Pharmacodynamics and pharmacokinetics
This drug is a combined antispasmodic analgesic , with an effect due to its constituent components.
Metamizole sodium is a derivative of Pyrazolone, a well-known analgesic -antipyretic , which has a significant analgesic, antipyretic and weak anti-inflammatory effect, which is associated with inhibition of prostaglandin production.
Fenpiverinium bromide is an m-anticholinergic blocker , which has an additional antispasmodic effect on smooth muscles.
Pitophenone is a myotropic antispasmodic that has a direct effect directly on the smooth muscles of all internal organs, promoting its relaxation.
Information on the pharmacokinetics of this drug is not provided.
HEADACHE AND MIGRAINE
The most common type of pain is headache. More than 70% of the population of developed countries in Europe and America complain of episodic or chronic headaches.
Main reasons:
- psycho-emotional or physical stress tension headache (50-70% of all headache cases)
- spasm or decrease in cerebral vascular tone, incl. with hypotension and changes in atmospheric pressure (vasodilation - cluster headache)
- migraine (10–15% of the world's population)
Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.
Indications for use of Spazmalin
The main indications for use are:
- pain syndromes due to spasms of smooth muscles inside the body, for example, with renal or biliary colic , algodismenorrhea ;
- carrying out short-term symptomatic therapy for neuralgia, arthralgia, myalgia , and so on.
Spasmalin injections are also used as an adjuvant to reduce pain after surgical or diagnostic procedures.
The tablets are often taken for headaches or migraines .
JOINT PAIN
Everyone is familiar with the terms “arthritis” and “arthrosis”.
“Arthritis” is an inflammatory disease of the joints.
“Arthrosis” is a disease of the joints of a degenerative-dystrophic nature.
With these two pathological conditions, sooner or later joint pain occurs.
This pain constrains the joints, prevents normal movement, and disrupts the natural and habitual rhythm of life.
The drug SPAZMALIN® is intended for reliable relief of joint pain of various locations and origins. The components of the drug can quickly relieve pain.
Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.
Contraindications for use
It is recommended not to use the drug if:
- granulocytopenia;
- diseases of the hematopoietic system;
- severe dysfunction of the liver and kidneys;
- angle-closure glaucoma;
- deficiency of glucose-6-phosphate dehydrogenase;
- tachyarrhythmias;
- benign prostatic hyperplasia;
- lactation, pregnancy;
- children less than 3 months old and weighing up to 5 kg, and so on.
MUSCLE PAIN
The causes of muscle pain can be very different: inflammation, injuries (sprains, tears), autoimmune processes, etc. It is not recommended to endure muscle pain for a long time, as it can lead to further dysfunction of the musculoskeletal system.
The painkiller SPAZMALIN® will help you cope with muscle pain.
Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.
Side effects
When treated with Spasmalin, side effects may occur that affect the functioning of the digestive, cardiovascular, nervous, excretory and hematopoietic systems. The most common symptoms are: dry mouth, discomfort in the gastrointestinal tract, decreased blood pressure, cyanosis, tachycardia, thrombocytopenia, leukopenia , dizziness , impaired renal function, and so on.
Allergic reactions in the form of itching are possible .
NEURALGIA
Neuralgia is a lesion of a peripheral nerve, usually manifests itself in the form of acute, severe, burning, piercing pain in the area of innervation of the affected nerve.
If neuropathies and neuritis are characterized by symptoms of loss of nerve function (i.e., decreased sensitivity or motor activity), then neuralgia is characterized by symptoms of irritation (in addition to pain, burning and tingling sensations, increased sensitivity). The most common are neuralgia of the cranial (trigeminal, glossopharyngeal) and spinal (intercostal) nerves.
The causes of neuralgia can be: hypothermia, inflammatory diseases, trauma, tumors, intoxication and even stress.
To relieve attacks of neuralgia, you can use a combination of acetylsalicylic acid, paracetamol and caffeine, which are contained in the drug SPAZMALIN®. It will help you quickly get rid of acute pain.
Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.
Spasmalin, instructions for use (Method and dosage)
The tablets are taken orally, preferably after meals. For adults and children over 15 years of age, a daily dosage of 1-2 tablets is prescribed for 2-3 times a day. At the same time, taking more than 6 tablets per day is not allowed. You can take the tablets for no more than 5 days.
If you need to increase the dose or duration of treatment, then medical supervision is necessary. Treatment of children is possible only as prescribed by a specialist. The average dose for young patients 6-8 years old is ½ tablet, 9-12 years old – three-quarters of a tablet, and children 13-15 years old can take one tablet 2-3 times a day. Dosage changes can only be made by the attending physician.
The drug solution is used for intravenous or intramuscular administration. Injection into a vein is performed slowly, using no more than 2 ml of the drug. When administered into a muscle, 2-5 ml of the drug is prescribed for 2-3 times a day.
It should be noted that the daily dose cannot be more than 2 ampoules. The average duration of therapy is 5 days.
Mixing Spazmalin solution and any other medicine in one syringe is not allowed.
SPASM OF SMOOTH MUSCLE OF INTERNAL ORGANS
This is a common cause of abdominal pain, especially in people with chronic diseases of the gastrointestinal tract.
Spasm of smooth muscles provokes intestinal, biliary and renal colic. Occurs with biliary dyskinesia, after surgery to remove the gallbladder and with chronic colitis. The antispasmodic drug SPAZMALIN® is effective for relieving spasms. Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.
Interaction
The combination of Spazmalin with some non-opioid analgesics can cause mutually enhanced effects.
Simultaneous use of tricyclic antidepressants, oral contraceptives, Allopurinol disrupts the metabolism of metamizole sodium, significantly increasing its toxicity.
Combinations with barbiturates, phenylbutazone and other inducers of microsomal enzymes may weaken the effectiveness of metamizole sodium.
The drug also reduces the concentration of Cyclosporine in the blood plasma .
Tranquilizers and sedatives often enhance the analgesic effect of Spazmalin.
Simultaneous use with histamine H1 receptor blockers, phenothiazines, butyrophenones, Quinidine and Amantadine enhances the m-cholinolytic effect of these drugs.
THORACIC RADILE SYNDROME (RADICULOPATHY)
A common neurological syndrome that occurs due to compression (compression) of the spinal nerve roots at the level of the thoracic spine.
This syndrome is usually observed with spinal osteochondrosis, spina bifida, spinal compression fracture, spondyloarthrosis and other spinal lesions. Thoracic radicular syndrome is usually manifested by pain in the back, girdle pain in the chest, and sometimes there are sensations of characteristic pain in the heart or stomach (such pain does not decrease after the use of cardiac drugs and antacids, but disappears only after treatment of the radicular syndrome). The pain intensifies with movement and lifting heavy objects. In the area of innervation of the affected nerve, sensitivity and muscle function (hypo- and atrophy), as well as the functioning of the abdominal organs, may be impaired.
SPAZMALIN® helps to reliably relieve this type of pain.
Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.
Analogs
Level 4 ATC code matches:
Analdim
Reopirin
Tempalgin
Spazgan
Benalgin
Pentalgin ICN
Pentalgin N
Pentalgin
Analgin
Renalgan
Tetralgin
Maxigan
Sedal-M
Piralgin
Baralgin M
Sedalgin Plus
Baralgetas
Revalgin
Andipal
The main analogues: Baralgetas, Bral, Renalgan, Spazgan, Spazmalgon, Spazmil-M, Spazmoblok, Spazmogard and Trinalgin.
ALGODISMENorrhea (PAINFUL MENSTRUATIONS)
Algodismenorrhea - painful menstruation, expressed by cramping or aching pain in the lower abdomen, in the lumbar and sacral regions of the spine; may be accompanied by general malaise and decreased ability to work.
The most common causes of algodismenorrhea are pelvic inflammatory diseases, endometriosis, uterine fibroids, genital infantilism, as well as hormonal and metabolic disorders. Algodysmenorrhea is more often observed in young women (which is associated with the functional immaturity of the reproductive system), but can cause serious discomfort in adulthood.
Treatment of algodismenorrhea usually requires an integrated approach and primarily consists of eliminating the causes that cause it and normalizing hormonal status.
Analgesics and non-steroidal anti-inflammatory drugs are widely used to relieve pain.
SPAZMALIN® is able to relieve pain during menstruation. The components of the drug help to quickly cope with pain.
Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.
Reviews of Spasmaline
It should be noted that reviews of Spazmaline are not common on the Internet. Some users are completely unfamiliar with this drug and usually use its analogue, Spazmalgon, which also has an antispasmodic effect.
Also on medical forums you can find messages from users who are interested in what Spazmalin helps with, although many people understand its action based on the name.
However, everyone who has used this drug notes that it helps especially well in relieving menstrual pain , as well as pain in diseases of the genitourinary system, for example, cystitis . Usually, taking just 2 tablets helps relieve the condition and eliminate pain. At the same time, women talk about its good tolerance, that is, no side effects appeared.
As for experts, they recommend not to abuse any means that have an antispasmodic effect. The fact is that, despite their high effectiveness, when used regularly to relieve pain, this medicine can have a negative effect on the body. Moreover, as a result of relieving pain syndromes, the development of a serious disease may not be detected in a timely manner. Therefore, drugs with similar effects should be used only as prescribed by a doctor.
TOOTHACHE
Toothache often comes into our lives. Its causes are varied: from damage to the enamel, inflammation of the tooth tissue and its ligaments, to injuries. Toothache can be uneven, shooting, with echoes in the ear. Your whole head may seem to hurt. Of all types of toothache, acute pain brings the greatest suffering to a person.
Painkiller SPAZMALIN® will help relieve toothache of various origins. The components of the drug can quickly relieve pain.
Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.
Spazmalin price, where to buy
The drug in ampoules of 5 ml for 5 pieces can be purchased at a price of 105 rubles.
The medicine in tablets for 20 pieces costs from 127 rubles.
- Online pharmacies in RussiaRussia
ZdravCity
- Spasmaline tablets 20 pcs.Torrent Pharmaceuticals Ltd
RUB 144 order - Spasmaline tablets 100 pcs.Torrent Pharmaceuticals Ltd
470 rub. order
LUMBAGO AND SCHIASIA
Lumbago (from the Latin lumbus - lower back) is an attack of acute pain (“lumbago”) and muscle tension in the lower back (lower back), usually occurring during physical exertion, bending over or lifting heavy objects. At rest and in a lying position on a hard surface, the acute pain subsides. The most common causes of lumbago: osteochondrosis and spondyloarthrosis of the lumbar spine.
SCHIAS (ischia - seat) - pinching and inflammation of the sciatic nerve, accompanied by acute and burning pain in its projection to the lower extremities.
The drug SPAZMALIN® will help cope with acute pain due to lumbago and sciatica. The combination of active components of the drug can quickly relieve pain.
Directions for use and doses
The drug is taken orally after meals, 1-2 tablets 2-3 times a day. The maximum daily dose is 6 tablets. The break between doses of the drug should be at least 4 hours. To reduce the irritating effect on the gastrointestinal tract, the drug should be taken after meals with water, milk, or alkaline mineral water. Before using the drug SPAZMALIN®, read the instructions.