Nosological classification (ICD-10)
- J00 Acute nasopharyngitis [runny nose]
- J01 Acute sinusitis
- J03.9 Acute tonsillitis, unspecified (angina agranulocytic)
- J06 Acute upper respiratory tract infections of multiple and unspecified localization
- J20 Acute bronchitis
- J31 Chronic rhinitis, nasopharyngitis and pharyngitis
- J32 Chronic sinusitis
- J35.0 Chronic tonsillitis
- J40 Bronchitis, not specified as acute or chronic
- J42 Chronic bronchitis, unspecified
Side effects
From the digestive system: digestive tract disorders (including stomach pain, heartburn, nausea, diarrhea), mild bleeding of the gums.
From the respiratory system: mild nosebleeds.
Skin/immune system disorders: hypersensitivity reactions (including rash, urticaria, itching of the skin and mucous membranes). In isolated cases, severe hypersensitivity reactions with facial swelling, shortness of breath and decreased blood pressure are possible).
From the hepatobiliary system: increased liver function indicators. A cause-and-effect relationship between the increase in these indicators and the use of the drug has not been demonstrated.
Directions for use and doses
Inside, 30 minutes before meals, with a small amount of water. When dosing the drug, the bottle should be held vertically, if necessary, lightly tapping the bottom of the bottle.
Adults and children over 12 years old - 20-30 drops 3 times a day; children 6–12 years old - 10–20 drops 3 times a day; children from 1 to 6 years old - 5-10 drops 3 times a day.
The average duration of treatment is 10 days. After the symptoms of the disease disappear, it is recommended to continue treatment for several days to prevent relapse.
Umkalor 50 ml solution for oral administration
APPROVED by the order of the Chairman of the Pharmaceutical Control Committee of the Ministry of Health of the Republic of Kazakhstan dated “___” _____________200___. No. __________________________ Instructions for medical use of the drug Umckalor Umckalor® Trade name Umckalor Umckalor® International nonproprietary name No Dosage form Oral solution 20 ml, 50 ml Composition 10 g of solution contain the active substance - extract from the roots of Pelargonium sidoides (1:8 - 10 ) 8.0 g; extractant: ethyl alcohol 11% excipient - glycerin 85% 2.0 g; alcohol content 12 vol. %. Description Light brown to reddish brown liquid. Pharmacotherapeutic group Drugs used for coughs and colds ATC code R05 Pharmacological properties Pharmacokinetics Umkalor is a complex mixture of many components, considered as a whole as an active substance. There are no data on the pharmacokinetic properties of individual substances. Pharmacodynamics The drug Umkalor contains an extract from the roots of the South African plant Pelargonium sidoides. In vitro studies confirmed the following effects of the drug Umkalor: stimulation of nonspecific protective mechanisms: - stimulation of the vibration frequency of the villi of the ciliated epithelium, - modulation of the synthesis of interferon and anti-inflammatory cytokines, - stimulation of the activity of NK cells, - stimulation of phagocytosis, expression of adhesive molecules, chemotaxis; antimicrobial activity: - moderate direct antibacterial and antiviral activity, - enhancement/inhibition of adhesion of group A streptococci to dead/living epithelial cells, - inhibition of ß-lactamase activity; cytoprotective properties: - inhibition of the activity of human leukocyte elastase, - antioxidant properties. Indications for use Acute and chronic infections, especially infections of the respiratory tract and ear, nose and throat area, for example, bronchitis, sinusitis, tonsillar tonsillitis, nasopharyngitis. Directions for use and dosage Unless otherwise directed by your doctor, the following dosage regimen is recommended: adults and children over 12 years of age: 20-30 drops three times a day; children from 6 to 12 years: 10-20 drops three times a day; children from 1 to 5 years: 5-10 drops three times a day. The drops should be taken with a small amount of liquid in the morning, afternoon and evening. 10 drops correspond to 0.16 ml of solution. The course of treatment is 7 – 10 days. After the symptoms have subsided, it is recommended to continue taking the drug for several more days to prevent relapse of the disease. The duration of treatment should not exceed 3 weeks. If your condition does not improve within one week, if you continue to have a high fever for several days, or if you develop shortness of breath or bloody sputum, contact your doctor immediately. Side effects Uncommon: - gastrointestinal disorders (stomach pain, heartburn, nausea or diarrhea), Rare: - light bleeding from the gums or nose, - hypersensitivity reactions (skin rashes, urticaria, itching of the skin and mucous membranes). Very rare: - serious hypersensitivity reactions with facial swelling, shortness of breath and a drop in blood pressure. There are isolated reports of signs of liver dysfunction after taking Umkalor®; a cause-and-effect relationship between these effects and the use of the drug has not been established. Contraindications - increased tendency to bleeding - use of anticoagulants - severe liver and kidney diseases - hypersensitivity to the active substance or other components of the drug - children under 1 year of age - pregnancy, lactation. Drug interactions To date, there are no reports of interactions between the drug Umkalor and other drugs. Due to the possible effect of the drug on blood coagulation parameters, the possibility cannot be excluded that, when used simultaneously, it may enhance the effect of anticoagulants such as phenprocoumon and warfarin. Special instructions Umkalor contains 12 vol.% alcohol. When taking the drug in accordance with the instructions, 0.02-0.04-0.06 g of alcohol is taken with each dose (10-20-30 drops), which can lead to health risks for patients with liver diseases and cerebral diseases, patients with alcoholism , epilepsy, pregnant, lactating women and children. Liquid plant extracts are characterized by a tendency to become cloudy after long-term storage, which, however, does not in any way affect the effectiveness of the drug. Since Umkalor solution is a natural product, turbidity and slight variations in the color and taste of the drug may be observed. Pregnancy and lactation Due to the lack of sufficient experience with the use of the drug Umkalor in pregnant women and breastfeeding mothers, it should not be used during pregnancy and lactation. Features of the effect on the ability to drive a vehicle or potentially dangerous mechanisms No effect Overdose Not identified Release form and packaging 20 or 50 ml in dark glass bottles, equipped with a polyethylene dropper, with a screw cap with first opening control. 1 bottle, along with instructions for use in the state and Russian languages, is placed in a cardboard box. Storage conditions Store at a temperature not exceeding 30 oC. Keep out of the reach of children! Shelf life 3 years Shelf life after first opening the package 3 months Do not use after expiration date. Conditions for dispensing from pharmacies Without a prescription Manufacturer ISO-Artsneimittel GmbH & Co. KG Bunsenstrasse 6 -10, 76275 Ettlingen, Germany Marketing authorization holder Deutsche Homeopathy-Union DCU-Artzneimittel GmbH & Co. KG Germany, 76227 Karlsruhe, Ottostrasse 24. Tel. +49 / 721 / 4093 236
special instructions
During storage, liquid plant extracts tend to become cloudy, but this does not affect their pharmacological effectiveness. Since Umkalor is a natural product, slight changes in the color and taste of the drug are possible.
Due to the ethanol content in the drug (12 percent by volume), it must be taken into account that the maximum single dose for children over 12 years of age and adults contains 0.125 g of absolute ethyl alcohol, the maximum daily dose for children over 12 years of age and adults contains 0.375 g of absolute ethyl alcohol alcohol A single dose for children under 12 years of age contains less than 0.1 g of absolute ethyl alcohol.
In case of alcoholism, head injury, brain diseases, impaired liver and kidney function (no experience of use), caution should be exercised in children from 1 year of age.
Impact on the ability to drive a car and operate machinery. When using the drug, caution should be exercised when engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions (including driving vehicles, working with moving mechanisms).
Pharmacological properties
Pharmacodynamics.
The drug umkalor contains an original extract from the roots of pelargonium (pelargonium sidoides). a standardized phytoextract (eps 7630), which has no analogues*, combines proven pronounced antiviral, antibacterial, anti-inflammatory and immunomodulatory effects, is effective at all stages of the etiopathogenesis of ARVI, prevents the progression of diseases and the development of complications. In studies, after ingestion of the extract, inhibition of the course of the disease was noted.
In vitro tests confirmed the following effects of the drug Umkalor:
stimulation of nonspecific defense mechanisms:
- stimulation of the frequency of contraction of the ciliated epithelium;
- modulation of the synthesis of interferon and pro-inflammatory cytokines;
- stimulation of cell activity - natural killer cells;
- stimulation of phagocytes, expression of adhesion molecules, chemotaxis;
antimicrobial effects:
- moderate direct antibacterial and antiviral properties;
- growth/inhibition of adhesion of A-streptococci to desquamative/living epithelial cells;
- β-lactamase inhibition;
cytoprotective properties:
- inhibition of human leukocyte elastase;
- antioxidant properties.
Pharmacokinetics. The drug is a complex mixture of many components, which is generally considered as an active substance. There are no data on the pharmacokinetics of the drug yet.
*NB! Umkalor has no analogues in Ukraine due to the fact that the extract EPs 7630 for the production of the drug Umkalor is not sold to other manufacturers, thus its characteristics cannot be repeated in other drugs (APTEKA Weekly No. 7 (978) “Herbal medicines: brands and their analogues - what do they have in common and what are the differences?”).
Manufacturer
Dr. Wilmar Schwabe GmbH&Co.KG. Wilmar-Schwabe-Strasse 4 76227 Karlsruhe, Germany.
Tel.: +49 (721) 40050; fax: +49 (721) 4005-202.
Registration certificate holder: ISO-Artsnaimittel GmbH&Co.KG. Bunsenstrasse 6-10, 76275, Ettlingen, Germany.
Tel.: +49 7243-106-03; fax: +49 7243-106-169.
Representative office in Russia/organization receiving consumer complaints: 117513, Moscow, st. Ostrovityanova, 6.
Tel..
Storage conditions
Umkalor district at a temperature not exceeding 30 °C.
Note. In extracts of plant origin in the form of solutions, turbidity is possible over time, which does not affect the effectiveness of the drug. Since Umkalor is a herbal medicine, slight changes in its color and taste are possible.
Umkalor syrup. Does not require special storage conditions. After opening the bottle, the shelf life is 6 months.
Umcalor tablets. Does not require special storage conditions.
Exclusive distributor: PJSC "Naturfarm", st. Lesnaya, 30a, Kyiv, Pushcha-Voditsa, 04075; telephone.
Supplier: Alpen Pharma AG (Switzerland).
The product description is certified by the manufacturer Dr. Wilmar Schwabe
.
Verified by
Likar Turumkulova Irina
Note!
Description of the drug Umkalor syrup fl. 100ml on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
