will eliminate any injury or burn that has arisen in just a couple of days.

Sources

• https://www.syl.ru/article/333835/poroshok-kseroform-instruktsiya-po-primeneniyu-pokazaniya-sostav-analogi-otzyivyi
• https://www.receptol.ru/offers/%D0%9A%D1%81%D0%B5%D1%80%D0%BE%D1%84%D0%BE%D1%80%D0%BC/
• https://www.neboleem.net/kseroform.php
• https://dolgojit.net/kseroform.php
• https://mazikrem.ru/kseroformnaya-maz/
• https://medside.ru/kseroform
• https://apteka.ru/preparation/kseroform/
• https://oprostatite.info/preparaty/maz-kserofomnaya-instrukciya-po-primeneniyu
• https://missbagira.ru/themes/health/dlya-chego-naznachayut-kseroform-pokazaniya-protivopokazaniya-kseroform-instrukciya-po-primeneniyu