Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Bishofite is a natural mineral containing a complex of minerals and trace elements ( iodine , boron , copper , iron , silicon ). Bishofite Poltava is extracted in the form of brine (oily consistency) when drilling wells 2.5 km deep and has a total mineralization of 340 g/l (like no other mineral spring). It undergoes complex processing, but after it completely retains the complex of macro- and microelements. It has a high percentage of magnesium , which is necessary for building bone tissue, regulating muscle contraction and relaxation, transmitting nerve signals, and improving immunity .
Transdermal use of the drug (magnesium chloride is quickly absorbed) is a simple and effective way to increase magnesium in the body.
It has an anti-inflammatory and analgesic effect, stimulates tissue regeneration . Strengthens muscle and connective tissue, improves blood microcirculation, activates lymph flow and metabolic processes. Very effective for stress and for improving sleep. Low toxicity , absence of allergenic and carcinogenic properties have been proven.
Pharmacokinetics
Not studied.
Bishofite in nature
Accumulations of bischofite are usually small: scattered, sometimes single inclusions, individual nests and thin layers and lenses. Bishofite is very hygroscopic, it quickly dissolves in air, easily dissolves in water and alcohol, and has a bitter taste. The color of the mineral is often colorless, water-transparent, white; colored varieties (orange and reddish-brown) are less common. The texture of bischofite rock is massive, layered or spotted. The latter arises due to the uneven distribution of impurity minerals: halite, kieserite, carnallite, sylvite, anhydrite, etc. For many decades, bischofite had the status of a rare mineral. This opinion existed even after its discovery in 1930–1950. in the Caspian depression on the Ozinki and Chelkar salt domes of bischofite rocks in bedded formation; The thickness of the layers here reaches 15-20 m. Horizons with bischofite most often have a bischofite-carnallite and carnallite-bischofite composition, but their kieserite-containing varieties are also widespread. What seemed surprising was that individual layers and interlayers were composed of almost monomineral bischofite rock with a bischofite content of 95-98%. The huge volume of exploration work for oil and gas carried out in recent decades in the territory of the Caspian basin and its surroundings has made it possible to study quite well the structure and composition of the salt-bearing section, mainly from field geophysical data and much less from well cores. This led to the discovery in the 60s. bischophyte-bearing province of the Northern Caspian region, the only one in the world so far characterized by such powerful bischophyte accumulation (Derevyagin et al., 19816). Bischofite deposits were found in various parts of the Caspian basin; unique bischofite formations were discovered on the Volga monocline. Their uniqueness lies in the fact that, firstly, the thickness of the layers of almost pure bischofite rocks reaches several tens of meters; secondly, the bischofite horizons have a regional development, extending in an almost continuous strip 10–50 km wide from north to south for more than 400 km; thirdly, the forecast reserves of bischofite are estimated at hundreds of billions of tons; fourthly, the discovery of large deposits of bischofite forced researchers to reconsider the improbability of the existence of exceptional conditions for their formation in different geological eras.
No less unique, in comparison with the bischofites of the Volga monocline, are the thick, up to 100 m, deposits of tachhydrite (2MgCl2 • CaCl2 • 12H2O), discovered in the mid-60s. in Brazil, Gabon and Congo; they contain layers and layers of bischofite. Tachhydrite was also considered a rare mineral, requiring special conditions for its formation and preservation in a fossil state. Previously, it was found in the potash deposits of Zechstein (Germany) as a secondary mineral in association with carnallite, sylvite, kieserite, boracite and other minerals of salt deposits. Geological and geophysical research, prospecting and exploratory drilling work over the past twenty years in our country and abroad have led to the discovery of new areas of bischofite accumulation. It has been established that a number of salt-bearing formations of the world of various ages, from Lower Permian to Quaternary, contain bischofites in varying amounts. Some of the salt-bearing basins are characterized by a stratal type of bischofite rock deposits, often of industrial importance (Caspian basin, Volga monocline, Dnieper-Donets basin, Pripyat trough; basins: Western European, Gabon, Congo). The information obtained about bischofite has been reviewed in numerous works by researchers from many countries, which allows us to make a brief overview of the occurrences and deposits of bischofite established in various salt-bearing basins.
Indications for use
The use of Bishofite as an external agent is indicated for:
- deforming arthrosis;
- rheumatoid arthritis;
- radiculitis ( cervicothoracic and lumbosacral );
- lumbodynia;
- osteochondrosis;
- muscle contractures;
- diseases of the neuromuscular system;
- infected wounds;
- eczema and dermatitis ;
- acne.
In the form of baths for:
- hypertension;
- vegetative-vascular dystonia;
- chronic fatigue;
- migraine;
- stress;
- insomnia;
- convulsions;
- psoriasis;
- osteoporosis.
Chemical composition
Chemical theoretical composition of bischofite: Mg - 11.96; Cl - 34.88; H2O - 53.16. It may contain Br as an isomorphic impurity, since it is isostructural with MgBr2• 6H2O. In natural primary bischofite, up to 1% Br was noted; secondary bischofite from Ozinki contains no more than 0.1% Br. Composition of bischofite from Leopoldschal (anal. König): Mg - 11.86; Cl - 35.04; H2O- [53.10]. Density 1.65.
Crystallographic characteristics
Syngony. Monoclinic. C2h3 — C2/m
The monoclinic cell can be replaced by a primitive triclinic pseudorhombohedral cell half the size.
Class. Prismatic C2h-2/m (L2PC)
Crystal structure
In the structure, each Mg atom is surrounded by six water molecules in a regular octahedron. Of the eight Cl atoms adjacent to Mg, 2Cl are closer to the Mg(H2O)6 complex and are located at two opposite ends of the line connecting the midpoints of the faces of the H2O octahedron. Thus, the structure contains Mg(H2O)6Cl2 groups, which indicates its molecular nature. The remaining six Cl atoms are located at a slightly greater distance from Mg and form a ring in a plane perpendicular to the axis of the molecule. The elongation axes of the molecules are almost exactly perpendicular to the (201) plane.
Contraindications
- benign and malignant tumors ;
- hypersensitivity;
- violation of the integrity of the skin at the sites of application;
- joint diseases in the acute stage;
- allergic reactions;
- heart rhythm disturbances;
- progressive angina ;
- circulatory disorders ІІ — ІІІ degrees;
- pregnancy.
It is prescribed with caution to elderly people, during lactation and children under 9 years of age.
Form of being in nature
The appearance of crystals . The appearance of crystals is determined by the shapes m, o, r, less often a, in isolated cases c, s and u were noted. The crystals are elongated along the c axis or along the edge of the (111) : (111) zone, short-prismatic to acicular. The edges are sometimes very smooth.
Twins along [112] with a fusion plane almost parallel to (110) and an angle between the c axes of both individuals equal to 83°04′.
Aggregates. Granular, leafy, fibrous and parallel-fibrous aggregates, clusters of needle-shaped crystals.
Instructions for use of Bishofite (Method and dosage)
Instructions for Bishofit Poltavsky
Apply externally in the form of rubbing and compresses, diluting the brine with hot water in a 1:1 ratio. An area of the body (spine or joint) is warmed with a lamp or a heating pad, the solution is lightly rubbed in and the painful area is rubbed for 3-5 minutes, after which a warming compress is applied. To do this, moisten a cotton cloth or gauze with brine, apply it to the area of pain, cover it with parchment paper, and insulate it. After removing the compress, the skin should be rinsed with warm water. The procedures are performed every other day, for a course - 10-12 procedures. In pediatric practice, Bischofite solution is used in a smaller ratio of 1:0.5. During the procedures, crystals of the drug may fall out and settle on the skin and underwear.
Electrophoresis with Bischofite is performed with a 10% aqueous solution and the drug is administered using galvanic current from both electrodes (anode and cathode). Duration 15 minutes. The course requires 10-15 daily procedures. After the procedure, the drug is not washed off the skin and a gauze bandage is applied for up to 6-8 hours.
Ointment 911 with Bischofite (more correctly, gel-balm) is intended for external use as an adjuvant for joint diseases. Contains additional extracts of golden mustache , comfrey and cinquefoil , juniper oil, lavender, fir, rosemary and eucalyptus, which enhance the effect. The use of the gel reduces pain, stimulates the production of synovial fluid, helps restore cartilage tissue and joint mobility.
The gel is rubbed into painful areas 2-3 times a day; additional insulation is not necessary. The course of treatment is 14 days, after a month the treatment is repeated.
Analogs
Level 4 ATX code matches:
CONDROnova
Gialgan Fidia
Movex Comfort
Traumeel S
Artra
Incena
Alflutop
Goal T
Piascledine 300
Chondroitin Complex
Glucosamine-Chondroitin
Rumalon
There are no structural analogues. This substance is included in body gel, solution, bath product, balms (with comfrey, golden mustache, cinquefoil and other herbs, glucosamine, bee venom) produced by different manufacturers.
You can buy dry Bishofite, which is a concentrated salt.
Reviews of Bishofite
What is Bishofite? This is a natural mineral of the chloride-magnesium-sodium complex, which also contains trace elements - iron , iodine , copper , silicon , boron . The most famous are the Volgograd and Poltava deposits of this mineral. The use of Bishofite at home for joint diseases is possible in the form of compresses and rubs. Its use is comparable to performing sanatorium procedures. For the most part, patients were satisfied with the treatment.
- “... The solution helped me with a bruised finger; it was swollen, did not bend and was very painful. I only did 2 rubbings with a warm solution and a warm compress, everything went away”;
- “... When rubbing the joints, a feeling of warmth appears and pain decreases. To get the effect, I do it in courses every two weeks”;
- “... The product is natural and effective. Before going to bed, I apply it to my joints - the pain subsides and I feel much better”;
- “... I use it in the form of compresses on the cervical and thoracic spine throughout the night. It’s true that it’s uncomfortable to sleep, everything gets crumpled, but there is an effect. I’m very pleased”;
- “... I won’t say that the pain disappeared completely, but it became much better”;
- “... In my family, Bishofite is the first remedy. A good thing. After working at the dacha, I rub myself with it or add it to the bath.”
In the remission stage for rheumatoid arthritis , deforming arthrosis , gouty arthritis and psoriasis , a bath with Bischofite is effective: add 1 liter of solution to 100 liters of water at 36-37°C. The duration of the bath is 15-20 minutes. There are 10-12 procedures per course. Baths with this mineral reduce stress, improve immunity, counteract aging, stimulate antioxidant systems and have a general strengthening effect. You can make local baths for hands and feet - take 100 ml of solution per 1 liter of warm water, the duration of the procedure is 15-20 minutes.
Reviews of the use of Bishofite Poltava are associated not only with its use for diseases of the musculoskeletal system . The tonic, regenerating and cosmetic effect of baths on the skin and nails is known. It is used in dilution in the form of compresses for the face and neck for problem skin, as well as to give tone and elasticity to the skin, eliminate swelling, and improve blood circulation.
- “... A cosmetologist advised me, and I was convinced that it works. The properties are many times better than the Dead Sea preparations”;
- “... I make masks on the face and hair in a diluted form. The problem with skin and hair loss has been resolved”;
- “... For cellulite, every other day I do body wraps with Bischofite and take baths.”
For local treatment, Bischofite gel is used, which additionally contains Vitamin PP , glycerin and gall-forming components. Reviews about the Bischofite gel are only positive - it does not cause irritation like a concentrate, is easy to apply and absorb, relieves radiculitis and arthritis , and quickly relieves pain. It is useful for athletes and people actively involved in sports, as it relieves muscle fatigue and eliminates the consequences of injuries.
- “... I used the gel for less than two weeks, but not according to the instructions, but more often - up to 5 times a day. The pain in the joint has gone away”;
- “... It’s always in my first aid kit. It relieves pain from radiculitis very well, the condition improves significantly”;
- “... It helps me a lot with neck pain, because by the end of the day after working at the computer, stiffness and pain appear. I have to rub myself with gel every day”;
- “... For me, the gel is a salvation after intense workouts in the gym. I like that it has a natural composition.”
It must be remembered that the gel and brine can only be used on 2-3 places at a time. There are many gels based on this mineral produced by different manufacturers, but today there is no release form - Bischofite ointment.
Bishofite physical properties
Optical
- Bishofite color. Colorless or white, also meat-red
- Glassy luster, sometimes matte
- Transparency. Transparent and translucent
Mechanical
- The hardness of bischofite is 1-2.
- Density of bischofite 1.65
- There is no cleavage.
- The fracture is conchoidal to uneven.
Even with minimal loads, bischofite is easily deformed due to sliding along the plane (110), the movement occurs along the edge (110): (201), the face (201) moves parallel to itself.
Chemical properties
Bishofite dissolves very easily in water and alcohol. The taste is burning, bitter.
Other properties
Heating behavior. When heated in a closed tube, bischofite becomes cloudy, cracks, and releases abundant water vapor, then HCl vapor. Under conditions of slower heating, it melts at 116.8°. The heating curve shows several thermal effects corresponding to the stages of dehydration. Dehydration of bischofite under various conditions was carried out by Serovy and Titel; MgCl2 -4H2O, MgCl2 -2H20 and MgCl2 H20 were found among the dehydration products by X-ray method.
Bishofite price, where to buy
Buying Bishofite in Moscow and other Russian cities is not difficult. The pharmacy chain offers different forms of release: gel, bath product, Bishofite Poltava heel gel.
The price of Bishofite gel 75 ml in Moscow pharmacies ranges from 42-52 rubles. In Volgograd it can be purchased for 44-53 rubles. The cost of heel gel 100 ml is 450 rubles, and bath products with Bischofite 500 ml are 100-138 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Neohalen gel-balm for the body Sustavit Bischofite with glucosamine Health without overpayment tube 125 ml KorolevPharm LLC
86 rub. order - Neohalen gel-balm for the body Sustavit Bischofite with comfrey and saber. Health without overpayment 125 ml KorolevPharm LLC
86 rub. order
- Neohalen body gel-balm Sustavit Bischofite with bee venom Health without overpayment tube 125 ml KorolevPharm LLC
86 rub. order
- Bishofite gel 75 mlInfarma 2000 LLC
92 rub. order
- 911 Gel-balm with bischofite for body 100 mlTwins Tech
80 rub. order
Pharmacy Dialogue
- 911- Gel-balm (100ml/Bishofite/d/body) Twins Tech
75 rub. order
- Shark Oil cream Bischofite with Chondroitin for body 75mlTwins Tech
123 RUR order
- Bishofite gel (75ml tube) Infarma 2000
80 rub. order
- 911 Bischofite gel-balm for body and joint pain* (100 ml) CocoRocheLab (Mirrolla)
RUB 139 order
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Pharmacy24
- Larkspur with bischofite 75ml cream-balm Elixir, Dnepropetrovsk
28 UAH. order - 911 With bischofite for the body against joint pain 100 ml gel TOV VTF "Farmakom", Ukraine
22 UAH order
- Joint with bischofite 75 ml gel LLC "Flora-pharm", Ukraine
31 UAH order
- Bishofit Poltava “Forte cold Forte cold” 100 ml “Bishofit Mg++” Ecobiz PP, Poltava
32 UAH order
- Bishofit Detoxmag 100 ml drinking solution Ecobiz PP, Poltava
50 UAH order
PaniPharmacy
- Bishofit Poltava “Crystalline concentrate” for baths 1000ml Ukraine, RAGS PMF LLC
85 UAH order
- Bishofit Poltava Gel for the back, joints and ligaments 75 ml Ukraine, RAGS PMF LLC
23 UAH order
- Bishofit Poltava “Elite” 250ml Ukraine, RAGS PMF LLC
16 UAH order
- Bishofite with needles extract 600g Ukraine, T.V.K. GROUP
46 UAH order
- DD Soap for face and body Bishofit 70g Australia, Elfa JSC
9 UAH order
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