Oxolinic ointment: instructions for use, indications, price, reviews for papillomas, warts, stomatitis

pharmachologic effect

This product contains the active ingredient oxolin , which demonstrates antiviral activity against herpes , herpes zoster , and influenza (mainly type A2). Sensitivity to oxolin of adenoviruses, molluscum contagiosum and warts of infectious origin has been noted.

This remedy is used externally and has an antiviral effect. The mechanism of influence of the active substance is based on its ability to block the binding sites of the influenza virus with the cell membrane. The product blocks viruses on the surface of membranes, preventing the virus from entering cells.

Reviews

Patients' opinions about the effectiveness of topically applied Oxolin were divided. Some consider this ointment to be quite effective, use it successfully and recommend it to all their friends, even for the treatment of pregnant, lactating women and infants. Others, on the contrary, are confident in the complete uselessness of this medicinal drug and provide examples from their own negative experience of using it as proof.

It is worth noting that there is practically no mention of the side effects of the ointment, with the exception of a temporary burning sensation, so even if Oksolin is ineffective, there will be no harm from its use.

Pharmacokinetics and pharmacodynamics

It is not toxic, there is no systemic effect if it is applied topically. The active substance does not accumulate in the body. If the drug is applied to the mucous membranes, only 20% of the drug is absorbed. After application to the skin, only 5% of the product is absorbed. It is not irritating if the required amount and concentration have been applied and the skin at the application site has not been damaged.

Does not accumulate. Excretion occurs through the kidneys within one day.

Composition and dosage forms

The ointment is a homogeneous viscous substance of yellowish or white color. Contains the active substance - oxolin. Its concentration in 1 g of the drug, depending on the purpose, is 0.25 or 3%.

The medicine is produced by the medical industry in two forms:

in plastic or metal tubes weighing 10 and 30 g containing a 3% drug: for the treatment of skin;
in tubes of 10 g containing ointment at a concentration of 0.25%: for the treatment of mucous membranes.

The ointment base contains petroleum jelly or paraffin. During long-term storage, the product may acquire a pink tint, which does not affect its pharmacological properties.

Indications for use of Oxolinic ointment

The following indications for the use of Oxolinic ointment are noted:

viral diseases of the skin and eyes;
rhinitis of viral origin (inflammatory processes of the nasal mucosa);
lichen squamosus , vesicular and herpes zoster ;
molluscum contagiosum;
the appearance of warts ;
Dühring's dermatitis herpetiformis .

It is also used to prevent influenza, for which oxolinic ointment is applied during epidemics to prevent infection with the virus.

0.25% Oxolin is also used for stomatitis . This remedy is effective for stomatitis of herpes origin.

Therapeutic effect

Oxolin has a local antimicrobial and antiviral effect. Weaken herpes simplex viruses, adenoviruses, influenza pathogens, molluscum contagiosum and some others.

The drug is easily applied, distributed over the skin and mucous membranes, forming a thin, breathable, transparent film.

Being on the surface, oxolinic ointment prevents the penetration of pathogens from the outside into the epithelial cells.
By acting on the membranes of viral shells, the drug destroys their nucleic acids, blocking functionality and accelerating the death of pathogens.
It has a softening effect, reduces irritation and pain in the affected areas.

After application, the drug is partially absorbed through capillary vessels into the bloodstream. Inside the body it is completely neutral. Does not have a systemic effect, does not cause intoxication, does not accumulate in the blood and tissues. Oxoline particles are metabolized by the liver and are completely excreted in intestinal contents and urine within 24 hours.

Oxolinic ointment, instructions for use (Method and dosage)

If Oxolinic ointment is used, the instructions for use must be followed.

When treating viral keratitis , as well as adenoviral keratoconjunctivitis, it is necessary to apply 0.25% ointment behind the eyelid 1-3 times a day. Treatment is carried out for 3-4 days. If treatment is necessary for infants, you should definitely consult a specialist.

In order to treat viral rhinitis, you need to thoroughly lubricate the nasal mucosa 2-3 times a day for 3-4 days. For this, 0.25% ointment is used. The ointment is used similarly for children and adults to prevent influenza and ARVI . During a flu epidemic, it is necessary to practice lubrication for several weeks, and be sure to use the ointment when in contact with someone who has the flu.

Patients with different types of lichen and molluscum contagiosum should use a 3 percent ointment, which is applied 2-3 times a day to the affected areas. Treatment lasts from 2 weeks to 2 months, depending on the patient’s condition. Use during pregnancy for treatment and prevention should only be carried out after a doctor's prescription.

Use 3% Oxolinic ointment for warts . Apply to skin affected by warts. Reviews indicate that the medicine sometimes allows you to completely get rid of warts.

Indications

The main indication of oxolinic ointment is the prevention of infection with influenza and other acute respiratory viral infections in case of probable contacts with sick people or during seasonal epidemics.

The medicine has proven itself in the complex treatment of the following infections:

viral rhinitis, acute respiratory infections;
inflammation of the eyelid mucosa, keratitis, conjunctivitis;
skin warts;
scaly, herpes zoster and vesicular lichen;
Dühring's dermatitis;
molluscum contagiosum;
stomatitis of herpes origin.

The therapeutic effect of the ointment is most pronounced in the initial stages of the disease.

Analogs

Level 4 ATC code matches:
Florenal

Oftalmoferon

Oksolin

Zirgan

Oftan I'm coming

Poludan

You can find many different drugs that have similar effects. Analogues of Oxolinic ointment 3 percent - Alpizarin , Atsigerpin , Vartek , Virolex , Amiksin , Gerperax , Vivorax , Zovirax and many others. At the same time, there are no medicines containing a similar active ingredient on the market.

Side effects and interactions

Oksolin is well tolerated when used by children and adults. Negative reactions are extremely rare. In the first days of applying the drug, there may be a slight burning sensation of the mucous membranes and skin, a short-term increase in nasal discharge, decreased visual acuity, and increased lacrimation. In most cases, the discomfort gradually disappears on its own. Sometimes the ointment causes a bluish coating to appear, which is easily washed off with water.

When used together, oxolinic ointment and intranasal vasoconstrictor drops are likely to increase dryness of the mucous membranes. The problem can be solved by additional use of moisturizers.

Treatment and prevention of diseases with ointment does not cause disturbances in the speed of psychomotor reactions, concentration of attention, and does not affect the emotional state of patients. Using the drug does not require giving up work with high mental stress or driving.

Reviews of Oxolinic ointment

As a rule, users leave positive reviews about this product. Basically, the ointment is considered to be a good preventive measure, as well as an effective drug for the treatment of the common cold.

If Oxolinic ointment is used for papillomas , the reviews are also in most cases positive, but there are not so many such opinions. Sometimes they say that with long-term use the drug actually helps get rid of warts. As a positive point, the low price of the product is noted. The lack of a pronounced effect of treatment is mentioned as a negative.

Application

In the treatment of eye pathologies, lesions of the mucous membranes of the nasal cavity and mouth, as well as for the prevention of influenza, the drug is used in a concentration of 0.25%:

for keratitis and conjunctivitis, a thin strip of ointment is placed behind the lower eyelids 1–3 times a day;
intranasally: for the treatment of rhinitis and for the prevention of viral respiratory infections, a thin layer of the drug is lubricated in the nasal cavity;
for stomatitis: a small amount of ointment is distributed onto the affected areas, covering them from saliva with cotton swabs.

The drug in a 3% concentration is used in the treatment of skin diseases. It is applied in a thin layer or pointwise to areas affected by lichen, dermatitis or warts up to 4 times a day. If necessary, the skin is covered with sterile fabric breathable bandages.

The medicinal product does not require subsequent special rinsing from the skin and mucous membranes. The course of treatment depends on the severity of the disease and lasts from 2 to 10 weeks. For prevention, the product can be used once or periodically.

Oxolinic ointment is approved for use in children over 2 years of age. In some cases, in low concentrations under the supervision of a pediatrician, it can be used before this age.

Since a small part of the drug penetrates into the body, exceeding doses for external use does not lead to negative health consequences. If the ointment is accidentally swallowed, life-threatening situations also do not arise. To avoid disturbances from the digestive system, it is recommended to rinse the stomach with plenty of water and take enterosorbents. No antidotes are required.

Price of Oxolinic ointment, where to buy

The price of Oxolinic ointment 3% ranges from 30 to 90 rubles per tube, depending on the manufacturer. You can buy Oxolinic ointment 3 percent at any pharmacy. Oksolin 0.25% costs approximately 30-40 rubles. for 10 g

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine

ZdravCity

Oxolinic ointment 0.25% 10g OzonOzon LLC
74 RUR order

Pharmacy Dialogue

Oxolinic ointment 0.25% 10gMuromsky PZ
29 RUR order
Oxolinic ointment 0.25% 10gNizhpharm JSC
63 RUR order
Oxolinic ointment 0.25% 10g Sintez (Kurgan) OJSC
58 RUR order
Oxolinic ointment 0.25% 10g Altaivitamins
20 rub. order
Oxolinic ointment 0.25% 10gGreen oak grove
32 RUR order

Oksolin

Oxoline or oxolinic ointment (in “chemical” language the name of this substance sounds like dioxotetrahydroxytetrahydronaphthalene) is an antiviral drug for local and external use. It has a destructive effect on the influenza virus (the condition for this is direct “face-to-face” contact), inhibits reproduction - the formation of viral copies. Herpes simplex and herpes zoster viruses, infectious wart and molluscum contagiosum viruses, and adenoviruses are also not indifferent to the action of oxolin. But still, the main area of application of the drug is the prevention of influenza. Influenza is a type of acute respiratory viral infection, accompanied by high morbidity and the likelihood of complications that aggravate the course of the disease. Due to the fact that in the initial phase of the disease, patients walk around the street with might and main, including visiting public places, the infection spreads quickly. In this regard, the issue of protection against influenza during periods of epidemic trouble is more relevant than ever. One of the most accessible methods of preventing influenza should be considered the intranasal use of oxoline, which not only prevents the incorporation of viruses into epithelial cells of the respiratory tract, but also exhibits pronounced virucidal activity against influenza viruses of types A and B. “Oxolinka” is an antiviral drug familiar to most us since childhood. Long-term practice of using this drug has strengthened in the minds of many doctors and pharmacists the opinion that oxolin is more a tool of mechanical protection than a specific antiviral agent. However, the very fact of the presence of oxolinic ointment on pharmacy shelves for many years clearly testifies in its favor. Yes, and there is still some kind of evidence base for this drug. Oxolin was first synthesized in 1964 at the Moscow Scientific Research Chemical and Pharmaceutical Institute.

Clinical trials of the drug have confirmed its safety and effectiveness in the treatment of certain dermatological and ophthalmological viral infections. Subsequently, the activity of oxoline against the influenza virus was demonstrated. The effectiveness of the drug was assessed by the degree of its influence on the duration of the main clinical manifestations of the disease: febrile temperature, intoxication of the body, respiratory symptoms. As a result of scientific research, it was established for certain: local use of oxolinic ointment did not affect the duration of fever and symptoms of intoxication, but shortened the duration of a runny nose, reduced exudation and facilitated nasal breathing. In clinical trials of oxolin as a prophylactic during influenza epidemics, it was demonstrated that the effectiveness of the drug depends on the mode of its use. Irregular, sporadic use of oxolinic ointment was practically useless. Regular use of the drug with a frequency of at least 2 times a day for three weeks contributed to a milder course of the flu, which was manifested by a decrease in the duration of the temperature reaction. It is important that when oxolinic ointment is applied to the skin or mucous membranes, it does not have a locally irritating or resorptive toxic effect. Only 5% of oxoline is absorbed through the skin, about 20% through the mucous membranes. The drug does not accumulate in the body and leaves it completely within 24 hours, calling on the kidneys to help. To treat warts, they are lubricated with 3% ointment 2-3 times a day for 0.5-2 months. To prevent influenza, a 0.25% ointment is used, which is applied to the nasal mucosa 2-3 times a day during periods of epidemiological trouble or in case of direct contact with an infected person. Viral rhinitis is treated in the same way for 3-4 days.