The human body at any age contains about 1200 mg of calcium. It is mainly found in the teeth and skeletal system. Present in small quantities in urine, blood and saliva. With frequent physical activity and during pregnancy, the body needs more calcium. To compensate for its deficiency, experts often prescribe Calcium D3 Nycomed.
Symptoms of mineral deficiency
Calcium deficiency can be determined by the following signs:
- pain in the bones, which is explained by weight loss and thinning of the bones;
- deterioration of hair condition (dull, brittle);
- problematic skin of the face and body;
- pronounced toxicosis in pregnant girls;
- weakened immune system;
- formation of tartar and caries;
- the appearance of fungus on the nails.
The drug Calcium D3 Nycomed will help compensate for the lack of the mineral.
Signs of mineral deficiency in the body
The role of calcium in the human body is obvious: it is an integral element of bone tissue, nails and hair. Nutritionists, depending on weight, set the daily requirement at 500-1100 mg of the mineral. It promotes beautiful hair and strong nails.
Reviews of the drug indicate that it is popular among patients experiencing calcium deficiency.
Signs of a mineral deficiency include:
- pain in the bones, which is associated with bone loss;
- brittle and dry hair, its frequent loss;
- problematic skin;
- slow weight gain in children;
- toxicosis in pregnant women;
- miscarriages;
- deterioration of the condition of teeth, the appearance of dental diseases;
- nail fungus.
Signs of excess calcium
Excess calcium can be associated with taking medications, as well as as a result of the appearance of malignant or benign neoplasms. This can be determined by the following signs:
- confused mind, problems with coordination;
- gag reflex after eating;
- stomach upset;
- increased weakness;
- problems with the heart and blood vessels;
- kidney diseases.
How much calcium should be added
Remember that you usually only need 1000-1200 mg of calcium each day. There is no point in getting more calcium. It might even be dangerous. There are recommendations that the maximum daily calcium intake should not be more than 2000-2500 mg per day. To avoid the danger of getting too much calcium and causing constipation, hypercalcemia, calcium accumulation in soft tissues, problems with the absorption of iron and zinc, it is not recommended to receive more than 1400 mg of calcium per day for a long time.
If you cannot supplement your diet with foods high in calcium (dairy products, leafy greens, nuts, beans and tofu), you can take up to 500-1000 mg of elemental calcium from supplements.
Contraindications and adverse reactions
After taking Calcium D3 Nycomed, undesirable reactions may occur:
- from the gastrointestinal tract: upset stomach, vomiting, nausea;
- from the central nervous system: nervousness, increased feeling of agitation;
- from the metabolic side: hypercalcemia, manifested by fatigue, problems with the heart and blood vessels;
- on the skin: an allergic reaction manifested by various rashes.
The drug is strictly contraindicated in the following cases:
- excess calcium in the blood;
- chronic renal failure;
- active tuberculosis;
- allergy to the substances included in the composition, including fructose.
Calcium-D3 nycomed
Release form, composition and packaging
Chewable tablets (orange), uncoated, round, biconvex, white; with orange aroma; may have small inclusions and uneven edges. 1 tab. colecalciferol (Vit. D3) 5 mcg (200 IU) calcium carbonate 1.25 g, which corresponds to an elemental calcium content of 500 mg. Excipients: sorbitol, isomalt, povidone, magnesium stearate, aspartame, orange oil, mono- and diglycerides of fatty acids.
Chewable tablets (mint), uncoated, round, biconvex, white; with mint flavor; may have small inclusions and uneven edges. 1 tab. colecalciferol (Vit. D3) 5 mcg (200 IU) calcium carbonate 1.25 g, which corresponds to an elemental calcium content of 500 mg. Excipients: sorbitol, mint flavor, povidone, magnesium stearate, aspartame.
Clinical and pharmacological group: A drug that regulates the metabolism of calcium and phosphorus.
pharmachologic effect
A combined drug that regulates the exchange of calcium and phosphorus in the body (in bones, teeth, nails, hair, muscles). Reduces resorption (resorption) and increases bone density, replenishing the lack of calcium and vitamin D3 in the body, necessary for the mineralization of teeth. Calcium is involved in the regulation of nerve conduction, muscle contractions and is a component of the blood coagulation system.
Vitamin D3 (colecalciferol) increases calcium absorption in the intestines. The use of calcium and vitamin D3 prevents an increase in the production of parathyroid hormone, which is a stimulator of increased bone resorption (leaching of calcium from the bones).
Pharmacokinetics
Vitamin D3 is absorbed in the lower intestine. Calcium is absorbed in ionized form in the proximal small intestine through an active vitamin D-dependent transport mechanism.
Indications
- prevention and treatment of calcium and/or vitamin D3 deficiency;
- prevention and complex therapy of osteoporosis (including menopausal, senile, steroid, idiopathic).
Dosage regimen
adults are prescribed 1 tablet. 2-3 times a day, for the prevention of osteoporosis - 1 tablet. 2 times/day. For calcium and vitamin D deficiency, adults and children over 12 years of age are prescribed 1 tablet. 2 times/day, children aged 5 to 12 years - 1-2 tablets/day, children aged 3 to 5 years the dosage regimen is set individually.
The tablet can be chewed or dissolved and taken with meals.
Side effect
- From the digestive system: possible constipation, diarrhea, flatulence, nausea, abdominal pain.
- Metabolism: hypercalcemia, hypercalciuria. Other: allergic reactions.
Contraindications
- hypercalcemia;
- hypercalciuria;
- nephrolithiasis;
- hypervitaminosis D;
- severe renal failure;
- active form of tuberculosis;
- sarcoidosis;
- hypersensitivity to the components of the drug.
The dosage form of the tablet is not used in children under 3 years of age.
Pregnancy and lactation
Caution should be exercised when prescribing the drug during pregnancy and lactation. During pregnancy, the daily dose of the drug should not exceed 1500 mg of calcium and 600 IU of vitamin D3. Hypercalcemia, which develops against the background of an overdose during pregnancy, can cause defects in the mental and physical development of the child.
Vitamin D and its metabolites can be excreted in breast milk, so additional calcium and vitamin D intake from other sources must be considered for mother and baby.
Use for renal impairment
The drug is contraindicated in severe renal failure.
special instructions
Calcium-D3 Nycomed tablets contain aspartame, which is transformed into phenylalanine in the body, so the drug should not be taken if you have phenylketonuria.
When using the drug Calcium-D3 Nycomed in patients receiving cardiac glycosides and/or diuretics, it is necessary to monitor the concentration of calcium and creatinine in the blood serum. In case of increased concentration of calcium or creatinine in the blood serum, as well as in case of hypercalciuria exceeding 7.5 mmol/day (300 mg/day), the dose of the drug should be reduced or treatment should be temporarily stopped. To avoid overdose, additional vitamin D3 intake from other sources must be taken into account.
Eating foods containing oxalates (sorrel, spinach) and phytin (cereals) reduces calcium absorption, so you should not take Calcium-D3 Nycomed within 2 hours after taking sorrel, spinach, cereals.
Calcium-D3 Nycomed should be used with caution in immobilized patients with osteoporosis due to the risk of developing hypercalcemia.
Overdose
Symptoms: anorexia, thirst, polyuria, loss of appetite, dizziness, fainting, weakness, nausea, vomiting, hypercalciuria, hypercalcemia, hypercreatininemia; with long-term use in excessive doses - calcification of blood vessels and tissues.
Treatment: the drug should be discontinued immediately. It is recommended to introduce large amounts of fluid into the body, the use of “loop” diuretics (for example, furosemide), corticosteroids, calcitonin, and bisphosphonates. The patient should be warned that if signs of overdose appear, they should consult a doctor.
Drug interactions
- When used simultaneously with phenytoin or barbiturates, a decrease in the activity of vitamin D3 is possible.
Calcium preparations can potentiate the therapeutic and toxic effects of cardiac glycosides, therefore, with the simultaneous use of the drug Calcium-D3 Nycomed and cardiac glycosides, monitoring of the ECG and the clinical condition of the patient is necessary. Calcium and vitamin D3 preparations can increase the absorption of tetracyclines from the gastrointestinal tract, therefore the interval between doses of the drug Calcium-D3 Nycomed and antibiotics of the tetracycline group should be at least 3 hours.
- When used simultaneously with bisphosphonates or sodium fluoride, their absorption may be reduced, so it is recommended to take Calcium-D3 Nycomed no earlier than 2 hours after these medications.
GCS reduce calcium absorption, so patients receiving GCS may require an increase in the dose of Calcium-D3 Nycomed.
- When used simultaneously with cholestyramine or laxatives based on mineral or vegetable oil, the absorption of vitamin D3 may be reduced.
- When used simultaneously with thiazide diuretics, the risk of developing hypercalcemia increases due to increased tubular reabsorption of calcium. Furosemide and other “loop” diuretics, on the contrary, increase calcium excretion by the kidneys.
Storage conditions and periods
The drug should be stored in a tightly closed bottle, in a dry place, at a temperature not exceeding 25°C. Shelf life: 3 years.
Is it possible to drink Calcium D3 Nycomed while breastfeeding?
Calcium D3 Nycomed is also allowed to be taken during lactation. The active substances pass into breast milk. That is why it is important to correctly consider other sources of mineral and vitamin D. When treating with this medication, it is worth familiarizing yourself with the situations in which excess calcium may develop. This will prevent a similar situation in the mother and her baby.
With proper calcium intake, the baby develops a strong skeletal system, the likelihood of fractures decreases, and girls grow beautiful hair and strong nails.
When to think about calcium deficiency
If you have a lack or deficiency of vitamin D, if you don’t get enough sun exposure, drink little or no milk and dairy products, for example due to an allergy or lactose intolerance, follow special types of diet (high protein diet, veganism, etc.) .), if you are addicted to caffeine (coffee, strong tea, chocolate), then you should think about the lack of calcium intake from food. By the way, foods such as spinach, greens, rhubarb, and beans, although rich in calcium, also contain oxalic and phytic acids. As a result, insoluble calcium-oxalate and calcium-phytate complexes are formed, which does not allow calcium to be absorbed.
Diseases of the kidneys, parathyroid glands and inflammatory bowel diseases also disrupt the calcium balance in the body.
Drug interactions
If you take the medication with other medications to treat problems with the heart and blood vessels, toxic effects on the cardiovascular system and liver may develop. In the case of simultaneous use of Calcium D3 Nycomed and antibiotics, there may be a deterioration in the absorption of the latter.
When taken simultaneously with multivitamin complexes, excess calcium in the blood may appear, and the functioning of the entire body may deteriorate.
If there is an urgent need to take these drugs together, you should consult a specialist in advance.
Interaction with other drugs
If the drug is taken together with other medications to treat heart and vascular diseases, toxic effects on the liver, heart and blood vessels often occur. If you still can’t stop taking them in parallel, then you should regularly monitor the level of minerals in the blood.
If you take the drug with antibiotics of the tetracycline group, the latter will be poorly absorbed. You should wait at least 3-4 hours between doses.
According to doctors, when taken together with multivitamin supplements, there may be an excess of zinc in the blood and problems in the functioning of the cardiovascular system. You should take vitamins and minerals with caution so as not to lead to an overabundance of the latter.
