Pain-relieving lozenges, tablets and lozenges are in constant demand, because discomfort in the throat and mouth is one of the most common symptoms of colds and acute respiratory viral infections. At the same time, most drugs from this group are sold without a doctor’s prescription, which means that first-generation companies have a real opportunity to help the client with their choice and increase sales. The success of the consultation largely depends on how well pharmacists know about numerous antiseptics for sore throats. In our tables, we have compactly and clearly provided maximum data on the properties of drugs in this group.
All local drugs for the treatment of sore throat can be divided into monocomponent (see point 1 of this review) and multicomponent (point 2). Among the latter, it is worth highlighting bacterial lysates (Table 3), which belong to the group of immunomodulators and act by increasing the number of immunocompetent cells, increasing the production of lysozyme, interferon and secretory immunoglobulin A in saliva. The composition of bacterial lysates corresponds to the pathogens that most often cause inflammatory processes in the oral cavity and pharynx.
The vast majority of local drugs for sore throat have a combined composition, which may include antiseptic components (this is the basis of almost any drug), antibiotics, anesthetics, less often - NSAIDs, as well as other components, for example, essential oils.
Composition of monocomponent drugs for sore throat
| Compound | Name |
| Antiseptic | |
| Acetylaminonitropropoxybenzene | Falimint |
| Ambazon | Faringosept |
| Cetylpyridinium chloride monohydrate | Septolete Neo |
| Gramicidin S | Gramicidin S |
| NSAIDs | |
| Benzydamine hydrochloride | Tantum Verde |
| Flurbiprofen | Strepsils Intensive |
Composition of multicomponent drugs for sore throat
| Name | Antiseptic | Antibiotic | Anesthetic | NSAIDs | Vitamins | Other components |
| Dr. Theiss Angi Sept | Dichlorobenzyl alcohol | — | — | — | — | Menthol, anethole, peppermint oil |
| Astrasept | Amylmetacresol + dichlorobenzyl alcohol | — | — | — | — | — |
| Agisept | — | — | — | — | — | |
| Hexoral Tabs classic | — | — | — | — | — | |
| Gorpils | — | — | — | — | — | |
| Rinza Lorsept | — | — | — | — | — | |
| Strepsils | — | — | — | — | — | |
| Strepsils with a warming effect | — | — | — | — | — | |
| Strepsils with cooling effect | — | — | — | — | — | |
| Suprima-ENT | — | — | — | — | — | |
| Hexoral Tabs Extra | — | Lidocaine | — | — | — | |
| Rinza Lorcept Anesthetics | — | — | — | — | ||
| Strepsils Plus | — | — | — | — | ||
| Strepsils with vitamin C | — | — | — | Ascorbic acid | — | |
| Neo-Angin | — | — | — | — | Levomenthol | |
| Strepsils with menthol and eucalyptus | — | — | — | — | ||
| Grammidin for children | Cetylpyridinium chloride | Gramicidin S | — | — | — | — |
| Grammidin neo | — | — | — | — | ||
| Grammidin with neo anesthetic | Oxybuprocaine hydrochoride | — | — | — | ||
| Septolete Plus | — | Benzocaine | — | — | — | |
| Theraflu Lar Menthol | — | Lidocaine hydrochloride | — | — | — | |
| Novosept Forte | — | Tetracaine hydrochloride | — | — | Zinc sulfate | |
| Septolete Total | — | — | Benzydamine hydrochloride | — | — | |
| Laripront | Dequalinium chloride | — | — | — | — | Lysozyme hydrochloride |
| Sebidin | Chlorhexidine hydrochloride | — | — | — | Ascorbic acid | — |
| Anti-Angin Formula | — | Tetracaine | — | — | ||
| Hexalize | Biclotymol | — | — | — | — | Enzyme Lysozyme + anti-inflammatory enoxolone |
| Septogal | Benzalkonium chloride | — | — | — | — | Menthol, thymol, mint oil, eucalyptus oil |
| Septolete, Septolete D | — | — | — | — | Peppermint oil, eucalyptus, levomenthol, thymol | |
| Stopangin 2A, Stopangin 2A forte | — | Tyrothricin (1 mg and 2 mg in Stopangin 2A and Stopangin 2A forte) | Benzocaine | — | — | — |
| Grammidin with neo anesthetic | — | Gramicidin S | Oxybuprocaine hydrochloride | — | — | — |
| Lysobacter | — | — | — | — | Pyridoxine hydrochloride | Lysozyme |
Sage tab d/rassas No. 30 implovit (dietary supplement)
Compound
Sweetener sorbitol, sage extract - 25 mg, marshmallow extract - 25 mg, plantain extract - 25 mg, ascorbic acid (vitamin C) - 25 mg, talc (anti-caking agent), stearic acid (stabilizer), natural chlorophyll dye, sage essential oil 4 mg, calcium stearate (anti-caking agent), Honey flavoring, menthol. The daily dose of the product (3-8 tablets) contains:
| Component | Content, mg | % of recommended level * / adequate level of consumption ** |
| Vitamin C | no less than 66-176 | 111-293 *(***) |
| Menthol | not less than 3.6-9.6 | 18-48 ** |
| Tannins | at least 45-120 | 15-40 * |
* according to TR CU 022/2011 (Appendix 2); ** according to the “Unified Sanitary-Epidemiological and Hygienic Requirements for Goods Subject to Sanitary-Epidemiological Surveillance (Control)” (Chapter II, Section 1, Appendix 5); *** does not exceed the upper permissible intake level of vitamin C - 900 mg.
Contraindications
Individual intolerance to product components, pregnancy, breastfeeding.
It is recommended to consult a doctor before use.
Directions for use and doses
Adults: 1-2 tablets 3-4 times, dissolving during meals.
special instructions
Dietary supplement (dietary supplement). Not a medicine.
Action
Sage is known primarily for its active participation in the fight against microorganisms and inflammatory processes. Cineole is a component of sage essential oil, has phytoncidal properties and is involved in the neutralization of bacteria. Sage also has antiseptic properties due to the presence of salvin, a plant antibiotic. In addition, the use of sage extract helps reduce inflammation and alleviate discomfort in the throat. It contains so-called tannins.
Thanks to them, the mucous membranes are protected from irritation and further damage. The presence of flavonoids in the composition helps to reduce the permeability of cell membranes, walls of blood and lymphatic vessels.
Marshmallow contains specific substances - polysaccharides, due to which it is used as a remedy that helps reduce inflammation, relieve cough, and stimulate protective immune mechanisms.
Plantain has antiseptic and antimicrobial properties. In addition, it helps reduce the allergic reaction to infectious agents and thin the sputum. Participates in tissue regeneration and restoration of the mucous membranes of the respiratory tract due to its anti-inflammatory properties.
Vitamin C (ascorbic acid) is an antioxidant that protects cell membranes from the damaging effects of free radicals during the development of inflammation. A sufficient amount of vitamin C in the body is necessary to provide effective immune protection against infections. It stimulates the functioning of the immune system at the cellular level, activating specific cells that are the main assistants in the healing process. Ascorbic acid also acts as an antiviral component that increases the amount of interferon. Vitamin C is not synthesized in the body, so it must come from outside.
Menthol acts on cold receptors on the surface of the mucous membrane of the throat, promotes a local decrease in sensitivity, facilitates swallowing and reduces the severity of discomfort in the throat.
Use during pregnancy and breastfeeding
Contraindicated during pregnancy and lactation.
Release forms and indications
The vast majority of drugs for sore throat are available in the form of lozenges or lozenges. With the exception of three drugs.
| A drug | Release form |
| Gramicidin S | Cheek tablets |
| Ismigen | Sublingual tablets |
| Falimint* | Dragee |
All local medications for sore throat are used for infectious and inflammatory diseases of the oral cavity and pharynx. Bacterial lysates are also indicated for the prevention of exacerbations of recurrent infections (Imudon - for the prevention of diseases of the oral cavity and pharynx, and Ismigen is also used for the prevention of lower respiratory tract infections). And “Falimint” has another “non-standard” indication for drugs for sore throat: the drug is prescribed to relieve a reflex non-productive cough (for example, a smoker’s cough).
Larinal with licorice sage and eucalyptus oil tab. d/rass. in blister in pack №8x2
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Compound:
1 lozenge contains:
dry extract of sage leaves (Salviae folii extractum siccum) - 4.0 mg,
dry extract of licorice root (Glycyrrhizae radix extractum siccum) - 4.0 mg,
cetylpyridinii chloridum - 1.5 mg,
peppermint oil (Menthae piperitae aetheroleum) - 5.0 mg,
eucalyptus oil (Eucalypti aeteroleum) - 0.5 mg,
ascorbic acid (acidum ascorbicum) - 30.0 mg,
Excipients:
sorbitol (sorbrtolum) - 996.5 mg,
colloidal silicon dioxide (silicii dioxydum collodale) - 10.0 mg,
hydroxypropyl methylcellulose (hydroxyprapy methylcellulosum) - 25.0 mg,
magnesium stearate (magnesii stearas) - 25.0 mg.
pharmachologic effect
Sage has an antimicrobial effect, which is enhanced by eucalyptus oil.
Licorice stimulates the activity of the ciliated epithelium and enhances the secretory function of the mucous membranes of the upper respiratory tract, which contributes to the dilution of sputum and its rapid evacuation.
A specially selected substance - cetylpyridine chloride - destroys infectious agents.
Menthol cools and has a mild local anesthetic effect. Ascorbic acid mobilizes the body's defenses to fight infection, and also normalizes capillary permeability, which is often impaired during inflammatory processes.
Indications for use
Various diseases of the oral cavity, throat and upper respiratory tract, which are manifested by sore throat, hoarseness, dry irritable cough, inflammation of the gums and oral mucosa: sore throat, pharyngitis, laryngitis, bronchitis, stomatitis, gingivitis.
Mode of application
Slowly dissolve in the mouth:
- adults - 1 tablet every 2 - 3 hours (daily dose 6-8 tablets);
- children from 10 to 15 years old - ½ - 1 tablet every 3 - 4 hours (daily dose 4 - 5 tablets);
- children from 5 to 10 years old - ½ - ½ tablets every 3 - 4 hours (daily dose 2 - 3 tablets).
The indicated doses should not be exceeded.
After resorption of the tablet, for better effects, it is recommended to refrain from drinking and eating for ½ hour.
Contraindications
— For diseases with stagnation of bile, cirrhosis of the liver, hepatitis, hypertension.
- Pregnancy.
- Children under 5 years old.
Side effects
With increased sensitivity, allergic reactions are possible.
Storage
In a dark place, protected from moisture and out of reach of children, at a temperature not exceeding +25°C.
Shelf life: 3 years.
Side effects
All the drugs under consideration can cause allergic reactions (rash, laryngospasm, burning sensation in the mouth and other), the table shows the active ingredients or their combinations with specific side effects other than allergic ones.
| Active ingredient or combination | Side effects |
| Amylmetacresol+dichlorobenzyl alcohol+lidocaine | Temporary loss of tongue sensation |
| Benzydamine hydrochloride | Local reactions: dry mouth, numbness, burning sensation in the mouth |
| Biclotymol+enoxolone+lysozyme | Superinfection With long-term use, dysbiosis of the oral cavity |
| Gramicidin C + lidocaine hydrochloride | Temporary loss of tongue sensation |
| Gramicidin C + oxybuprocaine hydrochloride + cetylpyridinium chloride monohydrate | |
| Bacterial lysates (Imudon) | From the gastrointestinal tract: nausea, vomiting, abdominal pain Other: fever, exacerbation of bronchial asthma, cough |
| Bacterial lysates (Ismigen) | From the skin: urticaria, impetiginous dermatitis, folliculitis Others: inflammation of the salivary gland, acute laryngitis, rhinitis |
| Tyrothricin+benzocaine | Contact dermatitis, persistent decrease in sensitivity of the oral mucosa |
| Flurbiprofen | From the blood: hematopoietic disorders From the nervous system: dizziness, headache, paresthesia From the immune system: anaphylactic reactions From the cardiovascular system: heart failure, edema, increased blood pressure From the respiratory system: irritation in the throat, exacerbation of asthma , bronchospasm From the gastrointestinal tract: diarrhea, oral ulceration, nausea, pain, discomfort in the oral cavity, bloating, abdominal pain, constipation, dry mouth, dyspepsia, flatulence From the skin and subcutaneous tissues: skin rash, itching From the liver : hepatitis Mental disorders: insomnia Other: fever, pain |
| Chlorhexidine hydrochloride + ascorbic acid | From the gastrointestinal tract: irritation or inflammation of the oral mucosa, soreness of the tongue and mucous membranes, taste disturbances, tartar deposits, irritation of the gastrointestinal mucosa, nausea, vomiting, belching, epigastric pain, diarrhea. When taken for more than 7 days, the tongue, teeth, and acrylic fillings may be temporarily stained |
| Cetylpyridinium chloride + benzydamine hydrochloride | From the immune system: hypersensitivity reactions, anaphylactic reactions From the nervous system: numbness of the oral mucosa From the respiratory system: bronchospasm From the gastrointestinal tract: irritation of the oral mucosa, burning in the mouth From the skin and subcutaneous tissues: urticaria, photosensitivity , angioedema, skin itching |
| Cetylpyridinium chloride + benzocaine | From the gastrointestinal tract: nausea, abdominal pain, diarrhea |
| Cetylpyridinium chloride + lidocaine | From the gastrointestinal tract: nausea, diarrhea Local irritation of the mucous membranes of the mouth and throat, temporary numbness of the mucous membrane, difficulty swallowing |
| Cetylpyridinium chloride+tetracaine+zinc sulfate | Swallowing problems, tongue numbness |
Side effects depend on the composition of the drugs. The non-steroidal anti-inflammatory drug flurbiprofen has the most “solid” list of adverse reactions (by the way, Strepsils Intensive, which contains it, is available by prescription), and among the well-tolerated ones are the combination of lysozyme and pyridoxine (Lizobakt), which is approved during pregnancy and lactation, and ambazone.
Sage “Green Doctor” lozenges No. 20
A country
Netherlands
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.
Compound
DOSAGE FORM: lozenges COMPOSITION PER TABLET: Active ingredients: Dry sage extract…………………………..……………………………………………………… ………………………..12.50 mg Sage essential oil………………………..……………………………………………………… ….………………..2.40 mg Excipients: ascorbic acid, malic acid, sorbitol, aspartame, magnesium stearate, colloidal silicon dioxide, honey flavor, quinoline yellow E-104, indigo carmine E-132. DESCRIPTION: The tablets are flat, round, with a beveled edge, bluish-green in color with lighter and darker inclusions, with a specific odor. Both sides of the tablet are engraved with “NP” on a wood background. RELEASE FORM: lozenges. 10 tablets per PVC/Al blister. 1, 2, 3, 4, 5 blisters in a cardboard box with instructions for use.
Pharmacological properties
A combined preparation containing a complex of biologically active substances. Has anti-inflammatory, antimicrobial, expectorant effects. Has astringent properties.
Indications for use
In the complex treatment of inflammatory diseases of the upper respiratory tract (tonsillitis, laryngitis, pharyngitis) and the oral cavity (stomatitis, gingivitis).
Contraindications
Increased individual sensitivity to the components of the drug, pregnancy, breastfeeding, children under 5 years of age, acute nephritis, fructose intolerance, phenylketonuria.
Mode of application
Locally. Keep in mouth until completely absorbed, without chewing. — Adults and adolescents over 15 years of age: 6 tablets per day at intervals of 2 hours. — Children from 10 to 15 years: 4 tablets per day with an interval of 3 hours. — Children from 5 to 10 years: 3 tablets per day with an interval of 4 hours. Duration of therapy is 5-7 days.
Side effect
Allergic reactions are possible. If side effects not described in these instructions occur, you should stop taking the drug and inform your doctor.
Overdose
To date, no cases of overdose have been registered.
Interaction
Taking salvia preparations may interfere with the effects of medications that act through GABA receptors (eg, barbiturates, benzodiazepines). Concomitant use with these drugs is not recommended. Sage preparations can interact with hypoglycemic and anticonvulsants, and enhance the sedative effect of other drugs and alcohol. This medicine may affect the absorption of iron and other minerals.
special instructions
If symptoms of the disease persist or the condition worsens while using the drug for 5-7 days, you should inform your doctor. INFLUENCE ON THE ABILITY TO DRIVE VEHICLES AND MECHANISMS: The use of the drug does not affect the ability to perform potentially hazardous activities that require increased concentration and speed of psychomotor reactions (driving vehicles, working with moving mechanisms).
Purpose depending on age
| Age | Trade name |
| Children over 3 years old and adults | Imudon |
| Ismigen | |
| Lysobacter | |
| Tantum Verde | |
| Faringosept | |
| Children over 4 years old and adults | Grammidin for children |
| Grammidin Neo | |
| Grammidin with neo anesthetic | |
| Gramicidin S | |
| Septogal | |
| Septolete | |
| Septolete D | |
| Septolete Neo | |
| Children over 5 years old and adults | Agisept |
| Anti-Angin Formula | |
| Gorpils | |
| Dr. Theiss Angisept | |
| Strepsils | |
| Strepsils with vitamin C | |
| Strepsils with menthol and eucalyptus | |
| Falimint | |
| Children over 6 years old and adults | Hexalize |
| Hexoral tabs classic | |
| Neo-Angin | |
| Septolete Plus | |
| Strepsils with a warming effect | |
| Suprima-ENT | |
| Theraflu LAR Menthol | |
| Children over 12 years old and adults | Hexoral tabs extra |
| Sebidin | |
| Strepsils intensive | |
| Strepsils with cooling effect | |
| Strepsils Plus | |
| Adults (from 18 years old) | Novosept forte |
| Septolete total | |
| Stopangin 2A | |
| Stopangin 2 A forte | |
| Age restrictions are not indicated in the instructions | Laripront |
Use during pregnancy and lactation*
| Possibility of use in this category of patients | A drug |
| Not recommended during pregnancy (first trimester). Breastfeeding should be discontinued during treatment | Grammidin Neo, Grammidin with anesthetic neo, Tantum verde |
| Under the supervision of a doctor | Hexoral tabs classic, Hexoral tabs extra |
| Gorpils | |
| Strepsils | |
| Strepsils with cooling effect | |
| Strepsils Plus | |
| Strepsils with vitamin C | |
| After consultation with your doctor | Dr. Theiss Angi Sept |
| Sebidin | |
| Septolete | |
| Laripront | |
| Septolete Total | |
| As prescribed by a doctor | Faringosept |
| Carefully | Septolete Neo |
| Strepsils with menthol and eucalyptus | |
| If the expected benefit to the mother outweighs the potential risk to the fetus and child | Hexalize |
| Strepsils with a warming effect | |
| Can be used during pregnancy and breastfeeding | Lysobacter |
| In the 2nd and 3rd trimesters as prescribed by a doctor, during lactation - with caution | Anti-Angin Formula |
| Use during pregnancy is not discussed in the instructions. | Suprima-ENT |
*According to the instructions for use of the drugs.
Among the list of drugs for sore throat that are used in obstetric and gynecological practice for the treatment of pregnant and lactating women and are directly indicated in the instructions for use without consultation with a doctor as of January 2021, there is “Lizobakt”. All other drugs can only be prescribed by the attending physician.
Sage with licorice, menthol and vitamin C tablets No. 20
Name
Sage with licorice, menthol and vitamin C.
Description
The tablets are flat, round, with a beveled edge, bluish-green in color with lighter and darker inclusions, with a specific odor. Both sides of the tablet are engraved with “NP” on a wood background.
Main active ingredient
Salvia officinalis leaves extract + sage oil. FTG: Antiseptic of plant origin
Release form
Pills.
Dosage
500 mg., 20 pcs.
Compound
For one tablet: Active substances: Sage dry extract1 12.50 mg Sage essential oil 2.40 mg Excipients: ascorbic acid, malic acid, sorbitol, aspartame, magnesium stearate, colloidal anhydrous silicon dioxide, honey flavor2, quinoline yellow E-104 , indigo carmine E-132.
Note
1 the ratio of raw materials to the final product is 5.0-6.0: 1, the extract contains 10% (w/w) maltodextrin 2 composition: identical to natural flavors, natural flavors, monopropylene glycol solvent
Description
The tablets are flat, round, with a beveled edge, bluish-green in color with lighter and darker inclusions, with a specific odor. Both sides of the tablet are engraved with “NP” on a wood background.
Pharmacotherapeutic group
Other means for local treatment of diseases of the oral cavity. ATX code:
A01AD11
Pharmacological properties
A combined preparation containing a complex of biologically active substances. It has anti-inflammatory, antimicrobial, mucolytic effects. Has astringent properties.
Pharmacokinetics
The drug contains various biologically active substances; pharmacokinetic studies have not been conducted.
Indications for use
In the complex treatment of inflammatory diseases of the oral cavity and pharynx (stomatitis, gingivitis, tonsillitis, pharyngitis).
Contraindications
Increased individual sensitivity to the components of the drug. With caution: Due to the content of ascorbic acid, prescribe with caution in the following conditions: hyperoxaluria, urolithiasis, renal failure, hemochromatosis, thalassemia, polycythemia, leukemia, sideroblastic anemia, glucose-6-phosphate dehydrogenase deficiency, sickle cell anemia, progressive malignant diseases, increased blood clotting, thrombosis, tendency to thrombosis, thrombophlebitis, diabetes mellitus and conditions accompanied by high blood sugar.
Directions for use and doses
Locally. Keep in mouth until completely absorbed, without chewing. Adults: 6 tablets per day at intervals of 2 hours. The usual course of treatment is 5-7 days. The duration of the course of treatment is determined by the doctor, taking into account the characteristics of the disease, the achieved effect and tolerability of the drug.
Side effect
Allergic reactions are possible. Due to the content of ascorbic acid, the development of gastrointestinal disorders (heartburn, diarrhea, nausea, vomiting), frequent urination (pollakiuria), damage to the glomerular apparatus of the kidneys, crystalluria, formation of urate and/or oxalate stones in the kidneys and urinary tract, allergic reactions is possible. (skin rash, skin hyperemia), thrombocytosis, hyperprothrombinemia, hyperglycemia, glycosuria. If any adverse reactions occur, including those not listed in this instruction, you should stop using the drug and consult a doctor.
Overdose
An overdose when ingesting more than 15 g of sage leaves can be manifested by a feeling of heat, the development of tachycardia, dizziness and epileptic convulsions. If symptoms of overdose occur, stop using the drug and consult a doctor. Treatment is symptomatic.
Interaction with other drugs
Taking salvia preparations may interfere with the effects of medications that act through GABA receptors (eg, barbiturates, benzodiazepines). Concomitant use with these drugs is not recommended. Sage preparations can interact with hypoglycemic and anticonvulsants, and enhance the sedative effect of other drugs and alcohol. This medicine may affect the absorption of iron and other minerals. The drug is not recommended for use simultaneously with other drugs containing ascorbic acid.
Precautionary measures
It is not recommended to use the drug for more than 1 week. Due to the sorbitol content, the drug should not be taken by patients with congenital fructose intolerance. Due to the sorbitol content, when taking more than 9 tablets per day, it may have a mild laxative effect. Due to the aspartame content, the drug should not be taken by patients with phenylketonuria. If symptoms persist or worsen while using the drug, you should stop using the drug and consult a doctor.
Use during pregnancy and lactation
Safety of use during pregnancy and lactation has not been established. Due to the lack of sufficient data, use during pregnancy and lactation is contraindicated. Thujone, a component of sage leaves, may have an adverse effect on pregnancy.
Use in children
Safety of use in children under 18 years of age has not been established. Due to the lack of sufficient data, use in children under 18 years of age is not recommended.
Impact on the ability to drive a car and work with equipment
The use of the drug may affect the ability to drive a car and operate machinery. During treatment, patients are not recommended to drive or operate machinery.
Release form
10 tablets in a PVC/Al blister. 2 blisters in a cardboard box with instructions for use.
Storage conditions
At a temperature not higher than 25 °C. Keep out of the reach of children!
Best before date
3 years. Do not use after the expiration date.
Conditions for dispensing from pharmacies
Without a doctor's prescription.
Buy Sage with licorice, menthol and vitamin C, tablet 500 mg No. 20 in the pharmacy
Price for Sage with licorice, menthol and vitamin C, tablet 500 mg No. 20
Instructions for use for Sage with licorice, menthol and vitamin C, tablet 500 mg No. 20
Flavors
| Flavor | A drug |
| Pineapple | Agisept |
| Suprima-ENT | |
| Anise-licorice | Novosept Forte |
| Orange | Agisept |
| Astrasept | |
| Hexoral tabs classic, Hexoral tabs extra | |
| Gorpils | |
| Novosept Forte | |
| Rinza Lorsept, Rinza Lorsept Anesthetics | |
| Stopangin 2A | |
| Strepsils with vitamin C | |
| Suprima-ENT | |
| Orange-menthol | Astrasept |
| Cherry | Dr. Theiss Angisept |
| Neo-angin | |
| Cherry-menthol | Astrasept |
| Ginger-lemon | Astrasept |
| Classic | Agisept |
| Strawberry | Gorpils |
| Stopangin 2A | |
| Suprima-ENT | |
| Citric | Agisept |
| Astrasept | |
| Hexoral tabs classic, Hexoral tabs extra | |
| Gorpils | |
| Dr. Theiss Angi Sept | |
| Rinza Lorsept, Rinza Lorsept Anesthetics | |
| Stopangin 2A | |
| Suprima-ENT | |
| Crimson | Grammidin for children |
| Suprima-ENT | |
| Honey-lime | Septolete Plus |
| Honey-lemon | Agisept |
| Astrasept | |
| Hexoral tabs classic, Hexoral tabs extra | |
| Gorpils | |
| Novosept Forte | |
| Rinza Lorsept, Rinza Lorsept Anesthetics | |
| Strepsils | |
| Strepsils Intensive | |
| Suprima-ENT | |
| Honey-linden | Dr. Theiss Angi Sept |
| Menthol | Theraflu LAR Menthol |
| Suprima-ENT | |
| Menthol-eucalyptus | Agisept |
| Astrasept | |
| Gorpils | |
| Novosept Forte | |
| Strepsils with menthol and eucalyptus | |
| Mint Lemon | Tantum Verde |
| Mint | Grammidin Neo |
| Stopangin 2A | |
| Sea buckthorn | Dr. Theiss Angi Sept |
| Blackcurrant | Hexoral tabs classic, Hexoral tabs extra |
| Rinza Lorsept, Rinza Lorsept Anesthetics | |
| Blackcurrant-menthol | Astrasept |
| Sage | Dr. Theiss Angi Sept |
| Eucalyptus | Suprima-ENT |
Presence of sugar
| Name | Sugar | Sweeteners* |
| Adjisept classic, honey-lemon, menthol-eucalyptus | + | |
| Anti-Angin Formula | + | |
| Astrasept | + | |
| Hexalize | + | |
| Hexoral tabs classic, Hexoral tabs extra | + | |
| Gorpils | + | |
| Gramicidin S | + | |
| Grammidin for children | Aspartame, sorbitol | |
| Grammidin Neo | Sorbitol | |
| Dr. Theiss Angi Sept | + | |
| Imudon | + | |
| Laripront | + | |
| Lysobacter | + | |
| Neo-Angin | Isomalt | |
| Neo-Angin cherry | Sucralose | |
| Novosept Forte | + | |
| Rinza Lorsept, Rinza Lorsept Anesthetics | + | |
| Sebidin | + | |
| Septogal | + | |
| Septolete | + | |
| Septolete D | Maltitol, mannitol | |
| Septolete Neo | Maltitol, mannitol* | |
| Septolete Plus | ||
| Septolete Total | Isomalt, sucralose | |
| Stopangin 2A | Xylitol | |
| Strepsils | + | |
| Strepsils intensive | + | |
| Strepsils with a warming effect | + | |
| Strepsils with cooling effect | + | |
| Strepsils Plus | + | |
| Strepsils with vitamin C | + | |
| Strepsils with menthol and eucalyptus | + | |
| Suprima-ENT | + | |
| Tantum Verde | Isomaltose, aspartame | |
| Theraflu LAR Menthol | Sorbitol | |
| Falimint | + |
* Allowed for diabetes.
The vast majority of local remedies for sore throats contain sugar, but there are still preparations with sweeteners, which differ in the size of the glycemic index (GI), i.e., in the effect on blood glucose levels, and in calorie content. Among all the sugar substitutes used in the group of drugs under review, only one, sucralose, is characterized by zero GI and calorie content. Aspartame, sorbitol, and mannitol also have a GI that does not exceed zero, but they contain several kilocalories per gram (1.4, 3.5, and 9, respectively). Patients with diabetes should take medications containing maltitol with caution: its GI is 25–35 units, and its calorie content reaches 13 kilocalories per gram. For comparison, the GI of milk sugar, which is most often used as a sweetener, reaches 46 (calorie content 16 kcal), and glucose - 100 units with a calorie content of 16 kcal/1 gram.
