Composition per capsule
for a dosage of 200 mg:
active substance:
nifuroxazide 200.0 mg.
Excipients:
lactitol - 300.0 mg, microcrystalline cellulose - 58.0 mg, potato starch - 18.0 mg, magnesium stearate - 6.0 mg, sucrose until the mass of the capsule contents is obtained. 630.0 mg.
hard gelatin capsules No. 00
[gelatin (up to 100%), water (14-15%), lid:
body:
quinoline yellow dye (0.3497%), sunset dye (0.0116%), titanium dioxide (0.8742%)].
Treatment methods
Treatment of diarrhea always involves complex therapy, including several groups of drugs acting in different directions.
Antimicrobial agents are the main group of drugs in the treatment of infectious diarrhea, acting directly on the bacteria that cause poisoning. It is recommended to use drugs of the nitrofuran series, which quickly and effectively cope with most pathogens of intestinal infections, are not absorbed and do not have a systemic effect (which is very important in the presence of concomitant diseases or in children), and do not suppress the growth of intestinal microflora. One of these drugs is Ecofuril, which, in addition to the antimicrobial component, contains a prebiotic. "Ecofuril" not only eliminates the cause of the infection that caused diarrhea, but also promotes the development of its own beneficial microflora. It should be noted that the sooner treatment of diarrhea with antimicrobial drugs is started, the faster the effect will occur.
Pro- and prebiotics contain cultures of lacto- and bifidobacteria or a substrate for their rapid growth and development. With diarrhea, the amount of normal microflora in the body decreases; preparations rich in lacto- and bifidobacteria help restore balance in the gastrointestinal tract and normalize digestion. Prebiotics can be prescribed in the second stage of therapy, after antimicrobial drugs, as a restorative treatment. However, the effectiveness of treatment increases with the combined use of antimicrobial drugs and prebiotics.
Electrolytes. Violation of the water-salt balance leads to the loss of a large amount of minerals. Electrolytes are mandatory in the treatment of diarrhea. You can fill the deficiency of substances with the help of special medications. Ready-made mixtures are available in pharmacies and are extremely easy to use. Before use, they must be diluted in water and taken often in small portions, along with plenty of fluids.
Sorbents. Enterotoxins are the main cause of bloating and diarrhea. When they enter the gastrointestinal tract, they have a toxic effect on the body. Adsorbents have the property of selective absorption, and like a sponge, they actively absorb waste products of pathogenic microorganisms. However, the effect of using sorbents is short-term; upon completion of their action, the symptoms of intestinal disorder return again.
Symptomatic remedies are antispasmodics and drugs that reduce intestinal motility. By relaxing the intestines, antispasmodics reduce the severity of pain. Drugs that inhibit intestinal motility reduce the contractile activity of the intestine and reduce the speed of movement of feces through it. This reduces the severity of diarrhea and pain. These groups of drugs are also not treatment. As soon as their effect wears off, all the symptoms return again. Moreover, agents that inhibit peristalsis are not recommended for infectious diarrhea, especially those occurring with an increase in body temperature, since they slow down the elimination of pathogens from the body.
Pharmacological properties
A broad-spectrum antimicrobial agent is a derivative of 5-nitrofuran. Used to treat gastrointestinal tract infections. Nifuroxazide blocks the activity of dehydrogenases and inhibits the respiratory chain, the tricarboxylic acid cycle and other biochemical reactions in the bacterial cell. Destroys the membranes of sensitive bacteria, reduces the production of toxins by microorganisms. Activates the immune system, increases phagocyte activity and complement titer.
Effective against gram-positive microorganisms:
- Staphylococcus spp.;
- Streptococcus spp.
and gram-negative microorganisms:
- Salmonella spp.;
- Klebsiella spp.;
- Enterobacter spp.;
- Escherichia coli;
- Shigella spp.;
- Proteus spp.;
- Haemophilus influenzae;
- Campilobacter spp.;
- Edwarsiella spp.;
- Citrobacter spp.;
- Vibrio cholerae;
- Yersinia enterocolitica.
Nifuroxazide does not affect the state of normal human intestinal microflora. In acute bacterial diarrhea, it restores intestinal eubiosis. When infected with enterotropic viruses, it prevents the development of bacterial superinfection.
Pharmacokinetics
After oral administration, nifuroxazide is practically not absorbed from the gastrointestinal tract and does not have a systemic effect. It exhibits antibacterial activity against sensitive species of bacteria only in the intestinal lumen. It is excreted unchanged by the intestines. The rate of elimination depends on the dose of the drug and gastrointestinal motility.
Causes
In order to effectively cope with diarrhea, it is necessary to identify the cause of this pathology.
One of the most common types is infectious diarrhea. Pathogenic bacteria enter the intestines when eating spoiled or poor-quality food and contaminated water.
Traveling abroad can cause diarrhea
Traveling abroad, especially to warm countries, or changing your permanent place of residence can also be possible causes of loose stools. This type of diarrhea is classified as traveler's diarrhea. In order not to spoil the impressions of a long-awaited vacation, it is recommended to adhere to certain rules: be careful when choosing unfamiliar food, drink bottled water, do not forget about personal hygiene, use hand sanitizer if necessary, and also be sure to take medicines for diarrhea with you on your trip.
To prevent diarrhea from taking you by surprise, it is good to have a modern and convenient antidiarrheal drug on hand. Ecofuril is a remedy for the treatment of diarrhea, aimed at eliminating the root cause of the disease and its symptoms. An antimicrobial active substance in combination with a prebiotic eliminates not only the cause of the infection that caused diarrhea, but also promotes the development of its own beneficial microflora.
Non-infectious diarrhea is often a consequence of chronic inflammation of the intestinal mucosa (enterocolitis), irritable bowel syndrome. Frequent stressful situations can also provoke chronic intestinal diseases and can cause loose stools.
Diarrhea not only disrupts your normal routine, but can also lead to even more serious health problems.
Release form
Capsules 100 mg and 200 mg. 10 capsules (with a dosage of 100 mg) or 5, 7, 8 capsules (with a dosage of 200 mg) are placed in a contour cell packaging made of polyvinyl chloride film and printed varnished aluminum foil. 30 capsules (100 mg dosage) or 16, 28 or 30 capsules (200 mg dosage) in a plastic bottle with a screw cap or a polymer jar with a screw cap. 3 blister packs (for a dosage of 100 mg) or 2 blister packs of 8 capsules each, 4 blister packs of 7 capsules each or 6 blister packs of 5 capsules each (for a dosage of 200 mg) or 1 bottle or 1 jar together with instructions for use are placed in a cardboard pack.
What threat does diarrhea pose?
Pathogenic microorganisms, entering the gastrointestinal tract in large quantities, begin to multiply quickly. During their life, toxins are released, which lead to inflammation of the intestinal mucosa and disruption of its function - the absorption of water and nutrients. Microbes, destroying beneficial microflora in the body, aggravate the course of the disease.
Microbes destroy beneficial microflora in the body
Diarrhea poses the main threat - dehydration, especially in children; due to physiological characteristics, they quickly lose critical volumes of fluid. Violation of the water-salt balance is fraught with the development of irreversible pathological processes, therefore, when the first signs of diarrhea occur, it is necessary to drink plenty of fluids - this is one of the main stages of treatment.
Indications and use
Understanding what ecofucril helps with, it is recommended to use the product for the treatment of acute and chronic diarrhea without symptoms of helminthic infestation. The danger of this pathological condition lies in the risks of dehydration. Violation of the water-salt balance can lead to serious disruptions in the functioning of various organs and the development of irreversible changes that pose a threat to health, and in severe cases, even life.
The remedy is indicated for stool disorders caused by:
- Chronic colitis. This disease is accompanied by inflammation of the mucous membrane or tissue of the large intestine.
- Chronic enterocolitis. Such pathologies are associated with inflammation of the mucosa in the small and large intestines.
When these diseases worsen, severe cramping pain in the abdomen occurs, signs of intoxication appear, and severe weakness is observed. Pathologies are often accompanied by an increase in body temperature.
Ecofuril is a drug for treating the whole family. The drug in the form of a suspension is allowed to be used for the treatment of children from one month of age in accordance with. The instructions for use describe in detail the dosage of the drug in accordance with the age of the patients. By purchasing Ecofuril, you can guarantee reliable protection for adults and children in unforeseen situations.
The duration of treatment with the drug should not exceed 7 days. As a rule, a stable result can be achieved on day 5. The improvement in the condition becomes noticeable almost after the first dose. If a positive result cannot be achieved within the first 3 days, then you should stop taking the drug and immediately consult a doctor.
Which drugs to choose for the treatment of diarrhea?
The pharmacy offers a huge number of drugs for the treatment of diarrhea. To understand which drug may be right for you, you need to ask a few simple questions:
- How does it work: on the cause or symptoms?
- How does the drug affect the microflora (does it contain a prebiotic or not)?
- Is it suitable for the whole family (“for children”, “adults”, “release form”, etc.)?
Not all medications for diarrhea can be prescribed to children
When selecting medications for diarrhea, you should be careful, since not all of them can be prescribed to children. Some of them have contraindications and restrictions for use in children, so it is important to first read the instructions for the drug.
An integrated approach to diarrhea
One of the drugs that embodies the idea of an integrated approach to treatment is the drug “Ecofuril”. "Ecofuril" contains the antimicrobial drug nifuroxazide and the prebiotic lactulose. The drug acts directly on the cause of the disease, destroying pathogenic bacteria, and at the same time helps restore healthy intestinal microflora, thereby accelerating the healing process and preventing the development of complications.
"Ecofuril" is a drug for diarrhea with a prebiotic, which is suitable for all family members, even for the youngest, starting from the age of one month. Available in two dosage forms:
Suspension with banana flavor for children from 1 month:
- For children from 1 month to 3 years, use 2-3 times a day, 2.5 ml;
- Children aged 3 to 6 years - 3 times a day, but 5 ml;
- Children aged 6 to 18 years: 5 ml 3-4 times a day;
Capsules for children over 3 years of age and adults in doses of 100 and 200 mg.
- For children from 3 to 6 years old, use a dose of 200 mg (2 capsules of 100 mg each) 3 times a day;
- For children from 6 to 18 years old, use a dose of 200 mg (2 capsules of 100 mg, or 1 capsule of 200 mg) 3-4 times a day;
- Adults - 200 mg 4 times a day.
By purchasing just one drug for your home first aid kit, you can protect both adults and children from unforeseen unpleasant situations.
To prevent diarrhea, rinse fresh vegetables and fruits thoroughly
Timely treatment may eliminate the need for other symptomatic treatments. Before use, you should consult a specialist.
To prevent diarrhea, you must follow simple rules:
- Maintain personal hygiene (wash hands, etc.);
- Thoroughly rinse fresh vegetables and fruits before eating;
- It is recommended to drink only bottled or boiled water; be careful when choosing catering establishments;
- Avoid stressful situations in everyday life.
THERE ARE CONTRAINDICATIONS. YOU SHOULD CONSULT WITH A SPECIALIST.
